-
1
-
-
0041330433
-
Receptor-mediated choreography of life and death
-
Bhardwaj A., and Aggarwal B.B. Receptor-mediated choreography of life and death. J. Clin. Immunol. 23 (2003) 317-332
-
(2003)
J. Clin. Immunol.
, vol.23
, pp. 317-332
-
-
Bhardwaj, A.1
Aggarwal, B.B.2
-
2
-
-
0032575714
-
Death receptors: signaling and modulation
-
Ashkenazi A., and Dixit V.M. Death receptors: signaling and modulation. Sciences 281 (1998) 1305-1308
-
(1998)
Sciences
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
3
-
-
0029993331
-
Apoptosis and the maintenance of homoeostasis in the immune system
-
Osborne B.A. Apoptosis and the maintenance of homoeostasis in the immune system. Curr. Opin. Immunol. 8 (1996) 245-254
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 245-254
-
-
Osborne, B.A.1
-
5
-
-
9944222054
-
Exploiting death receptor signaling pathways for tumor therapy
-
Fulda S., and Debatin K.M. Exploiting death receptor signaling pathways for tumor therapy. Biochim. Biophys. Acta 1705 (2004) 27-41
-
(2004)
Biochim. Biophys. Acta
, vol.1705
, pp. 27-41
-
-
Fulda, S.1
Debatin, K.M.2
-
7
-
-
0034630161
-
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
-
walczak H., and Krammer P.H. The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp. Cell Res. 256 (2000) 58-66
-
(2000)
Exp. Cell Res.
, vol.256
, pp. 58-66
-
-
walczak, H.1
Krammer, P.H.2
-
8
-
-
0346792725
-
TRAIL and apoptosis induction by TNF-family DRs
-
Wang S., and El-Deiry W.S. TRAIL and apoptosis induction by TNF-family DRs. Oncogene 22 (2003) 8628-8633
-
(2003)
Oncogene
, vol.22
, pp. 8628-8633
-
-
Wang, S.1
El-Deiry, W.S.2
-
9
-
-
7344233085
-
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
-
Emery J.G., McDonnell P., Burke M.B., Deen K.C., Lyn S., Silverman C., Dul E., Appelbaum E.R., Eichman C., DiPrinzio R., Dodds R.A., James I.E., Rosenberg M., Lee J.C., and Young P.R. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J. Biol. Chem. 273 (1998) 14363-14367
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14363-14367
-
-
Emery, J.G.1
McDonnell, P.2
Burke, M.B.3
Deen, K.C.4
Lyn, S.5
Silverman, C.6
Dul, E.7
Appelbaum, E.R.8
Eichman, C.9
DiPrinzio, R.10
Dodds, R.A.11
James, I.E.12
Rosenberg, M.13
Lee, J.C.14
Young, P.R.15
-
10
-
-
0037273852
-
Protein based therapeutic approaches targeting death receptors
-
French L.E., and Tschopp J. Protein based therapeutic approaches targeting death receptors. Cell Death Differ. 10 (2003) 117-123
-
(2003)
Cell Death Differ.
, vol.10
, pp. 117-123
-
-
French, L.E.1
Tschopp, J.2
-
11
-
-
0345015844
-
Death receptors
-
Wajant H. Death receptors. Essays Biochem. 39 (2003) 53-71
-
(2003)
Essays Biochem.
, vol.39
, pp. 53-71
-
-
Wajant, H.1
-
12
-
-
0036792685
-
TNF-related apoptosis-inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy
-
Wajant H., Pfizenmaier K., and Scheurich P. TNF-related apoptosis-inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy. Apoptosis 5 (2002) 449-459
-
(2002)
Apoptosis
, vol.5
, pp. 449-459
-
-
Wajant, H.1
Pfizenmaier, K.2
Scheurich, P.3
-
13
-
-
58149456883
-
Death receptors as targets for anti-cancer therapy
-
Papenfuss K., Cordier S.M., and Walczak H. Death receptors as targets for anti-cancer therapy. J. Cell. Mol. Med. 12 (2008) 2566-2585
-
(2008)
J. Cell. Mol. Med.
, vol.12
, pp. 2566-2585
-
-
Papenfuss, K.1
Cordier, S.M.2
Walczak, H.3
-
14
-
-
0035692171
-
Death receptor ligands, in particular TRAIL, to overcome drug resistance
-
de Jong S., Timmer T., Heijenbrok F.J., and de Vries E.G. Death receptor ligands, in particular TRAIL, to overcome drug resistance. Cancer Metastasis Rev. 20 (2001) 51-56
-
(2001)
Cancer Metastasis Rev.
, vol.20
, pp. 51-56
-
-
de Jong, S.1
Timmer, T.2
Heijenbrok, F.J.3
de Vries, E.G.4
-
15
-
-
0024347970
-
Monoclonal antibody-mediated tumor regression by induction of apoptosis
-
Trauth B.C., Klas C., Peters A.M., Matzku S., Möller P., Falk W., Debatin K.M., and Krammer P.H. Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 245 (1989) 301-305
-
(1989)
Science
, vol.245
, pp. 301-305
-
-
Trauth, B.C.1
Klas, C.2
Peters, A.M.3
Matzku, S.4
Möller, P.5
Falk, W.6
Debatin, K.M.7
Krammer, P.H.8
-
16
-
-
0028223847
-
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
-
Takahashi T., Tanaka M., Brannan C.I., Jenkins N.A., Copeland N.G., Suda T., and Nagata S. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76 (1994) 969-976
-
(1994)
Cell
, vol.76
, pp. 969-976
-
-
Takahashi, T.1
Tanaka, M.2
Brannan, C.I.3
Jenkins, N.A.4
Copeland, N.G.5
Suda, T.6
Nagata, S.7
-
17
-
-
0034641898
-
CD95′s deadly mission in the immune system
-
Krammer P.H. CD95′s deadly mission in the immune system. Nature 407 (2000) 789-795
-
(2000)
Nature
, vol.407
, pp. 789-795
-
-
Krammer, P.H.1
-
18
-
-
0035936797
-
The TNF and TNF receptor superfamilies: integrating mammalian biology
-
Locksley R.M., Killeen N., and Lenardo M.J. The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104 (2001) 487-501
-
(2001)
Cell
, vol.104
, pp. 487-501
-
-
Locksley, R.M.1
Killeen, N.2
Lenardo, M.J.3
-
19
-
-
0029969717
-
A death-domain-containing receptor that mediates apoptosis
-
Kitson J., Raven T., Jiang Y.P., Goeddel D.V., Giles K.M., Pun K.T., Grinham C.J., Brown R., and Farrow S.N. A death-domain-containing receptor that mediates apoptosis. Nature 384 (1996) 372-375
-
(1996)
Nature
, vol.384
, pp. 372-375
-
-
Kitson, J.1
Raven, T.2
Jiang, Y.P.3
Goeddel, D.V.4
Giles, K.M.5
Pun, K.T.6
Grinham, C.J.7
Brown, R.8
Farrow, S.N.9
-
20
-
-
10544236916
-
Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95
-
Chinnaiyan A.M., O'Rourke K., Yu G.L., Lyons R.H., Garg M., Duan D.R., Xing L., Gentz R., Ni J., and Dixit V.M. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 274 (1996) 990-992
-
(1996)
Science
, vol.274
, pp. 990-992
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Yu, G.L.3
Lyons, R.H.4
Garg, M.5
Duan, D.R.6
Xing, L.7
Gentz, R.8
Ni, J.9
Dixit, V.M.10
-
21
-
-
0030466894
-
Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-κB
-
Marsters S.A., Sheridan J.P., Donahue C.J., Pitti R.M., Gray C.L., Goddard A.D., Bauer K.D., and Ashkenazi A. Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-κB. Curr. Biol. 6 (1996) 1669-1676
-
(1996)
Curr. Biol.
, vol.6
, pp. 1669-1676
-
-
Marsters, S.A.1
Sheridan, J.P.2
Donahue, C.J.3
Pitti, R.M.4
Gray, C.L.5
Goddard, A.D.6
Bauer, K.D.7
Ashkenazi, A.8
-
22
-
-
18344385475
-
TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and function as a T-cell costimulator
-
Migone T.S., Zhang J., Luo X., Zhuang L., Chen C., Hu B., Hong J.S., Perry J.W., Chen S.F., Zhou J.X., Cho Y.H., Ullrich S., Kanakaraj P., Carrell J., Boyd E., Olsen H.S., Hu G., Pukac L., Liu D., Ni J., Kim S., Gentz R., Feng P., Moore P.A., Ruben S.M., and Wei P. TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and function as a T-cell costimulator. Immunity 16 (2002) 479-492
-
(2002)
Immunity
, vol.16
, pp. 479-492
-
-
Migone, T.S.1
Zhang, J.2
Luo, X.3
Zhuang, L.4
Chen, C.5
Hu, B.6
Hong, J.S.7
Perry, J.W.8
Chen, S.F.9
Zhou, J.X.10
Cho, Y.H.11
Ullrich, S.12
Kanakaraj, P.13
Carrell, J.14
Boyd, E.15
Olsen, H.S.16
Hu, G.17
Pukac, L.18
Liu, D.19
Ni, J.20
Kim, S.21
Gentz, R.22
Feng, P.23
Moore, P.A.24
Ruben, S.M.25
Wei, P.26
more..
-
23
-
-
0035027854
-
DR3 regulates negative selection during thymocyte development
-
Wang E.C., Thern A., Denzel A., Kitson J., Farrow S.N., and Owen M.J. DR3 regulates negative selection during thymocyte development. Mol. Cell. Biol. 21 (2001) 3451-3461
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3451-3461
-
-
Wang, E.C.1
Thern, A.2
Denzel, A.3
Kitson, J.4
Farrow, S.N.5
Owen, M.J.6
-
24
-
-
17544367410
-
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor family
-
Pitti R.M., Marsters S.A., Ruppert S., Donahue C.J., Moore A., and Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor family. J. Biol. Chem. 271 (1996) 12687-12690
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12687-12690
-
-
Pitti, R.M.1
Marsters, S.A.2
Ruppert, S.3
Donahue, C.J.4
Moore, A.5
Ashkenazi, A.6
-
25
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
Wiley S.R., Schooley K., Smolak P.J., Din W.S., Huang C.P., Nicholl J.K., Sutherland G.R., Davis-Smith T., Rauch C., Smith C.A., and Goodwin R.G. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3 (1995) 673-682
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.P.5
Nicholl, J.K.6
Sutherland, G.R.7
Davis-Smith, T.8
Rauch, C.9
Smith, C.A.10
Goodwin, R.G.11
-
26
-
-
0037418619
-
TRAIL-induced signaling and apoptosis
-
MacFarlane M. TRAIL-induced signaling and apoptosis. Toxicol. Lett. 139 (2003) 89-97
-
(2003)
Toxicol. Lett.
, vol.139
, pp. 89-97
-
-
MacFarlane, M.1
-
27
-
-
0001203366
-
Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor
-
Wu G.S., Burns T.F., Zhan Y., Alnemri E.S., and El-Deiry W.S. Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor. Cancer Res. 59 (1999) 2770-2775
-
(1999)
Cancer Res.
, vol.59
, pp. 2770-2775
-
-
Wu, G.S.1
Burns, T.F.2
Zhan, Y.3
Alnemri, E.S.4
El-Deiry, W.S.5
-
28
-
-
20044391426
-
DR5 Knockout mice are compromised in radiation-induced apoptosis
-
Finnberg N., Gruber J.J., Fei P., Rudolph D., Bric A., Kim S.H., Burns T.F., Ajuha H., Page R., Wu G.S., Chen Y., McKenna W.G., Bernhard E., Lowe S., Mak T., and El-Deiry W.S. DR5 Knockout mice are compromised in radiation-induced apoptosis. Mol. Cell. Biol. 25 (2005) 2000-2013
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 2000-2013
-
-
Finnberg, N.1
Gruber, J.J.2
Fei, P.3
Rudolph, D.4
Bric, A.5
Kim, S.H.6
Burns, T.F.7
Ajuha, H.8
Page, R.9
Wu, G.S.10
Chen, Y.11
McKenna, W.G.12
Bernhard, E.13
Lowe, S.14
Mak, T.15
El-Deiry, W.S.16
-
29
-
-
0032563275
-
Identification and functional characterization of DR6, a novel death domain-containing TNF receptor
-
Pan G.H., Bauer J.H., Haridas V., Wang S., Liu D., Yu G., Vincenz C., Aggarwal B.B., Ni J., and Dixit V.M. Identification and functional characterization of DR6, a novel death domain-containing TNF receptor. FEBS Lett. 431 (1998) 351-356
-
(1998)
FEBS Lett.
, vol.431
, pp. 351-356
-
-
Pan, G.H.1
Bauer, J.H.2
Haridas, V.3
Wang, S.4
Liu, D.5
Yu, G.6
Vincenz, C.7
Aggarwal, B.B.8
Ni, J.9
Dixit, V.M.10
-
30
-
-
0035914945
-
Impaired c-Jun amino terminal kinase activity and T-cell differentiation in death receptor 6-deficient mice
-
Zhao H., Yan M., Wang H., Erickson S., Grewal I.S., and Dixit V.M. Impaired c-Jun amino terminal kinase activity and T-cell differentiation in death receptor 6-deficient mice. J. Exp. Med. 194 (2001) 1441-1448
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1441-1448
-
-
Zhao, H.1
Yan, M.2
Wang, H.3
Erickson, S.4
Grewal, I.S.5
Dixit, V.M.6
-
32
-
-
0141726876
-
Mechanisms of ectodermal organogenesis
-
Pispa J., and Thesleff I. Mechanisms of ectodermal organogenesis. Dev. Biol. 262 (2003) 195-205
-
(2003)
Dev. Biol.
, vol.262
, pp. 195-205
-
-
Pispa, J.1
Thesleff, I.2
-
33
-
-
0032852542
-
Ectodysplasin is a collagenous trimeric type II membrane protein with a tumor necrosis factor-like domain and co-localizes with cytoskeletal structures at lateral and apical surfaces of cells
-
Ezer S., Bayés M., Elomaa O., Schlessinger D., and Kere J. Ectodysplasin is a collagenous trimeric type II membrane protein with a tumor necrosis factor-like domain and co-localizes with cytoskeletal structures at lateral and apical surfaces of cells. Hum. Mol. Genet. 8 (1999) 2079-2086
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 2079-2086
-
-
Ezer, S.1
Bayés, M.2
Elomaa, O.3
Schlessinger, D.4
Kere, J.5
-
34
-
-
0035912849
-
Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia
-
Chen Y., Molloy S.S., Thomas L., Gambee J., Bächinger H.P., Ferguson B., Zonana J., Thomas G., and Morris N.P. Mutations within a furin consensus sequence block proteolytic release of ectodysplasin-A and cause X-linked hypohidrotic ectodermal dysplasia. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 7218-7223
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 7218-7223
-
-
Chen, Y.1
Molloy, S.S.2
Thomas, L.3
Gambee, J.4
Bächinger, H.P.5
Ferguson, B.6
Zonana, J.7
Thomas, G.8
Morris, N.P.9
-
35
-
-
0035871196
-
Ectodysplasin is released by proteolytic shedding and binds to the EDAR protein
-
Elomaa O., Pulkkinen K., Hannelius U., Mikkola M., Saarialho-Kere U., and Kere J. Ectodysplasin is released by proteolytic shedding and binds to the EDAR protein. Hum. Mol. Genet. 10 (2001) 953-962
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 953-962
-
-
Elomaa, O.1
Pulkkinen, K.2
Hannelius, U.3
Mikkola, M.4
Saarialho-Kere, U.5
Kere, J.6
-
36
-
-
0031716740
-
The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats
-
Bayes M., Hartung A.J., Ezer S., Pispa J., Thesleff I., Srivastava A.K., and Kere J. The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats. Hum. Mol. Genet. 7 (1998) 1661-1669
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 1661-1669
-
-
Bayes, M.1
Hartung, A.J.2
Ezer, S.3
Pispa, J.4
Thesleff, I.5
Srivastava, A.K.6
Kere, J.7
-
37
-
-
0033761628
-
Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors
-
Yan M., Wang L.C., Hymowitz S.G., Schilbach S., Lee J., Goddard A., de Vos A.M., Gao W.Q., and Dixit V.M. Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors. Science 290 (2000) 523-527
-
(2000)
Science
, vol.290
, pp. 523-527
-
-
Yan, M.1
Wang, L.C.2
Hymowitz, S.G.3
Schilbach, S.4
Lee, J.5
Goddard, A.6
de Vos, A.M.7
Gao, W.Q.8
Dixit, V.M.9
-
38
-
-
0035093630
-
X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappa-B signaling
-
Doffinger R., Smahi A., Bessia C., Geissmann F., Feinberg J., Durandy A., Bodemer C., Kenwrick S., Dupuis-Girod S., Blanche S., Wood P., Rabia S.H., Headon D.J., Overbeek P.A., Le Deist F., Holland S.M., Belani K., Kumararatne D.S., Fischer A., Shapiro R., Conley M.E., Reimund E., Kalhoff H., Abinun M., Munnich A., Israël A., Courtois G., and Casanova J.L. X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappa-B signaling. Nat. Genet. 27 (2001) 277-285
-
(2001)
Nat. Genet.
, vol.27
, pp. 277-285
-
-
Doffinger, R.1
Smahi, A.2
Bessia, C.3
Geissmann, F.4
Feinberg, J.5
Durandy, A.6
Bodemer, C.7
Kenwrick, S.8
Dupuis-Girod, S.9
Blanche, S.10
Wood, P.11
Rabia, S.H.12
Headon, D.J.13
Overbeek, P.A.14
Le Deist, F.15
Holland, S.M.16
Belani, K.17
Kumararatne, D.S.18
Fischer, A.19
Shapiro, R.20
Conley, M.E.21
Reimund, E.22
Kalhoff, H.23
Abinun, M.24
Munnich, A.25
Israël, A.26
Courtois, G.27
Casanova, J.L.28
more..
-
39
-
-
0037160061
-
Role of TRAF3 and -6 in the activation of the NF-kappa-B and JNK pathways by X-linked ectodermal dysplasia receptor
-
Sinha S.K., Zachariah S., Quiñones H.I., Shindo M., and Chaudhary P.M. Role of TRAF3 and -6 in the activation of the NF-kappa-B and JNK pathways by X-linked ectodermal dysplasia receptor. J. Biol. Chem. 277 (2002) 44953-44961
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44953-44961
-
-
Sinha, S.K.1
Zachariah, S.2
Quiñones, H.I.3
Shindo, M.4
Chaudhary, P.M.5
-
40
-
-
0038467389
-
Stimulation of ectodermal organ development by ectodysplasin-A1
-
Mustonen T., Pispa J., Mikkola M.L., Pummila M., Kangas A.T., Pakkasjärvi L., Jaatinen R., and Thesleff I. Stimulation of ectodermal organ development by ectodysplasin-A1. Dev. Biol. 259 (2003) 123-136
-
(2003)
Dev. Biol.
, vol.259
, pp. 123-136
-
-
Mustonen, T.1
Pispa, J.2
Mikkola, M.L.3
Pummila, M.4
Kangas, A.T.5
Pakkasjärvi, L.6
Jaatinen, R.7
Thesleff, I.8
-
41
-
-
8444240419
-
Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages
-
Mustonen T., Ilmonen M., Pummila M., Kangas A.T., Laurikkala J., Jaatinen R., Pispa J., Gaide O., Schneider P., Thesleff I., and Mikkola M.L. Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages. Development 131 (2004) 4907-4919
-
(2004)
Development
, vol.131
, pp. 4907-4919
-
-
Mustonen, T.1
Ilmonen, M.2
Pummila, M.3
Kangas, A.T.4
Laurikkala, J.5
Jaatinen, R.6
Pispa, J.7
Gaide, O.8
Schneider, P.9
Thesleff, I.10
Mikkola, M.L.11
-
42
-
-
0141884392
-
Ectodysplasin regulates pattern formation in the mammalian hair coat
-
Zhang M., Brancaccio A., Weiner L., Missero C., and Brissette J.L. Ectodysplasin regulates pattern formation in the mammalian hair coat. Genesis 37 (2003) 30-37
-
(2003)
Genesis
, vol.37
, pp. 30-37
-
-
Zhang, M.1
Brancaccio, A.2
Weiner, L.3
Missero, C.4
Brissette, J.L.5
-
43
-
-
0026510312
-
The nerve growth factor receptor: a multicomponent system that mediates the actions of the neurotrophin family of proteins
-
Barker P.A., and Murphy R.A. The nerve growth factor receptor: a multicomponent system that mediates the actions of the neurotrophin family of proteins. Mol. Cel. Biochem. 110 (1992) 1-15
-
(1992)
Mol. Cel. Biochem.
, vol.110
, pp. 1-15
-
-
Barker, P.A.1
Murphy, R.A.2
-
44
-
-
0026608541
-
Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor
-
Rodriguez-Tebar A., Dechant G., Götz R., and Barde Y.A. Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor. EMBO J. 11 (1992) 917-922
-
(1992)
EMBO J.
, vol.11
, pp. 917-922
-
-
Rodriguez-Tebar, A.1
Dechant, G.2
Götz, R.3
Barde, Y.A.4
-
45
-
-
0025774207
-
High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor
-
Hempstead B.L., Martin-Zanca D., Kaplan D.R., Parada L.F., and Chao M.V. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature 350 (1991) 678-683
-
(1991)
Nature
, vol.350
, pp. 678-683
-
-
Hempstead, B.L.1
Martin-Zanca, D.2
Kaplan, D.R.3
Parada, L.F.4
Chao, M.V.5
-
46
-
-
0025735392
-
The trk proto-oncogene product: a signal transducing receptor for nerve growth factor
-
Kaplan D.R., Hempstead B.L., Martin-Zanca D., Chao M.V., and Parada L.F. The trk proto-oncogene product: a signal transducing receptor for nerve growth factor. Science 252 (1991) 554-558
-
(1991)
Science
, vol.252
, pp. 554-558
-
-
Kaplan, D.R.1
Hempstead, B.L.2
Martin-Zanca, D.3
Chao, M.V.4
Parada, L.F.5
-
47
-
-
0037276437
-
The CD95 (APO-1/Fas) DISC and beyond
-
Peter M.E., and Krammer P.H. The CD95 (APO-1/Fas) DISC and beyond. Cell Death Differ. 10 (2003) 26-35
-
(2003)
Cell Death Differ.
, vol.10
, pp. 26-35
-
-
Peter, M.E.1
Krammer, P.H.2
-
49
-
-
0037009370
-
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signaling complexes in FADD-dependent manner but can not functionally substitute caspase-8
-
Sprick M., Rieser E., Stahl H., Grosse-Wilde A., Weigand M., and Walczak H. Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signaling complexes in FADD-dependent manner but can not functionally substitute caspase-8. EMBO J. 21 (2002) 4520-4530
-
(2002)
EMBO J.
, vol.21
, pp. 4520-4530
-
-
Sprick, M.1
Rieser, E.2
Stahl, H.3
Grosse-Wilde, A.4
Weigand, M.5
Walczak, H.6
-
50
-
-
0042466637
-
Interdimer processing mechanism of procaspase-8 activation
-
Chang D.W., Xing Z., Capacio V.L., Peter M.E., and yang X. Interdimer processing mechanism of procaspase-8 activation. EMBO J. 22 (2003) 4132-4142
-
(2003)
EMBO J.
, vol.22
, pp. 4132-4142
-
-
Chang, D.W.1
Xing, Z.2
Capacio, V.L.3
Peter, M.E.4
yang, X.5
-
51
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O., and Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114 (2003) 181-190
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
52
-
-
0030970013
-
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
-
Thome M., Schneider P., Hofmann K., Fickenscher H., Meinl E., Neipel F., Mattmann C., Burns K., Bodmer J.-L., Schröter M., Scaffidl C., Krammer P.H., Peter M.E., and Tschopp J. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature 386 (1997) 517-521
-
(1997)
Nature
, vol.386
, pp. 517-521
-
-
Thome, M.1
Schneider, P.2
Hofmann, K.3
Fickenscher, H.4
Meinl, E.5
Neipel, F.6
Mattmann, C.7
Burns, K.8
Bodmer, J.-L.9
Schröter, M.10
Scaffidl, C.11
Krammer, P.H.12
Peter, M.E.13
Tschopp, J.14
-
53
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi C., Fulda S., Srinivasan A., Friesen C., Li F., Tomaselli K.J., Debatin K.M., Krammer P.H., and Peter M.E. Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 17 (1998) 1675-1687
-
(1998)
EMBO J.
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
Debatin, K.M.7
Krammer, P.H.8
Peter, M.E.9
-
55
-
-
2342611054
-
T-cell-receptor- and B-cell-receptor-mediated activation of NF-kappaB in lymphocytes
-
Weil R., and Israël A. T-cell-receptor- and B-cell-receptor-mediated activation of NF-kappaB in lymphocytes. Curr. Opin. Immunol. 3 (2004) 374-381
-
(2004)
Curr. Opin. Immunol.
, vol.3
, pp. 374-381
-
-
Weil, R.1
Israël, A.2
-
56
-
-
0032508414
-
NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and IAP2 to suppress caspase 8 activation
-
Wang C.Y., Mayo M.W., Korneluk R.G., Goeddell D.V., and Baldwin A.S. NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and IAP2 to suppress caspase 8 activation. Science 281 (1998) 1680-1683
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddell, D.V.4
Baldwin, A.S.5
-
57
-
-
18744425429
-
The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways
-
Kataoka T., Budd R.C., Holler N., Thome M., Martinon F., Irmler M., Burns K., Hahne M., Kennedy N., Kovacsovics M., and Tschopp J. The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways. Curr. Biol. 11 (2000) 640-648
-
(2000)
Curr. Biol.
, vol.11
, pp. 640-648
-
-
Kataoka, T.1
Budd, R.C.2
Holler, N.3
Thome, M.4
Martinon, F.5
Irmler, M.6
Burns, K.7
Hahne, M.8
Kennedy, N.9
Kovacsovics, M.10
Tschopp, J.11
-
58
-
-
0036179645
-
Death receptors couple to both cell proliferation and apoptosis
-
Budd R.C. Death receptors couple to both cell proliferation and apoptosis. J. Clin. Invest. 4 (2002) 437-442
-
(2002)
J. Clin. Invest.
, vol.4
, pp. 437-442
-
-
Budd, R.C.1
-
59
-
-
35348877298
-
Barriers to effective TRAIL-targeted therapy of malignancy
-
Dyer M.J., MacFarlane M., and Cohen G.M. Barriers to effective TRAIL-targeted therapy of malignancy. J. Clin. Oncol. 25 (2007) 4505-4506
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 4505-4506
-
-
Dyer, M.J.1
MacFarlane, M.2
Cohen, G.M.3
-
60
-
-
64049103030
-
TRAIL receptor signaling and modulation: Are we on the right TRAIL?
-
Mahalingam D., Szegezdi E., Keane M., Jong S., and Samali A. TRAIL receptor signaling and modulation: Are we on the right TRAIL?. Cancer Treat. Rev. 3 (2009) 280-288
-
(2009)
Cancer Treat. Rev.
, vol.3
, pp. 280-288
-
-
Mahalingam, D.1
Szegezdi, E.2
Keane, M.3
Jong, S.4
Samali, A.5
-
61
-
-
0024596722
-
A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-down-regulated with the receptor of tumor necrosis factor
-
Yonehara S., Ishii A., and Yonehara M. A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-down-regulated with the receptor of tumor necrosis factor. J. Exp. Med. 169 (1989) 1747-1756
-
(1989)
J. Exp. Med.
, vol.169
, pp. 1747-1756
-
-
Yonehara, S.1
Ishii, A.2
Yonehara, M.3
-
62
-
-
0035855626
-
Sensitization for death receptor- or drug induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer
-
Fulda S., Kufer M.U., Meyer E., van Valen F., Dockhorn-Dworniczak B., and Debatin K.M. Sensitization for death receptor- or drug induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer. Oncogene 20 (2001) 5865-5877
-
(2001)
Oncogene
, vol.20
, pp. 5865-5877
-
-
Fulda, S.1
Kufer, M.U.2
Meyer, E.3
van Valen, F.4
Dockhorn-Dworniczak, B.5
Debatin, K.M.6
-
64
-
-
0032014073
-
DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1
-
Kasibhatla S., Brunner T., Genestier L., Echeverri F., Mahboubi A., and Green D.R. DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1. Mol. Cell 1 (1998) 543-551
-
(1998)
Mol. Cell
, vol.1
, pp. 543-551
-
-
Kasibhatla, S.1
Brunner, T.2
Genestier, L.3
Echeverri, F.4
Mahboubi, A.5
Green, D.R.6
-
65
-
-
0031743648
-
p53 Activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs
-
Muller M., Wilder S., Bannasch D., Israeli D., Lehlbach K., Li-Weber M., Friedman S.L., Galle P.R., Stremmel W., Oren M., and Krammer P.H. p53 Activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs. J. Exp. Med. 188 (1998) 2033-2045
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2033-2045
-
-
Muller, M.1
Wilder, S.2
Bannasch, D.3
Israeli, D.4
Lehlbach, K.5
Li-Weber, M.6
Friedman, S.L.7
Galle, P.R.8
Stremmel, W.9
Oren, M.10
Krammer, P.H.11
-
66
-
-
0033599527
-
Stat-1-independent up-regulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs
-
Micheau O., Hammann A., Solary E., and Dimanche-boitrel M.T. Stat-1-independent up-regulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs. Biochem. Biophys. Res. Commun. 256 (1999) 603-607
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.256
, pp. 603-607
-
-
Micheau, O.1
Hammann, A.2
Solary, E.3
Dimanche-boitrel, M.T.4
-
67
-
-
0035279153
-
Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis
-
Fulda S., Meyer E., Friesen C., Susin S.A., Kroemer G., and Debatin K.M. Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis. Oncogene 20 (2001) 1063-1075
-
(2001)
Oncogene
, vol.20
, pp. 1063-1075
-
-
Fulda, S.1
Meyer, E.2
Friesen, C.3
Susin, S.A.4
Kroemer, G.5
Debatin, K.M.6
-
68
-
-
0037162833
-
Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization
-
Lassus P., Opitz-Araya X., and Lazebnik Y. Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science 297 (2002) 1352-1354
-
(2002)
Science
, vol.297
, pp. 1352-1354
-
-
Lassus, P.1
Opitz-Araya, X.2
Lazebnik, Y.3
-
69
-
-
0037057629
-
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
-
Marsden V.S., O'Connor L., O'Reilly L.A., Silke J., Metcalf D., Ekert P.G., Huang D.C., Cecconi F., Kuida K., Tomaselli K.J., Roy S., Nicholson D.W., Vaux D.L., Bouillet P., Adams J.M., and Strasser A. Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature 419 (2002) 634-637
-
(2002)
Nature
, vol.419
, pp. 634-637
-
-
Marsden, V.S.1
O'Connor, L.2
O'Reilly, L.A.3
Silke, J.4
Metcalf, D.5
Ekert, P.G.6
Huang, D.C.7
Cecconi, F.8
Kuida, K.9
Tomaselli, K.J.10
Roy, S.11
Nicholson, D.W.12
Vaux, D.L.13
Bouillet, P.14
Adams, J.M.15
Strasser, A.16
-
71
-
-
0033057792
-
Adenovirus-mediated expression of Fas ligand induces apoptosis of human prostrate cancer cells
-
Hedlund T.E., Meech S.J., Srikant S., Kratt A.S., Miller G.J., Schaack J.B., and Duke R.C. Adenovirus-mediated expression of Fas ligand induces apoptosis of human prostrate cancer cells. Cell Death Differ. 6 (1999) 175-182
-
(1999)
Cell Death Differ.
, vol.6
, pp. 175-182
-
-
Hedlund, T.E.1
Meech, S.J.2
Srikant, S.3
Kratt, A.S.4
Miller, G.J.5
Schaack, J.B.6
Duke, R.C.7
-
72
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
-
Lawrence D., Shahrokh Z., Marsters S., Achilles K., Shih D., Mounho B., Hillan, Totpal K., DeForge L., Schow P., Hooley J., Sherwood S., Pai R., Leung S., Khan L., Gliniak B., Bussiere J., Smith C.A., Strom S.S., Kelley S., Fox J.A., Thomas D., and Ashkenazi A. Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions. Nat. Med. 4 (2001) 383-385
-
(2001)
Nat. Med.
, vol.4
, pp. 383-385
-
-
Lawrence, D.1
Shahrokh, Z.2
Marsters, S.3
Achilles, K.4
Shih, D.5
Mounho, B.6
Hillan7
Totpal, K.8
DeForge, L.9
Schow, P.10
Hooley, J.11
Sherwood, S.12
Pai, R.13
Leung, S.14
Khan, L.15
Gliniak, B.16
Bussiere, J.17
Smith, C.A.18
Strom, S.S.19
Kelley, S.20
Fox, J.A.21
Thomas, D.22
Ashkenazi, A.23
more..
-
73
-
-
0034022160
-
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
-
Jo M., Kim T.H., Seol D.W., Esplen J.E., Dorko K., Billiar T.R., and Strom S.C. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat. Med. 6 (2000) 564-567
-
(2000)
Nat. Med.
, vol.6
, pp. 564-567
-
-
Jo, M.1
Kim, T.H.2
Seol, D.W.3
Esplen, J.E.4
Dorko, K.5
Billiar, T.R.6
Strom, S.C.7
-
74
-
-
0035001741
-
The potential of TRAIL for cancer chemotherapy
-
Nagane M., Huang H.J., and Canvenee W.K. The potential of TRAIL for cancer chemotherapy. Apoptosis 6 (2001) 191-197
-
(2001)
Apoptosis
, vol.6
, pp. 191-197
-
-
Nagane, M.1
Huang, H.J.2
Canvenee, W.K.3
-
75
-
-
62449168519
-
TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges
-
Bellail A.C., Qi L., Mulligan P., Chhabra V., and Hao C. TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges. Rev. Recent Clin. Trials 1 (2009) 34-41
-
(2009)
Rev. Recent Clin. Trials
, vol.1
, pp. 34-41
-
-
Bellail, A.C.1
Qi, L.2
Mulligan, P.3
Chhabra, V.4
Hao, C.5
-
76
-
-
68649113781
-
The prognostic value of TRAIL and its death receptors in cervical cancer
-
Maduro J.H., Noordhuis M.G., ten Hoor K.A., Pras E., Arts H.J., Eijsink J.J., Hollema H., Mom C.H., de Jong S., de Vries E.G., de Bock G.H., and van der Zee A.G. The prognostic value of TRAIL and its death receptors in cervical cancer. Int. J. Radiat. Oncol. Biol. Phys. 1 (2009) 203-211
-
(2009)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.1
, pp. 203-211
-
-
Maduro, J.H.1
Noordhuis, M.G.2
ten Hoor, K.A.3
Pras, E.4
Arts, H.J.5
Eijsink, J.J.6
Hollema, H.7
Mom, C.H.8
de Jong, S.9
de Vries, E.G.10
de Bock, G.H.11
van der Zee, A.G.12
-
77
-
-
0034908231
-
Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis
-
Hernandez A., Thomas R., Smith F., Sandberg J., Kim S., Chung D.H., and Evers B.M. Butyrate sensitizes human colon cancer cells to TRAIL-mediated apoptosis. Surgery 130 (2001) 265-272
-
(2001)
Surgery
, vol.130
, pp. 265-272
-
-
Hernandez, A.1
Thomas, R.2
Smith, F.3
Sandberg, J.4
Kim, S.5
Chung, D.H.6
Evers, B.M.7
-
78
-
-
0035932369
-
Sodium nitroprusside enhances TRAIL-induced apoptosis via a mitochondria dependent pathway in human colorectal carcinoma CX-1 cells
-
Lee Y.J., Lee K.H., Kim H.R., Jessup J.M., Seol D.W., Kim T.H., Billiar T.R., and Song Y.K. Sodium nitroprusside enhances TRAIL-induced apoptosis via a mitochondria dependent pathway in human colorectal carcinoma CX-1 cells. Oncogene 20 (2001) 1476-1485
-
(2001)
Oncogene
, vol.20
, pp. 1476-1485
-
-
Lee, Y.J.1
Lee, K.H.2
Kim, H.R.3
Jessup, J.M.4
Seol, D.W.5
Kim, T.H.6
Billiar, T.R.7
Song, Y.K.8
-
80
-
-
0035866369
-
Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis
-
Lacour S., Hammann A., Wotawa A., Corcos L., Solary E., and Dimanche-Boitrel M.T. Anticancer agents sensitize tumor cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated caspase-8 activation and apoptosis. Cancer Res. 61 (2001) 1645-1651
-
(2001)
Cancer Res.
, vol.61
, pp. 1645-1651
-
-
Lacour, S.1
Hammann, A.2
Wotawa, A.3
Corcos, L.4
Solary, E.5
Dimanche-Boitrel, M.T.6
-
81
-
-
0033572413
-
Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11
-
Gliniak B., and Le T. Tumor necrosis factor-related apoptosis-inducing ligand's antitumor activity in vivo is enhanced by the chemotherapeutic agent CPT-11. Cancer Res. 59 (1999) 6153-6158
-
(1999)
Cancer Res.
, vol.59
, pp. 6153-6158
-
-
Gliniak, B.1
Le, T.2
-
82
-
-
0034574785
-
The use of TNF family ligands and receptors and agents which modify their interaction as therapeutic agents
-
Gardnerova M., Blanque R., and Gardner C.R. The use of TNF family ligands and receptors and agents which modify their interaction as therapeutic agents. Curr. Drug Targets 1 (2000) 327-364
-
(2000)
Curr. Drug Targets
, vol.1
, pp. 327-364
-
-
Gardnerova, M.1
Blanque, R.2
Gardner, C.R.3
-
83
-
-
0036624741
-
Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications
-
Mitsiades N., Mitsiades C.S., Poulaki V., Chauhan D., Richardson P.G., Hideshima T., Munshi N., Treon S.P., and Anderson K.C. Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications. Blood 99 (2002) 4079-4086
-
(2002)
Blood
, vol.99
, pp. 4079-4086
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Chauhan, D.4
Richardson, P.G.5
Hideshima, T.6
Munshi, N.7
Treon, S.P.8
Anderson, K.C.9
-
84
-
-
0035674729
-
Adriamycin sensitizes the adriamycin-resistant 8226/Dox40 human multiple myeloma cells to Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-mediated (TRAIL) apoptosis
-
Jazirehi A.R., Ng C.P., Gan X.H., Schiller G., and Bonavida B. Adriamycin sensitizes the adriamycin-resistant 8226/Dox40 human multiple myeloma cells to Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-mediated (TRAIL) apoptosis. Clin. Cancer Res. 7 (2001) 3874-3883
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 3874-3883
-
-
Jazirehi, A.R.1
Ng, C.P.2
Gan, X.H.3
Schiller, G.4
Bonavida, B.5
-
85
-
-
0035849785
-
CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release
-
Rohn T.A., Wagenknecht B., Roth W., Naumann U., Gulbins E., Krammer P.H., Walczak H., and Weller M. CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release. Oncogene 20 (2001) 4128-4137
-
(2001)
Oncogene
, vol.20
, pp. 4128-4137
-
-
Rohn, T.A.1
Wagenknecht, B.2
Roth, W.3
Naumann, U.4
Gulbins, E.5
Krammer, P.H.6
Walczak, H.7
Weller, M.8
-
86
-
-
0034652486
-
Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo
-
Nagane M., Pan G., Weddle J.J., Dixit V.M., Cavenee W.K., and Huang H.J. Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo. Cancer Res. 60 (2000) 847-853
-
(2000)
Cancer Res.
, vol.60
, pp. 847-853
-
-
Nagane, M.1
Pan, G.2
Weddle, J.J.3
Dixit, V.M.4
Cavenee, W.K.5
Huang, H.J.6
-
87
-
-
0035874898
-
Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2
-
Cuello M., Ettenberg S.A., Clark A.S., Keane M.M., Posner R.H., Nau M.M., Dennis P.A., and Lipkowitz S. Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2. Cancer Res. 61 (2001) 4892-4900
-
(2001)
Cancer Res.
, vol.61
, pp. 4892-4900
-
-
Cuello, M.1
Ettenberg, S.A.2
Clark, A.S.3
Keane, M.M.4
Posner, R.H.5
Nau, M.M.6
Dennis, P.A.7
Lipkowitz, S.8
-
88
-
-
0036137141
-
TRAIL activity in human ovarian cancer cells: Potentiation of the action of cytotoxic drugs
-
Vignati S., Codegoni A., Polato F., and Broggini M. TRAIL activity in human ovarian cancer cells: Potentiation of the action of cytotoxic drugs. Eur. J. Cancer 38 (2002) 177-183
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 177-183
-
-
Vignati, S.1
Codegoni, A.2
Polato, F.3
Broggini, M.4
-
89
-
-
0034985464
-
Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells
-
Cuello M., Ettenberg S.A., Nau M.M., and Lipkowitz S. Synergistic induction of apoptosis by the combination of trail and chemotherapy in chemoresistant ovarian cancer cells. Gynecol. Oncol. 81 (2001) 380-390
-
(2001)
Gynecol. Oncol.
, vol.81
, pp. 380-390
-
-
Cuello, M.1
Ettenberg, S.A.2
Nau, M.M.3
Lipkowitz, S.4
-
90
-
-
0033083990
-
Chemotherapy augments TRAIL-induced apoptosis in breast cell lines
-
Keane M.M., Ettenberg S.A., Nau M.M., Russell E.K., and Lipkowitz S. Chemotherapy augments TRAIL-induced apoptosis in breast cell lines. Cancer Res. 59 (1999) 734-741
-
(1999)
Cancer Res.
, vol.59
, pp. 734-741
-
-
Keane, M.M.1
Ettenberg, S.A.2
Nau, M.M.3
Russell, E.K.4
Lipkowitz, S.5
-
91
-
-
0034652156
-
Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy
-
Chinnaiyan A.M., Prasad U., Shankar S., Hamstra D.A., Shanaiah M., Chenevert T.L., Ross B.D., and Rehemtulla A. Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 1754-1759
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 1754-1759
-
-
Chinnaiyan, A.M.1
Prasad, U.2
Shankar, S.3
Hamstra, D.A.4
Shanaiah, M.5
Chenevert, T.L.6
Ross, B.D.7
Rehemtulla, A.8
-
92
-
-
0037108712
-
Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID mice
-
Naka T., Sugamura K., Hylander B.L., Widmer M.B., Rustum Y.M., and Repasky E.A. Effects of tumor necrosis factor-related apoptosis-inducing ligand alone and in combination with chemotherapeutic agents on patients' colon tumors grown in SCID mice. Cancer Res. 62 (2002) 5800-5806
-
(2002)
Cancer Res.
, vol.62
, pp. 5800-5806
-
-
Naka, T.1
Sugamura, K.2
Hylander, B.L.3
Widmer, M.B.4
Rustum, Y.M.5
Repasky, E.A.6
-
93
-
-
27344456844
-
The anti-tumor effect of Apo2L/TRAIL on patient pancreatic adenocarcinomas grown as xenografts in SCID mice
-
Hylander B.L., Pitoniak R., Penetrante R.B., Gibbs J.F., Oktay D., Cheng J., and Repasky E.A. The anti-tumor effect of Apo2L/TRAIL on patient pancreatic adenocarcinomas grown as xenografts in SCID mice. J. Transl. Med. 3 (2005) 22
-
(2005)
J. Transl. Med.
, vol.3
, pp. 22
-
-
Hylander, B.L.1
Pitoniak, R.2
Penetrante, R.B.3
Gibbs, J.F.4
Oktay, D.5
Cheng, J.6
Repasky, E.A.7
-
94
-
-
0035912109
-
Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL
-
Belka C., Schmid B., Marini P., Durand E., Rudner J., Faltin H., Bamberg M., Schulze-Osthoff K., and Budach W. Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL. Oncogene 20 (2001) 2190-2196
-
(2001)
Oncogene
, vol.20
, pp. 2190-2196
-
-
Belka, C.1
Schmid, B.2
Marini, P.3
Durand, E.4
Rudner, J.5
Faltin, H.6
Bamberg, M.7
Schulze-Osthoff, K.8
Budach, W.9
-
95
-
-
0034667482
-
Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionizing radiation in leukemic cells
-
Gong B., and Almasan A. Apo2 ligand/TNF-related apoptosis-inducing ligand and death receptor 5 mediate the apoptotic signaling induced by ionizing radiation in leukemic cells. Cancer Res. 60 (2000) 5754-5760
-
(2000)
Cancer Res.
, vol.60
, pp. 5754-5760
-
-
Gong, B.1
Almasan, A.2
-
96
-
-
0035866396
-
Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression
-
Eggert A., Grotzer M.A., Zuzak T.J., Wiewrodt B.R., Ho R., Ikegaki N., and Brodeur G.M. Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression. Cancer Res. 61 (2001) 1314-1319
-
(2001)
Cancer Res.
, vol.61
, pp. 1314-1319
-
-
Eggert, A.1
Grotzer, M.A.2
Zuzak, T.J.3
Wiewrodt, B.R.4
Ho, R.5
Ikegaki, N.6
Brodeur, G.M.7
-
97
-
-
0034699330
-
Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression
-
Grotzer M.A., Eggert A., Zuzak T.J., Janss A.J., Marwaha S., Wiewrodt B.R., Ikegaki N., Brodeur G.M., and Phillips P.C. Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression. Oncogene 19 (2000) 4604-4610
-
(2000)
Oncogene
, vol.19
, pp. 4604-4610
-
-
Grotzer, M.A.1
Eggert, A.2
Zuzak, T.J.3
Janss, A.J.4
Marwaha, S.5
Wiewrodt, B.R.6
Ikegaki, N.7
Brodeur, G.M.8
Phillips, P.C.9
-
98
-
-
0035120415
-
Combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and actinomycin D induces apoptosis even in TRAIL-resistant human pancreatic cancer cells
-
Matsuzaki H., Schmied B.M., Ulrich A., Standop J., Schneider M.B., Batra S.K., Picha K.S., and Pour P.M. Combination of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and actinomycin D induces apoptosis even in TRAIL-resistant human pancreatic cancer cells. Clin. Cancer Res. 7 (2001) 407-414
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 407-414
-
-
Matsuzaki, H.1
Schmied, B.M.2
Ulrich, A.3
Standop, J.4
Schneider, M.B.5
Batra, S.K.6
Picha, K.S.7
Pour, P.M.8
-
99
-
-
0035126944
-
Cotreatment with STI-571 enhances tumor necrosis factor alpha-related apoptosis-inducing ligand (TRAIL or apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells
-
Nimmanapalli R., Porosnicu M., Nguyen D., Worthington E., O'Bryan E., Perkins C., and Bhalla K. Cotreatment with STI-571 enhances tumor necrosis factor alpha-related apoptosis-inducing ligand (TRAIL or apo-2L)-induced apoptosis of Bcr-Abl-positive human acute leukemia cells. Clin. Cancer Res. 7 (2001) 350-357
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 350-357
-
-
Nimmanapalli, R.1
Porosnicu, M.2
Nguyen, D.3
Worthington, E.4
O'Bryan, E.5
Perkins, C.6
Bhalla, K.7
-
100
-
-
0035353207
-
Ionizing radiation sensitizes erythroleukemic cells but not normal erythroblasts to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by selective up-regulation of TRAIL-R1
-
Di Pietro R., Secchiero P., Rana R., Gibellini D., Visani G., Bemis K., Zamai L., Miscia S., and Zauli G. Ionizing radiation sensitizes erythroleukemic cells but not normal erythroblasts to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by selective up-regulation of TRAIL-R1. Blood 97 (2001) 2596-2603
-
(2001)
Blood
, vol.97
, pp. 2596-2603
-
-
Di Pietro, R.1
Secchiero, P.2
Rana, R.3
Gibellini, D.4
Visani, G.5
Bemis, K.6
Zamai, L.7
Miscia, S.8
Zauli, G.9
-
101
-
-
0035195486
-
Sensitization to TRAIL-induced apoptosis and modulation of FLICE-inhibitory protein in B chronic lymphocytic leukemia by actinomycin D
-
Olsson A., Diaz T., Aguilar-Santelises M., Osterborg A., Celsing F., Jondal M., and Osorio L.M. Sensitization to TRAIL-induced apoptosis and modulation of FLICE-inhibitory protein in B chronic lymphocytic leukemia by actinomycin D. Leukemia 15 (2001) 1868-1877
-
(2001)
Leukemia
, vol.15
, pp. 1868-1877
-
-
Olsson, A.1
Diaz, T.2
Aguilar-Santelises, M.3
Osterborg, A.4
Celsing, F.5
Jondal, M.6
Osorio, L.M.7
-
102
-
-
12744261484
-
Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies
-
Inoue S., MacFarlane M., Harper N., Wheat L.M., Dyer M.J., and Cohen G.M. Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies. Cell Death Differ. 11 (2004) S193-S206
-
(2004)
Cell Death Differ.
, vol.11
-
-
Inoue, S.1
MacFarlane, M.2
Harper, N.3
Wheat, L.M.4
Dyer, M.J.5
Cohen, G.M.6
-
103
-
-
21744448694
-
Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAILR1
-
MacFarlane M., Inoue S., Kohlhaas S.L., Majid A., Harper N., Kennedy D.B., Dyer M.J., and Cohen G.M. Chronic lymphocytic leukemic cells exhibit apoptotic signaling via TRAILR1. Cell Death Differ 12 (2005) 773-782
-
(2005)
Cell Death Differ
, vol.12
, pp. 773-782
-
-
MacFarlane, M.1
Inoue, S.2
Kohlhaas, S.L.3
Majid, A.4
Harper, N.5
Kennedy, D.B.6
Dyer, M.J.7
Cohen, G.M.8
-
104
-
-
0034989624
-
In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity
-
Wuchter C., Krappmann D., Cai Z., Ruppert V., Scheidereit C., Dörken B., Ludwig W.D., and Karawajew L. In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity. Leukemia 15 (2001) 921-928
-
(2001)
Leukemia
, vol.15
, pp. 921-928
-
-
Wuchter, C.1
Krappmann, D.2
Cai, Z.3
Ruppert, V.4
Scheidereit, C.5
Dörken, B.6
Ludwig, W.D.7
Karawajew, L.8
-
105
-
-
0033975513
-
Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes
-
Leverkus M., Neumann M., Mengling T., Rauch C.T., Bröcker E.B., Krammer P.H., and Walczak H. Regulation of tumor necrosis factor-related apoptosis-inducing ligand sensitivity in primary and transformed human keratinocytes. Cancer Res. 60 (2000) 553-559
-
(2000)
Cancer Res.
, vol.60
, pp. 553-559
-
-
Leverkus, M.1
Neumann, M.2
Mengling, T.3
Rauch, C.T.4
Bröcker, E.B.5
Krammer, P.H.6
Walczak, H.7
-
106
-
-
0035863523
-
Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels
-
Nimmanapalli R., Perkins C.L., Orlando M., O'Bryan E., Nguyen D., and Bhalla K.N. Pretreatment with paclitaxel enhances apo-2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of prostate cancer cells by inducing death receptors 4 and 5 protein levels. Cancer Res. 61 (2001) 759-763
-
(2001)
Cancer Res.
, vol.61
, pp. 759-763
-
-
Nimmanapalli, R.1
Perkins, C.L.2
Orlando, M.3
O'Bryan, E.4
Nguyen, D.5
Bhalla, K.N.6
-
107
-
-
0036167572
-
Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL
-
Voelkel-Johnson C., King D.L., and Norris J.S. Resistance of prostate cancer cells to soluble TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) can be overcome by doxorubicin or adenoviral delivery of full-length TRAIL. Cancer Gene Ther. 9 (2002) 164-172
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 164-172
-
-
Voelkel-Johnson, C.1
King, D.L.2
Norris, J.S.3
-
108
-
-
0034037333
-
Apoptosis induced by death receptors
-
Schneider P., and Tschopp J. Apoptosis induced by death receptors. Pharm. Acta. Helv. 74 (2000) 281-286
-
(2000)
Pharm. Acta. Helv.
, vol.74
, pp. 281-286
-
-
Schneider, P.1
Tschopp, J.2
-
109
-
-
0036138282
-
Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil
-
Mizutani Y., Nakanishi H., Yoshida O., Fukushima M., Bonavida B., and Miki T. Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil. Eur. J. Cancer 38 (2002) 167-176
-
(2002)
Eur. J. Cancer
, vol.38
, pp. 167-176
-
-
Mizutani, Y.1
Nakanishi, H.2
Yoshida, O.3
Fukushima, M.4
Bonavida, B.5
Miki, T.6
-
110
-
-
0034747649
-
Enhanced sensitivity of bladder cancer cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis by cisplatin and carboplatin
-
Mizutani Y., Nakao M., Ogawa O., Yoshida O., Bonavida B., and Miki T. Enhanced sensitivity of bladder cancer cells to tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis by cisplatin and carboplatin. J. Urol. 165 (2001) 263-270
-
(2001)
J. Urol.
, vol.165
, pp. 263-270
-
-
Mizutani, Y.1
Nakao, M.2
Ogawa, O.3
Yoshida, O.4
Bonavida, B.5
Miki, T.6
-
111
-
-
0033839749
-
Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines
-
Yamanaka T., Shiraki K., Sugimoto K., Ito T., Fujikawa K., Ito M., Takase K., Moriyama M., Nakano T., and Suzuki A. Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines. Hepatology 32 (2000) 482-490
-
(2000)
Hepatology
, vol.32
, pp. 482-490
-
-
Yamanaka, T.1
Shiraki, K.2
Sugimoto, K.3
Ito, T.4
Fujikawa, K.5
Ito, M.6
Takase, K.7
Moriyama, M.8
Nakano, T.9
Suzuki, A.10
-
112
-
-
0033809089
-
Apoptotic responsiveness of the Ewing's sarcoma family of tumours to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)
-
Van Valen F., Fulda S., Truckenbrod B., Eckervogt V., Sonnemann J., Hillmann A., Rödl R., Hoffmann C., Winkelmann W., Schäfer L., Dockhorn-Dworniczak B., Wessel T., Boos J., Debatin K.M., and Jürgens H. Apoptotic responsiveness of the Ewing's sarcoma family of tumours to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL). Int. J. Cancer 88 (2000) 252-259
-
(2000)
Int. J. Cancer
, vol.88
, pp. 252-259
-
-
Van Valen, F.1
Fulda, S.2
Truckenbrod, B.3
Eckervogt, V.4
Sonnemann, J.5
Hillmann, A.6
Rödl, R.7
Hoffmann, C.8
Winkelmann, W.9
Schäfer, L.10
Dockhorn-Dworniczak, B.11
Wessel, T.12
Boos, J.13
Debatin, K.M.14
Jürgens, H.15
-
113
-
-
13444306459
-
Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells
-
Nebbioso A., Clarke N., Voltz E., Germain E., Ambrosino C., Bontempo P., Alvarez R., Schiavone E.M., Ferrara F., Bresciani F., Weisz A., de Lera A.R., Gronemeyer H., and Altucci L. Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells. Nat. Med. 11 (2005) 77-84
-
(2005)
Nat. Med.
, vol.11
, pp. 77-84
-
-
Nebbioso, A.1
Clarke, N.2
Voltz, E.3
Germain, E.4
Ambrosino, C.5
Bontempo, P.6
Alvarez, R.7
Schiavone, E.M.8
Ferrara, F.9
Bresciani, F.10
Weisz, A.11
de Lera, A.R.12
Gronemeyer, H.13
Altucci, L.14
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