메뉴 건너뛰기




Volumn 116, Issue 20, 2003, Pages 4053-4056

The Bcl-2-regulated apoptotic pathway

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; MEMBRANE PROTEIN; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

EID: 0242351062     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00754     Document Type: Article
Times cited : (198)

References (39)
  • 1
    • 0035853811 scopus 로고    scopus 로고
    • Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells
    • Antonsson, B., Montessuit, S., Sanchez, B. and Martinou, J. C. (2001). Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells. J. Biol. Chem. 276, 11615-11623.
    • (2001) J. Biol. Chem. , vol.276 , pp. 11615-11623
    • Antonsson, B.1    Montessuit, S.2    Sanchez, B.3    Martinou, J.C.4
  • 2
    • 0037213368 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Sensors and checkpoints for life-or-death decisions
    • Borner, C. (2003). The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol. Immunol. 39, 615-647.
    • (2003) Mol. Immunol. , vol.39 , pp. 615-647
    • Borner, C.1
  • 4
    • 0033529717 scopus 로고    scopus 로고
    • The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene
    • Conradt, B. and Horvitz, H. R. (1999). The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene. Cell 98, 317-327.
    • (1999) Cell , vol.98 , pp. 317-327
    • Conradt, B.1    Horvitz, H.R.2
  • 5
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • Cory, S. and Adams, J. M. (2002). The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2, 647-656.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 6
    • 0142117313 scopus 로고    scopus 로고
    • The Bcl-2 Family: Role in cell survival and oncogenesis
    • (in press)
    • Cory, S., Huang, D. C. S. and Adams, J. M. (2003). The Bcl-2 Family: Role in cell survival and oncogenesis. Oncogene (in press).
    • (2003) Oncogene
    • Cory, S.1    Huang, D.C.S.2    Adams, J.M.3
  • 8
    • 0033179760 scopus 로고    scopus 로고
    • Bcl-2 family members and the mitochondria in apoptosis
    • Gross, A., McDonnell, J. M. and Korsmeyer, S. J. (1999). Bcl-2 family members and the mitochondria in apoptosis. Genes Dev. 13, 1899-1911.
    • (1999) Genes Dev. , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 10
    • 0028288277 scopus 로고
    • C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
    • Hengartner, M. O. and Horvitz, H. R. (1994). C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell 76, 665-676.
    • (1994) Cell , vol.76 , pp. 665-676
    • Hengartner, M.O.1    Horvitz, H.R.2
  • 11
    • 0344608883 scopus 로고    scopus 로고
    • The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity
    • Hinds, M. G., Lackmann, M., Skea, G. L., Harrison, P. J., Huang, D. C. S. and Day, C. L. (2003). The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity. EMBO J. 22, 1497-1507.
    • (2003) EMBO J. , vol.22 , pp. 1497-1507
    • Hinds, M.G.1    Lackmann, M.2    Skea, G.L.3    Harrison, P.J.4    Huang, D.C.S.5    Day, C.L.6
  • 12
    • 0033119367 scopus 로고    scopus 로고
    • Genetic control of programmed cell death in the nematode Caenorhabditis elegans
    • Horvitz, H. R. (1999). Genetic control of programmed cell death in the nematode Caenorhabditis elegans. Cancer Res. 59, 1701s-1706s.
    • (1999) Cancer Res. , vol.59
    • Horvitz, H.R.1
  • 13
    • 0033635733 scopus 로고    scopus 로고
    • BH3-only proteins - Essential initiators of apoptotic cell death
    • Huang, D. C. S. and Strasser, A. (2000). BH3-only proteins - essential initiators of apoptotic cell death. Cell 103, 839-842.
    • (2000) Cell , vol.103 , pp. 839-842
    • Huang, D.C.S.1    Strasser, A.2
  • 17
    • 0037418238 scopus 로고    scopus 로고
    • JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
    • Lei, K. and Davis, R. J. (2003). JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc. Natl. Acad. Sci. USA 100, 2432-2437.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2432-2437
    • Lei, K.1    Davis, R.J.2
  • 18
    • 0036728834 scopus 로고    scopus 로고
    • Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
    • Letai, A., Bassik, M., Walensky, L., Sorcinelli, M., Weiler, S. and Korsmeyer, S. (2002). Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2, 183-192.
    • (2002) Cancer Cell , vol.2 , pp. 183-192
    • Letai, A.1    Bassik, M.2    Walensky, L.3    Sorcinelli, M.4    Weiler, S.5    Korsmeyer, S.6
  • 19
    • 0034508217 scopus 로고    scopus 로고
    • The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues
    • Lindsten, T., Ross, A. J., King, A., Zong, W., Rathmell, J. C., Shiels, H. A., Ulrich, E., Waymire, K. G., Mahar, P., Frauwirth, K. et al. (2000). The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues. Mol. Cell 6, 1389-1399.
    • (2000) Mol. Cell , vol.6 , pp. 1389-1399
    • Lindsten, T.1    Ross, A.J.2    King, A.3    Zong, W.4    Rathmell, J.C.5    Shiels, H.A.6    Ulrich, E.7    Waymire, K.G.8    Mahar, P.9    Frauwirth, K.10
  • 22
    • 0033578303 scopus 로고    scopus 로고
    • Bcl-2 family members do not inhibit apoptosis by binding the caspase-activator Apaf-1
    • Moriishi, K., Huang, D. C. S., Cory, S. and Adams, J. M. (1999). Bcl-2 family members do not inhibit apoptosis by binding the caspase-activator Apaf-1. Proc. Natl. Acad. Sci. USA 96, 9683-9688.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9683-9688
    • Moriishi, K.1    Huang, D.C.S.2    Cory, S.3    Adams, J.M.4
  • 24
    • 0035265686 scopus 로고    scopus 로고
    • PUMA, a novel proapoptotic gene, is induced by p53
    • Nakano, K. and Vousden, K. H. (2001). PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 7, 683-694.
    • (2001) Mol. Cell , vol.7 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 25
    • 0035844867 scopus 로고    scopus 로고
    • Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis
    • Nechushtan, A., Smith, C. L., Lamensdorf, I., Yoon, S. H. and Youle, R. J. (2001). Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis. J. Cell Biol. 153, 1265-1276.
    • (2001) J. Cell Biol. , vol.153 , pp. 1265-1276
    • Nechushtan, A.1    Smith, C.L.2    Lamensdorf, I.3    Yoon, S.H.4    Youle, R.J.5
  • 26
    • 0038046166 scopus 로고    scopus 로고
    • Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation
    • Nijhawan, D., Fang, M., Traer, E., Zhong, Q., Gao, W., Du, F. and Wang, X. (2003). Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation. Genes Dev. 17, 1475-1486.
    • (2003) Genes Dev. , vol.17 , pp. 1475-1486
    • Nijhawan, D.1    Fang, M.2    Traer, E.3    Zhong, Q.4    Gao, W.5    Du, F.6    Wang, X.7
  • 28
    • 0036097786 scopus 로고    scopus 로고
    • Keeping killers on a tight leash: Transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
    • Puthalakath, H. and Strasser, A. (2002). Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ. 9, 505-512.
    • (2002) Cell Death Differ. , vol.9 , pp. 505-512
    • Puthalakath, H.1    Strasser, A.2
  • 29
    • 0037115740 scopus 로고    scopus 로고
    • Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein
    • Roucou, X., Montessuit, S., Antonsson, B. and Martinou, J. C. (2002). Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein. Biochem. J. 368, 915-921.
    • (2002) Biochem. J. , vol.368 , pp. 915-921
    • Roucou, X.1    Montessuit, S.2    Antonsson, B.3    Martinou, J.C.4
  • 33
    • 0033713002 scopus 로고    scopus 로고
    • Structure of Bax: Coregulation of dimer formation and intracellular localization
    • Suzuki, M., Youle, R. J. and Tjandra, N. (2000). Structure of Bax: coregulation of dimer formation and intracellular localization. Cell 103, 645-654.
    • (2000) Cell , vol.103 , pp. 645-654
    • Suzuki, M.1    Youle, R.J.2    Tjandra, N.3
  • 34
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux, D. L., Cory, S. and Adams, J. M. (1988). Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335, 440-442.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 38
    • 0035876483 scopus 로고    scopus 로고
    • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
    • Zong, W. X., Lindsten, T., Ross, A. J., MacGregor, G. R. and Thompson, C. B. (2001). BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev. 15, 1481-1486.
    • (2001) Genes Dev. , vol.15 , pp. 1481-1486
    • Zong, W.X.1    Lindsten, T.2    Ross, A.J.3    MacGregor, G.R.4    Thompson, C.B.5
  • 39
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of Caspase-3
    • Zou, H., Henzel, W. J., Liu, X., Lutschg, A. and Wang, X. (1997). Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of Caspase-3. Cell 90, 405-413.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.