MSH2 ATPase domain mutation affects CTG•CAG repeat instability in transgenic mice

PLoS Genetics

Volumn 5, Issue 5, 2009, Pages

  Tomé, Stéphanie ^a   Holt, Ian ^b,c   Edelmann, Winfried ^d   Morris, Glenn E ^b,c   Munnich, Arnold ^a   Pearson, Christopher E ^e   Gourdon, Geneviève ^a  

^a INSERM   (France)

^b ROBERT JONES AND AGNES HUNT ORTHOPAEDIC HOSPITAL   (United Kingdom)

^c KEELE UNIVERSITY   (United Kingdom)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; MISMATCH REPAIR PROTEIN; PROTEIN MSH2; PROTEIN MSH3; PROTEIN MSH6; PROTEIN MUTS; PROTEIN MUTS BETA; REPETITIVE DNA; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; MSH2 PROTEIN, MOUSE; MSH3 PROTEIN, MOUSE; MSH6 PROTEIN, MOUSE; MYOTONIC DYSTROPHY PROTEIN KINASE; PRIMER DNA; PROTEIN; PROTEIN SERINE THREONINE KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASE MISPAIRING; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENOTYPE; MALE; MISMATCH REPAIR; MISSENSE MUTATION; MOUSE; NONHUMAN; NUCLEOTIDE REPEAT; POLYMERASE CHAIN REACTION; PROTEIN DOMAIN; TRANSGENIC MOUSE; ANIMAL; BRAIN; CHEMISTRY; GENETICS; GENOMIC INSTABILITY; HUMAN; METABOLISM; MOUSE MUTANT; MYOTONIC DYSTROPHY; NUCLEOTIDE SEQUENCE; OVARY; POINT MUTATION; PROTEIN TERTIARY STRUCTURE; TESTIS; TRINUCLEOTIDE REPEAT;

MUS; MUS MUSCULUS;

ADENOSINE TRIPHOSPHATASES; ANIMALS; BASE SEQUENCE; BRAIN; DNA MISMATCH REPAIR; DNA PRIMERS; DNA-BINDING PROTEINS; FEMALE; GENOMIC INSTABILITY; HUMANS; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUTS HOMOLOG 2 PROTEIN; MYOTONIC DYSTROPHY; OVARY; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; TESTIS; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 67149083322     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000482     Document Type: Article

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