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Volumn 32, Issue 21, 2004, Pages 6334-6346

Chemotherapeutic deletion of CTG repeats in lymphoblast cells from DM1 patients

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CYSTEINE; DOXORUBICIN; GLYCINE; MESYLIC ACID ETHYL ESTER; MITOMYCIN C; MITOXANTRONE; MYOTONIC DYSTROPHY PROTEIN KINASE; REPETITIVE DNA; THREONINE;

EID: 13444310994     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh976     Document Type: Article
Times cited : (51)

References (91)
  • 2
    • 0033070196 scopus 로고    scopus 로고
    • Biological implications of the DNA structures associated with disease-causing triplet repeats
    • Sinden,R.R. (1999) Biological implications of the DNA structures associated with disease-causing triplet repeats. Am. J. Hum. Genet., 64, 346-353.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 346-353
    • Sinden, R.R.1
  • 3
    • 0034640011 scopus 로고    scopus 로고
    • Fourteen and counting: Unraveling trinucleotide repeat diseases
    • Cummings,C.J. and Zoghbi,H.Y. (2000) Fourteen and counting: unraveling trinucleotide repeat diseases. Hum. Mol. Genet., 9 909-916.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 909-916
    • Cummings, C.J.1    Zoghbi, H.Y.2
  • 4
    • 0033862578 scopus 로고    scopus 로고
    • Insights from mouse models into the molecular basis of neurodegeneration
    • Heintz,N. and Zoghbi,H.Y. (2000) Insights from mouse models into the molecular basis of neurodegeneration. Annu. Rev. Physiol., 62, 779-802.
    • (2000) Annu. Rev. Physiol. , vol.62 , pp. 779-802
    • Heintz, N.1    Zoghbi, H.Y.2
  • 5
    • 0042759661 scopus 로고    scopus 로고
    • The contribution of CIS-elements to disease-associated repeat instability: Clinical and experimental evidence
    • Cleary,J.D. and Pearson,C.E. (2003) The contribution of CIS-elements to disease-associated repeat instability: clinical and experimental evidence. Cytogenet. Genome Res., 100, 25-55.
    • (2003) Cytogenet. Genome Res. , vol.100 , pp. 25-55
    • Cleary, J.D.1    Pearson, C.E.2
  • 6
    • 0002481990 scopus 로고    scopus 로고
    • Diseases with trinucleotide repeat expansion
    • Appel,S.H. (ed.), IOS Press, Amsterdam
    • Ashizawa,T. and Zoghbi,H.Y. (1997) Diseases with trinucleotide repeat expansion. In Appel,S.H. (ed.), Current Neurology IOS Press, Amsterdam, Vol. 17, pp. 79-135.
    • (1997) Current Neurology , vol.17 , pp. 79-135
    • Ashizawa, T.1    Zoghbi, H.Y.2
  • 7
    • 0032907359 scopus 로고    scopus 로고
    • Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients
    • Sato,T., Oyake,M., Nakamura,K., Nakao,K., Fukusima,Y., Onodera,O., Igarashi,S., Takano,H., Kikugawa,K., Ishida,Y. et al. (1999) Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients. Hum. Mol. Genet., 8, 99-106.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 99-106
    • Sato, T.1    Oyake, M.2    Nakamura, K.3    Nakao, K.4    Fukusima, Y.5    Onodera, O.6    Igarashi, S.7    Takano, H.8    Kikugawa, K.9    Ishida, Y.10
  • 9
    • 0034639711 scopus 로고    scopus 로고
    • Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability
    • Fortune,M.T., Vassilopoulos,C., Coolbaugh,M.I., Siciliano,M.J. and Monckton,D.G. (2000) Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability. Hum. Mol. Genet., 9, 439-445.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 439-445
    • Fortune, M.T.1    Vassilopoulos, C.2    Coolbaugh, M.I.3    Siciliano, M.J.4    Monckton, D.G.5
  • 10
    • 0031056685 scopus 로고    scopus 로고
    • Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation
    • Mangiarini,L., Sathasivam,K., Mahal,A., Mott,R., Seller,M. and Bates,G.P. (1997) Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation. Nature Genet., 15, 197-200.
    • (1997) Nature Genet. , vol.15 , pp. 197-200
    • Mangiarini, L.1    Sathasivam, K.2    Mahal, A.3    Mott, R.4    Seller, M.5    Bates, G.P.6
  • 11
    • 0034194141 scopus 로고    scopus 로고
    • Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability
    • Seznec,H., Lia-Baldini,A.S., Duros,C., Fouquet,C., Lacroix,C., Hofmann-Radvanyi,H., Junien,C. and Gourdon,G. (2000) Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability. Hum. Mol. Genet., 9, 1185-1194.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1185-1194
    • Seznec, H.1    Lia-Baldini, A.S.2    Duros, C.3    Fouquet, C.4    Lacroix, C.5    Hofmann-Radvanyi, H.6    Junien, C.7    Gourdon, G.8
  • 12
    • 0035503214 scopus 로고    scopus 로고
    • SCA12: An unusual mutation leads to an unusual spinocerebellar ataxia
    • Holmes,S.E., Hearn,E.O., Ross,C.A. and Margolis,R.L. (2001) SCA12: an unusual mutation leads to an unusual spinocerebellar ataxia. Brain Res. Bull., 56, 397-403.
    • (2001) Brain Res. Bull. , vol.56 , pp. 397-403
    • Holmes, S.E.1    Hearn, E.O.2    Ross, C.A.3    Margolis, R.L.4
  • 13
    • 0028890669 scopus 로고
    • Somatic heterogeneity of the CTG repeat in myotonic dystrophy is age and size dependent
    • Wong,L.-J.C., Ashizawa,T., Monckton,D.G., Caskey,C.T. and Richards,C.S. (1995) Somatic heterogeneity of the CTG repeat in myotonic dystrophy is age and size dependent. Am. J. Hum. Genet., 56, 114-122.
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 114-122
    • Wong, L.-J.C.1    Ashizawa, T.2    Monckton, D.G.3    Caskey, C.T.4    Richards, C.S.5
  • 15
    • 0344531040 scopus 로고    scopus 로고
    • Transgenic mouse models for myotonic dystrophy type 1 (DM1)
    • Wansink,D.G. and Wieringa,B. (2003) Transgenic mouse models for myotonic dystrophy type 1 (DM1). Cytogenet. Genome Res., 100 230-242.
    • (2003) Cytogenet. Genome Res. , vol.100 , pp. 230-242
    • Wansink, D.G.1    Wieringa, B.2
  • 16
    • 0035903189 scopus 로고    scopus 로고
    • Involvement of the nucleotide excision repair protein UvrA in instability of (CAG)·(CTG) repeat sequences in E.coli
    • Oussatcheva,E.A., Hashem,V.I., Zou,Y., Sinden,R.R. and Potaman,V.N. (2001) Involvement of the nucleotide excision repair protein UvrA in instability of (CAG)·(CTG) repeat sequences in E.coli. J. Biol. Chem., 276, 30878-30884.
    • (2001) J. Biol. Chem. , vol.276 , pp. 30878-30884
    • Oussatcheva, E.A.1    Hashem, V.I.2    Zou, Y.3    Sinden, R.R.4    Potaman, V.N.5
  • 17
    • 0037157222 scopus 로고    scopus 로고
    • Genetic assays for measuring rates of (CAG)·(CTG) repeat instability in Escherichia coli
    • Hashem,V.I., Rosche,W.A. and Sinden,R.R. (2002) Genetic assays for measuring rates of (CAG)·(CTG) repeat instability in Escherichia coli. Mutat. Res., 502, 25-37.
    • (2002) Mutat. Res. , vol.502 , pp. 25-37
    • Hashem, V.I.1    Rosche, W.A.2    Sinden, R.R.3
  • 18
    • 0033551777 scopus 로고    scopus 로고
    • Genetic instabilities in (CTG)·(CAG) repeats occur by recombination
    • Jakupciak,J.P. and Wells,R.D. (1999) Genetic instabilities in (CTG)·(CAG) repeats occur by recombination. J. Biol. Chem., 274 23468-23479.
    • (1999) J. Biol. Chem. , vol.274 , pp. 23468-23479
    • Jakupciak, J.P.1    Wells, R.D.2
  • 19
    • 0032102835 scopus 로고    scopus 로고
    • Trinucleotide repeat DNA structures: Dynamic mutations from dynamic DNA
    • Pearson,C.E. and Sinden,R.R. (1998) Trinucleotide repeat DNA structures: Dynamic mutations from dynamic DNA. Curr. Opin. Struct. Biol., 8, 321-330.
    • (1998) Curr. Opin. Struct. Biol. , vol.8 , pp. 321-330
    • Pearson, C.E.1    Sinden, R.R.2
  • 20
    • 0030737538 scopus 로고    scopus 로고
    • Trinucleotide repeats associated with human disease
    • Mitas,M. (1997) Trinucleotide repeats associated with human disease. Nucleic Acids Res., 25, 2245-2253.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2245-2253
    • Mitas, M.1
  • 21
    • 0032498265 scopus 로고    scopus 로고
    • Secondary structures in d(CGG) and d(CCG) repeat tracts
    • Darlow,J.M. and Leach,D.R.F. (1998) Secondary structures in d(CGG) and d(CCG) repeat tracts. J. Mol. Biol., 275, 3-16.
    • (1998) J. Mol. Biol. , vol.275 , pp. 3-16
    • Darlow, J.M.1    Leach, D.R.F.2
  • 22
    • 0000486352 scopus 로고    scopus 로고
    • Slipped strand DNA, dynamic mutations, and human disease
    • Wells,R.D. and Warren,S.T. (eds.), Academic Press, San Diego, CA
    • Pearson,C.E. and Sinden,R.R. (1998) Slipped strand DNA, dynamic mutations, and human disease. In Wells,R.D. and Warren,S.T. (eds.), Genetic Instabilities and Hereditary Neurological Disorders Academic Press, San Diego, CA, pp. 585-621.
    • (1998) Genetic Instabilities and Hereditary Neurological Disorders , pp. 585-621
    • Pearson, C.E.1    Sinden, R.R.2
  • 23
    • 0028874391 scopus 로고
    • CGG repeats associated with DNA instability and chromosome fragility form structures that block DNA synthesis in vitro
    • Usdin,K. and Woodford,K.J. (1995) CGG repeats associated with DNA instability and chromosome fragility form structures that block DNA synthesis in vitro. Nucleic Acids Res., 23, 4202-4209.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 4202-4209
    • Usdin, K.1    Woodford, K.J.2
  • 24
    • 0028362201 scopus 로고
    • The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure
    • Fry,M. and Loeb,L.A. (1994) The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure. Proc. Natl Acad. Sci. USA, 91, 4950-4954.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4950-4954
    • Fry, M.1    Loeb, L.A.2
  • 25
    • 0031941447 scopus 로고    scopus 로고
    • The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure
    • Bidichandani,S.I., Ashizawa,T. and Patel,P.I. (1998) The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure. Am. J. Hum. Genet., 62, 111-121.
    • (1998) Am. J. Hum. Genet. , vol.62 , pp. 111-121
    • Bidichandani, S.I.1    Ashizawa, T.2    Patel, P.I.3
  • 26
    • 0033525103 scopus 로고    scopus 로고
    • The high-resolution structure of the triplex formed by the GAA/TTC triplet repeat associated with Friedreich's ataxia
    • Mariappan,S.V., Catasti,P., Silks,L.A., III, Bradbury,E.M. and Gupta,G. (1999) The high-resolution structure of the triplex formed by the GAA/TTC triplet repeat associated with Friedreich's ataxia. J. Mol. Biol., 285, 2035-2052.
    • (1999) J. Mol. Biol. , vol.285 , pp. 2035-2052
    • Mariappan, S.V.1    Catasti, P.2    Silks III, L.A.3    Bradbury, E.M.4    Gupta, G.5
  • 27
    • 0034660695 scopus 로고    scopus 로고
    • The GAA•TTC triplet repeat expanded in Friedreich's ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner
    • Grabczyk,E. and Usdin,K. (2000) The GAA•TTC triplet repeat expanded in Friedreich's ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner. Nucleic Acids Res., 28, 2815-2822.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 2815-2822
    • Grabczyk, E.1    Usdin, K.2
  • 28
    • 0034612992 scopus 로고    scopus 로고
    • Unexpected formation of parallel duplex in GAA and TTC trinucleotide repeats of Friedreich's ataxia
    • LeProust,E.M., Pearson,C.E., Sinden,R.R. and Gao,X. (2000) Unexpected formation of parallel duplex in GAA and TTC trinucleotide repeats of Friedreich's ataxia. J. Mol. Biol., 302, 1063-1080.
    • (2000) J. Mol. Biol. , vol.302 , pp. 1063-1080
    • LeProust, E.M.1    Pearson, C.E.2    Sinden, R.R.3    Gao, X.4
  • 29
    • 0033120042 scopus 로고    scopus 로고
    • Sticky DNA: Self-association properties of long GAA · TTC repeats in R · R · Y triplex structures from Friedreich's ataxia
    • Sakamoto,N., Chastain,P.D., Parniewski,P., Ohshima,K., Pandolfo,M., Griffith,J.D. and Wells,R.D. (1999) Sticky DNA: self-association properties of long GAA · TTC repeats in R · R · Y triplex structures from Friedreich's ataxia. Mol. Cell, 3, 465-475.
    • (1999) Mol. Cell , vol.3 , pp. 465-475
    • Sakamoto, N.1    Chastain, P.D.2    Parniewski, P.3    Ohshima, K.4    Pandolfo, M.5    Griffith, J.D.6    Wells, R.D.7
  • 31
    • 0032486276 scopus 로고    scopus 로고
    • Inhibitory effects of expanded GAA·TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo
    • Ohshima,K., Montermini,L., Wells,R.D. and Pandolfo,M. (1998) Inhibitory effects of expanded GAA·TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo. J. Biol. Chem., 273, 14588-14595.
    • (1998) J. Biol. Chem. , vol.273 , pp. 14588-14595
    • Ohshima, K.1    Montermini, L.2    Wells, R.D.3    Pandolfo, M.4
  • 32
    • 0029950726 scopus 로고    scopus 로고
    • Cloning, characterization, and properties of seven triplet repeat DNA sequences
    • Ohshima,K., Kang,S., Larson,J.E. and Wells,R.D. (1996) Cloning, characterization, and properties of seven triplet repeat DNA sequences. J. Biol. Chem., 271, 16773-16783.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16773-16783
    • Ohshima, K.1    Kang, S.2    Larson, J.E.3    Wells, R.D.4
  • 34
    • 0029035379 scopus 로고
    • Expansion and deletion of CTG triplet repeats from human disease genes are determined by the direction of replication in E.coli
    • Kang,S., Jaworski,A., Ohshima,K. and Wells,R.D. (1995) Expansion and deletion of CTG triplet repeats from human disease genes are determined by the direction of replication in E.coli. Nature Genet., 10, 213-218.
    • (1995) Nature Genet. , vol.10 , pp. 213-218
    • Kang, S.1    Jaworski, A.2    Ohshima, K.3    Wells, R.D.4
  • 35
    • 0028820372 scopus 로고
    • The effects of trinucleotide repeats found in human inherited disorders on palindrome inviability in Escherichia coli suggest hairpin folding preferences in vivo
    • Darlow,J.M. and Leach,D.R.F. (1995) The effects of trinucleotide repeats found in human inherited disorders on palindrome inviability in Escherichia coli suggest hairpin folding preferences in vivo. Genetics, 141, 825-832.
    • (1995) Genetics , vol.141 , pp. 825-832
    • Darlow, J.M.1    Leach, D.R.F.2
  • 36
    • 0032498304 scopus 로고    scopus 로고
    • Evidence for two preferred hairpin folding patterns in d(CGG)•d(CCG) repeat tracts in vivo
    • Darlow,J.M. and Leach,D.F. (1998) Evidence for two preferred hairpin folding patterns in d(CGG)•d(CCG) repeat tracts in vivo. J. Mol. Biol., 275, 17-23.
    • (1998) J. Mol. Biol. , vol.275 , pp. 17-23
    • Darlow, J.M.1    Leach, D.F.2
  • 37
    • 0030895078 scopus 로고    scopus 로고
    • Stability of a CTG/CAG trinucleotide repeat in yeast is dependent on its orientation in the genome
    • Freudenreich,C.H., Stavenhagen,J.B. and Zakian,V.A. (1997) Stability of a CTG/CAG trinucleotide repeat in yeast is dependent on its orientation in the genome. Mol. Cell. Biol., 17, 2090-2098.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2090-2098
    • Freudenreich, C.H.1    Stavenhagen, J.B.2    Zakian, V.A.3
  • 38
    • 0036578758 scopus 로고    scopus 로고
    • Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells
    • Cleary,J.D., Nichol,K., Wang,Y.H. and Pearson,C.E. (2002) Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells. Nature Genet., 31, 37-46.
    • (2002) Nature Genet. , vol.31 , pp. 37-46
    • Cleary, J.D.1    Nichol, K.2    Wang, Y.H.3    Pearson, C.E.4
  • 39
    • 0033895728 scopus 로고    scopus 로고
    • The impact of lagging strand replication mutations on the stability of CAG repeat tracts in yeast
    • Ireland,M.J., Reinke,S.S. and Livingston,D.M. (2000) The impact of lagging strand replication mutations on the stability of CAG repeat tracts in yeast. Genetics, 155, 1657-1665.
    • (2000) Genetics , vol.155 , pp. 1657-1665
    • Ireland, M.J.1    Reinke, S.S.2    Livingston, D.M.3
  • 40
    • 0032779262 scopus 로고    scopus 로고
    • The effect of DNA replication mutations on CAG tract stability in yeast
    • Schweitzer,J.K. and Livingston,D.M. (1999) The effect of DNA replication mutations on CAG tract stability in yeast. Genetics, 152, 953-963.
    • (1999) Genetics , vol.152 , pp. 953-963
    • Schweitzer, J.K.1    Livingston, D.M.2
  • 41
    • 0026419949 scopus 로고
    • Preferential DNA secondary structure mutagenesis in the lagging strand of replication in E.coli
    • Trinh,T.Q. and Sinden,R.R. (1991) Preferential DNA secondary structure mutagenesis in the lagging strand of replication in E.coli. Nature, 352, 544-547.
    • (1991) Nature , vol.352 , pp. 544-547
    • Trinh, T.Q.1    Sinden, R.R.2
  • 42
    • 0026352538 scopus 로고
    • On the deletion of inverted repeated DNA in Escherichia coli: Effects of length, thermal stability, and cruciform formation in vivo
    • Sinden,R.R., Zheng,G., Brankamp,R.G. and Allen,K.N. (1991) On the deletion of inverted repeated DNA in Escherichia coli: Effects of length, thermal stability, and cruciform formation in vivo. Genetics, 129, 991-1005.
    • (1991) Genetics , vol.129 , pp. 991-1005
    • Sinden, R.R.1    Zheng, G.2    Brankamp, R.G.3    Allen, K.N.4
  • 46
    • 0030725454 scopus 로고    scopus 로고
    • Trinucleotide repeats affect DNA replication in vivo
    • Samadashwily,G.M., Raca,G. and Mirkin,S.M. (1997) Trinucleotide repeats affect DNA replication in vivo. Nature Genet. 17, 298-304.
    • (1997) Nature Genet. , vol.17 , pp. 298-304
    • Samadashwily, G.M.1    Raca, G.2    Mirkin, S.M.3
  • 47
    • 0142027842 scopus 로고    scopus 로고
    • Mutations in yeast replication proteins that increase CAG/CTG expansions also increase repeat fragility
    • Callahan,J.L., Andrews,K.J., Zakian,V.A. and Freudenreich,C.H. (2003) Mutations in yeast replication proteins that increase CAG/CTG expansions also increase repeat fragility. Mol. Cell. Biol., 23, 7849-7860.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 7849-7860
    • Callahan, J.L.1    Andrews, K.J.2    Zakian, V.A.3    Freudenreich, C.H.4
  • 48
    • 0032488872 scopus 로고    scopus 로고
    • Expansion and length-dependent fragility of CTG repeats in yeast
    • Freudenreich,C.H., Kantrow,S.M. and Zakian,V.A. (1998) Expansion and length-dependent fragility of CTG repeats in yeast. Science, 279, 853-856.
    • (1998) Science , vol.279 , pp. 853-856
    • Freudenreich, C.H.1    Kantrow, S.M.2    Zakian, V.A.3
  • 49
    • 13444253858 scopus 로고    scopus 로고
    • Structure-forming CAG/CTG repeat sequences are sensitive to breakage in the absence of Mrc1 checkpoint function and S-phase checkpoint signaling: Implications for trinucleotide repeat expansion diseases
    • Freudenreich,C.H. and Lahiri,M. (2004) Structure-forming CAG/CTG repeat sequences are sensitive to breakage in the absence of Mrc1 checkpoint function and S-phase checkpoint signaling: implications for trinucleotide repeat expansion diseases. Cell Cycle, 3.
    • (2004) Cell Cycle , vol.3
    • Freudenreich, C.H.1    Lahiri, M.2
  • 50
    • 3242658268 scopus 로고    scopus 로고
    • Expanded CAG repeats activate the DNA damage checkpoint pathway
    • Lahiri,M., Gustafson,T.L., Majors,E.R. and Freudenreich,C.H. (2004) Expanded CAG repeats activate the DNA damage checkpoint pathway. Mol. Cell, 15, 287-293.
    • (2004) Mol. Cell , vol.15 , pp. 287-293
    • Lahiri, M.1    Gustafson, T.L.2    Majors, E.R.3    Freudenreich, C.H.4
  • 51
    • 1942422156 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability
    • Liu,Y., Zhang,H., Veeraraghavan,J., Bambara,R.A. and Freudenreich,C.H. (2004) Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability. Mol. Cell. Biol., 24, 4049-4064.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 4049-4064
    • Liu, Y.1    Zhang, H.2    Veeraraghavan, J.3    Bambara, R.A.4    Freudenreich, C.H.5
  • 53
    • 0842287698 scopus 로고    scopus 로고
    • DNA double-strand break repair by homologous recombination
    • Dudas,A. and Chovanec,M. (2004) DNA double-strand break repair by homologous recombination. Mutat. Res., 566, 131-167.
    • (2004) Mutat. Res. , vol.566 , pp. 131-167
    • Dudas, A.1    Chovanec, M.2
  • 54
    • 0036336673 scopus 로고    scopus 로고
    • DNA double-strand break repair by homologous recombination
    • van den Bosch,M., Lohman,P.H. and Pastink,A. (2002) DNA double-strand break repair by homologous recombination. Biol. Chem. 383, 873-892.
    • (2002) Biol. Chem. , vol.383 , pp. 873-892
    • van den Bosch, M.1    Lohman, P.H.2    Pastink, A.3
  • 55
    • 0036900120 scopus 로고    scopus 로고
    • Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair
    • table
    • Symington,L.S. (2002) Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol. Mol. Biol. Rev., 66, 630-70, table.
    • (2002) Microbiol. Mol. Biol. Rev. , vol.66 , pp. 630-670
    • Symington, L.S.1
  • 56
    • 0942268167 scopus 로고    scopus 로고
    • Repair of DNA double strand breaks by non-homologous end joining
    • Lees-Miller,S.P. and Meek,K. (2003) Repair of DNA double strand breaks by non-homologous end joining. Biochimie, 85, 1161-1173.
    • (2003) Biochimie , vol.85 , pp. 1161-1173
    • Lees-Miller, S.P.1    Meek, K.2
  • 58
    • 0037206592 scopus 로고    scopus 로고
    • Chemotherapeutically induced deletion of expanded triplet repeats
    • Hashem,V.I. and Sinden,R.R. (2002) Chemotherapeutically induced deletion of expanded triplet repeats. Mutat. Res., 508 107-119.
    • (2002) Mutat. Res. , vol.508 , pp. 107-119
    • Hashem, V.I.1    Sinden, R.R.2
  • 59
    • 17944404576 scopus 로고    scopus 로고
    • Mutagenic stress modulates the dynamics of CTG repeat instability associated with myotonic dystrophy type 1
    • Pineiro,E., Fernandez-Lopez,L., Gamez,J., Marcos,R., Surralles,J. and Velazquez,A. (2003) Mutagenic stress modulates the dynamics of CTG repeat instability associated with myotonic dystrophy type 1. Nucleic Acids Res., 31, 6733-6740.
    • (2003) Nucleic Acids Res. , vol.31 , pp. 6733-6740
    • Pineiro, E.1    Fernandez-Lopez, L.2    Gamez, J.3    Marcos, R.4    Surralles, J.5    Velazquez, A.6
  • 60
    • 0038044708 scopus 로고    scopus 로고
    • Selectable system for monitoring the instability of CTG/CAG triplet repeats in mammalian cells
    • Gorbunova,V., Seluanov,A., Dion,V., Sandor,Z., Meservy,J.L. and Wilson,J.H. (2003) Selectable system for monitoring the instability of CTG/CAG triplet repeats in mammalian cells. Mol. Cell. Biol., 23, 4485-4493.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 4485-4493
    • Gorbunova, V.1    Seluanov, A.2    Dion, V.3    Sandor, Z.4    Meservy, J.L.5    Wilson, J.H.6
  • 61
    • 0242607211 scopus 로고    scopus 로고
    • Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type 1 disease locus in human cells
    • Yang,Z., Lau,R., Marcadier,J.L., Chitayat,D. and Pearson,C.E. (2003) Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type 1 disease locus in human cells. Am. J. Hum. Genet., 73, 1092-1105.
    • (2003) Am. J. Hum. Genet. , vol.73 , pp. 1092-1105
    • Yang, Z.1    Lau, R.2    Marcadier, J.L.3    Chitayat, D.4    Pearson, C.E.5
  • 62
    • 3042810192 scopus 로고    scopus 로고
    • Chemically induced increases and decreases in the rate of expansion of a CAG•CTG triplet repeat
    • Gomes-Pereira,M. and Monckton,D.G. (2004) Chemically induced increases and decreases in the rate of expansion of a CAG•CTG triplet repeat. Nucleic Acids Res., 32, 2865-2872.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 2865-2872
    • Gomes-Pereira, M.1    Monckton, D.G.2
  • 65
    • 0028873248 scopus 로고
    • Somatic mosaicism, germline expansions, germline reversions and intergenerational reductions in myotonic dystrophy males: Small pool PCR analyses
    • Monckton,D.G., Wong,L.J., Ashizawa,T. and Caskey,C.T. (1995) Somatic mosaicism, germline expansions, germline reversions and intergenerational reductions in myotonic dystrophy males: small pool PCR analyses. Hum. Mol. Genet., 4, 1-8.
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 1-8
    • Monckton, D.G.1    Wong, L.J.2    Ashizawa, T.3    Caskey, C.T.4
  • 66
    • 4544376726 scopus 로고    scopus 로고
    • Analysis of unstable triplet repeats using small-pool polymerase chain reaction
    • Gomes-Pereira,M., Bidichandani,S.I. and Monckton,D.G. (2004) Analysis of unstable triplet repeats using small-pool polymerase chain reaction. Methods Mol. Biol., 277, 61-76.
    • (2004) Methods Mol. Biol. , vol.277 , pp. 61-76
    • Gomes-Pereira, M.1    Bidichandani, S.I.2    Monckton, D.G.3
  • 69
    • 0036844340 scopus 로고    scopus 로고
    • Recombinational repair and restart of damaged replication forks
    • McGlynn,P. and Lloyd,R.G. (2002) Recombinational repair and restart of damaged replication forks. Nature Rev. Mol. Cell Biol., 3, 859-870.
    • (2002) Nature Rev. Mol. Cell Biol. , vol.3 , pp. 859-870
    • McGlynn, P.1    Lloyd, R.G.2
  • 70
    • 0032514711 scopus 로고    scopus 로고
    • Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae
    • Miret,J.J., Pessoa-Brandao,L. and Lahue,R.S. (1998) Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA, 95, 12438-12443.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12438-12443
    • Miret, J.J.1    Pessoa-Brandao, L.2    Lahue, R.S.3
  • 71
    • 4344636050 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats
    • Bhattacharyya,S. and Lahue,R.S. (2004) Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats. Mol. Cell. Biol., 24, 7324-7330.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 7324-7330
    • Bhattacharyya, S.1    Lahue, R.S.2
  • 72
    • 0031965224 scopus 로고    scopus 로고
    • Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation
    • Schweitzer,J.K. and Livingston,D.M. (1998) Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation. Hum. Mol. Genet, 7, 69-74.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 69-74
    • Schweitzer, J.K.1    Livingston, D.M.2
  • 73
    • 0037201423 scopus 로고    scopus 로고
    • Human FEN-1 can process the 5′-flap DNA of CTG/CAG triplet repeat derived from human genetic diseases by length and sequence dependent manner
    • Lee,S. and Park,M.S. (2002) Human FEN-1 can process the 5′-flap DNA of CTG/CAG triplet repeat derived from human genetic diseases by length and sequence dependent manner. Exp. Mol. Med., 34, 313-317.
    • (2002) Exp. Mol. Med. , vol.34 , pp. 313-317
    • Lee, S.1    Park, M.S.2
  • 74
    • 0037133931 scopus 로고    scopus 로고
    • In vitro (CTG)·(CAG) expansions and deletions by human cell extracts
    • Panigrahi,G.B., Cleary,J.D. and Pearson,C.E. (2002) In vitro (CTG)·(CAG) expansions and deletions by human cell extracts. J. Biol. Chem., 277, 13926-13934.
    • (2002) J. Biol. Chem. , vol.277 , pp. 13926-13934
    • Panigrahi, G.B.1    Cleary, J.D.2    Pearson, C.E.3
  • 75
    • 0141780849 scopus 로고    scopus 로고
    • Fidelity of primate cell repair of a double-strand break within a (CTG)·(CAG) tract. Effect of slipped DNA structures
    • Marcadier,J.L. and Pearson,C.E. (2003) Fidelity of primate cell repair of a double-strand break within a (CTG)·(CAG) tract. Effect of slipped DNA structures. J. Biol. Chem., 278, 33848-33856.
    • (2003) J. Biol. Chem. , vol.278 , pp. 33848-33856
    • Marcadier, J.L.1    Pearson, C.E.2
  • 76
    • 0025610156 scopus 로고
    • Delayed appearance of lethal and specific gene mutations in irradiated mammalian cells
    • Little,J.B., Gorgojo,L. and Vetrovs,H. (1990) Delayed appearance of lethal and specific gene mutations in irradiated mammalian cells. Int. J. Radiat. Oncol. Biol. Phys., 19, 1425-1429.
    • (1990) Int. J. Radiat. Oncol. Biol. Phys. , vol.19 , pp. 1425-1429
    • Little, J.B.1    Gorgojo, L.2    Vetrovs, H.3
  • 77
    • 0031673696 scopus 로고    scopus 로고
    • Radiation-induced genomic instability
    • Little,J.B. (1998) Radiation-induced genomic instability. Int. J. Radiat. Biol., 74, 663-671.
    • (1998) Int. J. Radiat. Biol. , vol.74 , pp. 663-671
    • Little, J.B.1
  • 78
    • 0031701077 scopus 로고    scopus 로고
    • Radiation-induced genomic instability in haemopoietic cells
    • Wright,E.G. (1998) Radiation-induced genomic instability in haemopoietic cells. Int. J. Radiat. Biol., 74, 681-687.
    • (1998) Int. J. Radiat. Biol. , vol.74 , pp. 681-687
    • Wright, E.G.1
  • 80
    • 0028846524 scopus 로고
    • Anomalous rapid electrophoretic mobility of DNA containing triplet repeats associated with human disease genes
    • Chastain,P.D., Eichler,E.E., Kang,S., Nelson,D.L., Levene,S.D. and Sinden,R.R. (1995) Anomalous rapid electrophoretic mobility of DNA containing triplet repeats associated with human disease genes. Biochemistry, 34, 16125-16131.
    • (1995) Biochemistry , vol.34 , pp. 16125-16131
    • Chastain, P.D.1    Eichler, E.E.2    Kang, S.3    Nelson, D.L.4    Levene, S.D.5    Sinden, R.R.6
  • 81
    • 0032559372 scopus 로고    scopus 로고
    • CTG repeats associated with human genetic disease are inherently flexible
    • Chastain,P.D. and Sinden,R.R. (1998) CTG repeats associated with human genetic disease are inherently flexible. J. Mol. Biol., 275, 405-411.
    • (1998) J. Mol. Biol. , vol.275 , pp. 405-411
    • Chastain, P.D.1    Sinden, R.R.2
  • 83
    • 0029883805 scopus 로고    scopus 로고
    • Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci
    • Pearson,C.E. and Sinden,R.R. (1996) Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci. Biochemistry, 35, 5041-5053.
    • (1996) Biochemistry , vol.35 , pp. 5041-5053
    • Pearson, C.E.1    Sinden, R.R.2
  • 84
    • 0032102835 scopus 로고    scopus 로고
    • Trinucleotide repeat DNA structures: Dynamic mutations from dynamic DNA
    • Pearson,C.E. and Sinden,R.R. (1998) Trinucleotide repeat DNA structures: dynamic mutations from dynamic DNA. Curr. Opin. Struct. Biol., 8, 321-330.
    • (1998) Curr. Opin. Struct. Biol. , vol.8 , pp. 321-330
    • Pearson, C.E.1    Sinden, R.R.2
  • 86
    • 0029680836 scopus 로고    scopus 로고
    • Targeted mutagenesis mediated by the triple helix formation
    • Glazer,P.M., Wang,G., Havre,P.A. and Gunther,E.J. (1996) Targeted mutagenesis mediated by the triple helix formation. Methods Mol. Biol., 57, 109-118.
    • (1996) Methods Mol. Biol. , vol.57 , pp. 109-118
    • Glazer, P.M.1    Wang, G.2    Havre, P.A.3    Gunther, E.J.4
  • 87
    • 0030902414 scopus 로고    scopus 로고
    • Triplex DNA: Fundamentals, advances, and potential applications for gene therapy
    • Chan,P.P. and Glazer,P.M. (1997) Triplex DNA: fundamentals, advances, and potential applications for gene therapy. J. Mol. Med. 75, 267-282.
    • (1997) J. Mol. Med. , vol.75 , pp. 267-282
    • Chan, P.P.1    Glazer, P.M.2
  • 88
    • 0033989968 scopus 로고    scopus 로고
    • Triplex-directed site-specific genome modification
    • Vasquez,K.M. and Wilson,J.H. (2000) Triplex-directed site-specific genome modification. Methods Mol. Biol., 133, 183-200.
    • (2000) Methods Mol. Biol. , vol.133 , pp. 183-200
    • Vasquez, K.M.1    Wilson, J.H.2
  • 89
    • 0030006487 scopus 로고    scopus 로고
    • Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence
    • Boffa,L.C., Morris,P.L., Carpaneto,E.M., Louissaint,M. and Allfrey,V.G. (1996) Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence. J. Biol. Chem., 271, 13228-13233.
    • (1996) J. Biol. Chem. , vol.271 , pp. 13228-13233
    • Boffa, L.C.1    Morris, P.L.2    Carpaneto, E.M.3    Louissaint, M.4    Allfrey, V.G.5
  • 90
    • 0346752132 scopus 로고    scopus 로고
    • Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis
    • Kennedy,L., Evans,E., Chen,C.M., Craven,L., Detloff,P.J., Ennis,M. and Shelbourne,P.F. (2003) Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis. Hum. Mol. Genet., 12, 3359-3367.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 3359-3367
    • Kennedy, L.1    Evans, E.2    Chen, C.M.3    Craven, L.4    Detloff, P.J.5    Ennis, M.6    Shelbourne, P.F.7
  • 91
    • 0035065524 scopus 로고    scopus 로고
    • Trinucleotide expansion in haploid germ cells by gap repair
    • Kovtun,I.V. and McMurray,C.T. (2001) Trinucleotide expansion in haploid germ cells by gap repair. Nature Genet., 27, 407-411.
    • (2001) Nature Genet. , vol.27 , pp. 407-411
    • Kovtun, I.V.1    McMurray, C.T.2


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