-
2
-
-
0033070196
-
Biological implications of the DNA structures associated with disease-causing triplet repeats
-
Sinden,R.R. (1999) Biological implications of the DNA structures associated with disease-causing triplet repeats. Am. J. Hum. Genet., 64, 346-353.
-
(1999)
Am. J. Hum. Genet.
, vol.64
, pp. 346-353
-
-
Sinden, R.R.1
-
3
-
-
0034640011
-
Fourteen and counting: Unraveling trinucleotide repeat diseases
-
Cummings,C.J. and Zoghbi,H.Y. (2000) Fourteen and counting: unraveling trinucleotide repeat diseases. Hum. Mol. Genet., 9 909-916.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 909-916
-
-
Cummings, C.J.1
Zoghbi, H.Y.2
-
4
-
-
0033862578
-
Insights from mouse models into the molecular basis of neurodegeneration
-
Heintz,N. and Zoghbi,H.Y. (2000) Insights from mouse models into the molecular basis of neurodegeneration. Annu. Rev. Physiol., 62, 779-802.
-
(2000)
Annu. Rev. Physiol.
, vol.62
, pp. 779-802
-
-
Heintz, N.1
Zoghbi, H.Y.2
-
5
-
-
0042759661
-
The contribution of CIS-elements to disease-associated repeat instability: Clinical and experimental evidence
-
Cleary,J.D. and Pearson,C.E. (2003) The contribution of CIS-elements to disease-associated repeat instability: clinical and experimental evidence. Cytogenet. Genome Res., 100, 25-55.
-
(2003)
Cytogenet. Genome Res.
, vol.100
, pp. 25-55
-
-
Cleary, J.D.1
Pearson, C.E.2
-
6
-
-
0002481990
-
Diseases with trinucleotide repeat expansion
-
Appel,S.H. (ed.), IOS Press, Amsterdam
-
Ashizawa,T. and Zoghbi,H.Y. (1997) Diseases with trinucleotide repeat expansion. In Appel,S.H. (ed.), Current Neurology IOS Press, Amsterdam, Vol. 17, pp. 79-135.
-
(1997)
Current Neurology
, vol.17
, pp. 79-135
-
-
Ashizawa, T.1
Zoghbi, H.Y.2
-
7
-
-
0032907359
-
Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients
-
Sato,T., Oyake,M., Nakamura,K., Nakao,K., Fukusima,Y., Onodera,O., Igarashi,S., Takano,H., Kikugawa,K., Ishida,Y. et al. (1999) Transgenic mice harboring a full-length human mutant DRPLA gene exhibit age-dependent intergenerational and somatic instabilities of CAG repeats comparable with those in DRPLA patients. Hum. Mol. Genet., 8, 99-106.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 99-106
-
-
Sato, T.1
Oyake, M.2
Nakamura, K.3
Nakao, K.4
Fukusima, Y.5
Onodera, O.6
Igarashi, S.7
Takano, H.8
Kikugawa, K.9
Ishida, Y.10
-
8
-
-
0031054076
-
Hypermutable myotonic dystrophy CTG repeats in transgenic mice
-
Monckton,D.G., Coolbaugh,M.I., Ashizawa,K.T., Siciliano,M.J. and Caskey,C.T. (1997) Hypermutable myotonic dystrophy CTG repeats in transgenic mice. Nature Genet., 15, 193-196.
-
(1997)
Nature Genet.
, vol.15
, pp. 193-196
-
-
Monckton, D.G.1
Coolbaugh, M.I.2
Ashizawa, K.T.3
Siciliano, M.J.4
Caskey, C.T.5
-
9
-
-
0034639711
-
Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability
-
Fortune,M.T., Vassilopoulos,C., Coolbaugh,M.I., Siciliano,M.J. and Monckton,D.G. (2000) Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability. Hum. Mol. Genet., 9, 439-445.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 439-445
-
-
Fortune, M.T.1
Vassilopoulos, C.2
Coolbaugh, M.I.3
Siciliano, M.J.4
Monckton, D.G.5
-
10
-
-
0031056685
-
Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation
-
Mangiarini,L., Sathasivam,K., Mahal,A., Mott,R., Seller,M. and Bates,G.P. (1997) Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation. Nature Genet., 15, 197-200.
-
(1997)
Nature Genet.
, vol.15
, pp. 197-200
-
-
Mangiarini, L.1
Sathasivam, K.2
Mahal, A.3
Mott, R.4
Seller, M.5
Bates, G.P.6
-
11
-
-
0034194141
-
Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability
-
Seznec,H., Lia-Baldini,A.S., Duros,C., Fouquet,C., Lacroix,C., Hofmann-Radvanyi,H., Junien,C. and Gourdon,G. (2000) Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability. Hum. Mol. Genet., 9, 1185-1194.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1185-1194
-
-
Seznec, H.1
Lia-Baldini, A.S.2
Duros, C.3
Fouquet, C.4
Lacroix, C.5
Hofmann-Radvanyi, H.6
Junien, C.7
Gourdon, G.8
-
12
-
-
0035503214
-
SCA12: An unusual mutation leads to an unusual spinocerebellar ataxia
-
Holmes,S.E., Hearn,E.O., Ross,C.A. and Margolis,R.L. (2001) SCA12: an unusual mutation leads to an unusual spinocerebellar ataxia. Brain Res. Bull., 56, 397-403.
-
(2001)
Brain Res. Bull.
, vol.56
, pp. 397-403
-
-
Holmes, S.E.1
Hearn, E.O.2
Ross, C.A.3
Margolis, R.L.4
-
13
-
-
0028890669
-
Somatic heterogeneity of the CTG repeat in myotonic dystrophy is age and size dependent
-
Wong,L.-J.C., Ashizawa,T., Monckton,D.G., Caskey,C.T. and Richards,C.S. (1995) Somatic heterogeneity of the CTG repeat in myotonic dystrophy is age and size dependent. Am. J. Hum. Genet., 56, 114-122.
-
(1995)
Am. J. Hum. Genet.
, vol.56
, pp. 114-122
-
-
Wong, L.-J.C.1
Ashizawa, T.2
Monckton, D.G.3
Caskey, C.T.4
Richards, C.S.5
-
14
-
-
0031984489
-
Progression of somatic CTG repeat length heterogeneity in the blood cells of myotonic dystrophy patients
-
Martorell,L., Monckton,D.G., Gamez,J., Johnson,K.J., Gich,I., de Munain,A.L. and Baiget,M. (1998) Progression of somatic CTG repeat length heterogeneity in the blood cells of myotonic dystrophy patients. Hum. Mol. Genet., 7, 307-312.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 307-312
-
-
Martorell, L.1
Monckton, D.G.2
Gamez, J.3
Johnson, K.J.4
Gich, I.5
de Munain, A.L.6
Baiget, M.7
-
15
-
-
0344531040
-
Transgenic mouse models for myotonic dystrophy type 1 (DM1)
-
Wansink,D.G. and Wieringa,B. (2003) Transgenic mouse models for myotonic dystrophy type 1 (DM1). Cytogenet. Genome Res., 100 230-242.
-
(2003)
Cytogenet. Genome Res.
, vol.100
, pp. 230-242
-
-
Wansink, D.G.1
Wieringa, B.2
-
16
-
-
0035903189
-
Involvement of the nucleotide excision repair protein UvrA in instability of (CAG)·(CTG) repeat sequences in E.coli
-
Oussatcheva,E.A., Hashem,V.I., Zou,Y., Sinden,R.R. and Potaman,V.N. (2001) Involvement of the nucleotide excision repair protein UvrA in instability of (CAG)·(CTG) repeat sequences in E.coli. J. Biol. Chem., 276, 30878-30884.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30878-30884
-
-
Oussatcheva, E.A.1
Hashem, V.I.2
Zou, Y.3
Sinden, R.R.4
Potaman, V.N.5
-
17
-
-
0037157222
-
Genetic assays for measuring rates of (CAG)·(CTG) repeat instability in Escherichia coli
-
Hashem,V.I., Rosche,W.A. and Sinden,R.R. (2002) Genetic assays for measuring rates of (CAG)·(CTG) repeat instability in Escherichia coli. Mutat. Res., 502, 25-37.
-
(2002)
Mutat. Res.
, vol.502
, pp. 25-37
-
-
Hashem, V.I.1
Rosche, W.A.2
Sinden, R.R.3
-
18
-
-
0033551777
-
Genetic instabilities in (CTG)·(CAG) repeats occur by recombination
-
Jakupciak,J.P. and Wells,R.D. (1999) Genetic instabilities in (CTG)·(CAG) repeats occur by recombination. J. Biol. Chem., 274 23468-23479.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23468-23479
-
-
Jakupciak, J.P.1
Wells, R.D.2
-
19
-
-
0032102835
-
Trinucleotide repeat DNA structures: Dynamic mutations from dynamic DNA
-
Pearson,C.E. and Sinden,R.R. (1998) Trinucleotide repeat DNA structures: Dynamic mutations from dynamic DNA. Curr. Opin. Struct. Biol., 8, 321-330.
-
(1998)
Curr. Opin. Struct. Biol.
, vol.8
, pp. 321-330
-
-
Pearson, C.E.1
Sinden, R.R.2
-
20
-
-
0030737538
-
Trinucleotide repeats associated with human disease
-
Mitas,M. (1997) Trinucleotide repeats associated with human disease. Nucleic Acids Res., 25, 2245-2253.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 2245-2253
-
-
Mitas, M.1
-
21
-
-
0032498265
-
Secondary structures in d(CGG) and d(CCG) repeat tracts
-
Darlow,J.M. and Leach,D.R.F. (1998) Secondary structures in d(CGG) and d(CCG) repeat tracts. J. Mol. Biol., 275, 3-16.
-
(1998)
J. Mol. Biol.
, vol.275
, pp. 3-16
-
-
Darlow, J.M.1
Leach, D.R.F.2
-
22
-
-
0000486352
-
Slipped strand DNA, dynamic mutations, and human disease
-
Wells,R.D. and Warren,S.T. (eds.), Academic Press, San Diego, CA
-
Pearson,C.E. and Sinden,R.R. (1998) Slipped strand DNA, dynamic mutations, and human disease. In Wells,R.D. and Warren,S.T. (eds.), Genetic Instabilities and Hereditary Neurological Disorders Academic Press, San Diego, CA, pp. 585-621.
-
(1998)
Genetic Instabilities and Hereditary Neurological Disorders
, pp. 585-621
-
-
Pearson, C.E.1
Sinden, R.R.2
-
23
-
-
0028874391
-
CGG repeats associated with DNA instability and chromosome fragility form structures that block DNA synthesis in vitro
-
Usdin,K. and Woodford,K.J. (1995) CGG repeats associated with DNA instability and chromosome fragility form structures that block DNA synthesis in vitro. Nucleic Acids Res., 23, 4202-4209.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 4202-4209
-
-
Usdin, K.1
Woodford, K.J.2
-
24
-
-
0028362201
-
The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure
-
Fry,M. and Loeb,L.A. (1994) The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure. Proc. Natl Acad. Sci. USA, 91, 4950-4954.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4950-4954
-
-
Fry, M.1
Loeb, L.A.2
-
25
-
-
0031941447
-
The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure
-
Bidichandani,S.I., Ashizawa,T. and Patel,P.I. (1998) The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure. Am. J. Hum. Genet., 62, 111-121.
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 111-121
-
-
Bidichandani, S.I.1
Ashizawa, T.2
Patel, P.I.3
-
26
-
-
0033525103
-
The high-resolution structure of the triplex formed by the GAA/TTC triplet repeat associated with Friedreich's ataxia
-
Mariappan,S.V., Catasti,P., Silks,L.A., III, Bradbury,E.M. and Gupta,G. (1999) The high-resolution structure of the triplex formed by the GAA/TTC triplet repeat associated with Friedreich's ataxia. J. Mol. Biol., 285, 2035-2052.
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 2035-2052
-
-
Mariappan, S.V.1
Catasti, P.2
Silks III, L.A.3
Bradbury, E.M.4
Gupta, G.5
-
27
-
-
0034660695
-
The GAA•TTC triplet repeat expanded in Friedreich's ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner
-
Grabczyk,E. and Usdin,K. (2000) The GAA•TTC triplet repeat expanded in Friedreich's ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner. Nucleic Acids Res., 28, 2815-2822.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2815-2822
-
-
Grabczyk, E.1
Usdin, K.2
-
28
-
-
0034612992
-
Unexpected formation of parallel duplex in GAA and TTC trinucleotide repeats of Friedreich's ataxia
-
LeProust,E.M., Pearson,C.E., Sinden,R.R. and Gao,X. (2000) Unexpected formation of parallel duplex in GAA and TTC trinucleotide repeats of Friedreich's ataxia. J. Mol. Biol., 302, 1063-1080.
-
(2000)
J. Mol. Biol.
, vol.302
, pp. 1063-1080
-
-
LeProust, E.M.1
Pearson, C.E.2
Sinden, R.R.3
Gao, X.4
-
29
-
-
0033120042
-
Sticky DNA: Self-association properties of long GAA · TTC repeats in R · R · Y triplex structures from Friedreich's ataxia
-
Sakamoto,N., Chastain,P.D., Parniewski,P., Ohshima,K., Pandolfo,M., Griffith,J.D. and Wells,R.D. (1999) Sticky DNA: self-association properties of long GAA · TTC repeats in R · R · Y triplex structures from Friedreich's ataxia. Mol. Cell, 3, 465-475.
-
(1999)
Mol. Cell
, vol.3
, pp. 465-475
-
-
Sakamoto, N.1
Chastain, P.D.2
Parniewski, P.3
Ohshima, K.4
Pandolfo, M.5
Griffith, J.D.6
Wells, R.D.7
-
30
-
-
2342627878
-
n repeats at neutral pH
-
n repeats at neutral pH Nucleic Acids Res., 32 1224-1231.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 1224-1231
-
-
Potaman, V.N.1
Oussatcheva, E.A.2
Lyubchenko, Y.L.3
Shlyakhtenko, L.S.4
Bidichandani, S.I.5
Ashizawa, T.6
Sinden, R.R.7
-
31
-
-
0032486276
-
Inhibitory effects of expanded GAA·TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo
-
Ohshima,K., Montermini,L., Wells,R.D. and Pandolfo,M. (1998) Inhibitory effects of expanded GAA·TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo. J. Biol. Chem., 273, 14588-14595.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14588-14595
-
-
Ohshima, K.1
Montermini, L.2
Wells, R.D.3
Pandolfo, M.4
-
32
-
-
0029950726
-
Cloning, characterization, and properties of seven triplet repeat DNA sequences
-
Ohshima,K., Kang,S., Larson,J.E. and Wells,R.D. (1996) Cloning, characterization, and properties of seven triplet repeat DNA sequences. J. Biol. Chem., 271, 16773-16783.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16773-16783
-
-
Ohshima, K.1
Kang, S.2
Larson, J.E.3
Wells, R.D.4
-
33
-
-
0037470576
-
n repeats
-
n repeats. J. Mol Biol., 326, 1095-1111.
-
(2003)
J. Mol. Biol.
, vol.326
, pp. 1095-1111
-
-
Potaman, V.N.1
Bissler, J.J.2
Hashem, V.I.3
Oussatcheva, E.A.4
Lu, L.5
Shlyakhtenko, L.S.6
Lyubchenko, Y.L.7
Matsuura, T.8
Ashizawa, T.9
Leffak, M.10
-
34
-
-
0029035379
-
Expansion and deletion of CTG triplet repeats from human disease genes are determined by the direction of replication in E.coli
-
Kang,S., Jaworski,A., Ohshima,K. and Wells,R.D. (1995) Expansion and deletion of CTG triplet repeats from human disease genes are determined by the direction of replication in E.coli. Nature Genet., 10, 213-218.
-
(1995)
Nature Genet.
, vol.10
, pp. 213-218
-
-
Kang, S.1
Jaworski, A.2
Ohshima, K.3
Wells, R.D.4
-
35
-
-
0028820372
-
The effects of trinucleotide repeats found in human inherited disorders on palindrome inviability in Escherichia coli suggest hairpin folding preferences in vivo
-
Darlow,J.M. and Leach,D.R.F. (1995) The effects of trinucleotide repeats found in human inherited disorders on palindrome inviability in Escherichia coli suggest hairpin folding preferences in vivo. Genetics, 141, 825-832.
-
(1995)
Genetics
, vol.141
, pp. 825-832
-
-
Darlow, J.M.1
Leach, D.R.F.2
-
36
-
-
0032498304
-
Evidence for two preferred hairpin folding patterns in d(CGG)•d(CCG) repeat tracts in vivo
-
Darlow,J.M. and Leach,D.F. (1998) Evidence for two preferred hairpin folding patterns in d(CGG)•d(CCG) repeat tracts in vivo. J. Mol. Biol., 275, 17-23.
-
(1998)
J. Mol. Biol.
, vol.275
, pp. 17-23
-
-
Darlow, J.M.1
Leach, D.F.2
-
37
-
-
0030895078
-
Stability of a CTG/CAG trinucleotide repeat in yeast is dependent on its orientation in the genome
-
Freudenreich,C.H., Stavenhagen,J.B. and Zakian,V.A. (1997) Stability of a CTG/CAG trinucleotide repeat in yeast is dependent on its orientation in the genome. Mol. Cell. Biol., 17, 2090-2098.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2090-2098
-
-
Freudenreich, C.H.1
Stavenhagen, J.B.2
Zakian, V.A.3
-
38
-
-
0036578758
-
Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells
-
Cleary,J.D., Nichol,K., Wang,Y.H. and Pearson,C.E. (2002) Evidence of cis-acting factors in replication-mediated trinucleotide repeat instability in primate cells. Nature Genet., 31, 37-46.
-
(2002)
Nature Genet.
, vol.31
, pp. 37-46
-
-
Cleary, J.D.1
Nichol, K.2
Wang, Y.H.3
Pearson, C.E.4
-
39
-
-
0033895728
-
The impact of lagging strand replication mutations on the stability of CAG repeat tracts in yeast
-
Ireland,M.J., Reinke,S.S. and Livingston,D.M. (2000) The impact of lagging strand replication mutations on the stability of CAG repeat tracts in yeast. Genetics, 155, 1657-1665.
-
(2000)
Genetics
, vol.155
, pp. 1657-1665
-
-
Ireland, M.J.1
Reinke, S.S.2
Livingston, D.M.3
-
40
-
-
0032779262
-
The effect of DNA replication mutations on CAG tract stability in yeast
-
Schweitzer,J.K. and Livingston,D.M. (1999) The effect of DNA replication mutations on CAG tract stability in yeast. Genetics, 152, 953-963.
-
(1999)
Genetics
, vol.152
, pp. 953-963
-
-
Schweitzer, J.K.1
Livingston, D.M.2
-
41
-
-
0026419949
-
Preferential DNA secondary structure mutagenesis in the lagging strand of replication in E.coli
-
Trinh,T.Q. and Sinden,R.R. (1991) Preferential DNA secondary structure mutagenesis in the lagging strand of replication in E.coli. Nature, 352, 544-547.
-
(1991)
Nature
, vol.352
, pp. 544-547
-
-
Trinh, T.Q.1
Sinden, R.R.2
-
42
-
-
0026352538
-
On the deletion of inverted repeated DNA in Escherichia coli: Effects of length, thermal stability, and cruciform formation in vivo
-
Sinden,R.R., Zheng,G., Brankamp,R.G. and Allen,K.N. (1991) On the deletion of inverted repeated DNA in Escherichia coli: Effects of length, thermal stability, and cruciform formation in vivo. Genetics, 129, 991-1005.
-
(1991)
Genetics
, vol.129
, pp. 991-1005
-
-
Sinden, R.R.1
Zheng, G.2
Brankamp, R.G.3
Allen, K.N.4
-
44
-
-
0037315530
-
Replication and expansion of trinucleotide repeats in yeast
-
Pelletier,R., Krasilnikova,M.M., Samadashwily,G.M., Lahue,R. and Mirkin, S.M. (2003) Replication and expansion of trinucleotide repeats in yeast. Mol. Cell. Biol., 23, 1349-1357.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 1349-1357
-
-
Pelletier, R.1
Krasilnikova, M.M.2
Samadashwily, G.M.3
Lahue, R.4
Mirkin, S.M.5
-
46
-
-
0030725454
-
Trinucleotide repeats affect DNA replication in vivo
-
Samadashwily,G.M., Raca,G. and Mirkin,S.M. (1997) Trinucleotide repeats affect DNA replication in vivo. Nature Genet. 17, 298-304.
-
(1997)
Nature Genet.
, vol.17
, pp. 298-304
-
-
Samadashwily, G.M.1
Raca, G.2
Mirkin, S.M.3
-
47
-
-
0142027842
-
Mutations in yeast replication proteins that increase CAG/CTG expansions also increase repeat fragility
-
Callahan,J.L., Andrews,K.J., Zakian,V.A. and Freudenreich,C.H. (2003) Mutations in yeast replication proteins that increase CAG/CTG expansions also increase repeat fragility. Mol. Cell. Biol., 23, 7849-7860.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7849-7860
-
-
Callahan, J.L.1
Andrews, K.J.2
Zakian, V.A.3
Freudenreich, C.H.4
-
48
-
-
0032488872
-
Expansion and length-dependent fragility of CTG repeats in yeast
-
Freudenreich,C.H., Kantrow,S.M. and Zakian,V.A. (1998) Expansion and length-dependent fragility of CTG repeats in yeast. Science, 279, 853-856.
-
(1998)
Science
, vol.279
, pp. 853-856
-
-
Freudenreich, C.H.1
Kantrow, S.M.2
Zakian, V.A.3
-
49
-
-
13444253858
-
Structure-forming CAG/CTG repeat sequences are sensitive to breakage in the absence of Mrc1 checkpoint function and S-phase checkpoint signaling: Implications for trinucleotide repeat expansion diseases
-
Freudenreich,C.H. and Lahiri,M. (2004) Structure-forming CAG/CTG repeat sequences are sensitive to breakage in the absence of Mrc1 checkpoint function and S-phase checkpoint signaling: implications for trinucleotide repeat expansion diseases. Cell Cycle, 3.
-
(2004)
Cell Cycle
, vol.3
-
-
Freudenreich, C.H.1
Lahiri, M.2
-
50
-
-
3242658268
-
Expanded CAG repeats activate the DNA damage checkpoint pathway
-
Lahiri,M., Gustafson,T.L., Majors,E.R. and Freudenreich,C.H. (2004) Expanded CAG repeats activate the DNA damage checkpoint pathway. Mol. Cell, 15, 287-293.
-
(2004)
Mol. Cell
, vol.15
, pp. 287-293
-
-
Lahiri, M.1
Gustafson, T.L.2
Majors, E.R.3
Freudenreich, C.H.4
-
51
-
-
1942422156
-
Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability
-
Liu,Y., Zhang,H., Veeraraghavan,J., Bambara,R.A. and Freudenreich,C.H. (2004) Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability. Mol. Cell. Biol., 24, 4049-4064.
-
(2004)
Mol. Cell Biol.
, vol.24
, pp. 4049-4064
-
-
Liu, Y.1
Zhang, H.2
Veeraraghavan, J.3
Bambara, R.A.4
Freudenreich, C.H.5
-
52
-
-
0035052982
-
Cis-elements governing trinucleotide repeat instability in Saccharomyces cerevisiae
-
Rolfsmeier,M.L., Dixon,M.J., Pessoa-Brandao,L., Pelletier,R., Miret,J.J. and Lahue,R.S. (2001) Cis-elements governing trinucleotide repeat instability in Saccharomyces cerevisiae. Genetics 157, 1569-1579.
-
(2001)
Genetics
, vol.157
, pp. 1569-1579
-
-
Rolfsmeier, M.L.1
Dixon, M.J.2
Pessoa-Brandao, L.3
Pelletier, R.4
Miret, J.J.5
Lahue, R.S.6
-
53
-
-
0842287698
-
DNA double-strand break repair by homologous recombination
-
Dudas,A. and Chovanec,M. (2004) DNA double-strand break repair by homologous recombination. Mutat. Res., 566, 131-167.
-
(2004)
Mutat. Res.
, vol.566
, pp. 131-167
-
-
Dudas, A.1
Chovanec, M.2
-
54
-
-
0036336673
-
DNA double-strand break repair by homologous recombination
-
van den Bosch,M., Lohman,P.H. and Pastink,A. (2002) DNA double-strand break repair by homologous recombination. Biol. Chem. 383, 873-892.
-
(2002)
Biol. Chem.
, vol.383
, pp. 873-892
-
-
van den Bosch, M.1
Lohman, P.H.2
Pastink, A.3
-
55
-
-
0036900120
-
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair
-
table
-
Symington,L.S. (2002) Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair. Microbiol. Mol. Biol. Rev., 66, 630-70, table.
-
(2002)
Microbiol. Mol. Biol. Rev.
, vol.66
, pp. 630-670
-
-
Symington, L.S.1
-
56
-
-
0942268167
-
Repair of DNA double strand breaks by non-homologous end joining
-
Lees-Miller,S.P. and Meek,K. (2003) Repair of DNA double strand breaks by non-homologous end joining. Biochimie, 85, 1161-1173.
-
(2003)
Biochimie
, vol.85
, pp. 1161-1173
-
-
Lees-Miller, S.P.1
Meek, K.2
-
57
-
-
0004228157
-
-
ASM Press, Washington, DC, 288
-
Friedberg,E.C., Walker,G.C. and Siede,W. (1995) DNA Repair and Mutagenesis. ASM Press, Washington, DC, pp. 213-214, 288.
-
(1995)
DNA Repair and Mutagenesis
, pp. 213-214
-
-
Friedberg, E.C.1
Walker, G.C.2
Siede, W.3
-
58
-
-
0037206592
-
Chemotherapeutically induced deletion of expanded triplet repeats
-
Hashem,V.I. and Sinden,R.R. (2002) Chemotherapeutically induced deletion of expanded triplet repeats. Mutat. Res., 508 107-119.
-
(2002)
Mutat. Res.
, vol.508
, pp. 107-119
-
-
Hashem, V.I.1
Sinden, R.R.2
-
59
-
-
17944404576
-
Mutagenic stress modulates the dynamics of CTG repeat instability associated with myotonic dystrophy type 1
-
Pineiro,E., Fernandez-Lopez,L., Gamez,J., Marcos,R., Surralles,J. and Velazquez,A. (2003) Mutagenic stress modulates the dynamics of CTG repeat instability associated with myotonic dystrophy type 1. Nucleic Acids Res., 31, 6733-6740.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 6733-6740
-
-
Pineiro, E.1
Fernandez-Lopez, L.2
Gamez, J.3
Marcos, R.4
Surralles, J.5
Velazquez, A.6
-
60
-
-
0038044708
-
Selectable system for monitoring the instability of CTG/CAG triplet repeats in mammalian cells
-
Gorbunova,V., Seluanov,A., Dion,V., Sandor,Z., Meservy,J.L. and Wilson,J.H. (2003) Selectable system for monitoring the instability of CTG/CAG triplet repeats in mammalian cells. Mol. Cell. Biol., 23, 4485-4493.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 4485-4493
-
-
Gorbunova, V.1
Seluanov, A.2
Dion, V.3
Sandor, Z.4
Meservy, J.L.5
Wilson, J.H.6
-
61
-
-
0242607211
-
Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type 1 disease locus in human cells
-
Yang,Z., Lau,R., Marcadier,J.L., Chitayat,D. and Pearson,C.E. (2003) Replication inhibitors modulate instability of an expanded trinucleotide repeat at the myotonic dystrophy type 1 disease locus in human cells. Am. J. Hum. Genet., 73, 1092-1105.
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 1092-1105
-
-
Yang, Z.1
Lau, R.2
Marcadier, J.L.3
Chitayat, D.4
Pearson, C.E.5
-
62
-
-
3042810192
-
Chemically induced increases and decreases in the rate of expansion of a CAG•CTG triplet repeat
-
Gomes-Pereira,M. and Monckton,D.G. (2004) Chemically induced increases and decreases in the rate of expansion of a CAG•CTG triplet repeat. Nucleic Acids Res., 32, 2865-2872.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 2865-2872
-
-
Gomes-Pereira, M.1
Monckton, D.G.2
-
64
-
-
0035311419
-
'Mitotic drive' of expanded CTG repeats in myotonic dystrophy type 1 (DM1)
-
Khajavi,M., Tari,A.M., Patel,N.B., Tsuji,K., Siwak,D.R., Meistrich,M.L., Terry,N.H. and Ashizawa,T. (2001) 'Mitotic drive' of expanded CTG repeats in myotonic dystrophy type 1 (DM1). Hum. Mol. Genet., 10, 855-863.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 855-863
-
-
Khajavi, M.1
Tari, A.M.2
Patel, N.B.3
Tsuji, K.4
Siwak, D.R.5
Meistrich, M.L.6
Terry, N.H.7
Ashizawa, T.8
-
65
-
-
0028873248
-
Somatic mosaicism, germline expansions, germline reversions and intergenerational reductions in myotonic dystrophy males: Small pool PCR analyses
-
Monckton,D.G., Wong,L.J., Ashizawa,T. and Caskey,C.T. (1995) Somatic mosaicism, germline expansions, germline reversions and intergenerational reductions in myotonic dystrophy males: small pool PCR analyses. Hum. Mol. Genet., 4, 1-8.
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 1-8
-
-
Monckton, D.G.1
Wong, L.J.2
Ashizawa, T.3
Caskey, C.T.4
-
66
-
-
4544376726
-
Analysis of unstable triplet repeats using small-pool polymerase chain reaction
-
Gomes-Pereira,M., Bidichandani,S.I. and Monckton,D.G. (2004) Analysis of unstable triplet repeats using small-pool polymerase chain reaction. Methods Mol. Biol., 277, 61-76.
-
(2004)
Methods Mol. Biol.
, vol.277
, pp. 61-76
-
-
Gomes-Pereira, M.1
Bidichandani, S.I.2
Monckton, D.G.3
-
67
-
-
0842347339
-
Germline mutational dynamics in myotonic dystrophy type 1 males: Allele length and age effects
-
Martorell,L., Gamez,J., Cayuela,M.L., Gould,F.K., McAbney,J.P., Ashizawa,T., Monckton,D.G. and Baiget,M. (2004) Germline mutational dynamics in myotonic dystrophy type 1 males: allele length and age effects. Neurology, 62, 269-274.
-
(2004)
Neurology
, vol.62
, pp. 269-274
-
-
Martorell, L.1
Gamez, J.2
Cayuela, M.L.3
Gould, F.K.4
McAbney, J.P.5
Ashizawa, T.6
Monckton, D.G.7
Baiget, M.8
-
68
-
-
0029762671
-
Single-stranded DNA-binding protein enhances the stability of CTG triplet repeats in Escherichia coli
-
Rosche,W.A., Jaworski,A., Kang,S., Kramer,S.F., Larson,J.E., Geidroc,D.P., Wells,R.D. and Sinden,R.R. (1996) Single-stranded DNA-binding protein enhances the stability of CTG triplet repeats in Escherichia coli. J. Bacteriol., 178, 5042-5044.
-
(1996)
J. Bacteriol.
, vol.178
, pp. 5042-5044
-
-
Rosche, W.A.1
Jaworski, A.2
Kang, S.3
Kramer, S.F.4
Larson, J.E.5
Geidroc, D.P.6
Wells, R.D.7
Sinden, R.R.8
-
69
-
-
0036844340
-
Recombinational repair and restart of damaged replication forks
-
McGlynn,P. and Lloyd,R.G. (2002) Recombinational repair and restart of damaged replication forks. Nature Rev. Mol. Cell Biol., 3, 859-870.
-
(2002)
Nature Rev. Mol. Cell Biol.
, vol.3
, pp. 859-870
-
-
McGlynn, P.1
Lloyd, R.G.2
-
70
-
-
0032514711
-
Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae
-
Miret,J.J., Pessoa-Brandao,L. and Lahue,R.S. (1998) Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA, 95, 12438-12443.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12438-12443
-
-
Miret, J.J.1
Pessoa-Brandao, L.2
Lahue, R.S.3
-
71
-
-
4344636050
-
Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats
-
Bhattacharyya,S. and Lahue,R.S. (2004) Saccharomyces cerevisiae Srs2 DNA helicase selectively blocks expansions of trinucleotide repeats. Mol. Cell. Biol., 24, 7324-7330.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7324-7330
-
-
Bhattacharyya, S.1
Lahue, R.S.2
-
72
-
-
0031965224
-
Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation
-
Schweitzer,J.K. and Livingston,D.M. (1998) Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation. Hum. Mol. Genet, 7, 69-74.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 69-74
-
-
Schweitzer, J.K.1
Livingston, D.M.2
-
73
-
-
0037201423
-
Human FEN-1 can process the 5′-flap DNA of CTG/CAG triplet repeat derived from human genetic diseases by length and sequence dependent manner
-
Lee,S. and Park,M.S. (2002) Human FEN-1 can process the 5′-flap DNA of CTG/CAG triplet repeat derived from human genetic diseases by length and sequence dependent manner. Exp. Mol. Med., 34, 313-317.
-
(2002)
Exp. Mol. Med.
, vol.34
, pp. 313-317
-
-
Lee, S.1
Park, M.S.2
-
74
-
-
0037133931
-
In vitro (CTG)·(CAG) expansions and deletions by human cell extracts
-
Panigrahi,G.B., Cleary,J.D. and Pearson,C.E. (2002) In vitro (CTG)·(CAG) expansions and deletions by human cell extracts. J. Biol. Chem., 277, 13926-13934.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 13926-13934
-
-
Panigrahi, G.B.1
Cleary, J.D.2
Pearson, C.E.3
-
75
-
-
0141780849
-
Fidelity of primate cell repair of a double-strand break within a (CTG)·(CAG) tract. Effect of slipped DNA structures
-
Marcadier,J.L. and Pearson,C.E. (2003) Fidelity of primate cell repair of a double-strand break within a (CTG)·(CAG) tract. Effect of slipped DNA structures. J. Biol. Chem., 278, 33848-33856.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33848-33856
-
-
Marcadier, J.L.1
Pearson, C.E.2
-
76
-
-
0025610156
-
Delayed appearance of lethal and specific gene mutations in irradiated mammalian cells
-
Little,J.B., Gorgojo,L. and Vetrovs,H. (1990) Delayed appearance of lethal and specific gene mutations in irradiated mammalian cells. Int. J. Radiat. Oncol. Biol. Phys., 19, 1425-1429.
-
(1990)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.19
, pp. 1425-1429
-
-
Little, J.B.1
Gorgojo, L.2
Vetrovs, H.3
-
77
-
-
0031673696
-
Radiation-induced genomic instability
-
Little,J.B. (1998) Radiation-induced genomic instability. Int. J. Radiat. Biol., 74, 663-671.
-
(1998)
Int. J. Radiat. Biol.
, vol.74
, pp. 663-671
-
-
Little, J.B.1
-
78
-
-
0031701077
-
Radiation-induced genomic instability in haemopoietic cells
-
Wright,E.G. (1998) Radiation-induced genomic instability in haemopoietic cells. Int. J. Radiat. Biol., 74, 681-687.
-
(1998)
Int. J. Radiat. Biol.
, vol.74
, pp. 681-687
-
-
Wright, E.G.1
-
79
-
-
0342313475
-
Transgenerational mutation by radiation
-
Dubrova,Y.E., Plumb,M., Gutierrez,B., Boulton,E. and Jeffreys,A.J. (2000) Transgenerational mutation by radiation. Nature 405, 37.
-
(2000)
Nature
, vol.405
, pp. 37
-
-
Dubrova, Y.E.1
Plumb, M.2
Gutierrez, B.3
Boulton, E.4
Jeffreys, A.J.5
-
80
-
-
0028846524
-
Anomalous rapid electrophoretic mobility of DNA containing triplet repeats associated with human disease genes
-
Chastain,P.D., Eichler,E.E., Kang,S., Nelson,D.L., Levene,S.D. and Sinden,R.R. (1995) Anomalous rapid electrophoretic mobility of DNA containing triplet repeats associated with human disease genes. Biochemistry, 34, 16125-16131.
-
(1995)
Biochemistry
, vol.34
, pp. 16125-16131
-
-
Chastain, P.D.1
Eichler, E.E.2
Kang, S.3
Nelson, D.L.4
Levene, S.D.5
Sinden, R.R.6
-
81
-
-
0032559372
-
CTG repeats associated with human genetic disease are inherently flexible
-
Chastain,P.D. and Sinden,R.R. (1998) CTG repeats associated with human genetic disease are inherently flexible. J. Mol. Biol., 275, 405-411.
-
(1998)
J. Mol. Biol.
, vol.275
, pp. 405-411
-
-
Chastain, P.D.1
Sinden, R.R.2
-
82
-
-
0030839912
-
Flexible DNA - Genetically unstable CTG•CAG and CGG•CCG from human hereditary neuromuscular disease genes
-
Bacolla,A., Gellibolian,R., Shimizu,M., Amirhaeri,S., Kang,S., Ohshima,K., Larson,J.E., Harvey,S.C., Stollar,B.D. and Wells,R.D. (1997) Flexible DNA - genetically unstable CTG•CAG and CGG•CCG from human hereditary neuromuscular disease genes. J.Biol.Chem., 272, 16783-16792.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16783-16792
-
-
Bacolla, A.1
Gellibolian, R.2
Shimizu, M.3
Amirhaeri, S.4
Kang, S.5
Ohshima, K.6
Larson, J.E.7
Harvey, S.C.8
Stollar, B.D.9
Wells, R.D.10
-
83
-
-
0029883805
-
Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci
-
Pearson,C.E. and Sinden,R.R. (1996) Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci. Biochemistry, 35, 5041-5053.
-
(1996)
Biochemistry
, vol.35
, pp. 5041-5053
-
-
Pearson, C.E.1
Sinden, R.R.2
-
84
-
-
0032102835
-
Trinucleotide repeat DNA structures: Dynamic mutations from dynamic DNA
-
Pearson,C.E. and Sinden,R.R. (1998) Trinucleotide repeat DNA structures: dynamic mutations from dynamic DNA. Curr. Opin. Struct. Biol., 8, 321-330.
-
(1998)
Curr. Opin. Struct. Biol.
, vol.8
, pp. 321-330
-
-
Pearson, C.E.1
Sinden, R.R.2
-
86
-
-
0029680836
-
Targeted mutagenesis mediated by the triple helix formation
-
Glazer,P.M., Wang,G., Havre,P.A. and Gunther,E.J. (1996) Targeted mutagenesis mediated by the triple helix formation. Methods Mol. Biol., 57, 109-118.
-
(1996)
Methods Mol. Biol.
, vol.57
, pp. 109-118
-
-
Glazer, P.M.1
Wang, G.2
Havre, P.A.3
Gunther, E.J.4
-
87
-
-
0030902414
-
Triplex DNA: Fundamentals, advances, and potential applications for gene therapy
-
Chan,P.P. and Glazer,P.M. (1997) Triplex DNA: fundamentals, advances, and potential applications for gene therapy. J. Mol. Med. 75, 267-282.
-
(1997)
J. Mol. Med.
, vol.75
, pp. 267-282
-
-
Chan, P.P.1
Glazer, P.M.2
-
88
-
-
0033989968
-
Triplex-directed site-specific genome modification
-
Vasquez,K.M. and Wilson,J.H. (2000) Triplex-directed site-specific genome modification. Methods Mol. Biol., 133, 183-200.
-
(2000)
Methods Mol. Biol.
, vol.133
, pp. 183-200
-
-
Vasquez, K.M.1
Wilson, J.H.2
-
89
-
-
0030006487
-
Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence
-
Boffa,L.C., Morris,P.L., Carpaneto,E.M., Louissaint,M. and Allfrey,V.G. (1996) Invasion of the CAG triplet repeats by a complementary peptide nucleic acid inhibits transcription of the androgen receptor and TATA-binding protein genes and correlates with refolding of an active nucleosome containing a unique AR gene sequence. J. Biol. Chem., 271, 13228-13233.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13228-13233
-
-
Boffa, L.C.1
Morris, P.L.2
Carpaneto, E.M.3
Louissaint, M.4
Allfrey, V.G.5
-
90
-
-
0346752132
-
Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis
-
Kennedy,L., Evans,E., Chen,C.M., Craven,L., Detloff,P.J., Ennis,M. and Shelbourne,P.F. (2003) Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis. Hum. Mol. Genet., 12, 3359-3367.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 3359-3367
-
-
Kennedy, L.1
Evans, E.2
Chen, C.M.3
Craven, L.4
Detloff, P.J.5
Ennis, M.6
Shelbourne, P.F.7
-
91
-
-
0035065524
-
Trinucleotide expansion in haploid germ cells by gap repair
-
Kovtun,I.V. and McMurray,C.T. (2001) Trinucleotide expansion in haploid germ cells by gap repair. Nature Genet., 27, 407-411.
-
(2001)
Nature Genet.
, vol.27
, pp. 407-411
-
-
Kovtun, I.V.1
McMurray, C.T.2
|