-
1
-
-
0024317904
-
Prevalence of Alzheimer's disease in a community population of older people
-
Evans DA, Funkenstein HH, Albert MS, Scherr PA, Cook NR, Chown MJ, Hebert LE, Hennekens CH, Taylor JO: Prevalence of Alzheimer's disease in a community population of older people. JAMA 1989, 262:2551-2556
-
(1989)
JAMA
, vol.262
, pp. 2551-2556
-
-
Evans, D.A.1
Funkenstein, H.H.2
Albert, M.S.3
Scherr, P.A.4
Cook, N.R.5
Chown, M.J.6
Hebert, L.E.7
Hennekens, C.H.8
Taylor, J.O.9
-
2
-
-
0028169925
-
Visualization of Aβ 42(43) and Aβ 40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ 42(43)
-
Iwatsubo T, Odaka A, Suzuki N, Mizusawa H, Nukina N, Ihara Y: Visualization of Aβ 42(43) and Aβ 40 in senile plaques with end-specific Aβ monoclonals: evidence that an initially deposited species is Aβ 42(43). Neuron 1994, 13:45-53
-
(1994)
Neuron
, vol.13
, pp. 45-53
-
-
Iwatsubo, T.1
Odaka, A.2
Suzuki, N.3
Mizusawa, H.4
Nukina, N.5
Ihara, Y.6
-
3
-
-
0035950225
-
Clearing the brain's amyloid cobwebs
-
Selkoe DJ: Clearing the brain's amyloid cobwebs. Neuron 2001, 25:177-180
-
(2001)
Neuron
, vol.25
, pp. 177-180
-
-
Selkoe, D.J.1
-
4
-
-
0036591849
-
Lipid peroxidation and protein oxidation in Alzheimer's disease brain: Potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress
-
Butterfield DA, Lauderback CM: Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress. Free Radic Biol Med 2002, 32:1050-1060
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1050-1060
-
-
Butterfield, D.A.1
Lauderback, C.M.2
-
5
-
-
0346386580
-
Widespread peroxynitrite-mediated damage in Alzheimer's disease
-
Smith MA, Richey Harris PL, Sayre LM, Beckman JS, Perry G: Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci 1997, 17:2653-2657
-
(1997)
J Neurosci
, vol.17
, pp. 2653-2657
-
-
Smith, M.A.1
Richey Harris, P.L.2
Sayre, L.M.3
Beckman, J.S.4
Perry, G.5
-
6
-
-
0038472495
-
Proteomic identification of nitrated proteins in Alzheimer's disease brain
-
Castegna A, Thongboonkerd V, Klein JB, Lynn B, Markesbery WR, Butterfield DA: Proteomic identification of nitrated proteins in Alzheimer's disease brain. J Neurochem 2003, 85:1394-1401
-
(2003)
J Neurochem
, vol.85
, pp. 1394-1401
-
-
Castegna, A.1
Thongboonkerd, V.2
Klein, J.B.3
Lynn, B.4
Markesbery, W.R.5
Butterfield, D.A.6
-
7
-
-
0036592636
-
Amyloid β-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists
-
Butterfield DA, Griffin S, Munch G, Pasinetti GM: Amyloid β-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists. J Alzheimer's Dis 2001, 4:193-201
-
(2001)
J Alzheimer's Dis
, vol.4
, pp. 193-201
-
-
Butterfield, D.A.1
Griffin, S.2
Munch, G.3
Pasinetti, G.M.4
-
8
-
-
0028152717
-
Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
-
Mecocci P, MacGarvey U, Beal MF: Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann Neurol 1994, 36:747-751
-
(1994)
Ann Neurol
, vol.36
, pp. 747-751
-
-
Mecocci, P.1
MacGarvey, U.2
Beal, M.F.3
-
9
-
-
0033559462
-
RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease
-
Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA: RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci 1999, 19:1959-1964
-
(1999)
J Neurosci
, vol.19
, pp. 1959-1964
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
Wade, R.4
Hirai, K.5
Chiba, S.6
Smith, M.A.7
-
10
-
-
0029838063
-
Neurodegeneration, myocardial injury and perinatal death in mitochondrial superoxide dismutase deficient mice
-
Lebovitz RM, Zhang H, Vogel H, Cartwright Jr J, Dionne L, Lu N, Huang S, Matzuk MM: Neurodegeneration, myocardial injury and perinatal death in mitochondrial superoxide dismutase deficient mice. Proc Natl Acad Sci USA 1996, 93:9782-9787
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9782-9787
-
-
Lebovitz, R.M.1
Zhang, H.2
Vogel, H.3
Cartwright Jr., J.4
Dionne, L.5
Lu, N.6
Huang, S.7
Matzuk, M.M.8
-
11
-
-
0028827252
-
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
-
Li Y, Huang TT, Carlson EJ, Melov S, Ursell PC, Olson JL, Noble LJ, Yoshimura MP, Berger C, Chan PH: Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet 1995, 11:376-381
-
(1995)
Nat Genet
, vol.11
, pp. 376-381
-
-
Li, Y.1
Huang, T.T.2
Carlson, E.J.3
Melov, S.4
Ursell, P.C.5
Olson, J.L.6
Noble, L.J.7
Yoshimura, M.P.8
Berger, C.9
Chan, P.H.10
-
12
-
-
0036790385
-
Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging
-
Wei YH, Lee HC: Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging. Exp Biol Med 2002, 227:671-682
-
(2002)
Exp Biol Med
, vol.227
, pp. 671-682
-
-
Wei, Y.H.1
Lee, H.C.2
-
13
-
-
0030049032
-
Damage to DNA by reactive oxygen and nitrogen species: Role in inflammatory disease and progression to cancer
-
Wiseman H, Halliwell B: Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem J 1996, 313:17-29
-
(1996)
Biochem J
, vol.313
, pp. 17-29
-
-
Wiseman, H.1
Halliwell, B.2
-
14
-
-
0029682870
-
Oxidative damage and tyrosine nitration from peroxynitrite
-
Beckman JS: Oxidative damage and tyrosine nitration from peroxynitrite. Chem Res Toxicol 1996, 9:836-844
-
(1996)
Chem Res Toxicol
, vol.9
, pp. 836-844
-
-
Beckman, J.S.1
-
15
-
-
0031028437
-
Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of ApoE4
-
Montine KS, Olson SJ, Amarnath V, Whetsell WO, Graham DG, Montine TJ: Immunohistochemical detection of 4-hydroxy-2-nonenal adducts in Alzheimer's disease is associated with inheritance of ApoE4. Am J Pathol 1997, 150:437-443
-
(1997)
Am J Pathol
, vol.150
, pp. 437-443
-
-
Montine, K.S.1
Olson, S.J.2
Amarnath, V.3
Whetsell, W.O.4
Graham, D.G.5
Montine, T.J.6
-
16
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein
-
Games D, Adams D, Alessandrini R, Barbour R, Borthelette P, Blackwell C, Carr T, Clemens J, Donaldson T, Gillespie F, Guido T, Hagopian S, Johnson-Wood K, Khan K, Lee M, Leibowitz P, Lieberburg I, Little S, Masliah E, McConlogue L, Montoya-Zavala M, Mucke L, Paganini L, Penniman E, Power M, Schenk D, Seubert P, Snyder B, Soriano F, Tan H, Vitale J, Wadsworth S, Wolozin B, Zhao J: Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature 1995, 373:523-527
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandrini, R.3
Barbour, R.4
Borthelette, P.5
Blackwell, C.6
Carr, T.7
Clemens, J.8
Donaldson, T.9
Gillespie, F.10
Guido, T.11
Hagopian, S.12
Johnson-Wood, K.13
Khan, K.14
Lee, M.15
Leibowitz, P.16
Lieberburg, I.17
Little, S.18
Masliah, E.19
McConlogue, L.20
Montoya-Zavala, M.21
Mucke, L.22
Paganini, L.23
Penniman, E.24
Power, M.25
Schenk, D.26
Seubert, P.27
Snyder, B.28
Soriano, F.29
Tan, H.30
Vitale, J.31
Wadsworth, S.32
Wolozin, B.33
Zhao, J.34
more..
-
17
-
-
0032837741
-
The levels of soluble versus insoluble brain Aβ distinguish Alzheimer's disease from normal and pathologic aging
-
Wang J, Dickson DW, Trojanowski JQ, Lee VM: The levels of soluble versus insoluble brain Aβ distinguish Alzheimer's disease from normal and pathologic aging. Exp Neurol 1999, 158:328-337
-
(1999)
Exp Neurol
, vol.158
, pp. 328-337
-
-
Wang, J.1
Dickson, D.W.2
Trojanowski, J.Q.3
Lee, V.M.4
-
18
-
-
13044287361
-
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
-
Hsia AY, Masliah E, McConlogue L, Yu GQ, Tatsuno G, Hu K, Kholodenko D, Malenka RC, Nicoll RA, Mucke L: Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc Natl Acad Sci USA 1999, 96:3228-3233
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3228-3233
-
-
Hsia, A.Y.1
Masliah, E.2
McConlogue, L.3
Yu, G.Q.4
Tatsuno, G.5
Hu, K.6
Kholodenko, D.7
Malenka, R.C.8
Nicoll, R.A.9
Mucke, L.10
-
19
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt DR, Ratovitski T, van Lare J, Lee MK, Gonzales V, Jenkins NA, Copeland NG, Price DL, Sisodia SS: Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 1997, 19:939-945
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
Van Lare, J.3
Lee, M.K.4
Gonzales, V.5
Jenkins, N.A.6
Copeland, N.G.7
Price, D.L.8
Sisodia, S.S.9
-
20
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, Eckman C, Younkin S, Hsiao K, Duff K: Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat Med 1998, 4:97-100
-
(1998)
Nat Med
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
21
-
-
0029788661
-
Enhanced amyloidogenic processing of the β-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Aβ sequence
-
Reaume AG, Rowland DS, Trusko SP, Savage MJ, Lang DM, Greenberg BD, Siman R, Scott RW: Enhanced amyloidogenic processing of the β-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Aβ sequence. J Biol Chem 1996, 271:23380-23388
-
(1996)
J Biol Chem
, vol.271
, pp. 23380-23388
-
-
Reaume, A.G.1
Rowland, D.S.2
Trusko, S.P.3
Savage, M.J.4
Lang, D.M.5
Greenberg, B.D.6
Siman, R.7
Scott, R.W.8
-
22
-
-
0034551780
-
Presenilin-1 P264L knock-in mutation: Differential effects on Aβ production, amyloid deposition and neuronal vulnerability
-
Siman R, Reaume AG, Savage MJ, Trusko S, Lin YG, Scott RW, Flood DG: Presenilin-1 P264L knock-in mutation: differential effects on Aβ production, amyloid deposition and neuronal vulnerability. J Neurosci 2000, 20:8717-8726
-
(2000)
J Neurosci
, vol.20
, pp. 8717-8726
-
-
Siman, R.1
Reaume, A.G.2
Savage, M.J.3
Trusko, S.4
Lin, Y.G.5
Scott, R.W.6
Flood, D.G.7
-
23
-
-
0031781642
-
Detection of novel, intraneuronal pool of insoluble Aβ that accumulates with time in culture
-
Skovronsky DM, Doms RW, Lee VM: Detection of novel, intraneuronal pool of insoluble Aβ that accumulates with time in culture. J Cell Biol 1998, 141:1031-1039
-
(1998)
J Cell Biol
, vol.141
, pp. 1031-1039
-
-
Skovronsky, D.M.1
Doms, R.W.2
Lee, V.M.3
-
24
-
-
0029664624
-
42 are generated intracellularly in cultured human neurons and their secretion increases with maturation
-
42 are generated intracellularly in cultured human neurons and their secretion increases with maturation. J Biol Chem 1996, 271:8966-8970
-
(1996)
J Biol Chem
, vol.271
, pp. 8966-8970
-
-
Turner, R.S.1
Suzuki, N.2
Chyung, A.S.3
Younkin, S.G.4
Lee, V.M.5
-
25
-
-
0028322017
-
An increased percentage of long amyloid β-protein secreted by familial amyloid β-protein precursor (βAPP717) mutants
-
Suzuki N, Cheung TT, Cai XD, Odaka A, Otvos Jr L, Eckman C, Golde TE, Younkin SG: An increased percentage of long amyloid β-protein secreted by familial amyloid β-protein precursor (βAPP717) mutants. Science 1994, 264:1336-1340
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos Jr., L.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
26
-
-
0024402834
-
An assay for superoxide dismutase activity in mammalian tissue homogenates
-
Spitz DR, Oberley LW: An assay for superoxide dismutase activity in mammalian tissue homogenates. Anal Biochem 1989, 179:8-18
-
(1989)
Anal Biochem
, vol.179
, pp. 8-18
-
-
Spitz, D.R.1
Oberley, L.W.2
-
27
-
-
0029862502
-
Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts
-
MacMillan-Crow LA, Crow JP, Kerby JD, Beckman JS, Thompson JA: Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts. Proc Natl Acad Sci USA 1996, 93:11853-11858
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11853-11858
-
-
MacMillan-Crow, L.A.1
Crow, J.P.2
Kerby, J.D.3
Beckman, J.S.4
Thompson, J.A.5
-
28
-
-
0027242091
-
Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice
-
Lamb BT, Sisodia SS, Lawler AM, Slunt HH, Kitt CA, Kearns WG, Pearson PL, Price DL, Gearhart JD: Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice. Nat Genet 1993, 5:22-30
-
(1993)
Nat Genet
, vol.5
, pp. 22-30
-
-
Lamb, B.T.1
Sisodia, S.S.2
Lawler, A.M.3
Slunt, H.H.4
Kitt, C.A.5
Kearns, W.G.6
Pearson, P.L.7
Price, D.L.8
Gearhart, J.D.9
-
29
-
-
0028981717
-
The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice
-
LaFerla FM, Tinkle BT, Bieberich CJ, Haudenschild CC, Jay G: The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice. Nat Genet 1995, 9:21-30
-
(1995)
Nat Genet
, vol.9
, pp. 21-30
-
-
Laferla, F.M.1
Tinkle, B.T.2
Bieberich, C.J.3
Haudenschild, C.C.4
Jay, G.5
-
30
-
-
0029742199
-
Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice
-
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G: Correlative memory deficits, Aβ elevation, and amyloid plaques in transgenic mice. Science 1996, 274:99-102
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
31
-
-
0032886415
-
Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes
-
McGowan E, Sanders S, Iwatsubo T, Takeuchi A, Saido T, Zehr C, Yu X, Uljon S, Wang R, Mann D, Dickson D, Duff K: Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes. Neurobiol Dis 1999, 6:231-244
-
(1999)
Neurobiol Dis
, vol.6
, pp. 231-244
-
-
McGowan, E.1
Sanders, S.2
Iwatsubo, T.3
Takeuchi, A.4
Saido, T.5
Zehr, C.6
Yu, X.7
Uljon, S.8
Wang, R.9
Mann, D.10
Dickson, D.11
Duff, K.12
-
32
-
-
0033360402
-
Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice
-
Lamb BT, Bardel KA, Kulnane LS, Anderson JJ, Holtz G, Wagner SL, Sisodia SS, Hoeger EJ: Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice. Nat Neurosci 1999, 2:695-697
-
(1999)
Nat Neurosci
, vol.2
, pp. 695-697
-
-
Lamb, B.T.1
Bardel, K.A.2
Kulnane, L.S.3
Anderson, J.J.4
Holtz, G.5
Wagner, S.L.6
Sisodia, S.S.7
Hoeger, E.J.8
-
33
-
-
0036228106
-
FAD mutant PS-1 gene-targeted mice: Increased Aβ42 and Aβ deposition without APP overproduction
-
Flood DG, Reaume AG, Dorfman KS, Lin TG, Lang DM, Trusko SP, Savage MJ, Annaert WG, Strooper BD, Siman R, Scott RW: FAD mutant PS-1 gene-targeted mice: increased Aβ42 and Aβ deposition without APP overproduction. Neurobiol Aging 2002, 23:335-348
-
(2002)
Neurobiol Aging
, vol.23
, pp. 335-348
-
-
Flood, D.G.1
Reaume, A.G.2
Dorfman, K.S.3
Lin, T.G.4
Lang, D.M.5
Trusko, S.P.6
Savage, M.J.7
Annaert, W.G.8
Strooper, B.D.9
Siman, R.10
Scott, R.W.11
-
34
-
-
0028892096
-
Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence
-
DeStrooper B, Simons M, Multhaup G, Leuven FV, Beyreuther K, Dotti CG: Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence. EMBO J 1995, 14:4932-4938
-
(1995)
EMBO J
, vol.14
, pp. 4932-4938
-
-
Destrooper, B.1
Simons, M.2
Multhaup, G.3
Leuven, F.V.4
Beyreuther, K.5
Dotti, C.G.6
-
35
-
-
0035013564
-
Brain oxidative stress in animal models of accelerated aging and the age-related neurodegenerative disorders, Alzheimer's disease and Huntington's disease
-
Butterfield DA, Howard BJ, LaFontaine MA: Brain oxidative stress in animal models of accelerated aging and the age-related neurodegenerative disorders, Alzheimer's disease and Huntington's disease. Curr Med Chem 2001, 8:815-828
-
(2001)
Curr Med Chem
, vol.8
, pp. 815-828
-
-
Butterfield, D.A.1
Howard, B.J.2
LaFontaine, M.A.3
-
36
-
-
0030915855
-
Oxidative stress hypothesis in Alzheimer's disease
-
Markesbery WR: Oxidative stress hypothesis in Alzheimer's disease. Free Radic Biol Med 1997, 23:134-147
-
(1997)
Free Radic Biol Med
, vol.23
, pp. 134-147
-
-
Markesbery, W.R.1
-
37
-
-
0028882764
-
Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate
-
Dugan LL, Sensi SL, Canzoniero LM, Handran SD, Rothman SM, Goldberg MP, Choi DW: Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate. J Neurosci 1995, 15:6377-6388
-
(1995)
J Neurosci
, vol.15
, pp. 6377-6388
-
-
Dugan, L.L.1
Sensi, S.L.2
Canzoniero, L.M.3
Handran, S.D.4
Rothman, S.M.5
Goldberg, M.P.6
Choi, D.W.7
-
38
-
-
0030060186
-
Mitochondrial generation of reactive oxygen species after brain ischemia in the rat
-
Piantadosi CA, Zhang J: Mitochondrial generation of reactive oxygen species after brain ischemia in the rat. Stroke 1996, 27:327-331
-
(1996)
Stroke
, vol.27
, pp. 327-331
-
-
Piantadosi, C.A.1
Zhang, J.2
-
40
-
-
0029982815
-
Oxidative damage in Alzheimer's
-
Smith MA, Perry G, Richey PL, Sayre LM, Anderson VE, Beal MF, Kowall N: Oxidative damage in Alzheimer's. Nature 1996, 382:120-121
-
(1996)
Nature
, vol.382
, pp. 120-121
-
-
Smith, M.A.1
Perry, G.2
Richey, P.L.3
Sayre, L.M.4
Anderson, V.E.5
Beal, M.F.6
Kowall, N.7
-
41
-
-
0032147208
-
Biological tyrosine nitration: A pathophysiological function of nitric oxide and reactive oxygen species
-
Ischiropoulos H: Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species. Arch Biochem Biophys 1998, 356:1-11
-
(1998)
Arch Biochem Biophys
, vol.356
, pp. 1-11
-
-
Ischiropoulos, H.1
-
42
-
-
0037192407
-
Age related changes in the distribution of nitrotyrosine in the cerebral cortex and hippocampus of rats
-
Shin CM, Chung YH, Kim MJ, Lee EY, Kim EG, Cha CI: Age related changes in the distribution of nitrotyrosine in the cerebral cortex and hippocampus of rats. Brain Res 2002, 931:194-199
-
(2002)
Brain Res
, vol.931
, pp. 194-199
-
-
Shin, C.M.1
Chung, Y.H.2
Kim, M.J.3
Lee, E.Y.4
Kim, E.G.5
Cha, C.I.6
-
43
-
-
0033516677
-
Alterations of 3-nitrotyrosine concentration in the cerebrospinal fluid during aging and in patients with Alzheimer's disease
-
Tohgi H, Abe T, Yamazaki K, Murata T, Ishizaki E, Isobe C: Alterations of 3-nitrotyrosine concentration in the cerebrospinal fluid during aging and in patients with Alzheimer's disease. Neurosci Lett 1999, 269:52-54
-
(1999)
Neurosci Lett
, vol.269
, pp. 52-54
-
-
Tohgi, H.1
Abe, T.2
Yamazaki, K.3
Murata, T.4
Ishizaki, E.5
Isobe, C.6
-
44
-
-
0032806355
-
Increased microglial activation and protein nitration in white matter of the aging monkey
-
Sloane JA, Hollander W, Moss MB, Rosene DL, Abraham CR: Increased microglial activation and protein nitration in white matter of the aging monkey. Neurobiol Aging 1999, 20:395-405
-
(1999)
Neurobiol Aging
, vol.20
, pp. 395-405
-
-
Sloane, J.A.1
Hollander, W.2
Moss, M.B.3
Rosene, D.L.4
Abraham, C.R.5
-
45
-
-
0026485192
-
Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase
-
Ischiropoulos H, Zhu L, Chen J, Tasi M, Martin JC, Smith CD, Beckman JS: Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch Biochem Biophys 1992, 298:431-437
-
(1992)
Arch Biochem Biophys
, vol.298
, pp. 431-437
-
-
Ischiropoulos, H.1
Zhu, L.2
Chen, J.3
Tasi, M.4
Martin, J.C.5
Smith, C.D.6
Beckman, J.S.7
-
46
-
-
0029994350
-
Catalytic properties of human manganese superoxide dismutase
-
Hsu JL, Hsieh Y, Tu C, O'Connor D, Nick HS, Silverman DN: Catalytic properties of human manganese superoxide dismutase. J Biol Chem 1996, 271:17687-17691
-
(1996)
J Biol Chem
, vol.271
, pp. 17687-17691
-
-
Hsu, J.L.1
Hsieh, Y.2
Tu, C.3
O'Connor, D.4
Nick, H.S.5
Silverman, D.N.6
-
47
-
-
0029998238
-
Differential inhibitory action of nitric oxide and peroxynitrite on mitochondrial electron transport
-
Cassina A, Radi R: Differential inhibitory action of nitric oxide and peroxynitrite on mitochondrial electron transport. Arch Biochem Biophys 1996, 328:309-316
-
(1996)
Arch Biochem Biophys
, vol.328
, pp. 309-316
-
-
Cassina, A.1
Radi, R.2
-
48
-
-
0035667004
-
Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration
-
Baldus S, Eiserich JP, Mani A, Castro L, Figueroa M, Chumley P, Ma W, Tousson A, White CR, Bullard DC, Brennan ML, Lusis AJ, Moore KP, Freeman BA: Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration. J Clin Invest 2001, 108:1759-1770
-
(2001)
J Clin Invest
, vol.108
, pp. 1759-1770
-
-
Baldus, S.1
Eiserich, J.P.2
Mani, A.3
Castro, L.4
Figueroa, M.5
Chumley, P.6
Ma, W.7
Tousson, A.8
White, C.R.9
Bullard, D.C.10
Brennan, M.L.11
Lusis, A.J.12
Moore, K.P.13
Freeman, B.A.14
-
49
-
-
0036801357
-
Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases
-
Baldus S, Eiserich JP, Brennan ML, Jackson RM, Alexander CB, Freeman BA: Spatial mapping of pulmonary and vascular nitrotyrosine reveals the pivotal role of myeloperoxidase as a catalyst for tyrosine nitration in inflammatory diseases. Free Radic Biol Med 2002, 33:1010-1019
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1010-1019
-
-
Baldus, S.1
Eiserich, J.P.2
Brennan, M.L.3
Jackson, R.M.4
Alexander, C.B.5
Freeman, B.A.6
-
50
-
-
0031957224
-
Microglia, scavenger receptors, and the pathogenesis of Alzheimer's disease
-
El Khoury J, Hickman SE, Thomas CA, Loike JD, Silverstein SC: Microglia, scavenger receptors, and the pathogenesis of Alzheimer's disease. Neurobiol Aging 1998, 19:S81-S84
-
(1998)
Neurobiol Aging
, vol.19
-
-
El Khoury, J.1
Hickman, S.E.2
Thomas, C.A.3
Loike, J.D.4
Silverstein, S.C.5
-
51
-
-
0028953529
-
Activation of microglial cells by beta-amyloid protein and interferon-gamma
-
Meda L, Cassatella MA, Szendrei GI, Otvos Jr L, Baron P, Villalba M, Ferrari D, Rossi F: Activation of microglial cells by beta-amyloid protein and interferon-gamma. Nature 1995, 374:647-650
-
(1995)
Nature
, vol.374
, pp. 647-650
-
-
Meda, L.1
Cassatella, M.A.2
Szendrei, G.I.3
Otvos Jr., L.4
Baron, P.5
Villalba, M.6
Ferrari, D.7
Rossi, F.8
-
52
-
-
0033004381
-
Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease
-
Reynolds WF, Rhees J, Maciejewski D, Paladino T, Sieburg H, Maki RA, Masliah E: Myeloperoxidase polymorphism is associated with gender specific risk for Alzheimer's disease. Exp Neurol 1999, 155:31-41
-
(1999)
Exp Neurol
, vol.155
, pp. 31-41
-
-
Reynolds, W.F.1
Rhees, J.2
Maciejewski, D.3
Paladino, T.4
Sieburg, H.5
Maki, R.A.6
Masliah, E.7
-
53
-
-
0032080117
-
Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome
-
Grune T, Blasig IE, Sitte N, Roloff B, Haseloff R, Davies KJ: Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome. J Biol Chem 1998, 273:10857-10862
-
(1998)
J Biol Chem
, vol.273
, pp. 10857-10862
-
-
Grune, T.1
Blasig, I.E.2
Sitte, N.3
Roloff, B.4
Haseloff, R.5
Davies, K.J.6
-
54
-
-
0034663360
-
Proteolytic degradation of tyrosine nitrated proteins
-
Souza JM, Choi I, Chen Q, Weisse M, Daikhin E, Yudkoff M, Obin M, Ara J, Horwitz J, Ischiropoulos H: Proteolytic degradation of tyrosine nitrated proteins. Arch Biochem Biophys 2000, 380:360-366
-
(2000)
Arch Biochem Biophys
, vol.380
, pp. 360-366
-
-
Souza, J.M.1
Choi, I.2
Chen, Q.3
Weisse, M.4
Daikhin, E.5
Yudkoff, M.6
Obin, M.7
Ara, J.8
Horwitz, J.9
Ischiropoulos, H.10
-
55
-
-
0030002384
-
Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation
-
Gow AJ, Duran D, Malcolm S, Ischiropoulos H: Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation. FEBS Lett 1996, 385:63-66
-
(1996)
FEBS Lett
, vol.385
, pp. 63-66
-
-
Gow, A.J.1
Duran, D.2
Malcolm, S.3
Ischiropoulos, H.4
-
56
-
-
0032578514
-
An activity in rat tissues that modifies nitrotyrosine-containing proteins
-
Kamisaki Y, Wada K, Bian K, Balabanli B, Davis K, Martin E. Behbod F, Lee YC, Murad F: An activity in rat tissues that modifies nitrotyrosine-containing proteins. Proc Natl Acad Sci USA 1998, 95:11584-11589
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11584-11589
-
-
Kamisaki, Y.1
Wada, K.2
Bian, K.3
Balabanli, B.4
Davis, K.5
Martin, E.6
Behbod, F.7
Lee, Y.C.8
Murad, F.9
-
57
-
-
0035895888
-
Selective targeting of a redox-active ubiquinone to mitochondria within cells: Antioxidant and antiapoptotic properties
-
Keiso GF, Porteous CM, Coulter CV, Hughes G, Porteous WK, Ledgerwood EC, Smith RA, Murphy MP: Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties. J Biol Chem 2001, 276:4588-4596
-
(2001)
J Biol Chem
, vol.276
, pp. 4588-4596
-
-
Keiso, G.F.1
Porteous, C.M.2
Coulter, C.V.3
Hughes, G.4
Porteous, W.K.5
Ledgerwood, E.C.6
Smith, R.A.7
Murphy, M.P.8
-
58
-
-
0037033039
-
Superoxide activates mitochondrial uncoupling protein 2 from matrix side. Studies using targeted antioxidants
-
Echtay KS, Murphy MP, Smith RA, Talbot DA, Brand MD: Superoxide activates mitochondrial uncoupling protein 2 from matrix side. Studies using targeted antioxidants. J Biol Chem 2002, 277:47129-47135
-
(2002)
J Biol Chem
, vol.277
, pp. 47129-47135
-
-
Echtay, K.S.1
Murphy, M.P.2
Smith, R.A.3
Talbot, D.A.4
Brand, M.D.5
-
59
-
-
20444392739
-
Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools
-
James AM, Cocheme HM, Smith RA, Murphy MP: Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools. J Biol Chem 2005, 280:21295-21312
-
(2005)
J Biol Chem
, vol.280
, pp. 21295-21312
-
-
James, A.M.1
Cocheme, H.M.2
Smith, R.A.3
Murphy, M.P.4
-
60
-
-
4444315545
-
Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis
-
Dhanasekaran A, Kotamraju S, Kalivendi SV, Matsunaga T, Shang T, Keszler A, Joseph J, Kalyanaraman B: Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis. J Biol Chem 2004, 279:37575-37587
-
(2004)
J Biol Chem
, vol.279
, pp. 37575-37587
-
-
Dhanasekaran, A.1
Kotamraju, S.2
Kalivendi, S.V.3
Matsunaga, T.4
Shang, T.5
Keszler, A.6
Joseph, J.7
Kalyanaraman, B.8
-
61
-
-
0029125857
-
Aging, energy and oxidative stress in neurodegenerative diseases
-
Beal MF: Aging, energy and oxidative stress in neurodegenerative diseases. Ann Neurol 1995, 38:357-366
-
(1995)
Ann Neurol
, vol.38
, pp. 357-366
-
-
Beal, M.F.1
-
62
-
-
0033080175
-
Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice
-
Yen HC, Oberley TD, Oberley C, Gairola CG, Szweda LI, St. Clair DK: Manganese superoxide dismutase protects mitochondrial complex I against adriamycin-induced cardiomyopathy in transgenic mice. Arch Biochem Biophys 1999, 362:59-66
-
(1999)
Arch Biochem Biophys
, vol.362
, pp. 59-66
-
-
Yen, H.C.1
Oberley, T.D.2
Oberley, C.3
Gairola, C.G.4
Szweda, L.I.5
St. Clair, D.K.6
-
64
-
-
0035956929
-
Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis
-
Kokoszka JE, Coskun P, Esposito LA, Wallace DC: Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis. Proc Natl Acad Sci USA 2001, 98: 2278-2283
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2278-2283
-
-
Kokoszka, J.E.1
Coskun, P.2
Esposito, L.A.3
Wallace, D.C.4
-
65
-
-
0034838078
-
Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis
-
Van Remmen H, Williams MD, Quo Z, Estlack L, Yang H, Carlson EJ, Epstein CJ, Huang TT, Richardson A: Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis. Am J Physiol 2001, 281:H1422-H1432
-
(2001)
Am J Physiol
, vol.281
-
-
Van Remmen, H.1
Williams, M.D.2
Quo, Z.3
Estlack, L.4
Yang, H.5
Carlson, E.J.6
Epstein, C.J.7
Huang, T.T.8
Richardson, A.9
-
66
-
-
0024980878
-
Liver mitochondrial respiratory functions decline with age
-
Yen TC, Chen YS, King KL, Yeh SH, Wei YH: Liver mitochondrial respiratory functions decline with age. Biochem Biophys Res Commun 1989, 165:994-1003
-
(1989)
Biochem Biophys Res Commun
, vol.165
, pp. 994-1003
-
-
Yen, T.C.1
Chen, Y.S.2
King, K.L.3
Yeh, S.H.4
Wei, Y.H.5
-
67
-
-
0026469073
-
Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: Effect of ageing
-
Cooper JM, Mann VM, Schapira AH: Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing. J Neurol Sci 1992, 113:91-98
-
(1992)
J Neurol Sci
, vol.113
, pp. 91-98
-
-
Cooper, J.M.1
Mann, V.M.2
Schapira, A.H.3
-
68
-
-
2542505678
-
Oxidative stress and mitochondrial DNA mutations in human aging
-
Wei YH: Oxidative stress and mitochondrial DNA mutations in human aging. Proc Soc Exp Biol Med 1998, 217:53-63
-
(1998)
Proc Soc Exp Biol Med
, vol.217
, pp. 53-63
-
-
Wei, Y.H.1
-
69
-
-
0034612075
-
A selective defect of cytochrome C oxidase is present in brain of Alzheimer disease patients
-
Maurer I, Zierz S, Moller HJ: A selective defect of cytochrome C oxidase is present in brain of Alzheimer disease patients. Neurobiol Aging 2000, 21:455-462
-
(2000)
Neurobiol Aging
, vol.21
, pp. 455-462
-
-
Maurer, I.1
Zierz, S.2
Moller, H.J.3
-
70
-
-
0032944035
-
Decreased brain protein levels of cytochrome oxidase subunits in Alzheimer's disease and in hereditary spinocerebellar ataxia disorders: A nonspecific change?
-
Kish SJ, Mastrogiacomo F, Guttman M, Furukawa Y, Taanman JW, Dozic S, Pandolfo M, Lamarche J, DiStefano L, Chang LJ: Decreased brain protein levels of cytochrome oxidase subunits in Alzheimer's disease and in hereditary spinocerebellar ataxia disorders: a nonspecific change? J Neurochem 1999, 72:700-707
-
(1999)
J Neurochem
, vol.72
, pp. 700-707
-
-
Kish, S.J.1
Mastrogiacomo, F.2
Guttman, M.3
Furukawa, Y.4
Taanman, J.W.5
Dozic, S.6
Pandolfo, M.7
Lamarche, J.8
Distefano, L.9
Chang, L.J.10
-
71
-
-
0642375798
-
Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease
-
Eckert A, Keil U, Marques CA, Bonert A, Frey C, Schussel K, Muller WE: Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease. Biochem Pharmacol 2003, 66:1627-1634
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 1627-1634
-
-
Eckert, A.1
Keil, U.2
Marques, C.A.3
Bonert, A.4
Frey, C.5
Schussel, K.6
Muller, W.E.7
-
72
-
-
0027500793
-
Free radicals in the genesis of Alzheimer's disease
-
Richardson JS: Free radicals in the genesis of Alzheimer's disease. Ann NY Acad Sci 1993, 695:73-76
-
(1993)
Ann NY Acad Sci
, vol.695
, pp. 73-76
-
-
Richardson, J.S.1
-
73
-
-
0021984002
-
Superoxide dismutase isoenzymes in normal brains and in brains from patients with dementia of Alzheimer type
-
Marklund SL, Adolfsson R, Gottfries CG, Windblad B: Superoxide dismutase isoenzymes in normal brains and in brains from patients with dementia of Alzheimer type. J Neural Sci 1985, 67:319-325
-
(1985)
J Neural Sci
, vol.67
, pp. 319-325
-
-
Marklund, S.L.1
Adolfsson, R.2
Gottfries, C.G.3
Windblad, B.4
-
74
-
-
0029902166
-
Evidence of neuronal oxidative damage in Alzheimer's disease
-
Good PF, Werner P, Hsu A, Olanow CW, Perl DP: Evidence of neuronal oxidative damage in Alzheimer's disease. Am J Pathol 1996, 149:21-28
-
(1996)
Am J Pathol
, vol.149
, pp. 21-28
-
-
Good, P.F.1
Werner, P.2
Hsu, A.3
Olanow, C.W.4
Perl, D.P.5
-
75
-
-
10244235267
-
Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease
-
Vodovotz Y, Lucia MS, Flanders KC, Chesler L, Xie QW, Smith TW, Weidner J, Mumford R, Webber R, Nathan C, Roberts AB, Lippa CF, Sporn MB: Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease. J Exp Med 1996, 184:1425-1433
-
(1996)
J Exp Med
, vol.184
, pp. 1425-1433
-
-
Vodovotz, Y.1
Lucia, M.S.2
Flanders, K.C.3
Chesler, L.4
Xie, Q.W.5
Smith, T.W.6
Weidner, J.7
Mumford, R.8
Webber, R.9
Nathan, C.10
Roberts, A.B.11
Lippa, C.F.12
Sporn, M.B.13
-
76
-
-
85047693458
-
Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: Cause or effect?
-
Dickson DW: Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect? J Clin Invest 2004, 114:23-27
-
(2004)
J Clin Invest
, vol.114
, pp. 23-27
-
-
Dickson, D.W.1
|