Steady-state kinetic characterization of kinase activity and requirements for mg2+ of interleukin-1 receptor-associated kinase-4

Biochemistry

Volumn 49, Issue 7, 2010, Pages 1495-1506

  Hekmat Nejad, Mohammad ^a   Cai, Terrence ^a   Swinney, David C ^a  

^a ROCHE BIOSCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION LOOPS; ATP BINDING; CATALYTIC ACTIVITY; CHELATE COMPLEX; DIVALENT METALS; INTERLEUKIN-1; INTRACELLULAR SIGNALING; KINASE ACTIVITY; KINETIC EVIDENCE; KINETIC MECHANISM; PEPTIDE SUBSTRATES; PHOSPHORYL TRANSFER; PHYSIOLOGICAL FUNCTIONS; PRODUCT INHIBITION; PROTEIN KINASE; RANDOM MECHANISMS; STEADY-STATE KINETICS;

BINDING ENERGY; BINDING SITES; BIOCHEMISTRY; COMPLEXATION; ENZYMES; PEPTIDES;

ENZYME INHIBITION;

ADENOSINE TRIPHOSPHATE; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; MAGNESIUM ION; RECOMBINANT ENZYME;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME KINETICS; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; PRIORITY JOURNAL; STEADY STATE;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; CELL LINE; ENZYME ACTIVATION; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; KINETICS; MAGNESIUM; MOLECULAR SEQUENCE DATA; PEPTIDES; PHOSPHORYLATION; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SPODOPTERA; SUBSTRATE SPECIFICITY;

EID: 77449154335     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi901609m     Document Type: Article

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