Kinetic mechanism of the p38-α MAP kinase: Phosphoryl transfer to synthetic peptides

Biochemistry

Volumn 39, Issue 8, 2000, Pages 2079-2087

  Chen, Guanjing ^a   Porter, Margaret D ^a   Bristol, John R ^a   Fitzgibbon, Matthew J ^a   Pazhanisamy, S ^a  

^a VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATE; PROTEIN SERINE THREONINE KINASE; SYNTHETIC PEPTIDE;

ARTICLE; COMPETITIVE INHIBITION; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE; ISOMERISM; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; VISCOSITY;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; IMIDAZOLES; KINETICS; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDES; PHOSPHORYLATION; PROLINE; PROTEIN BINDING; PYRIDINES; SERINE; THREONINE; VISCOSITY;

FELIS CATUS;

EID: 0034728352     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9919495     Document Type: Article

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