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Volumn 17, Issue 1, 2010, Pages 78-85

Dissecting the role of ubiquitylation in the DNA damage response checkpoint in G2

Author keywords

cell cycle; checkpoint; DNA damage response; G2 phase; Ubiquitylation

Indexed keywords

PROTEASOME; UBIQUITIN; UBIQUITIN PROTEIN LIGASE; ANAPHASE PROMOTING COMPLEX; ANAPHASE-PROMOTING COMPLEX; CYCLIN DEPENDENT KINASE 1;

EID: 77449097602     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2009.104     Document Type: Review
Times cited : (31)

References (80)
  • 1
    • 3142534591 scopus 로고    scopus 로고
    • Initiating cellular stress responses
    • DOI 10.1016/j.cell.2004.06.023, PII S0092867404006166
    • Bakkenist CJ, Kastan MB. Initiating cellular stress responses. Cell 2004; 118: 9-17. (Pubitemid 38902810)
    • (2004) Cell , vol.118 , Issue.1 , pp. 9-17
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 2
    • 36749022214 scopus 로고    scopus 로고
    • The DNA Damage Response: Ten Years After
    • DOI 10.1016/j.molcel.2007.11.015, PII S1097276507007836
    • Harper JW, Elledge SJ. The DNA damage response: ten years after. Mol Cell 2007; 28: 739-745. (Pubitemid 350217064)
    • (2007) Molecular Cell , vol.28 , Issue.5 , pp. 739-745
    • Harper, J.W.1    Elledge, S.J.2
  • 3
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • DOI 10.1038/nature03097
    • Kastan MB, Bartek J. Cell-cycle checkpoints and cancer. Nature 2004; 432: 316-323. (Pubitemid 39551659)
    • (2004) Nature , vol.432 , Issue.7015 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 4
    • 41149094512 scopus 로고    scopus 로고
    • Regulation of DNA repair throughout the cell cycle
    • DOI 10.1038/nrm2351, PII NRM2351
    • Branzei D, Foiani M. Regulation of DNA repair throughout the cell cycle. Nat Rev Mol Cell Biol 2008; 9: 297-308. (Pubitemid 351430844)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.4 , pp. 297-308
    • Branzei, D.1    Foiani, M.2
  • 5
    • 3242890575 scopus 로고    scopus 로고
    • Mammalian cell cycle checkpoints: Signalling pathways and their organization in space and time
    • DOI 10.1016/j.dnarep.2004.03.006, PII S1568786404000655
    • Lukas J, Lukas C, Bartek J. Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time. DNA Repair (Amst) 2004; 3: 997-1007. (Pubitemid 38997942)
    • (2004) DNA Repair , vol.3 , Issue.8-9 , pp. 997-1007
    • Lukas, J.1    Lukas, C.2    Bartek, J.3
  • 6
    • 39449085063 scopus 로고    scopus 로고
    • DNA-damage repair; the good, the bad, and the ugly
    • DOI 10.1038/emboj.2008.15, PII EMBOJ200815
    • Hakem R. DNA-damage repair; the good, the bad, and the ugly. EMBO J 2008; 27: 589-605. (Pubitemid 351273123)
    • (2008) EMBO Journal , vol.27 , Issue.4 , pp. 589-605
    • Hakem, R.1
  • 7
    • 33747376928 scopus 로고    scopus 로고
    • DNA repair pathways in clinical practice: Lessons from pediatric cancer susceptibility syndromes
    • DOI 10.1200/JCO.2005.05.4171
    • Kennedy RD, D'ndrea AD. DNA repair pathways in clinical practice: lessons from pediatric cancer susceptibility syndromes. J Clin Oncol 2006; 24: 3799-3808. (Pubitemid 46622318)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.23 , pp. 3799-3808
    • Kennedy, R.D.1    D'Andrea, A.D.2
  • 8
    • 17644409069 scopus 로고    scopus 로고
    • ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
    • DOI 10.1126/science.1108297
    • Lee JH, Paull TT. ATM activation by DNA double-strand breaks through the Mre11-Rad50- Nbs1 complex. Science 2005; 308: 551-554. (Pubitemid 40570585)
    • (2005) Science , vol.308 , Issue.5721 , pp. 551-554
    • Lee, J.-H.1    Paull, T.T.2
  • 9
    • 15844394846 scopus 로고    scopus 로고
    • Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
    • DOI 10.1038/nature03442
    • Falck J, Coates J, Jackson SP. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature 2005; 434: 605-611. (Pubitemid 40488547)
    • (2005) Nature , vol.434 , Issue.7033 , pp. 605-611
    • Falck, J.1    Coates, J.2    Jackson, S.P.3
  • 10
    • 30344463835 scopus 로고    scopus 로고
    • ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
    • DOI 10.1038/ncb1337, PII N1337
    • Jazayeri A, Falck J, Lukas C, Bartek J, Smith GC, Lukas J et al. ATM- and cell cycledependent regulation of ATR in response to DNA double-strand breaks. Nat Cell Biol 2006; 8: 37-45. (Pubitemid 43064795)
    • (2006) Nature Cell Biology , vol.8 , Issue.1 , pp. 37-45
    • Jazayeri, A.1    Falck, J.2    Lukas, C.3    Bartek, J.4    Smith, G.C.M.5    Lukas, J.6    Jackson, S.P.7
  • 11
    • 33847737716 scopus 로고    scopus 로고
    • DNA damage checkpoints: from initiation to recovery or adaptation
    • DOI 10.1016/j.ceb.2007.02.009, PII S0955067407000233
    • Bartek J, Lukas J. DNA damage checkpoints: from initiation to recovery or adaptation. Curr Opin Cell Biol 2007; 19: 238-245. (Pubitemid 46386406)
    • (2007) Current Opinion in Cell Biology , vol.19 , Issue.2 , pp. 238-245
    • Bartek, J.1    Lukas, J.2
  • 12
    • 4444318673 scopus 로고    scopus 로고
    • The SCF ubiquitin ligase: Insights into a molecular machine
    • DOI 10.1038/nrm1471
    • Cardozo T, Pagano M. The SCF ubiquitin ligase: insights into a molecular machine. Nat Rev Mol Cell Biol 2004; 5: 739-751. (Pubitemid 39208183)
    • (2004) Nature Reviews Molecular Cell Biology , vol.5 , Issue.9 , pp. 739-751
    • Cardozo, T.1    Pagano, M.2
  • 13
    • 33747589184 scopus 로고    scopus 로고
    • The anaphase promoting complex/cyclosome: A machine designed to destroy
    • Peters JM. The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell Biol 2006; 7: 644-656.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 644-656
    • Peters, J.M.1
  • 14
    • 70549088824 scopus 로고    scopus 로고
    • The function of APC/CCdh1 in cell cycle and beyond
    • Li M, Zhang P. The function of APC/CCdh1 in cell cycle and beyond. Cell Div 2009; 4: 2.
    • (2009) Cell Div , vol.4 , pp. 2
    • Li, M.1    Zhang, P.2
  • 15
    • 44349122993 scopus 로고    scopus 로고
    • Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: Tipping the scales of cancer
    • DOI 10.1038/nrc2396, PII NRC2396
    • Frescas D, Pagano M. Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer. Nat Rev Cancer 2008; 8: 438-449. (Pubitemid 351744963)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.6 , pp. 438-449
    • Frescas, D.1    Pagano, M.2
  • 18
    • 1642399624 scopus 로고    scopus 로고
    • Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
    • DOI 10.1038/nature02381
    • Wei W, Ayad NG, Wan Y, Zhang GJ, Kirschner MW, Kaelin Jr WG. Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex. Nature 2004; 428: 194-198. (Pubitemid 38374317)
    • (2004) Nature , vol.428 , Issue.6979 , pp. 194-198
    • Wei, W.1    Ayad, N.G.2    Wan, Y.3    Zhang, G.-J.4    Kirschner, M.W.5    Kaelin Jr., W.G.6
  • 19
    • 1642378661 scopus 로고    scopus 로고
    • Cdh1 ubiquitin ligase
    • DOI 10.1038/nature02330
    • Bashir T, Dorrello NV, Amador V, Guardavaccaro D, Pagano M. Control of the SCF(Skp2- Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase. Nature 2004; 428: 190-193. (Pubitemid 38374316)
    • (2004) Nature , vol.428 , Issue.6979 , pp. 190-193
    • Bashir, T.1    Dorello, H.V.2    Amador, V.3    Guardavaccaro, D.4    Pagano, M.5
  • 20
    • 25444517778 scopus 로고    scopus 로고
    • Involvement of the SCF complex in the control of Cdh1 degradation in S-phase
    • Benmaamar R, Pagano M. Involvement of the SCF complex in the control of Cdh1 degradation in S-phase. Cell Cycle 2005; 4: 1230-1232. (Pubitemid 41365394)
    • (2005) Cell Cycle , vol.4 , Issue.9 , pp. 1230-1232
    • Benmaamar, R.1    Pagano, M.2
  • 21
    • 33645960654 scopus 로고    scopus 로고
    • Stabilizers and destabilizers controlling cell cycle oscillators
    • Guardavaccaro D, Pagano M. Stabilizers and destabilizers controlling cell cycle oscillators. Mol Cell 2006; 22: 1-4.
    • (2006) Mol Cell , vol.22 , pp. 1-4
    • Guardavaccaro, D.1    Pagano, M.2
  • 22
    • 0033634679 scopus 로고    scopus 로고
    • Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts
    • Kumagai A, Dunphy WG. Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts. Mol Cell 2000; 6: 839-849.
    • (2000) Mol Cell , vol.6 , pp. 839-849
    • Kumagai, A.1    Dunphy, W.G.2
  • 23
    • 56949105254 scopus 로고    scopus 로고
    • Polo-like kinase 1 reaches beyond mitosis-cytokinesis, DNA damage response, and development
    • Takaki T, Trenz K, Costanzo V, Petronczki M. Polo-like kinase 1 reaches beyond mitosis-cytokinesis, DNA damage response, and development. Curr Opin Cell Biol 2008; 20: 650-660.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 650-660
    • Takaki, T.1    Trenz, K.2    Costanzo, V.3    Petronczki, M.4
  • 25
    • 0347361537 scopus 로고    scopus 로고
    • β-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase
    • DOI 10.1101/gad.1157503
    • Jin J, Shirogane T, Xu L, Nalepa G, Qin J, Elledge SJ et al. SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase. Genes Dev 2003; 17: 3062-3074. (Pubitemid 38040770)
    • (2003) Genes and Development , vol.17 , Issue.24 , pp. 3062-3074
    • Jin, J.1    Shirogane, T.2    Xu, L.3    Nalepa, G.4    Qin, J.5    Elledge, S.J.6    Harper, J.W.7
  • 26
    • 0025324692 scopus 로고
    • Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2
    • Sadhu K, Reed SI, Richardson H, Russell P. Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2. Proc Natl Acad Sci USA 1990; 87: 5139-5143.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 5139-5143
    • Sadhu, K.1    Reed, S.I.2    Richardson, H.3    Russell, P.4
  • 27
    • 0026319225 scopus 로고
    • Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins
    • Galaktionov K, Beach D. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins. Cell 1991; 67: 1181-1194. (Pubitemid 121001530)
    • (1991) Cell , vol.67 , Issue.6 , pp. 1181-1194
    • Galaktionov, K.1    Beach, D.2
  • 28
    • 34250865564 scopus 로고    scopus 로고
    • CDC25 phosphatases in cancer cells: Key players? Good targets?
    • DOI 10.1038/nrc2169, PII NRC2169
    • Boutros R, Lobjois V, Ducommun B. CDC25 phosphatases in cancer cells: key players? Good targets? Nat Rev Cancer 2007; 7: 495-507. (Pubitemid 46985396)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.7 , pp. 495-507
    • Boutros, R.1    Lobjois, V.2    Ducommun, B.3
  • 29
    • 0026234297 scopus 로고
    • An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells
    • Nagata A, Igarashi M, Jinno S, Suto K, Okayama H. An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells. New Biol 1991; 3: 959-968.
    • (1991) New Biol , vol.3 , pp. 959-968
    • Nagata, A.1    Igarashi, M.2    Jinno, S.3    Suto, K.4    Okayama, H.5
  • 31
    • 13244256828 scopus 로고    scopus 로고
    • 2/M transition
    • Perdiguero E, Nebreda AR. Regulation of Cdc25C activity during the meiotic G2/M transition. Cell Cycle 2004; 3: 733-737. (Pubitemid 40187901)
    • (2004) Cell Cycle , vol.3 , Issue.6 , pp. 733-737
    • Perdiguero, E.1    Nebreda, A.R.2
  • 32
    • 0036847320 scopus 로고    scopus 로고
    • 2/M events by Cdc25A through phosphorylation-dependent modulation of its stability
    • DOI 10.1093/emboj/cdf567
    • Mailand N, Podtelejnikov AV, Groth A, Mann M, Bartek J, Lukas J. Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability. EMBO J 2002; 21: 5911-5920. (Pubitemid 35315288)
    • (2002) EMBO Journal , vol.21 , Issue.21 , pp. 5911-5920
    • Mailand, N.1    Podtelejnikov, A.V.2    Groth, A.3    Mann, M.4    Bartek, J.5    Lukas, J.6
  • 33
    • 0028022034 scopus 로고
    • 1/S transition
    • Hoffmann I, Draetta G, Karsenti E. Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition. EMBO J 1994; 13: 4302-4310. (Pubitemid 24295202)
    • (1994) EMBO Journal , vol.13 , Issue.18 , pp. 4302-4310
    • Hoffmann, I.1    Draetta, G.2    Karsenti, E.3
  • 35
    • 15044365805 scopus 로고    scopus 로고
    • Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases
    • DOI 10.1128/MCB.25.7.2853-2860.2005
    • Ferguson AM, White LS, Donovan PJ, Piwnica-Worms H. Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases. Mol Cell Biol 2005; 25: 2853-2860. (Pubitemid 40381646)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.7 , pp. 2853-2860
    • Ferguson, A.M.1    White, L.S.2    Donovan, P.J.3    Piwnica-Worms, H.4
  • 36
    • 1842486794 scopus 로고    scopus 로고
    • Cdc25A phosphatase: Combinatorial phosphorylation, ubiquitylation and proteolysis
    • DOI 10.1038/sj.onc.1207394
    • Busino L, Chiesa M, Draetta GF, Donzelli M. Cdc25A phosphatase: combinatorial phosphorylation, ubiquitylation and proteolysis. Oncogene 2004; 23: 2050-2056. (Pubitemid 38496734)
    • (2004) Oncogene , vol.23 , Issue.11 REV. ISS. 1 , pp. 2050-2056
    • Busino, L.1    Chiesa, M.2    Draetta, G.F.3    Donzelli, M.4
  • 37
    • 33847013064 scopus 로고    scopus 로고
    • Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability
    • Ray D, Terao Y, Fuhrken PG, Ma ZQ, DeMayo FJ, Christov K et al. Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability. Cancer Res 2007; 67: 984-991.
    • (2007) Cancer Res , vol.67 , pp. 984-991
    • Ray, D.1    Terao, Y.2    Fuhrken, P.G.3    Ma, Z.Q.4    Demayo, F.J.5    Christov, K.6
  • 38
    • 0033592688 scopus 로고    scopus 로고
    • Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex
    • Lukas C, Sorensen CS, Kramer E, Santoni-Rugiu E, Lindeneg C, Peters JM et al. Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex. Nature 1999; 401: 815-818.
    • (1999) Nature , vol.401 , pp. 815-818
    • Lukas, C.1    Sorensen, C.S.2    Kramer, E.3    Santoni-Rugiu, E.4    Lindeneg, C.5    Peters, J.M.6
  • 39
    • 0001616078 scopus 로고    scopus 로고
    • A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression
    • DOI 10.1128/MCB.21.11.3692-3703.2001
    • Sorensen CS, Lukas C, Kramer ER, Peters JM, Bartek J, Lukas J. A conserved cyclinbinding domain determines functional interplay between anaphase-promoting complex- Cdh1 and cyclin A-Cdk2 during cell cycle progression. Mol Cell Biol 2001; 21: 3692-3703. (Pubitemid 32466983)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.11 , pp. 3692-3703
    • S'Orensen, C.S.1    Lukas, C.2    Kramer, E.R.3    Peters, J.-M.4    Bartek, J.5    Lukas, J.6
  • 40
    • 33645298454 scopus 로고    scopus 로고
    • Dual regulation of the anaphase promoting complex in human cells by cyclin A-Cdk2 and cyclin A-Cdk1 complexes
    • Mitra J, Enders GH, Azizkhan-Clifford J, Lengel KL. Dual regulation of the anaphase promoting complex in human cells by cyclin A-Cdk2 and cyclin A-Cdk1 complexes. Cell Cycle 2006; 5: 661-666.
    • (2006) Cell Cycle , vol.5 , pp. 661-666
    • Mitra, J.1    Enders, G.H.2    Azizkhan-Clifford, J.3    Lengel, K.L.4
  • 41
    • 46449111508 scopus 로고    scopus 로고
    • Defining the role of Emi1 in the DNA replication-segregation cycle
    • Di Fiore B, Pines J. Defining the role of Emi1 in the DNA replication-segregation cycle. Chromosoma 2008; 117: 333-338.
    • (2008) Chromosoma , vol.117 , pp. 333-338
    • Di Fiore, B.1    Pines, J.2
  • 43
    • 10344247126 scopus 로고    scopus 로고
    • Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry
    • DOI 10.1038/nature03023
    • Rape M, Kirschner MW. Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry. Nature 2004; 432: 588-595. (Pubitemid 39626259)
    • (2004) Nature , vol.432 , Issue.7017 , pp. 588-595
    • Rape, M.1    Kirschner, M.W.2
  • 44
    • 0035890165 scopus 로고    scopus 로고
    • 2 checkpoint in vertebrate cells
    • DOI 10.1093/emboj/20.22.6499
    • Sudo T, Ota Y, Kotani S, Nakao M, Takami Y, Takeda S et al. Activation of Cdh1- dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells. EMBO J 2001; 20: 6499-6508. (Pubitemid 33078722)
    • (2001) EMBO Journal , vol.20 , Issue.22 , pp. 6499-6508
    • Sudo, T.1    Ota, Y.2    Kotani, S.3    Nakao, M.4    Takami, Y.5    Takeda, S.6    Saya, H.7
  • 45
    • 47549098471 scopus 로고    scopus 로고
    • The Cdc14B-Cdh1-Plk1 Axis Controls the G2 DNA-Damage-Response Checkpoint
    • DOI 10.1016/j.cell.2008.05.043, PII S009286740800706X
    • Bassermann F, Frescas D, Guardavaccaro D, Busino L, Peschiaroli A, Pagano M. The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint. Cell 2008; 134: 256-267. (Pubitemid 352010329)
    • (2008) Cell , vol.134 , Issue.2 , pp. 256-267
    • Bassermann, F.1    Frescas, D.2    Guardavaccaro, D.3    Busino, L.4    Peschiaroli, A.5    Pagano, M.6
  • 47
    • 33749246225 scopus 로고    scopus 로고
    • Polo-like Kinase-1 Controls Proteasome-Dependent Degradation of Claspin during Checkpoint Recovery
    • DOI 10.1016/j.cub.2006.08.026, PII S0960982206020367
    • Mamely I, van Vugt MA, Smits VA, Semple JI, Lemmens B, Perrakis A et al. Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery. Curr Biol 2006; 16: 1950-1955. (Pubitemid 44486756)
    • (2006) Current Biology , vol.16 , Issue.19 , pp. 1950-1955
    • Mamely, I.1    Van Vugt, M.A.2    Smits, V.A.3    Semple, J.I.4    Lemmens, B.5    Perrakis, A.6    Medema, R.H.7    Freire, R.8
  • 48
    • 33746429958 scopus 로고    scopus 로고
    • βTrCP Restrains Chk1 Activation and Facilitates Recovery from Genotoxic Stress
    • DOI 10.1016/j.molcel.2006.06.016, PII S109727650600431X
    • Mailand N, Bekker-Jensen S, Bartek J, Lukas J. Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress. Mol Cell 2006; 23: 307-318. (Pubitemid 44128852)
    • (2006) Molecular Cell , vol.23 , Issue.3 , pp. 307-318
    • Mailand, N.1    Bekker-Jensen, S.2    Bartek, J.3    Lukas, J.4
  • 49
    • 33746413746 scopus 로고    scopus 로고
    • βTrCP-Mediated Degradation of Claspin Regulates Recovery from the DNA Replication Checkpoint Response
    • DOI 10.1016/j.molcel.2006.06.013, PII S109727650600428X
    • Peschiaroli A, Dorrello NV, Guardavaccaro D, Venere M, Halazonetis T, Sherman NE et al. SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Mol Cell 2006; 23: 319-329. (Pubitemid 44128849)
    • (2006) Molecular Cell , vol.23 , Issue.3 , pp. 319-329
    • Peschiaroli, A.1    Dorrello, N.V.2    Guardavaccaro, D.3    Venere, M.4    Halazonetis, T.5    Sherman, N.E.6    Pagano, M.7
  • 51
    • 46449119239 scopus 로고    scopus 로고
    • Cdh1: A master G0/G1 regulator
    • DOI 10.1038/ncb0708-755, PII NCB0708-755
    • Skaar JR, Pagano M. Cdh1: a master G0/G1 regulator. Nat Cell Biol 2008; 10: 755-757. (Pubitemid 351927702)
    • (2008) Nature Cell Biology , vol.10 , Issue.7 , pp. 755-757
    • Skaar, J.R.1    Pagano, M.2
  • 52
    • 10944240060 scopus 로고    scopus 로고
    • Closing mitosis: The functions of the Cdc14 phosphatase and its regulation
    • DOI 10.1146/annurev.genet.38.072902.093051
    • Stegmeier F, Amon A. Closing mitosis: the functions of the Cdc14 phosphatase and its regulation. Annu Rev Genet 2004; 38: 203-232. (Pubitemid 40013728)
    • (2004) Annual Review of Genetics , vol.38 , pp. 203-232
    • Stegmeier, F.1    Amon, A.2
  • 53
    • 7544240594 scopus 로고    scopus 로고
    • At the interface between signaling and executing anaphase - Cdc14 and the FEAR network
    • DOI 10.1101/gad.1247304
    • D'mours D, Amon A. At the interface between signaling and executing anaphase-Cdc14 and the FEAR network. Genes Dev 2004; 18: 2581-2595. (Pubitemid 39453097)
    • (2004) Genes and Development , vol.18 , Issue.21 , pp. 2581-2595
    • D'Amours, D.1    Amon, A.2
  • 54
  • 55
    • 65249099623 scopus 로고    scopus 로고
    • DNA damage triggers p21WAF1- dependent Emi1 down-regulation that maintains G2 arrest
    • Lee J, Kim JA, Barbier V, Fotedar A, Fotedar R. DNA damage triggers p21WAF1- dependent Emi1 down-regulation that maintains G2 arrest. Mol Biol Cell 2009; 20: 1891-1902.
    • (2009) Mol Biol Cell , vol.20 , pp. 1891-1902
    • Lee, J.1    Kim, J.A.2    Barbier, V.3    Fotedar, A.4    Fotedar, R.5
  • 56
    • 52449114574 scopus 로고    scopus 로고
    • Ataxia-telangiectasia: From a rare disorder to a paradigm for cell signalling and cancer
    • Lavin MF. Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer. Nat Rev Mol Cell Biol 2008; 9: 759-769.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 759-769
    • Lavin, M.F.1
  • 57
    • 67650500593 scopus 로고    scopus 로고
    • The genetic and molecular basis of Fanconi anemia
    • de Winter JP, Joenje H. The genetic and molecular basis of Fanconi anemia. Mutat Res 2009; 668: 11-19.
    • (2009) Mutat Res , vol.668 , pp. 11-19
    • De Winter, J.P.1    Joenje, H.2
  • 58
    • 61849128915 scopus 로고    scopus 로고
    • Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis
    • Kee Y, Kim JM, D'ndrea A. Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. Genes Dev 2009; 23: 555-560.
    • (2009) Genes Dev , vol.23 , pp. 555-560
    • Kee, Y.1    Kim, J.M.2    D'Ndrea, A.3
  • 60
    • 38149094169 scopus 로고    scopus 로고
    • APC/C-Cdh1- mediated degradation of the Polo kinase Cdc5 promotes the return of Cdc14 into the nucleolus
    • Visintin C, Tomson BN, Rahal R, Paulson J, Cohen M, Taunton J et al. APC/C-Cdh1- mediated degradation of the Polo kinase Cdc5 promotes the return of Cdc14 into the nucleolus. Genes Dev 2008; 22: 79-90.
    • (2008) Genes Dev , vol.22 , pp. 79-90
    • Visintin, C.1    Tomson, B.N.2    Rahal, R.3    Paulson, J.4    Cohen, M.5    Taunton, J.6
  • 63
    • 9644268864 scopus 로고    scopus 로고
    • Mechanism and function of deubiquitinating enzymes
    • DOI 10.1016/j.bbamcr.2004.10.003, PII S0167488904002538, The Ubiquitin-Proteasome System
    • Amerik AY, Hochstrasser M. Mechanism and function of deubiquitinating enzymes. Biochim Biophys Acta 2004; 1695: 189-207. (Pubitemid 39574973)
    • (2004) Biochimica et Biophysica Acta - Molecular Cell Research , vol.1695 , Issue.1-3 , pp. 189-207
    • Amerik, A.Y.1    Hochstrasser, M.2
  • 65
    • 41549142601 scopus 로고    scopus 로고
    • Reverse the curse - The role of deubiquitination in cell cycle control
    • Song L, Rape M. Reverse the curse-the role of deubiquitination in cell cycle control. Curr Opin Cell Biol 2008; 20: 156-163.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 156-163
    • Song, L.1    Rape, M.2
  • 68
    • 59849116083 scopus 로고    scopus 로고
    • USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin
    • Faustrup H, Bekker-Jensen S, Bartek J, Lukas J, Mailand N. USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin. J Cell Biol 2009; 184: 13-19.
    • (2009) J Cell Biol , vol.184 , pp. 13-19
    • Faustrup, H.1    Bekker-Jensen, S.2    Bartek, J.3    Lukas, J.4    Mailand, N.5
  • 69
    • 33746766974 scopus 로고    scopus 로고
    • A Role for the Deubiquitinating Enzyme USP28 in Control of the DNA-Damage Response
    • DOI 10.1016/j.cell.2006.06.039, PII S0092867406008993
    • Zhang D, Zaugg K, Mak TW, Elledge SJ. A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response. Cell 2006; 126: 529-542. (Pubitemid 44163600)
    • (2006) Cell , vol.126 , Issue.3 , pp. 529-542
    • Zhang, D.1    Zaugg, K.2    Mak, T.W.3    Elledge, S.J.4
  • 70
    • 1842421376 scopus 로고    scopus 로고
    • A dynamic role of HAUSP in the p53-Mdm2 pathway
    • DOI 10.1016/S1097-2765(04)00157-1, PII S1097276504001571
    • Li M, Brooks CL, Kon N, Gu W. A dynamic role of HAUSP in the p53-Mdm2 pathway. Mol Cell 2004; 13: 879-886. (Pubitemid 38438482)
    • (2004) Molecular Cell , vol.13 , Issue.6 , pp. 879-886
    • Li, M.1    Brooks, C.L.2    Kon, N.3    Gu, W.4
  • 73
    • 35848942129 scopus 로고    scopus 로고
    • Fbw7 and Usp28 regulate Myc protein stability in response to DNA damage
    • Popov N, Herold S, Llamazares M, Schulein C, Eilers M. Fbw7 and Usp28 regulate myc protein stability in response to DNA damage. Cell Cycle 2007; 6: 2327-2331. (Pubitemid 350058681)
    • (2007) Cell Cycle , vol.6 , Issue.19 , pp. 2327-2331
    • Popov, N.1    Herold, S.2    Llamazares, M.3    Schulein, C.4    Eilers, M.5
  • 75
    • 1542725073 scopus 로고    scopus 로고
    • Targeting the checkpoint kinases: Chemosensitization versus chemoprotection
    • Zhou BB, Bartek J. Targeting the checkpoint kinases: chemosensitization versus chemoprotection. Nat Rev Cancer 2004; 4: 216-225. (Pubitemid 38337501)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.3 , pp. 216-225
    • Zhou, B.-B.S.1    Bartek, J.2
  • 76
    • 33645316142 scopus 로고    scopus 로고
    • Targeting polo-like kinase 1 for cancer therapy
    • Strebhardt K, Ullrich A. Targeting polo-like kinase 1 for cancer therapy. Nat Rev Cancer 2006; 6: 321-330.
    • (2006) Nat Rev Cancer , vol.6 , pp. 321-330
    • Strebhardt, K.1    Ullrich, A.2
  • 77
    • 70149106223 scopus 로고    scopus 로고
    • Polo-like kinase 1 is over-expressed in acute myeloid leukemia and its inhibition preferentially targets the proliferation of leukemic cells
    • Renner AG, Dos Santos C, Recher C, Bailly C, Creancier L, Kruczynski A et al. Polo-like kinase 1 is over-expressed in acute myeloid leukemia and its inhibition preferentially targets the proliferation of leukemic cells. Blood 2009; 114: 659-662.
    • (2009) Blood , vol.114 , pp. 659-662
    • Renner, A.G.1    Dos Santos, C.2    Recher, C.3    Bailly, C.4    Creancier, L.5    Kruczynski, A.6
  • 79
  • 80
    • 38449110015 scopus 로고    scopus 로고
    • Wrenches in the works: Drug discovery targeting the SCF ubiquitin ligase and APC/C complexes
    • Cardozo T, Pagano M. Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes. BMC Biochem 2007; 8 (Suppl 1): S9.
    • (2007) BMC Biochem , vol.8 , Issue.SUPPL. 1
    • Cardozo, T.1    Pagano, M.2


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