-
1
-
-
38649088879
-
Cellular responses to hyperthermia (40-46°C): Cell killing and molecular events
-
Roti Roti JL (2008) Cellular responses to hyperthermia (40-46°C): Cell killing and molecular events. Int J Hyperthermia 24: 3-15.
-
(2008)
Int J Hyperthermia
, vol.24
, pp. 3-15
-
-
Roti Roti, J.L.1
-
3
-
-
0034815317
-
Heat-induced p53-dependent signal transduction and its role in hyperthermic cancer therapy
-
Ohnishi K and Ohnishi T (2001) Heat-induced p53-dependent signal transduction and its role in hyperthermic cancer therapy. Int J Hyperthermia 17: 415-427.
-
(2001)
Int J Hyperthermia
, vol.17
, pp. 415-427
-
-
Ohnishi, K.1
Ohnishi, T.2
-
4
-
-
10844286478
-
Evidence for the involvement of double-strand breaks in heat-induced cell killing
-
Takahashi A, et al (2004) Evidence for the involvement of double-strand breaks in heat-induced cell killing. Cancer Res 64: 8839-8845.
-
(2004)
Cancer Res
, vol.64
, pp. 8839-8845
-
-
Takahashi, A.1
-
5
-
-
13744252931
-
Heat shock induces phosphorylation of histone H2AX in mammalian cells
-
Kaneko H, et al (2005) Heat shock induces phosphorylation of histone H2AX in mammalian cells. Biochem Biophys Res Commun 328: 1101-1106.
-
(2005)
Biochem Biophys Res Commun
, vol.328
, pp. 1101-1106
-
-
Kaneko, H.1
-
6
-
-
34248158282
-
Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status
-
Hunt CR, et al (2007) Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status. Cancer Res 67: 3010-3017.
-
(2007)
Cancer Res
, vol.67
, pp. 3010-3017
-
-
Hunt, C.R.1
-
7
-
-
53249128842
-
Heat induces γH2AX foci formation in mammalian cells
-
Takahashi A, et al (2008) Heat induces γH2AX foci formation in mammalian cells. Mutat Res 656: 88-92.
-
(2008)
Mutat Res
, vol.656
, pp. 88-92
-
-
Takahashi, A.1
-
8
-
-
0036789173
-
125IdU-induced DNA double-strand breaks with gamma-H2AX antibody
-
125IdU-induced DNA double-strand breaks with gamma-H2AX antibody. Radiat Res 158: 486-492.
-
(2002)
Radiat Res
, vol.158
, pp. 486-492
-
-
Sedelnikova, O.A.1
-
9
-
-
0037884963
-
Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses
-
Rothkamm K and Löbrich M (2003) Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc Natl Acad Sci USA 100: 5057-5062.
-
(2003)
Proc Natl Acad Sci Usa
, vol.100
, pp. 5057-5062
-
-
Rothkamm, K.1
Löbrich, M.2
-
10
-
-
26444553297
-
Does γH2AX focus formation depend on the presence of DNA double strand breaks?
-
Takahashi A and Ohnishi T (2005) Does γH2AX focus formation depend on the presence of DNA double strand breaks? Cancer Lett 229: 171-179.
-
(2005)
Cancer Lett
, vol.229
, pp. 171-179
-
-
Takahashi, A.1
Ohnishi, T.2
-
11
-
-
0037085734
-
Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA
-
Bruskov VI, et al (2002) Heat-induced formation of reactive oxygen species and 8-oxoguanine, a biomarker of damage to DNA. Nucleic Acids Res. 30: 1354-1363.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 1354-1363
-
-
Bruskov, V.I.1
-
12
-
-
0028067242
-
Hyperthermia stimulates nitric oxide formation: Electron paramagnetic resonance detection of. NO-heme in blood
-
Hall DM, et al (1994) Hyperthermia stimulates nitric oxide formation: electron paramagnetic resonance detection of. NO-heme in blood. J Appl Physiol 77: 548-553.
-
(1994)
J Appl Physiol
, vol.77
, pp. 548-553
-
-
Hall, D.M.1
-
13
-
-
43649100745
-
Development of thermotolerance requires interaction between polymerase-β and heat shock proteins
-
Takahashi A, et al (2008) Development of thermotolerance requires interaction between polymerase-β and heat shock proteins. Cancer Sci 99: 973-978.
-
(2008)
Cancer Sci
, vol.99
, pp. 973-978
-
-
Takahashi, A.1
-
14
-
-
28544446812
-
DNA double strand breaks do not play a role in heat-induced cell killing
-
Kampinga HH and Laszlo A (2005) DNA double strand breaks do not play a role in heat-induced cell killing. Cancer Res 65: 10632-10633.
-
(2005)
Cancer Res
, vol.65
, pp. 10632-10633
-
-
Kampinga, H.H.1
Laszlo, A.2
-
15
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull TT, et al (2000) A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 10: 886-895.
-
(2000)
Curr Biol
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
-
16
-
-
0035808385
-
The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50-hMRE11-NBS1 complex DNA repair activity
-
Tauchi H, et al (2001) The forkhead-associated domain of NBS1 is essential for nuclear foci formation after irradiation but not essential for hRAD50-hMRE11-NBS1 complex DNA repair activity. J Biol Chem 276: 12-15.
-
(2001)
J Biol Chem
, vol.276
, pp. 12-15
-
-
Tauchi, H.1
-
17
-
-
1842421286
-
Intracellular redistribution and modification of proteins of the Mre11/Rad50/Nbs1 DNA repair complex following irradiation and heat-shock
-
Seno JD and Dynlacht JR (2004) Intracellular redistribution and modification of proteins of the Mre11/Rad50/Nbs1 DNA repair complex following irradiation and heat-shock. J Cell Physiol 199: 157-170.
-
(2004)
J Cell Physiol
, vol.199
, pp. 157-170
-
-
Seno, J.D.1
Dynlacht, J.R.2
-
18
-
-
1842525150
-
Effects of heat shock on the Mre11/ Rad50/Nbs1 complex in irradiated or unirradiated cells
-
Dynlacht JR, et al (2004) Effects of heat shock on the Mre11/ Rad50/Nbs1 complex in irradiated or unirradiated cells. Int J Hyperthermia 20: 144-156.
-
(2004)
Int J Hyperthermia
, vol.20
, pp. 144-156
-
-
Dynlacht, J.R.1
-
19
-
-
57349117060
-
DNA damage recognition proteins localize along heavy ion induced tracks in the cell nucleus
-
Takahashi A, et al (2008) DNA damage recognition proteins localize along heavy ion induced tracks in the cell nucleus. J Radiat Res (Tokyo) 49: 645-652.
-
(2008)
J Radiat Res (tokyo)
, vol.49
, pp. 645-652
-
-
Takahashi, A.1
-
20
-
-
33847737716
-
DNA damage checkpoints: From initiation to recovery or adaptation
-
Bartek J and Lukas J (2007) DNA damage checkpoints: from initiation to recovery or adaptation. Curr Opin Cell Biol 19: 238-245.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 238-245
-
-
Bartek, J.1
Lukas, J.2
-
21
-
-
0030764691
-
hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks
-
Maser RS, et al (1997) hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks. Mol Cell Biol 17: 6087-6096.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6087-6096
-
-
Maser, R.S.1
-
22
-
-
3242880238
-
H2AX: The histone guardian of the genome
-
Fernandez-Capetillo O, et al (2004) H2AX: the histone guardian of the genome. DNA Repair 3: 959-967.
-
(2004)
Dna Repair
, vol.3
, pp. 959-967
-
-
Fernandez-Capetillo, O.1
-
23
-
-
33646117239
-
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
-
Bekker-Jensen S, et al (2006) Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J Cell Biol 173: 195-206.
-
(2006)
J Cell Biol
, vol.173
, pp. 195-206
-
-
Bekker-Jensen, S.1
-
24
-
-
1942538492
-
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
-
Stiff T, et al (2004) ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res 64: 2390-2396.
-
(2004)
Cancer Res
, vol.64
, pp. 2390-2396
-
-
Stiff, T.1
-
25
-
-
25444465151
-
Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the γ-H2AX histone tail
-
Lee MS, et al (2005) Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the γ-H2AX histone tail. J Biol Chem 280: 32053-32056.
-
(2005)
J Biol Chem
, vol.280
, pp. 32053-32056
-
-
Lee, M.S.1
-
26
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
Stucki M, et al (2005) MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 123: 1213-1226.
-
(2005)
Cell
, vol.123
, pp. 1213-1226
-
-
Stucki, M.1
-
27
-
-
0032562595
-
In situ visualization of DNA double-strand break repair in human fibroblasts
-
Nelms BE, et al (1998) In situ visualization of DNA double-strand break repair in human fibroblasts. Science 280: 590-592.
-
(1998)
Science
, vol.280
, pp. 590-592
-
-
Nelms, B.E.1
-
28
-
-
0037468169
-
MDC1 is required for the intra-S-phase DNA damage checkpoint
-
Goldberg M, et al (2003) MDC1 is required for the intra-S-phase DNA damage checkpoint. Nature 421: 952-956.
-
(2003)
Nature
, vol.421
, pp. 952-956
-
-
Goldberg, M.1
-
29
-
-
0037468232
-
MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways
-
Lou Z, et al (2003) MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways. Nature 421: 957-961.
-
(2003)
Nature
, vol.421
, pp. 957-961
-
-
Lou, Z.1
-
30
-
-
0037468192
-
MDC1 is a mediator of the mammalian DNA damage checkpoint
-
Stewart GS, et al (2003) MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature 421: 961-966.
-
(2003)
Nature
, vol.421
, pp. 961-966
-
-
Stewart, G.S.1
-
31
-
-
33646437364
-
Qualitative and quantitative analysis of phosphorylated ATM foci induced by low-dose ionizing radiation
-
Suzuki K, et al (2006) Qualitative and quantitative analysis of phosphorylated ATM foci induced by low-dose ionizing radiation. Radiat Res 165: 499-504.
-
(2006)
Radiat Res
, vol.165
, pp. 499-504
-
-
Suzuki, K.1
-
32
-
-
0346668366
-
Specific recruitment of human cohesin to laser-induced DNA damage
-
Kim JS, et al (2002) Specific recruitment of human cohesin to laser-induced DNA damage. J Biol Chem 277: 45149-45153.
-
(2002)
J Biol Chem
, vol.277
, pp. 45149-45153
-
-
Kim, J.S.1
-
33
-
-
2942687831
-
Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway
-
Kitagawa R, et al (2004) Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. Genes Dev 18: 1423-1438.
-
(2004)
Genes Dev
, vol.18
, pp. 1423-1438
-
-
Kitagawa, R.1
-
34
-
-
0037341599
-
Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
-
Lukas C, et al (2003) Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nat Cell Biol 5: 255-260.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 255-260
-
-
Lukas, C.1
-
35
-
-
14044258550
-
SMC1 involvement in fragile site expression
-
Musio A, et al (2005) SMC1 involvement in fragile site expression. Hum Mol Genet 14: 525-533.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 525-533
-
-
Musio, A.1
-
36
-
-
33645979960
-
DNA damage evaluated by γH2AX foci formation by a selective group of chemical/physical stressors
-
Zhou C, et al (2006) DNA damage evaluated by γH2AX foci formation by a selective group of chemical/physical stressors. Mutat Res 604: 8-18.
-
(2006)
Mutat Res
, vol.604
, pp. 8-18
-
-
Zhou, C.1
-
37
-
-
33947582985
-
Heat shock does not induce γH2AX foci formation but protects cells from N-methyl-N'-nitro-N-nitrosoguanidine-induced genotoxicity
-
Dong Z, et al (2007) Heat shock does not induce γH2AX foci formation but protects cells from N-methyl-N'-nitro-N-nitrosoguanidine-induced genotoxicity. Mutat Res 629: 40-48.
-
(2007)
Mutat Res
, vol.629
, pp. 40-48
-
-
Dong, Z.1
-
38
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
Bakkenist CJ and Kastan MB (2003) DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421: 499-506.
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
39
-
-
0029082681
-
Analysis by pulsed-field gel electrophoresis of DNA double-strand breaks induced by heat and/or X-irradiation in bulk and replicating DNA of CHO cells
-
Wong RS, et al (1995) Analysis by pulsed-field gel electrophoresis of DNA double-strand breaks induced by heat and/or X-irradiation in bulk and replicating DNA of CHO cells. Int J Radiat Biol 68: 141-152.
-
(1995)
Int J Radiat Biol
, vol.68
, pp. 141-152
-
-
Wong, R.S.1
-
40
-
-
0037034210
-
Activation of ATM and phosphorylation of p53 by heat shock
-
Miyakoda M, et al (2002) Activation of ATM and phosphorylation of p53 by heat shock. Oncogene 21: 1090-1096.
-
(2002)
Oncogene
, vol.21
, pp. 1090-1096
-
-
Miyakoda, M.1
-
41
-
-
15844394846
-
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
-
Falck J, Coates J and Jackson SP (2005) Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature 434: 605-611.
-
(2005)
Nature
, vol.434
, pp. 605-611
-
-
Falck, J.1
Coates, J.2
Jackson, S.P.3
-
42
-
-
33751558799
-
Heat-induced phosphorylation of NBS1 in human skin fibroblast cells
-
Ohnishi K, et al (2006) Heat-induced phosphorylation of NBS1 in human skin fibroblast cells. J Cell Biochem 99: 1642-1650.
-
(2006)
J Cell Biochem
, vol.99
, pp. 1642-1650
-
-
Ohnishi, K.1
-
43
-
-
62449263718
-
Heat-induced perturbations of DNA damage signaling pathways are modulated by molecular chaperones
-
Laszlo A and Fleischer I (2009) Heat-induced perturbations of DNA damage signaling pathways are modulated by molecular chaperones. Cancer Res 69: 2042-2049.
-
(2009)
Cancer Res
, vol.69
, pp. 2042-2049
-
-
Laszlo, A.1
Fleischer, I.2
-
44
-
-
0034655991
-
BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
-
Wang Y, et al (2000) BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures. Genes Dev 14: 927-939.
-
(2000)
Genes Dev
, vol.14
, pp. 927-939
-
-
Wang, Y.1
-
45
-
-
0034951854
-
Translocation of MRE11 from the nucleus to the cytoplasm as a mechanism of radiosensitization by heat
-
Zhu WG, et al (2001) Translocation of MRE11 from the nucleus to the cytoplasm as a mechanism of radiosensitization by heat. Radiat. Res. 156: 95-102.
-
(2001)
Radiat. Res
, vol.156
, pp. 95-102
-
-
Zhu, W.G.1
-
46
-
-
0037427084
-
Role of BRCA1 in heat shock response
-
Xian MY, et al (2003) Role of BRCA1 in heat shock response. Oncogene 22: 10-27.
-
(2003)
Oncogene
, vol.22
, pp. 10-27
-
-
Xian, M.Y.1
-
47
-
-
77049110656
-
The biology of heat-induced DNA double-strand breaks
-
Mori E, Takahashi A and Ohnishi T (2008) The biology of heat-induced DNA double-strand breaks. Thermal Med 24: 39-50.
-
(2008)
Thermal Med
, vol.24
, pp. 39-50
-
-
Mori, E.1
Takahashi, A.2
Ohnishi, T.3
|