-
1
-
-
0026097775
-
Sequence and expression of a cDNA encoding MyD118: A novel myeloid differentiation primary response gene induced by multiple cytokines
-
Abdollahi A, Lord KA, Hoffman-Liebermann B, and Liebermann DA (1991) Sequence and expression of a cDNA encoding MyD118: a novel myeloid differentiation primary response gene induced by multiple cytokines. Oncogene 6:165-167.
-
(1991)
Oncogene
, vol.6
, pp. 165-167
-
-
Abdollahi, A.1
Lord, K.A.2
Hoffman-Liebermann, B.3
Liebermann, D.A.4
-
2
-
-
0036296149
-
Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response
-
Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, and Feingold KR (2002) Reduction in cytochrome P-450 enzyme expression is associated with repression of CAR (constitutive androstane receptor) and PXR (pregnane X receptor) in mouse liver during the acute phase response. Biochem Biophys Res Commun 26:145-149.
-
(2002)
Biochem Biophys Res Commun
, vol.26
, pp. 145-149
-
-
Beigneux, A.P.1
Moser, A.H.2
Shigenaga, J.K.3
Grunfeld, C.4
Feingold, K.R.5
-
3
-
-
30944463481
-
Gadd45b is induced through a CAR-dependent, TNF-independent pathway in murine liver hyperplasia
-
Columbano A, Ledda-Columbano GM, Pibiri M, Cossu C, Menegazzi M, Moore DD, Huang W, Tian J, and Locker J (2005) Gadd45b is induced through a CAR-dependent, TNF-independent pathway in murine liver hyperplasia. Hepatology 42:1118-1126.
-
(2005)
Hepatology
, vol.42
, pp. 1118-1126
-
-
Columbano, A.1
Ledda-Columbano, G.M.2
Pibiri, M.3
Cossu, C.4
Menegazzi, M.5
Moore, D.D.6
Huang, W.7
Tian, J.8
Locker, J.9
-
4
-
-
0035015606
-
Enhancement of N-nitrosodimethylamine-initiated hepatocarcinogenesis by phenytoin in male F344/NCr rats at a dose causing maximal induction of CYP2B
-
Diwan BA, Henneman JR, and Nims RW (2001) Enhancement of N-nitrosodimethylamine-initiated hepatocarcinogenesis by phenytoin in male F344/NCr rats at a dose causing maximal induction of CYP2B. Int J Toxicol 20:81-87.
-
(2001)
Int J Toxicol
, vol.20
, pp. 81-87
-
-
Diwan, B.A.1
Henneman, J.R.2
Nims, R.W.3
-
5
-
-
0030908295
-
Characterization of phenobarbital-responsive enhancer module in mouse P450 Cyp2b10 gene
-
Honkakoski P and Negishi M (1997) Characterization of phenobarbital-responsive enhancer module in mouse P450 Cyp2b10 gene. J Biol Chem 272:14943-14949.
-
(1997)
J Biol Chem
, vol.272
, pp. 14943-14949
-
-
Honkakoski, P.1
Negishi, M.2
-
7
-
-
0031682988
-
-
X receptor heterodimer activates the Phenobarbital-responsive enhancer module of the CYP2B gene
-
X receptor heterodimer activates the Phenobarbital-responsive enhancer module of the CYP2B gene. Mol Cell Biol 18:5652-5658.
-
Mol Cell Biol
, vol.18
, pp. 5652-5658
-
-
-
8
-
-
22344451423
-
Xenobiotic stress induces hepatomegary and liver tumors via the nuclear receptor constitutive androstane receptor
-
Huang H, Zhang J, Washington M, Liu J, Parant JM, Lozano G and Moore DD (2005) Xenobiotic stress induces hepatomegary and liver tumors via the nuclear receptor constitutive androstane receptor. Mol Endocrinol 19:1646-1653.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 1646-1653
-
-
Huang, H.1
Zhang, J.2
Washington, M.3
Liu, J.4
Parant, J.M.5
Lozano, G.6
Moore, D.D.7
-
9
-
-
2442657802
-
The constitutive active/androstane receptor regulates phenytoin induction of CYP2C29
-
Jackson JP, Ferguson SS, Moore R, Negishi M, and Goldstein JA (2004) The constitutive active/androstane receptor regulates phenytoin induction of CYP2C29. Mol Pharmacol 65: 1397-1404.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 1397-1404
-
-
Jackson, J.P.1
Ferguson, S.S.2
Moore, R.3
Negishi, M.4
Goldstein, J.A.5
-
10
-
-
24644488771
-
Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicity
-
Jia Y, Guo GL, Surapureddi S, Sarkar J, Qi C, Guo D, Xia J, Kashireddi P, Yu S, Cho Y-W, et al. (2005) Transcription coactivator peroxisome proliferator-activated receptor-binding protein/mediator 1 deficiency abrogates acetaminophen hepatotoxicity. Proc Natl Acad Sci USA 102:12531- 12536.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 12531-12536
-
-
Jia, Y.1
Guo, G.L.2
Surapureddi, S.3
Sarkar, J.4
Qi, C.5
Guo, D.6
Xia, J.7
Kashireddi, P.8
Yu, S.9
Cho, Y.-W.10
-
11
-
-
0032766430
-
Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene
-
Kawamoto T, Sueyoshi T, Zelko I, Moore M, Washburn K, and Negishi M (1999) Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene. Mol Cell Biol 19:6318-6322.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6318-6322
-
-
Kawamoto, T.1
Sueyoshi, T.2
Zelko, I.3
Moore, M.4
Washburn, K.5
Negishi, M.6
-
12
-
-
22344439421
-
Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor
-
Kobayashi K, Yamanaka Y, Iwazaki N, Nakajo I, Hosokawa M, Negishi M, and Chiba K (2005) Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor. Drug Metab Dispos 33:924-929.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 924-929
-
-
Kobayashi, K.1
Yamanaka, Y.2
Iwazaki, N.3
Nakajo, I.4
Hosokawa, M.5
Negishi, M.6
Chiba, K.7
-
13
-
-
4444246000
-
Nuclear receptors CAR and PXR cross talk with FoxO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes
-
Kodama S, Koike C, Negishi M, and Yamamoto Y (2004) Nuclear receptors CAR and PXR cross talk with FoxO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes. Mol Cell Biol 24:7931-7940.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 7931-7940
-
-
Kodama, S.1
Koike, C.2
Negishi, M.3
Yamamoto, Y.4
-
14
-
-
0035117248
-
Effects of bacterial lipopolysaccharide on phenobarbital-induced CYP2B expression in mice
-
Li-Masters T and Morgan ET (2001) Effects of bacterial lipopolysaccharide on phenobarbital-induced CYP2B expression in mice. Drug Metab Dispos 29:252-257.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 252-257
-
-
Li-Masters, T.1
Morgan, E.T.2
-
15
-
-
18144442435
-
Dual action of oestrogens on the mouse constitutive androstane receptor
-
Mäkinen JM, Reinisalo MK. Niemi KP, Viitala PJ, Jyrkkarinne JH, Chung HO, Pelkone O, and Honkakoski P (2003) Dual action of oestrogens on the mouse constitutive androstane receptor. Biochem J 376:465-472.
-
(2003)
Biochem J
, vol.376
, pp. 465-472
-
-
Mäkinen, J.M.1
Reinisalo, M.K.2
Niemi, K.P.3
Viitala, P.J.4
Jyrkkarinne, J.H.5
Chung, H.O.6
Pelkone, O.7
Honkakoski, P.8
-
16
-
-
0037135532
-
Glucocorticoid receptor-interacting protein 1 mediates ligand-independent nuclear translocation and activation of constitutive androstane receptor in vivo
-
Min GJ, Kemper JK, and Byron Kemper B (2002) Glucocorticoid receptor-interacting protein 1 mediates ligand-independent nuclear translocation and activation of constitutive androstane receptor in vivo. J Biol Chem 277:26356-26363.
-
(2002)
J Biol Chem
, vol.277
, pp. 26356-26363
-
-
Min, G.J.1
Kemper, J.K.2
Byron Kemper, B.3
-
17
-
-
0031409592
-
Regulation of cytochromes P450 during inflammation and Infection
-
Morgan ET (1997) Regulation of cytochromes P450 during inflammation and Infection. Drug Metab Rev 29:1129-1188.
-
(1997)
Drug Metab Rev
, vol.29
, pp. 1129-1188
-
-
Morgan, E.T.1
-
18
-
-
0035310906
-
Xenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1
-
Muangmoonchai R, Smirlis D, Wong SC, Edwards M, Philips IR, and Shephard EA (2001) Xenobiotic induction of cytochrome P450 2B1 (CYP2B1) is mediated by the orphan nuclear receptor constitutive androstane receptor (CAR) and requires steroid co-activator 1 (SRC-1) and the transcription factor Sp1. Biochem J 355:71-78.
-
(2001)
Biochem J
, vol.355
, pp. 71-78
-
-
Muangmoonchai, R.1
Smirlis, D.2
Wong, S.C.3
Edwards, M.4
Philips, I.R.5
Shephard, E.A.6
-
19
-
-
1642602694
-
Gadd45b beta mediates the NF-kappa B suppression of JNK signaling by targeting MEK7/JNKK2
-
Papa S, Zazzeroni F, Bubici C, Jayawardena S, Alvarez K, Matuda S, Nguyen DU, Pham CG, Nelsbach AH, Melis T, et al. (2004) Gadd45b beta mediates the NF-kappa B suppression of JNK signaling by targeting MEK7/JNKK2. Nat Cell Biol 6:146-153.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 146-153
-
-
Papa, S.1
Zazzeroni, F.2
Bubici, C.3
Jayawardena, S.4
Alvarez, K.5
Matuda, S.6
Nguyen, D.U.7
Pham, C.G.8
Nelsbach, A.H.9
Melis, T.10
-
20
-
-
33645116164
-
Cytochrome P450 pharmacogenetics and cancer
-
Rodriguez-Antona C, and Ingelman-Sundberg M (2006) Cytochrome P450 pharmacogenetics and cancer. Oncogene 25:1679-1691.
-
(2006)
Oncogene
, vol.25
, pp. 1679-1691
-
-
Rodriguez-Antona, C.1
Ingelman-Sundberg, M.2
-
21
-
-
0041732079
-
Sustained P450 expression and prodrug activation in bolus cyclophosphamide-treated cultured tumor cells: Impact of prodrug schedule on P450 gene-directed enzyme prodrug therapy
-
Schwartz PS, Chen CS, and Waxman DJ (2003) Sustained P450 expression and prodrug activation in bolus cyclophosphamide-treated cultured tumor cells: impact of prodrug schedule on P450 gene-directed enzyme prodrug therapy. Cancer Gene Ther 10:571-582.
-
(2003)
Cancer Gene Ther
, vol.10
, pp. 571-582
-
-
Schwartz, P.S.1
Chen, C.S.2
Waxman, D.J.3
-
22
-
-
0038514189
-
Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor γ coactivator-1α: A possible link between xenobiotic response and nutritional state
-
Shiraki T, Sakai N, Kanaya E and Jingami H (2003) Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor γ coactivator-1α: a possible link between xenobiotic response and nutritional state. J Biol Chem 278:11344-11350.
-
(2003)
J Biol Chem
, vol.278
, pp. 11344-11350
-
-
Shiraki, T.1
Sakai, N.2
Kanaya, E.3
Jingami, H.4
-
23
-
-
0033525886
-
The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene
-
Sueyoshi T, Kawamoto T, Zelko I, Honkakoski P, and Negishi M (1999) The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene. J Biol Chem 274:6043-6046.
-
(1999)
J Biol Chem
, vol.274
, pp. 6043-6046
-
-
Sueyoshi, T.1
Kawamoto, T.2
Zelko, I.3
Honkakoski, P.4
Negishi, M.5
-
24
-
-
0035038008
-
Phenobarbital response element of cytochrome P450 genes and nuclear receptors
-
Sueyoshi T and Negishi M (2001) Phenobarbital response element of cytochrome P450 genes and nuclear receptors. Annu Rev Pharmacol Toxicol 41:123-143.
-
(2001)
Annu Rev Pharmacol Toxicol
, vol.41
, pp. 123-143
-
-
Sueyoshi, T.1
Negishi, M.2
-
25
-
-
46449086327
-
-
Swales S, Kakizaki S, Yamamoto Y, Inoue K, Kobayashi K, and Negishi M (2005) Novel
-
Swales S, Kakizaki S, Yamamoto Y, Inoue K, Kobayashi K, and Negishi M (2005) Novel
-
-
-
-
26
-
-
13544258619
-
-
CAR-mediated mechanism for synergistic activation of two distinct elements within the human cytochrome P450 2B6 gene in HepG2 cells. J Biol Chem 280:3458-3466
-
CAR-mediated mechanism for synergistic activation of two distinct elements within the human cytochrome P450 2B6 gene in HepG2 cells. J Biol Chem 280:3458-3466.
-
-
-
-
27
-
-
33847024555
-
CAR and PXR: The xenobiotic-sensing receptors
-
Timsit T and Negishi M (2007) CAR and PXR: the xenobiotic-sensing receptors. Steroids 72:231-246.
-
(2007)
Steroids
, vol.72
, pp. 231-246
-
-
Timsit, T.1
Negishi, M.2
-
28
-
-
0036259008
-
Residue threonine 350 confers steroid hormone responsiveness to the mouse nuclear orphan receptor CAR
-
Ueda A, Kakizaki S, Negishi M, and Sueyoshi T (2002) Residue threonine 350 confers steroid hormone responsiveness to the mouse nuclear orphan receptor CAR. Mol Pharmacol 61: 1284-1288.
-
(2002)
Mol Pharmacol
, vol.61
, pp. 1284-1288
-
-
Ueda, A.1
Kakizaki, S.2
Negishi, M.3
Sueyoshi, T.4
-
29
-
-
20544458355
-
Thr176 regulates the activity of the mouse nuclear receptor CAR and is conserved in the NR1I subfamily members PXR and VDR
-
Ueda A, Matsui K, Yamamoto Y, Pedersen LC, Sueyoshi T, and Negishi M (2005) Thr176 regulates the activity of the mouse nuclear receptor CAR and is conserved in the NR1I subfamily members PXR and VDR. Biochem J 388:623-630.
-
(2005)
Biochem J
, vol.388
, pp. 623-630
-
-
Ueda, A.1
Matsui, K.2
Yamamoto, Y.3
Pedersen, L.C.4
Sueyoshi, T.5
Negishi, M.6
-
30
-
-
5644295430
-
The nuclear receptor constitutive/androstane receptor is essential for liver tumor promotion by phenobarbital in mice
-
Yamamoto Y, Moore R, Goldsworthy TL, Negishi M, and Maronpot RR (2004) The nuclear receptor constitutive/androstane receptor is essential for liver tumor promotion by phenobarbital in mice. Cancer Res 64:7197-7200.
-
(2004)
Cancer Res
, vol.64
, pp. 7197-7200
-
-
Yamamoto, Y.1
Moore, R.2
Goldsworthy, T.L.3
Negishi, M.4
Maronpot, R.R.5
-
31
-
-
46449098463
-
-
Zanger UM, Klein K, Saussele T, Blievericht J, Hofmann M, and Schwab M (2007) Polymorphic
-
Zanger UM, Klein K, Saussele T, Blievericht J, Hofmann M, and Schwab M (2007) Polymorphic
-
-
-
-
32
-
-
34548105118
-
-
CYP2B6: molecular mechanisms and emerging clinical significance. Pharmacogenomics 8:743-759.
-
CYP2B6: molecular mechanisms and emerging clinical significance. Pharmacogenomics 8:743-759.
-
-
-
-
33
-
-
20444425287
-
NF-kB and not MAPK signaling pathway regulates GADD45β expression during acute inflammation
-
Zhang N, Ahsan MH, Zhu L, Sambucetti LS, Purchio AF, and West DB (2005) NF-kB and not MAPK signaling pathway regulates GADD45β expression during acute inflammation. J Biol Chem 280:21400-21408.
-
(2005)
J Biol Chem
, vol.280
, pp. 21400-21408
-
-
Zhang, N.1
Ahsan, M.H.2
Zhu, L.3
Sambucetti, L.S.4
Purchio, A.F.5
West, D.B.6
|