-
1
-
-
54549108740
-
Anonymous: Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Anonymous: Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455: 1061-1068, 2008.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
2
-
-
14844289540
-
-
Apic G, Ignjatovic T, Boyer S, Russell RB: Illuminating drug discovery with biological pathways. FEBS Lett 579:1872-1877, 2005.
-
(2005)
FEBS Lett
, vol.579
, pp. 1872-1877
-
-
Apic, G.1
Ignjatovic, T.2
Boyer, S.3
Russell, R.B.4
-
3
-
-
48849097164
-
Quantitative proteomics as a new piece of the systems biology puzzle
-
Bachi A, Bonaldi T: Quantitative proteomics as a new piece of the systems biology puzzle. J Proteomics 71:357-367, 2008.
-
(2008)
J Proteomics
, vol.71
, pp. 357-367
-
-
Bachi, A.1
Bonaldi, T.2
-
4
-
-
28544446014
-
How will RNAi facilitate drug development?
-
Bartz S, Jackson AL: How will RNAi facilitate drug development? Sci STKE 295:pe39, 2005.
-
(2005)
Sci STKE
, vol.295
-
-
Bartz, S.1
Jackson, A.L.2
-
5
-
-
34249903654
-
Optimization procedure for small interfering RNA transfection in a 384-well format
-
Borawski J, Lindeman A, Buxton F, Labow M, Gaither LA: Optimization procedure for small interfering RNA transfection in a 384-well format. J Biomol Screen 12:546-559, 2007.
-
(2007)
J Biomol Screen
, vol.12
, pp. 546-559
-
-
Borawski, J.1
Lindeman, A.2
Buxton, F.3
Labow, M.4
Gaither, L.A.5
-
6
-
-
25444448993
-
Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas
-
Bredel M, Bredel C, Juric D, Harsh GR, Vogel H, Recht LD, et al: Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas. Cancer Res 65:8679-8689, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 8679-8689
-
-
Bredel, M.1
Bredel, C.2
Juric, D.3
Harsh, G.R.4
Vogel, H.5
Recht, L.D.6
-
7
-
-
3242669872
-
Improved statistical methods for hit selection in high-throughput screening
-
Brideau C, Gunter B, Pikounis B, Liaw A: Improved statistical methods for hit selection in high-throughput screening. J Biomol Screen 8:634-647, 2003.
-
(2003)
J Biomol Screen
, vol.8
, pp. 634-647
-
-
Brideau, C.1
Gunter, B.2
Pikounis, B.3
Liaw, A.4
-
8
-
-
17244375049
-
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
-
Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, et al: Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature 434: 913-917, 2005.
-
(2005)
Nature
, vol.434
, pp. 913-917
-
-
Bryant, H.E.1
Schultz, N.2
Thomas, H.D.3
Parker, K.M.4
Flower, D.5
Lopez, E.6
-
9
-
-
27144509163
-
A network-based analysis of systemic inflammation in humans
-
Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ, et al: A network-based analysis of systemic inflammation in humans. Nature 437:1032-1037, 2005.
-
(2005)
Nature
, vol.437
, pp. 1032-1037
-
-
Calvano, S.E.1
Xiao, W.2
Richards, D.R.3
Felciano, R.M.4
Baker, H.V.5
Cho, R.J.6
-
10
-
-
39049097168
-
Median absolute deviation to improve hit selection for genome-scale RNAi screens
-
Chung N, Zhang XD, Kreamer A, Locco L, Kuan PF, Bartz S, et al: Median absolute deviation to improve hit selection for genome-scale RNAi screens. J Biomol Screen 13:149-158, 2008.
-
(2008)
J Biomol Screen
, vol.13
, pp. 149-158
-
-
Chung, N.1
Zhang, X.D.2
Kreamer, A.3
Locco, L.4
Kuan, P.F.5
Bartz, S.6
-
11
-
-
33644849221
-
A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase
-
Collins CS, Hong J, Sapinoso L, Zhou Y, Liu Z, Micklash K, et al: A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase. Proc Natl Acad Sci U S A 103:3775-3780, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3775-3780
-
-
Collins, C.S.1
Hong, J.2
Sapinoso, L.3
Zhou, Y.4
Liu, Z.5
Micklash, K.6
-
12
-
-
70349322717
-
Statistics and decision making in high-throughput screening
-
Coma I, Herranz J, Martin J: Statistics and decision making in high-throughput screening. Methods Mol Biol 565:69-106, 2009.
-
(2009)
Methods Mol Biol
, vol.565
, pp. 69-106
-
-
Coma, I.1
Herranz, J.2
Martin, J.3
-
13
-
-
34547771661
-
Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks
-
Daraselia N, Yuryev A, Egorov S, Mazo I, Ispolatov I: Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks. BMC Bioinformatics 8:243, 2007.
-
(2007)
BMC Bioinformatics
, vol.8
, pp. 243
-
-
Daraselia, N.1
Yuryev, A.2
Egorov, S.3
Mazo, I.4
Ispolatov, I.5
-
14
-
-
65549138481
-
Identifying disease-specific genes based on their topological significance in protein networks
-
Dezso Z, Nikolsky Y, Nikolskaya T, Miller J, Cherba D, Webb C, et al: Identifying disease-specific genes based on their topological significance in protein networks. BMC Syst Biol 3:36, 2009.
-
(2009)
BMC Syst Biol
, vol.3
, pp. 36
-
-
Dezso, Z.1
Nikolsky, Y.2
Nikolskaya, T.3
Miller, J.4
Cherba, D.5
Webb, C.6
-
15
-
-
17244373777
-
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
-
Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, et al: Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 434:917-921, 2005.
-
(2005)
Nature
, vol.434
, pp. 917-921
-
-
Farmer, H.1
McCabe, N.2
Lord, C.J.3
Tutt, A.N.4
Johnson, D.A.5
Richardson, T.B.6
-
16
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
Fong PC, Boss DS, Yap TA, Tutt A, Wu P, Mergui-Roelvink M, et al: Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 361:123-134, 2009.
-
(2009)
N Engl J Med
, vol.361
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
Tutt, A.4
Wu, P.5
Mergui-Roelvink, M.6
-
18
-
-
58149142955
-
Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells
-
Ganesan AK, Ho H, Bodemann B, Petersen S, Aruri J, Koshy S, et al: Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells. PLoS Genet 4:e1000298, 2008.
-
(2008)
PLoS Genet
, vol.4
-
-
Ganesan, A.K.1
Ho, H.2
Bodemann, B.3
Petersen, S.4
Aruri, J.5
Koshy, S.6
-
19
-
-
33750114423
-
Probing the human kinome for kinases involved in pancreatic cancer cell survival and gemcitabine resistance
-
Giroux V, Iovanna J, Dagorn JC: Probing the human kinome for kinases involved in pancreatic cancer cell survival and gemcitabine resistance. FASEB J 20:1982-1991, 2006.
-
(2006)
FASEB J
, vol.20
, pp. 1982-1991
-
-
Giroux, V.1
Iovanna, J.2
Dagorn, J.C.3
-
20
-
-
55749101028
-
A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene
-
Gobeil S, Zhu X, Doillon CJ, Green MR: A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene. Genes Dev 22:2932-2940, 2008.
-
(2008)
Genes Dev
, vol.22
, pp. 2932-2940
-
-
Gobeil, S.1
Zhu, X.2
Doillon, C.J.3
Green, M.R.4
-
21
-
-
37349042181
-
Computational methods for analysis of cellular functions and pathways collectively targeted by differentially expressed microRNA
-
Gusev Y: Computational methods for analysis of cellular functions and pathways collectively targeted by differentially expressed microRNA. Methods 44:61-72, 2008.
-
(2008)
Methods
, vol.44
, pp. 61-72
-
-
Gusev, Y.1
-
22
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA: The hallmarks of cancer. Cell 100:57-70, 2000.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
25
-
-
33751208636
-
Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target
-
Horvath S, Zhang B, Carlson M, Lu KV, Zhu S, Felciano RM, et al: Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target. Proc Natl Acad Sci U S A 103:17402-17407, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 17402-17407
-
-
Horvath, S.1
Zhang, B.2
Carlson, M.3
Lu, K.V.4
Zhu, S.5
Felciano, R.M.6
-
26
-
-
64349096829
-
A genomewide RNAi screen identifies a new transcriptional module required for self-renewal
-
Hu G, Kim J, Xu Q, Leng Y, Orkin SH, Elledge SJ: A genomewide RNAi screen identifies a new transcriptional module required for self-renewal. Genes Dev 23:837-848, 2009.
-
(2009)
Genes Dev
, vol.23
, pp. 837-848
-
-
Hu, G.1
Kim, J.2
Xu, Q.3
Leng, Y.4
Orkin, S.H.5
Elledge, S.J.6
-
27
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang DW, Sherman BT, Lempicki RA: Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4:44-57, 2008.
-
(2008)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang, D.W.1
Sherman, B.T.2
Lempicki, R.A.3
-
28
-
-
67650476607
-
Synthetic lethality-a new direction in cancer-drug development
-
Iglehart JD, Silver DP: Synthetic lethality-a new direction in cancer-drug development. N Engl J Med 361:189-191, 2009.
-
(2009)
N Engl J Med
, vol.361
, pp. 189-191
-
-
Iglehart, J.D.1
Silver, D.P.2
-
30
-
-
34347391035
-
Utilizing RNA interference to enhance cancer drug discovery
-
Iorns E, Lord CJ, Turner N, Ashworth A: Utilizing RNA interference to enhance cancer drug discovery. Nat Rev Drug Discov 6:556-568, 2007.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 556-568
-
-
Iorns, E.1
Lord, C.J.2
Turner, N.3
Ashworth, A.4
-
31
-
-
25444497278
-
The concept of synthetic lethality in the context of anticancer therapy
-
Kaelin WG Jr: The concept of synthetic lethality in the context of anticancer therapy. Nat Rev Cancer 5:689-698, 2005.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 689-698
-
-
Kaelin W.G., Jr.1
-
32
-
-
0037805576
-
The KEGG database
-
244-252
-
Kanehisa M: The KEGG database. Novartis Found Symp 247: 91-103, 119-128, 244-252, 2002.
-
(2002)
Novartis Found Symp
, vol.247
, Issue.91-103
, pp. 119-128
-
-
Kanehisa, M.1
-
33
-
-
25444482662
-
Functional genomic analysis of cell division by endoribonuclease-prepared siRNAs
-
Kittler R, Buchholz F: Functional genomic analysis of cell division by endoribonuclease-prepared siRNAs. Cell Cycle 4:564-567, 2005.
-
(2005)
Cell Cycle
, vol.4
, pp. 564-567
-
-
Kittler, R.1
Buchholz, F.2
-
34
-
-
52949083619
-
A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans
-
Kuwahara T, Koyama A, Koyama S, Yoshina S, Ren CH, Kato T, et al: A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans. Hum Mol Genet 17:2997-3009, 2008.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 2997-3009
-
-
Kuwahara, T.1
Koyama, A.2
Koyama, S.3
Yoshina, S.4
Ren, C.H.5
Kato, T.6
-
35
-
-
33749335282
-
The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease
-
Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ, et al: The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease. Science 313:1929-1935, 2006.
-
(2006)
Science
, vol.313
, pp. 1929-1935
-
-
Lamb, J.1
Crawford, E.D.2
Peck, D.3
Modell, J.W.4
Blat, I.C.5
Wrobel, M.J.6
-
36
-
-
56049114215
-
S-adenosylhomocysteine hydrolase downregulation contributes to tumorigenesis
-
Leal JF, Ferrer I, Blanco-Aparicio C, Hernández-Losa J, Ramón Y Cajal S, Carnero A, et al: S-adenosylhomocysteine hydrolase downregulation contributes to tumorigenesis. Carcinogenesis 29:2089-2095, 2008.
-
(2008)
Carcinogenesis
, vol.29
, pp. 2089-2095
-
-
Leal, J.F.1
Ferrer, I.2
Blanco-Aparicio, C.3
Hernández-Losa, J.4
Ramón, Y.5
Cajal, S.6
Carnero, A.7
-
37
-
-
33745679153
-
RNA interference takes flight: a new RNAi screen reveals cell cycle regulators in Drosophila cells
-
Lents NH, Baldassare JJ: RNA interference takes flight: a new RNAi screen reveals cell cycle regulators in Drosophila cells. Trends Endocrinol Metab 17:173-174, 2006.
-
(2006)
Trends Endocrinol Metab
, vol.17
, pp. 173-174
-
-
Lents, N.H.1
Baldassare, J.J.2
-
38
-
-
38049160310
-
Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen
-
Loh SHY, Francescut L, Lingor P, Bähr M, Nicotera P: Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen. Cell Death Differ 15:283-298, 2008.
-
(2008)
Cell Death Differ
, vol.15
, pp. 283-298
-
-
Loh, S.H.Y.1
Francescut, L.2
Lingor, P.3
Bähr, M.4
Nicotera, P.5
-
39
-
-
14844320045
-
Modulation of angiogenesis with siRNA inhibitors for novel therapeutics
-
Lu PY, Xie FY, Woodle MC: Modulation of angiogenesis with siRNA inhibitors for novel therapeutics. Trends Mol Med 11:104-113, 2005.
-
(2005)
Trends Mol Med
, vol.11
, pp. 104-113
-
-
Lu, P.Y.1
Xie, F.Y.2
Woodle, M.C.3
-
40
-
-
66149091940
-
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the ras oncogene
-
Luo J, Emanuele MJ, Li D, Creighton CJ, Schlabach MR, Westbrook TF, et al: A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the ras oncogene. Cell 137:835-848, 2009.
-
(2009)
Cell
, vol.137
, pp. 835-848
-
-
Luo, J.1
Emanuele, M.J.2
Li, D.3
Creighton, C.J.4
Schlabach, M.R.5
Westbrook, T.F.6
-
41
-
-
33845363835
-
A phase I and pharmacologic study of sequences of the proteasome inhibitor, bortezomib (PS-341, Velcade), in combination with paclitaxel and carboplatin in patients with advanced malignancies
-
Ma C, Mandrekar SJ, Alberts SR, Croghan GA, Jatoi A, Reid JM, et al: A phase I and pharmacologic study of sequences of the proteasome inhibitor, bortezomib (PS-341, Velcade), in combination with paclitaxel and carboplatin in patients with advanced malignancies. Cancer Chemother Pharmacol 59: 207-215, 2007.
-
(2007)
Cancer Chemother Pharmacol
, vol.59
, pp. 207-215
-
-
Ma, C.1
Mandrekar, S.J.2
Alberts, S.R.3
Croghan, G.A.4
Jatoi, A.5
Reid, J.M.6
-
42
-
-
20444419344
-
Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
-
MacKeigan JP, Murphy LO, Blenis J: Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat Cell Biol 7:591-600, 2005.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 591-600
-
-
MacKeigan, J.P.1
Murphy, L.O.2
Blenis, J.3
-
43
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
Martinez J, Patkaniowska A, Urlaub H, Lührmann R, Tuschl T: Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110:563-574, 2002.
-
(2002)
Cell
, vol.110
, pp. 563-574
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
Lührmann, R.4
Tuschl, T.5
-
44
-
-
33846067524
-
PANTHER version 6: protein sequence and function evolution data with expanded representation of biological pathways
-
Database issue
-
Mi H, Guo N, Kejariwal A, Thomas PD: PANTHER version 6: protein sequence and function evolution data with expanded representation of biological pathways. Nucleic Acids Res 35 (Database issue):D247-D252, 2007.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Mi, H.1
Guo, N.2
Kejariwal, A.3
Thomas, P.D.4
-
45
-
-
33644752656
-
RNAi-based screening of the human kinome identifies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors
-
Morgan-Lappe S, Woods KW, Li Q, Anderson MG, Schurdak ME, Luo Y, et al: RNAi-based screening of the human kinome identifies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors. Oncogene 25:1340-1348, 2006.
-
(2006)
Oncogene
, vol.25
, pp. 1340-1348
-
-
Morgan-Lappe, S.1
Woods, K.W.2
Li, Q.3
Anderson, M.G.4
Schurdak, M.E.5
Luo, Y.6
-
46
-
-
58149326888
-
Gene profiling and pathway analysis of neuroendocrine transdifferentiated prostate cancer cells
-
Mori R, Xiong S, Wang Q, Tarabolous C, Shimada H, Panteris E, et al: Gene profiling and pathway analysis of neuroendocrine transdifferentiated prostate cancer cells. Prostate 69:12-23, 2009.
-
(2009)
Prostate
, vol.69
, pp. 12-23
-
-
Mori, R.1
Xiong, S.2
Wang, Q.3
Tarabolous, C.4
Shimada, H.5
Panteris, E.6
-
47
-
-
33749537857
-
Genome-wide functional analysis of human cell-cycle regulators
-
Mukherji M, Bell R, Supekova L, Wang Y, Orth AP, Batalov S, et al: Genome-wide functional analysis of human cell-cycle regulators. Proc Natl Acad Sci U S A 103:14819-14824, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14819-14824
-
-
Mukherji, M.1
Bell, R.2
Supekova, L.3
Wang, Y.4
Orth, A.P.5
Batalov, S.6
-
48
-
-
11144346764
-
The promise of genomics to identify novel therapeutic targets
-
Orth AP, Batalov S, Perrone M, Chanda SK: The promise of genomics to identify novel therapeutic targets. Expert Opin Ther Targets 8:587-596, 2004.
-
(2004)
Expert Opin Ther Targets
, vol.8
, pp. 587-596
-
-
Orth, A.P.1
Batalov, S.2
Perrone, M.3
Chanda, S.K.4
-
49
-
-
0035408344
-
Proteasome inhibitor 1 enhances paclitaxel-induced apoptosis in human lung adenocarcinoma cell line
-
Oyaizu H, Adachi Y, Okumura T, Okigaki M, Oyaizu N, Taketani S, et al: Proteasome inhibitor 1 enhances paclitaxel-induced apoptosis in human lung adenocarcinoma cell line. Oncol Rep 8:825-829, 2001.
-
(2001)
Oncol Rep
, vol.8
, pp. 825-829
-
-
Oyaizu, H.1
Adachi, Y.2
Okumura, T.3
Okigaki, M.4
Oyaizu, N.5
Taketani, S.6
-
50
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, Lin JCH, Leary RJ, Angenendt P, et al: An integrated genomic analysis of human glioblastoma multiforme. Science 321:1807-1812, 2008.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.H.4
Leary, R.J.5
Angenendt, P.6
-
51
-
-
77951729368
-
Growth factor signaling pathways and receptor tyrosine kinase inhibitors
-
Newton HB (ed). Philadelphia: Elsevier
-
Pollack I: Growth factor signaling pathways and receptor tyrosine kinase inhibitors, in Newton HB (ed): Handbook of Brain Tumor Chemotherapy. Philadelphia: Elsevier, 2006, pp 155-172.
-
(2006)
Handbook of Brain Tumor Chemotherapy
, pp. 155-172
-
-
Pollack, I.1
-
52
-
-
38449084517
-
Design and implementation of high-throughput RNAi screens in cultured Drosophila cells
-
Ramadan N, Flockhart I, Booker M, Perrimon N, Mathey-Prevot B: Design and implementation of high-throughput RNAi screens in cultured Drosophila cells. Nat Protoc 2:2245-2264, 2007.
-
(2007)
Nat Protoc
, vol.2
, pp. 2245-2264
-
-
Ramadan, N.1
Flockhart, I.2
Booker, M.3
Perrimon, N.4
Mathey-Prevot, B.5
-
53
-
-
34548799835
-
Aberrant constitutive activation of nuclear factor kappaB in glioblastoma multiforme drives invasive phenotype
-
Raychaudhuri B, Han Y, Lu T, Vogelbaum MA: Aberrant constitutive activation of nuclear factor kappaB in glioblastoma multiforme drives invasive phenotype. J Neurooncol 85:39-47, 2007.
-
(2007)
J Neurooncol
, vol.85
, pp. 39-47
-
-
Raychaudhuri, B.1
Han, Y.2
Lu, T.3
Vogelbaum, M.A.4
-
54
-
-
33847246805
-
Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles
-
Rhodes DR, Kalyana-Sundaram S, Mahavisno V, Varambally R, Yu J, Briggs BB, et al: Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia 9:166-180, 2007.
-
(2007)
Neoplasia
, vol.9
, pp. 166-180
-
-
Rhodes, D.R.1
Kalyana-Sundaram, S.2
Mahavisno, V.3
Varambally, R.4
Yu, J.5
Briggs, B.B.6
-
55
-
-
19344375743
-
RNAi therapeutics: how likely, how soon?
-
Robinson R: RNAi therapeutics: how likely, how soon? PLoS Biology 2(1):e28, 2004.
-
(2004)
PLoS Biology
, vol.2
, Issue.1
-
-
Robinson, R.1
-
56
-
-
29144531173
-
The druggable genome: an update
-
Russ AP, Lampel S: The druggable genome: an update. Drug Discov Today 10:1607-1610, 2005.
-
(2005)
Drug Discov Today
, vol.10
, pp. 1607-1610
-
-
Russ, A.P.1
Lampel, S.2
-
57
-
-
9144226019
-
Oncology studies using siRNA libraries: the dawn of RNAi-based genomics
-
Sachse C, Echeverri CJ: Oncology studies using siRNA libraries: the dawn of RNAi-based genomics. Oncogene 23:8384-8391, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 8384-8391
-
-
Sachse, C.1
Echeverri, C.J.2
-
59
-
-
0344875495
-
Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination
-
Schultz N, Lopez E, Saleh-Gohari N, Helleday T: Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination. Nucleic Acids Res 31:4959-4964, 2003.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 4959-4964
-
-
Schultz, N.1
Lopez, E.2
Saleh-Gohari, N.3
Helleday, T.4
-
60
-
-
48249098518
-
Identification of neural outgrowth genes using genomewide RNAi
-
Sepp KJ, Hong P, Lizarraga SB, Liu JS, Mejia LA, Walsh CA, et al: Identification of neural outgrowth genes using genomewide RNAi. PLoS Genet 4:e1000111, 2008.
-
(2008)
PLoS Genet
, vol.4
-
-
Sepp, K.J.1
Hong, P.2
Lizarraga, S.B.3
Liu, J.S.4
Mejia, L.A.5
Walsh, C.A.6
-
61
-
-
0032766223
-
Low dose hypersensitivity in the T98G human glioblastoma cell line
-
Short SMC, Mayes C, Woodcock M, Johns H, Joiner MC: Low dose hypersensitivity in the T98G human glioblastoma cell line. Int J Radiat Biol 75:847-855, 1999.
-
(1999)
Int J Radiat Biol
, vol.75
, pp. 847-855
-
-
Short, S.M.C.1
Mayes, C.2
Woodcock, M.3
Johns, H.4
Joiner, M.C.5
-
62
-
-
0018408665
-
T98G: an anchorage-independent human tumor cell line that exhibits stationary phase G1 arrest in vitro
-
Stein GH: T98G: an anchorage-independent human tumor cell line that exhibits stationary phase G1 arrest in vitro. J Cell Physiol 99:43-54, 1979.
-
(1979)
J Cell Physiol
, vol.99
, pp. 43-54
-
-
Stein, G.H.1
-
63
-
-
62649142784
-
A guide to the integrated application of on-line data mining tools for the inference of gene functions at the systems level
-
Meier S, Gehring C: A guide to the integrated application of on-line data mining tools for the inference of gene functions at the systems level. Biotechnol J 3:1375-1387, 2008.
-
(2008)
Biotechnol J
, vol.3
, pp. 1375-1387
-
-
Meier, S.1
Gehring, C.2
-
64
-
-
38949105541
-
Independent activation of Akt and NF-kappaB pathways and their role in resistance to TNF-alpha mediated cytotoxicity in gliomas
-
Sudheerkumar P, Shiras A, Das G, Jagtap JC, Prasad V, Shastry P: Independent activation of Akt and NF-kappaB pathways and their role in resistance to TNF-alpha mediated cytotoxicity in gliomas. Mol Carcinog 47:126-136, 2008.
-
(2008)
Mol Carcinog
, vol.47
, pp. 126-136
-
-
Sudheerkumar, P.1
Shiras, A.2
Das, G.3
Jagtap, J.C.4
Prasad, V.5
Shastry, P.6
-
65
-
-
61849160363
-
A functional genomic screen identifies cellular cofactors of hepatitis C virus replication
-
Tai AW, Benita Y, Peng LF, Kim SS, Sakamoto N, Xavier RJ, et al: A functional genomic screen identifies cellular cofactors of hepatitis C virus replication. Cell Host Microbe 5: 298-307, 2009.
-
(2009)
Cell Host Microbe
, vol.5
, pp. 298-307
-
-
Tai, A.W.1
Benita, Y.2
Peng, L.F.3
Kim, S.S.4
Sakamoto, N.5
Xavier, R.J.6
-
66
-
-
77951756994
-
Carcinogenesis: balance between apoptosis and survival pathways
-
Srivastava R (ed). Totowa NJ: Humana Press
-
Tang D, Kehrer J: Carcinogenesis: balance between apoptosis and survival pathways, in Srivastava R (ed): Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms. Totowa NJ: Humana Press, 2007, Vol 1.
-
(2007)
Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms
, vol.1
-
-
Tang, D.1
Kehrer, J.2
-
67
-
-
47749089779
-
A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer
-
Tang W, Dodge M, Gundapaneni D, Michnoff C, Roth M, Lum L: A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer. Proc Natl Acad Sci U S A 105:9697-9702, 2008.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9697-9702
-
-
Tang, W.1
Dodge, M.2
Gundapaneni, D.3
Michnoff, C.4
Roth, M.5
Lum, L.6
-
68
-
-
73149111772
-
Identification of Survival Genes in Human Glioblastoma Cells Using siRNA Screening
-
[epub ahead of print]
-
Thaker NG, Zhang F, McDonald PR, Shun TY, Lewen MD, Pollack IF, et al: Identification of Survival Genes in Human Glioblastoma Cells Using siRNA Screening. Mol Pharmacol [epub ahead of print], 2009.
-
(2009)
Mol Pharmacol
-
-
Thaker, N.G.1
Zhang, F.2
McDonald, P.R.3
Shun, T.Y.4
Lewen, M.D.5
Pollack, I.F.6
-
69
-
-
66449112217
-
Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network
-
Tu Z, Argmann C, Wong KK, Mitnaul LJ, Edwards S, Sach IC, et al: Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network. Genome Res 19:1057-1067, 2009.
-
(2009)
Genome Res
, vol.19
, pp. 1057-1067
-
-
Tu, Z.1
Argmann, C.2
Wong, K.K.3
Mitnaul, L.J.4
Edwards, S.5
Sach, I.C.6
-
70
-
-
43249085571
-
A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor
-
Turner NC, Lord CJ, Iorns E, Brough R, Swift S, Elliott R, et al: A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor. EMBO J 27:1368-1377, 2008.
-
(2008)
EMBO J
, vol.27
, pp. 1368-1377
-
-
Turner, N.C.1
Lord, C.J.2
Iorns, E.3
Brough, R.4
Swift, S.5
Elliott, R.6
-
71
-
-
27744577845
-
Cell migration and invasion assays
-
Valster A, Tran NL, Nakada M, Berens ME, Chan AY, Symons M: Cell migration and invasion assays. Methods 37:208-215, 2005.
-
(2005)
Methods
, vol.37
, pp. 208-215
-
-
Valster, A.1
Tran, N.L.2
Nakada, M.3
Berens, M.E.4
Chan, A.Y.5
Symons, M.6
-
72
-
-
58949092362
-
Pathway targets to explore in the treatment of non-small cell lung cancer
-
Weiss GJ, Kingsley C: Pathway targets to explore in the treatment of non-small cell lung cancer. Journal of Thoracic Oncology 3:1342-1352, 2008.
-
(2008)
Journal of Thoracic Oncology
, vol.3
, pp. 1342-1352
-
-
Weiss, G.J.1
Kingsley, C.2
-
73
-
-
0031767393
-
Predicting chemoresistance in human malignant glioma cells: the role of molecular genetic analyses
-
Weller MRJ, Rieger J, Grimmel C, Van Meir EG, De Tribolet N, Krajewski S, et al: Predicting chemoresistance in human malignant glioma cells: the role of molecular genetic analyses. Int J Cancer 79:640-644, 1998.
-
(1998)
Int J Cancer
, vol.79
, pp. 640-644
-
-
Weller, M.R.J.1
Rieger, J.2
Grimmel, C.3
Van Meir, E.G.4
De Tribolet, N.5
Krajewski, S.6
-
74
-
-
20444376939
-
A genetic screen for candidate tumor suppressors identifies REST
-
Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B, et al: A genetic screen for candidate tumor suppressors identifies REST. Cell 121:837-848, 2005.
-
(2005)
Cell
, vol.121
, pp. 837-848
-
-
Westbrook, T.F.1
Martin, E.S.2
Schlabach, M.R.3
Leng, Y.4
Liang, A.C.5
Feng, B.6
-
75
-
-
34147198467
-
Synthetic lethal screen identification of chemosensitizer loci in cancer cells
-
Whitehurst AW, Bodemann BO, Cardenas J, Ferguson D, Girard L, Peyton M, et al: Synthetic lethal screen identification of chemosensitizer loci in cancer cells. Nature 446:815-819, 2007.
-
(2007)
Nature
, vol.446
, pp. 815-819
-
-
Whitehurst, A.W.1
Bodemann, B.O.2
Cardenas, J.3
Ferguson, D.4
Girard, L.5
Peyton, M.6
-
76
-
-
0033003760
-
A simple statistical parameter for use in evaluation and validation of high throughput screening assays
-
Zhang JH, Chung TD, Oldenburg KR: A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 4:67-73, 1999.
-
(1999)
J Biomol Screen
, vol.4
, pp. 67-73
-
-
Zhang, J.H.1
Chung, T.D.2
Oldenburg, K.R.3
-
77
-
-
33846973375
-
Knockdown of mutant Kras expression by adenovirus-mediated siRNA inhibits the in vitro and in vivo growth of lung cancer cells
-
Zhang Z, Jiang G, Yang F, Wang J: Knockdown of mutant Kras expression by adenovirus-mediated siRNA inhibits the in vitro and in vivo growth of lung cancer cells. Cancer Biol Ther 5:1481-1486, 2006.
-
(2006)
Cancer Biol Ther
, vol.5
, pp. 1481-1486
-
-
Zhang, Z.1
Jiang, G.2
Yang, F.3
Wang, J.4
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