Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells

PLoS Genetics

Volumn 4, Issue 12, 2008, Pages

  Ganesan, Anand K ^a   Ho, Hsiang ^a   Bodemann, Brian ^b   Petersen, Sean ^c   Aruri, Jayavani ^a   Koshy, Shiney ^a   Richardson, Zachary ^a   Le, Lu Q ^c   Krasieva, Tatiana ^d   Roth, Michael G ^c   Farmer, Pat ^e   White, Michael A ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; MELANIN; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MONOPHENOL MONOOXYGENASE; PIGMENT; SMALL INTERFERING RNA;

ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BIOGENESIS; BIOSYNTHESIS; FUNCTIONAL GENOMICS; GENE IDENTIFICATION; GENE LIBRARY; GENETIC SCREENING; HUMAN; HUMAN GENOME; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MELANOCYTE; MELANOGENESIS; MELANOMA CELL; MOUSE; MULTIGENE FAMILY; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; RNA INTERFERENCE; SKIN PIGMENTATION; ULTRAVIOLET IRRADIATION; ANIMAL; C57BL MOUSE; CELL LINE; GENETICS; GENOMICS; METABOLISM; SIGNAL TRANSDUCTION; SKIN DISEASE;

ANIMALS; CELL LINE; GENOME, HUMAN; GENOMICS; HUMANS; MELANINS; MELANOCYTES; MICE; MICE, INBRED C57BL; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SKIN DISEASES; SKIN PIGMENTATION;

EID: 58149142955     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000298     Document Type: Article

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