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Volumn 37, Issue 2, 2010, Pages 243-252

ATP-sensitive potassium channels: A promising target for protecting neurovascular unit function in stroke

Author keywords

ATP sensitive potassium channels; Neurovascular unit; Stroke

Indexed keywords

4 AMINOBUTYRIC ACID; 5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) INHIBITOR; ADENOSINE TRIPHOSPHATASE (POTASSIUM); BMS 191095; DIAZOXIDE; EXCITATORY AMINO ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; NEUROPROTECTIVE AGENT; PINACIDIL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 75649145870     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2009.05190.x     Document Type: Review
Times cited : (41)

References (119)
  • 1
    • 33748355616 scopus 로고    scopus 로고
    • Advancing the study of stroke in women: Summary and recommendations for future research from an NINDS-Sponsored Multidisciplinary Working Group
    • Bushnell CD, Hurn P, Colton C et al. Advancing the study of stroke in women: Summary and recommendations for future research from an NINDS-Sponsored Multidisciplinary Working Group. Stroke 2006 37 : 2387 2399.
    • (2006) Stroke , vol.37 , pp. 2387-2399
    • Bushnell, C.D.1    Hurn, P.2    Colton, C.3
  • 2
    • 40349088829 scopus 로고    scopus 로고
    • Pharmacological approaches to acute ischaemic stroke: Reperfusion certainly, neuroprotection possibly
    • Green AR. Pharmacological approaches to acute ischaemic stroke: Reperfusion certainly, neuroprotection possibly. Br. J. Pharmacol. 2008 153 (Suppl. 1 S325 38.
    • (2008) Br. J. Pharmacol. , vol.1531 , pp. 325-38
    • Green, A.R.1
  • 3
    • 33745955359 scopus 로고    scopus 로고
    • Therapeutic strategies for the treatment of stroke
    • Green AR, Shuaib A. Therapeutic strategies for the treatment of stroke. Drug Discov. Today 2006 11 : 681 693.
    • (2006) Drug Discov. Today , vol.11 , pp. 681-693
    • Green, A.R.1    Shuaib, A.2
  • 4
    • 33846694043 scopus 로고    scopus 로고
    • Neurovascular proteases in brain injury, hemorrhage and remodeling after stroke
    • Zhao BQ, Tejima E, Lo EH. Neurovascular proteases in brain injury, hemorrhage and remodeling after stroke. Stroke 2007 38 : 748 752.
    • (2007) Stroke , vol.38 , pp. 748-752
    • Zhao, B.Q.1    Tejima, E.2    Lo, E.H.3
  • 5
    • 33846522259 scopus 로고    scopus 로고
    • Stroke biomarkers: Can they help us to guide stroke thrombolysis?
    • Montaner J. Stroke biomarkers: Can they help us to guide stroke thrombolysis? Drug News Perspect. 2006 19 : 523 532.
    • (2006) Drug News Perspect. , vol.19 , pp. 523-532
    • Montaner, J.1
  • 6
    • 0036209260 scopus 로고    scopus 로고
    • Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release
    • Liu D, Lu C, Wan R, Auyeung WW, Mattson MP. Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release. J. Cereb. Blood Flow Metab. 2002 22 : 431 443.
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , pp. 431-443
    • Liu, D.1    Lu, C.2    Wan, R.3    Auyeung, W.W.4    Mattson, M.P.5
  • 7
    • 10344226664 scopus 로고    scopus 로고
    • Vascular aspects of neuroprotection
    • Takahashi M, Macdonald RL. Vascular aspects of neuroprotection. Neurol. Res. 2004 26 : 862 869.
    • (2004) Neurol. Res. , vol.26 , pp. 862-869
    • Takahashi, M.1    MacDonald, R.L.2
  • 8
    • 33846423878 scopus 로고    scopus 로고
    • Energy metabolism in astrocytes: High rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis
    • Hertz L, Peng L, Dienel GA. Energy metabolism in astrocytes: High rate of oxidative metabolism and spatiotemporal dependence on glycolysis/ glycogenolysis. J. Cereb. Blood Flow Metab. 2007 27 : 219 249.
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 219-249
    • Hertz, L.1    Peng, L.2    Dienel, G.A.3
  • 9
    • 34247148660 scopus 로고    scopus 로고
    • High-resolution in vivo imaging of the neurovascular unit during spreading depression
    • Chuquet J, Hollender L, Nimchinsky EA. High-resolution in vivo imaging of the neurovascular unit during spreading depression. J. Neurosci. 2007 27 : 4036 4044.
    • (2007) J. Neurosci. , vol.27 , pp. 4036-4044
    • Chuquet, J.1    Hollender, L.2    Nimchinsky, E.A.3
  • 10
    • 0346186100 scopus 로고    scopus 로고
    • A key role for TRPM7 channels in anoxic neuronal death
    • Aarts M, Iihara K, Wei WL et al. A key role for TRPM7 channels in anoxic neuronal death. Cell 2003 115 : 863 877.
    • (2003) Cell , vol.115 , pp. 863-877
    • Aarts, M.1    Iihara, K.2    Wei, W.L.3
  • 12
    • 12144271690 scopus 로고    scopus 로고
    • The PSD95-nNOS interface: A target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death
    • Cao J, Viholainen JI, Dart C, Warwick HK, Leyland ML, Courtney MJ. The PSD95-nNOS interface: A target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death. J. Cell Biol. 2005 168 : 117 126.
    • (2005) J. Cell Biol. , vol.168 , pp. 117-126
    • Cao, J.1    Viholainen, J.I.2    Dart, C.3    Warwick, H.K.4    Leyland, M.L.5    Courtney, M.J.6
  • 13
    • 29044445105 scopus 로고    scopus 로고
    • The function and integrity of the neurovascular unit rests upon the integration of the vascular and inflammatory cell systems
    • Han HS, Suk K. The function and integrity of the neurovascular unit rests upon the integration of the vascular and inflammatory cell systems. Curr. Neurovasc. Res. 2005 2 : 409 423.
    • (2005) Curr. Neurovasc. Res. , vol.2 , pp. 409-423
    • Han, H.S.1    Suk, K.2
  • 14
    • 46749099351 scopus 로고    scopus 로고
    • New therapeutic targets in the neurovascular pathway in Alzheimer's disease
    • Zlokovic BV. New therapeutic targets in the neurovascular pathway in Alzheimer's disease. Neurotherapeutics 2008 5 : 409 414.
    • (2008) Neurotherapeutics , vol.5 , pp. 409-414
    • Zlokovic, B.V.1
  • 15
    • 40349085617 scopus 로고    scopus 로고
    • Experimental models, neurovascular mechanisms and translational issues in stroke research
    • Lo EH. Experimental models, neurovascular mechanisms and translational issues in stroke research. Br. J. Pharmacol. 2008 153 (Suppl. 1 S396 405.
    • (2008) Br. J. Pharmacol. , vol.1531 , pp. 396-405
    • Lo, E.H.1
  • 16
    • 35848949798 scopus 로고    scopus 로고
    • Cell-cell signaling in the neurovascular unit
    • Lok J, Gupta P, Guo S et al. Cell-cell signaling in the neurovascular unit. Neurochem. Res. 2007 32 : 2032 2045.
    • (2007) Neurochem. Res. , vol.32 , pp. 2032-2045
    • Lok, J.1    Gupta, P.2    Guo, S.3
  • 17
    • 17344363713 scopus 로고    scopus 로고
    • Cell biology of the neurovascular unit: Implications for drug delivery across the blood-brain barrier
    • McCarty JH. Cell biology of the neurovascular unit: Implications for drug delivery across the blood-brain barrier. Assay Drug Dev. Technol. 2005 3 : 89 95.
    • (2005) Assay Drug Dev. Technol. , vol.3 , pp. 89-95
    • McCarty, J.H.1
  • 19
    • 33847606985 scopus 로고    scopus 로고
    • + channels are redox-sensitive pathways that control reactive oxygen species production
    • + channels are redox-sensitive pathways that control reactive oxygen species production. Free Radic. Biol. Med. 2007 42 : 1039 1048.
    • (2007) Free Radic. Biol. Med. , vol.42 , pp. 1039-1048
    • Facundo, H.T.1    De Paula, J.G.2    Kowaltowski, A.J.3
  • 20
    • 0029951630 scopus 로고    scopus 로고
    • Modulation of GABA transmission by diazoxide and cromakalim in the globus pallidus: Implications for the treatment of Parkinson's disease
    • Maneuf YP, Duty S, Hille CJ, Crossman AR, Brotchie JM. Modulation of GABA transmission by diazoxide and cromakalim in the globus pallidus: Implications for the treatment of Parkinson's disease. Exp. Neurol. 1996 139 : 12 16.
    • (1996) Exp. Neurol. , vol.139 , pp. 12-16
    • Maneuf, Y.P.1    Duty, S.2    Hille, C.J.3    Crossman, A.R.4    Brotchie, J.M.5
  • 21
    • 0028902138 scopus 로고
    • Putative pre- and postsynaptic ATP-sensitive potassium channels in the rat substantia nigra in vitro
    • Watts AE, Hicks GA, Henderson G. Putative pre- and postsynaptic ATP-sensitive potassium channels in the rat substantia nigra in vitro. J. Neurosci. 1995 15 : 3065 3074.
    • (1995) J. Neurosci. , vol.15 , pp. 3065-3074
    • Watts, A.E.1    Hicks, G.A.2    Henderson, G.3
  • 23
    • 0030593437 scopus 로고    scopus 로고
    • Electrophysiological investigation of adenosine trisphosphate-sensitive potassium channels in the rat substantia nigra pars reticulata
    • Stanford IM, Lacey MG. Electrophysiological investigation of adenosine trisphosphate-sensitive potassium channels in the rat substantia nigra pars reticulata. Neuroscience 1996 74 : 499 509.
    • (1996) Neuroscience , vol.74 , pp. 499-509
    • Stanford, I.M.1    Lacey, M.G.2
  • 25
    • 34248376872 scopus 로고    scopus 로고
    • Sulfatide increases adiponectin and decreases TNF-alpha, IL-6, and IL-8 in human adipose tissue in vitro
    • Bruun JM, Roeske-Nielsen A, Richelsen B, Fredman P, Buschard K. Sulfatide increases adiponectin and decreases TNF-alpha, IL-6, and IL-8 in human adipose tissue in vitro. Mol. Cell. Endocrinol. 2007 263 : 142 148.
    • (2007) Mol. Cell. Endocrinol. , vol.263 , pp. 142-148
    • Bruun, J.M.1    Roeske-Nielsen, A.2    Richelsen, B.3    Fredman, P.4    Buschard, K.5
  • 26
    • 36248951667 scopus 로고    scopus 로고
    • Iptakalim alleviates rotenone-induced degeneration of dopaminergic neurons through inhibiting microglia-mediated neuroinflammation
    • Zhou F, Wu JY, Sun XL, Yao HH, Ding JH, Hu G. Iptakalim alleviates rotenone-induced degeneration of dopaminergic neurons through inhibiting microglia-mediated neuroinflammation. Neuropsychopharmacology 2007 32 : 2570 2580.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 2570-2580
    • Zhou, F.1    Wu, J.Y.2    Sun, X.L.3    Yao, H.H.4    Ding, J.H.5    Hu, G.6
  • 27
    • 0021892605 scopus 로고
    • Properties of adenosine-triphosphate-regulated potassium channels in guinea-pig ventricular cells
    • Kakei M, Noma A, Shibasaki T. Properties of adenosine-triphosphate- regulated potassium channels in guinea-pig ventricular cells. J. Physiol. 1985 363 : 441 462. (Pubitemid 15000318)
    • (1985) Journal of Physiology , vol.VOL. 363 , pp. 441-462
    • Kakei, M.1    Noma, A.2    Shibasaki, T.3
  • 28
    • 38949207551 scopus 로고    scopus 로고
    • ATP channel-deficient pancreatic β-cells are streptozotocin resistant because of lower GLUT2 activity
    • ATP channel-deficient pancreatic β-cells are streptozotocin resistant because of lower GLUT2 activity. Am. J. Physiol. Endocrinol. Metab. 2008 294 : E326 35.
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.294 , pp. 326-35
    • Xu, J.1    Zhang, L.2    Chou, A.3
  • 31
    • 37349025060 scopus 로고    scopus 로고
    • The A3 adenosine receptor agonist CP-532,903 [n6-(2,5-dichlorobenzyl)- 3′-aminoadenosine-5′-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel
    • Wan TC, Ge ZD, Tampo A et al. The A3 adenosine receptor agonist CP-532,903 [N6-(2,5-dichlorobenzyl)-3′-aminoadenosine-5′-N- methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel. J. Pharmacol. Exp. Ther. 2008 324 : 234 243.
    • (2008) J. Pharmacol. Exp. Ther. , vol.324 , pp. 234-243
    • Wan, T.C.1    Ge, Z.D.2    Tampo, A.3
  • 32
    • 41649094871 scopus 로고    scopus 로고
    • Role of sulfonylurea receptor type 1 subunits of ATP-sensitive potassium channels in myocardial ischemia/reperfusion injury
    • Elrod JW, Harrell M, Flagg TP et al. Role of sulfonylurea receptor type 1 subunits of ATP-sensitive potassium channels in myocardial ischemia/reperfusion injury. Circulation 2008 117 : 1405 1413.
    • (2008) Circulation , vol.117 , pp. 1405-1413
    • Elrod, J.W.1    Harrell, M.2    Flagg, T.P.3
  • 37
    • 0036623636 scopus 로고    scopus 로고
    • Pre- and postsynaptic ATP-sensitive potassium channels during metabolic inhibition of rat hippocampal CA1 neurons
    • Matsumoto N, Komiyama S, Akaike N. Pre- and postsynaptic ATP-sensitive potassium channels during metabolic inhibition of rat hippocampal CA1 neurons. J. Physiol. 2002 541 : 511 520.
    • (2002) J. Physiol. , vol.541 , pp. 511-520
    • Matsumoto, N.1    Komiyama, S.2    Akaike, N.3
  • 38
    • 14644395509 scopus 로고    scopus 로고
    • Pore-forming subunits of K-ATP channels, Kir6.1 and Kir6.2, display prominent differences in regional and cellular distribution in the rat brain
    • Thomzig A, Laube G, Pruss H, Veh RW. Pore-forming subunits of K-ATP channels, Kir6.1 and Kir6.2, display prominent differences in regional and cellular distribution in the rat braJ. Comp. Neurol. 2005 484 : 313 330.
    • (2005) J. Comp. Neurol. , vol.484 , pp. 313-330
    • Thomzig, A.1    Laube, G.2    Pruss, H.3    Veh, R.W.4
  • 39
    • 0035684068 scopus 로고    scopus 로고
    • Kir6.1 is the principal pore-forming subunit of astrocyte but not neuronal plasma membrane K-ATP channels
    • Thomzig A, Wenzel M, Karschin C et al. Kir6.1 is the principal pore-forming subunit of astrocyte but not neuronal plasma membrane K-ATP channels. Mol. Cell. Neurosci. 2001 18 : 671 690.
    • (2001) Mol. Cell. Neurosci. , vol.18 , pp. 671-690
    • Thomzig, A.1    Wenzel, M.2    Karschin, C.3
  • 40
    • 54049142448 scopus 로고    scopus 로고
    • Opening of microglial K channels inhibits rotenone-induced neuroinflammation
    • Zhou F, Yao HH, Wu JY, Ding JH, Sun T, Hu G. Opening of microglial K channels inhibits rotenone-induced neuroinflammation. J. Cell. Mol. Med. 2008 12 : 1559 1570.
    • (2008) J. Cell. Mol. Med. , vol.12 , pp. 1559-1570
    • Zhou, F.1    Yao, H.H.2    Wu, J.Y.3    Ding, J.H.4    Sun, T.5    Hu, G.6
  • 41
    • 33748439683 scopus 로고    scopus 로고
    • Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects
    • Zunkler BJ. Human ether-a-go-go-related (HERG) gene and ATP-sensitive potassium channels as targets for adverse drug effects. Pharmacol. Ther. 2006 112 : 12 37.
    • (2006) Pharmacol. Ther. , vol.112 , pp. 12-37
    • Zunkler, B.J.1
  • 42
    • 0021086270 scopus 로고
    • + channels in cardiac muscle
    • + channels in cardiac muscle. Nature 1983 305 : 147 148.
    • (1983) Nature , vol.305 , pp. 147-148
    • Noma, A.1
  • 44
    • 33645824084 scopus 로고    scopus 로고
    • + channels in smooth muscle
    • + channels in smooth muscle. J. Physiol. 2006 572 : 617 624.
    • (2006) J. Physiol. , vol.572 , pp. 617-624
    • Teramoto, N.1
  • 46
    • 33846330196 scopus 로고    scopus 로고
    • Kir6.2-containing ATP-sensitive potassium channels protect cortical neurons from ischemic/anoxic injury in vitro and in vivo
    • Sun HS, Feng ZP, Barber PA, Buchan AM, French RJ. Kir6.2-containing ATP-sensitive potassium channels protect cortical neurons from ischemic/anoxic injury in vitro and in vivo. Neuroscience 2007 144 : 1509 1515.
    • (2007) Neuroscience , vol.144 , pp. 1509-1515
    • Sun, H.S.1    Feng, Z.P.2    Barber, P.A.3    Buchan, A.M.4    French, R.J.5
  • 50
    • 0036613906 scopus 로고    scopus 로고
    • ATP-sensitive K(+) channels in the brain: Sensors of hypoxic conditions
    • Yamada K, Inagaki N. ATP-sensitive K(+) channels in the brain: Sensors of hypoxic conditions. News Physiol. Sci. 2002 17 : 127 130.
    • (2002) News Physiol. Sci. , vol.17 , pp. 127-130
    • Yamada, K.1    Inagaki, N.2
  • 51
    • 0037341012 scopus 로고    scopus 로고
    • Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death
    • Tai KK, McCrossan ZA, Abbott GW. Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death. J. Neurochem. 2003 84 : 1193 1200.
    • (2003) J. Neurochem. , vol.84 , pp. 1193-1200
    • Tai, K.K.1    McCrossan, Z.A.2    Abbott, G.W.3
  • 52
    • 9644253068 scopus 로고    scopus 로고
    • Targeting mitochondrial ATP-sensitive potassium channels: A novel approach to neuroprotection
    • Busija DW, Lacza Z, Rajapakse N et al. Targeting mitochondrial ATP-sensitive potassium channels: A novel approach to neuroprotection. Brain Res. Brain Res. Rev. 2004 46 : 282 294.
    • (2004) Brain Res. Brain Res. Rev. , vol.46 , pp. 282-294
    • Busija, D.W.1    Lacza, Z.2    Rajapakse, N.3
  • 53
    • 0033389206 scopus 로고    scopus 로고
    • Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning
    • Gidday JM, Shah AR, Maceren RG et al. Nitric oxide mediates cerebral ischemic tolerance in a neonatal rat model of hypoxic preconditioning. J. Cereb. Blood Flow Metab. 1999 19 : 331 340.
    • (1999) J. Cereb. Blood Flow Metab. , vol.19 , pp. 331-340
    • Gidday, J.M.1    Shah, A.R.2    MacEren, R.G.3
  • 54
    • 7444244390 scopus 로고    scopus 로고
    • Glutamate efflux from human cerebrocortical slices during ischemia: Vesicular-like mode of glutamate release and sensitivity to A (2A) adenosine receptor blockade
    • Marcoli M, Bonfanti A, Roccatagliata P et al. Glutamate efflux from human cerebrocortical slices during ischemia: Vesicular-like mode of glutamate release and sensitivity to A (2A) adenosine receptor blockade. Neuropharmacology 2004 47 : 884 891.
    • (2004) Neuropharmacology , vol.47 , pp. 884-891
    • Marcoli, M.1    Bonfanti, A.2    Roccatagliata, P.3
  • 55
    • 19544365764 scopus 로고    scopus 로고
    • The AMPA-antagonist talampanel is neuroprotective in rodent models of focal cerebral ischemia
    • Erdo F, Berzsenyi P, Andrasi F. The AMPA-antagonist talampanel is neuroprotective in rodent models of focal cerebral ischemia. Brain Res. Bull. 2005 66 : 43 9.
    • (2005) Brain Res. Bull. , vol.66 , pp. 43-9
    • Erdo, F.1    Berzsenyi, P.2    Andrasi, F.3
  • 56
    • 6944226332 scopus 로고    scopus 로고
    • Targeting ischemic stroke with a novel opener of ATP-sensitive potassium channels in the brain
    • Wang H, Zhang YL, Tang XC, Feng HS, Hu G. Targeting ischemic stroke with a novel opener of ATP-sensitive potassium channels in the braMol. Pharmacol. 2004 66 : 1160 1168.
    • (2004) Mol. Pharmacol. , vol.66 , pp. 1160-1168
    • Wang, H.1    Zhang, Y.L.2    Tang, X.C.3    Feng, H.S.4    Hu, G.5
  • 57
    • 3242677157 scopus 로고    scopus 로고
    • Effects of iptakalim on rotenone-induced cytotoxicity and dopamine release from PC12 cells
    • Yang Y, Liu X, Ding JH et al. Effects of iptakalim on rotenone-induced cytotoxicity and dopamine release from PC12 cells. Neurosci. Lett. 2004 366 : 53 7.
    • (2004) Neurosci. Lett. , vol.366 , pp. 53-7
    • Yang, Y.1    Liu, X.2    Ding, J.H.3
  • 60
    • 0033841427 scopus 로고    scopus 로고
    • Do mitochondrial K(ATP) channels serve as triggers rather than end-effectors of ischemic preconditioning's protection?
    • Downey JM, Cohen MV. Do mitochondrial K(ATP) channels serve as triggers rather than end-effectors of ischemic preconditioning's protection? Basic Res. Cardiol. 2000 95 : 272 274.
    • (2000) Basic Res. Cardiol. , vol.95 , pp. 272-274
    • Downey, J.M.1    Cohen, M.V.2
  • 61
    • 0035823614 scopus 로고    scopus 로고
    • Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain
    • Bajgar R, Seetharaman S, Kowaltowski AJ, Garlid KD, Paucek P. Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in braJ. Biol. Chem. 2001 276 : 33 369 74.
    • (2001) J. Biol. Chem. , vol.276 , pp. 33369-74
    • Bajgar, R.1    Seetharaman, S.2    Kowaltowski, A.J.3    Garlid, K.D.4    Paucek, P.5
  • 63
    • 0036209260 scopus 로고    scopus 로고
    • Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release
    • Liu D, Lu C, Wan R, Auyeung WW, Mattson MP. Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release. J. Cereb. Blood Flow Metab. 2002 22 : 431 443.
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , pp. 431-443
    • Liu, D.1    Lu, C.2    Wan, R.3    Auyeung, W.W.4    Mattson, M.P.5
  • 65
    • 33846450277 scopus 로고    scopus 로고
    • The mitochondrial K (ATP) channel opener BMS-191095 reduces neuronal damage after transient focal cerebral ischemia in rats
    • Mayanagi K, Gaspar T, Katakam PV, Kis B, Busija DW. The mitochondrial K (ATP) channel opener BMS-191095 reduces neuronal damage after transient focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 2007 27 : 348 355.
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 348-355
    • Mayanagi, K.1    Gaspar, T.2    Katakam, P.V.3    Kis, B.4    Busija, D.W.5
  • 66
    • 33646813658 scopus 로고    scopus 로고
    • The neuroprotection conferred by activating the mitochondrial ATP-sensitive K(+) channel is mediated by inhibiting the mitochondrial permeability transition pore
    • Wu L, Shen F, Lin L, Zhang X, Bruce IC, Xia Q. The neuroprotection conferred by activating the mitochondrial ATP-sensitive K(+) channel is mediated by inhibiting the mitochondrial permeability transition pore. Neurosci. Lett. 2006 402 : 184 189.
    • (2006) Neurosci. Lett. , vol.402 , pp. 184-189
    • Wu, L.1    Shen, F.2    Lin, L.3    Zhang, X.4    Bruce, I.C.5    Xia, Q.6
  • 68
    • 33747615445 scopus 로고    scopus 로고
    • Blood-neural barrier: Intercellular communication at glio-vascular interface
    • Kim JH, Kim JH, Park JA et al. Blood-neural barrier: Intercellular communication at glio-vascular interface. J. Biochem. Mol. Biol. 2006 39 : 339 345.
    • (2006) J. Biochem. Mol. Biol. , vol.39 , pp. 339-345
    • Kim, J.H.1    Kim, J.H.2    Park, J.A.3
  • 69
    • 48249146963 scopus 로고    scopus 로고
    • Glial connexins and gap junctions in CNS inflammation and disease
    • Kielian T. Glial connexins and gap junctions in CNS inflammation and disease. J. Neurochem. 2008 106 : 1000 1016.
    • (2008) J. Neurochem. , vol.106 , pp. 1000-1016
    • Kielian, T.1
  • 70
    • 1642377170 scopus 로고    scopus 로고
    • Gap junctions and neurological disorders of the central nervous system
    • Nakase T, Naus CC. Gap junctions and neurological disorders of the central nervous system. Biochim. Biophys. Acta 2004 1662 : 149 158.
    • (2004) Biochim. Biophys. Acta , vol.1662 , pp. 149-158
    • Nakase, T.1    Naus, C.C.2
  • 71
    • 42149172269 scopus 로고    scopus 로고
    • Electrophysiological properties and gap junction coupling of striatal astrocytes
    • Adermark L, Lovinger DM. Electrophysiological properties and gap junction coupling of striatal astrocytes. Neurochem. Int. 2008 52 : 1365 1372.
    • (2008) Neurochem. Int. , vol.52 , pp. 1365-1372
    • Adermark, L.1    Lovinger, D.M.2
  • 72
    • 34247338931 scopus 로고    scopus 로고
    • Gap junctional control of glial glutamate transporter expression
    • Figiel M, Allritz C, Lehmann C, Engele J. Gap junctional control of glial glutamate transporter expression. Mol. Cell. Neurosci. 2007 35 : 130 137.
    • (2007) Mol. Cell. Neurosci. , vol.35 , pp. 130-137
    • Figiel, M.1    Allritz, C.2    Lehmann, C.3    Engele, J.4
  • 73
    • 15944387795 scopus 로고    scopus 로고
    • Emerging complexities in identity and function of glial connexins
    • Theis M, Sohl G, Eiberger J, Willecke K. Emerging complexities in identity and function of glial connexins. Trends Neurosci. 2005 28 : 188 195.
    • (2005) Trends Neurosci. , vol.28 , pp. 188-195
    • Theis, M.1    Sohl, G.2    Eiberger, J.3    Willecke, K.4
  • 74
    • 0141533205 scopus 로고    scopus 로고
    • New roles for astrocytes: Redefining the functional architecture of the brain
    • Nedergaard M, Ransom B, Goldman SA. New roles for astrocytes: Redefining the functional architecture of the braTrends Neurosci. 2003 26 : 523 530.
    • (2003) Trends Neurosci. , vol.26 , pp. 523-530
    • Nedergaard, M.1    Ransom, B.2    Goldman, S.A.3
  • 75
  • 79
    • 33644797572 scopus 로고    scopus 로고
    • Glutamate-mediated glial injury: Mechanisms and clinical importance
    • Matute C, Domercq M, Sanchez-Gomez MV. Glutamate-mediated glial injury: Mechanisms and clinical importance. Glia 2006 53 : 212 224.
    • (2006) Glia , vol.53 , pp. 212-224
    • Matute, C.1    Domercq, M.2    Sanchez-Gomez, M.V.3
  • 80
    • 33645899316 scopus 로고    scopus 로고
    • Role of astrocytes in glutamate homeostasis: Implications for excitotoxicity
    • Schousboe A, Waagepetersen HS. Role of astrocytes in glutamate homeostasis: Implications for excitotoxicity. Neurotox. Res. 2005 8 : 221 225.
    • (2005) Neurotox. Res. , vol.8 , pp. 221-225
    • Schousboe, A.1    Waagepetersen, H.S.2
  • 81
    • 0034069313 scopus 로고    scopus 로고
    • Glutamate uptake is decreased in platelets from Alzheimer's disease patients
    • Ferrarese C, Begni B, Canevari C et al. Glutamate uptake is decreased in platelets from Alzheimer's disease patients. Ann. Neurol. 2000 47 : 641 643.
    • (2000) Ann. Neurol. , vol.47 , pp. 641-643
    • Ferrarese, C.1    Begni, B.2    Canevari, C.3
  • 82
    • 0027527251 scopus 로고
    • Adenosine triphosphate depletion reverses sodium-dependent, neuronal uptake of glutamate in rat hippocampal slices
    • Madl JE, Burgesser K. Adenosine triphosphate depletion reverses sodium-dependent, neuronal uptake of glutamate in rat hippocampal slices. J. Neurosci. 1993 13 : 4429 4444.
    • (1993) J. Neurosci. , vol.13 , pp. 4429-4444
    • Madl, J.E.1    Burgesser, K.2
  • 83
    • 0036460164 scopus 로고    scopus 로고
    • Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia
    • Hamann M, Rossi DJ, Marie H, Attwell D. Knocking out the glial glutamate transporter GLT-1 reduces glutamate uptake but does not affect hippocampal glutamate dynamics in early simulated ischaemia. Eur. J. Neurosci. 2002 15 : 308 314.
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 308-314
    • Hamann, M.1    Rossi, D.J.2    Marie, H.3    Attwell, D.4
  • 84
    • 33745873475 scopus 로고    scopus 로고
    • Astrocyte control of synaptic transmission and neurovascular coupling
    • Haydon PG, Carmignoto G. Astrocyte control of synaptic transmission and neurovascular coupling. Physiol. Rev. 2006 86 : 1009 1031.
    • (2006) Physiol. Rev. , vol.86 , pp. 1009-1031
    • Haydon, P.G.1    Carmignoto, G.2
  • 85
    • 33645944970 scopus 로고    scopus 로고
    • Astrocyte activation in working brain: Energy supplied by minor substrates
    • Dienel GA, Cruz NF. Astrocyte activation in working brain: Energy supplied by minor substrates. Neurochem. Int. 2006 48 : 586 595.
    • (2006) Neurochem. Int. , vol.48 , pp. 586-595
    • Dienel, G.A.1    Cruz, N.F.2
  • 87
    • 0033779559 scopus 로고    scopus 로고
    • Astrocyte glutamate transport: Review of properties, regulation, and physiological functions
    • Anderson CM, Swanson RA. Astrocyte glutamate transport: Review of properties, regulation, and physiological functions. Glia 2000 32 : 1 14.
    • (2000) Glia , vol.32 , pp. 1-14
    • Anderson, C.M.1    Swanson, R.A.2
  • 88
    • 33646124971 scopus 로고    scopus 로고
    • Effects of systemic administration of iptakalim on extracellular neurotransmitter levels in the striatum of unilateral 6-hydroxydopamine-lesioned rats
    • Wang S, Hu LF, Zhang Y et al. Effects of systemic administration of iptakalim on extracellular neurotransmitter levels in the striatum of unilateral 6-hydroxydopamine-lesioned rats. Neuropsychopharmacology 2006 31 : 933 940.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 933-940
    • Wang, S.1    Hu, L.F.2    Zhang, Y.3
  • 89
    • 0037215645 scopus 로고    scopus 로고
    • Role of microglia in inflammation-mediated neurodegenerative diseases: Mechanisms and strategies for therapeutic intervention
    • Liu B, Hong JS. Role of microglia in inflammation-mediated neurodegenerative diseases: Mechanisms and strategies for therapeutic intervention. J. Pharmacol. Exp. Ther. 2003 304 : 1 7.
    • (2003) J. Pharmacol. Exp. Ther. , vol.304 , pp. 1-7
    • Liu, B.1    Hong, J.S.2
  • 90
    • 24144453087 scopus 로고    scopus 로고
    • Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism
    • Block ML, Hong JS. Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism. Prog. Neurobiol. 2005 76 : 77 98.
    • (2005) Prog. Neurobiol. , vol.76 , pp. 77-98
    • Block, M.L.1    Hong, J.S.2
  • 91
    • 20444466786 scopus 로고    scopus 로고
    • Role of inflammation in neurodegenerative diseases
    • Minghetti L. Role of inflammation in neurodegenerative diseases. Curr. OpNeurol. 2005 18 : 315 321.
    • (2005) Curr. OpNeurol. , vol.18 , pp. 315-321
    • Minghetti, L.1
  • 92
  • 93
    • 20344363680 scopus 로고    scopus 로고
    • Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats
    • Yang Y, Liu X, Long Y et al. Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats. J. Neurosci. Res. 2005 80 : 442 449.
    • (2005) J. Neurosci. Res. , vol.80 , pp. 442-449
    • Yang, Y.1    Liu, X.2    Long, Y.3
  • 94
    • 30344444268 scopus 로고    scopus 로고
    • Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats
    • Yang Y, Liu X, Long Y et al. Activation of mitochondrial ATP-sensitive potassium channels improves rotenone-related motor and neurochemical alterations in rats. Int. J. Neuropsychopharmacol. 2006 9 : 51 61.
    • (2006) Int. J. Neuropsychopharmacol. , vol.9 , pp. 51-61
    • Yang, Y.1    Liu, X.2    Long, Y.3
  • 95
    • 23844552880 scopus 로고    scopus 로고
    • Post-ischemic administration of diazoxide attenuates long-term microglial activation in the rat brain after permanent carotid artery occlusion
    • Farkas E, Timmer NM, Domoki F, Mihaly A, Luiten PG, Bari F. Post-ischemic administration of diazoxide attenuates long-term microglial activation in the rat brain after permanent carotid artery occlusion. Neurosci. Lett. 2005 387 : 168 172.
    • (2005) Neurosci. Lett. , vol.387 , pp. 168-172
    • Farkas, E.1    Timmer, N.M.2    Domoki, F.3    Mihaly, A.4    Luiten, P.G.5    Bari, F.6
  • 96
    • 1942519268 scopus 로고    scopus 로고
    • Adult brain neurogenesis and pathology
    • Rougier A, Auvergne R. Adult brain neurogenesis and pathology. Neurochirurgie 2004 50 : 33 41.
    • (2004) Neurochirurgie , vol.50 , pp. 33-41
    • Rougier, A.1    Auvergne, R.2
  • 97
    • 33645886343 scopus 로고    scopus 로고
    • Discovery of neurogenic, Alzheimer's disease therapeutics
    • Kelleher-Andersson J. Discovery of neurogenic, Alzheimer's disease therapeutics. Curr. Alzheimer Res. 2006 3 : 55 62.
    • (2006) Curr. Alzheimer Res. , vol.3 , pp. 55-62
    • Kelleher-Andersson, J.1
  • 98
    • 24344506586 scopus 로고    scopus 로고
    • Hypoxic-ischemic injury stimulates subventricular zone proliferation and neurogenesis in the neonatal rat
    • Ong J, Plane JM, Parent JM, Silverstein FS. Hypoxic-ischemic injury stimulates subventricular zone proliferation and neurogenesis in the neonatal rat. Pediatr. Res. 2005 58 : 600 606.
    • (2005) Pediatr. Res. , vol.58 , pp. 600-606
    • Ong, J.1    Plane, J.M.2    Parent, J.M.3    Silverstein, F.S.4
  • 99
    • 0034713931 scopus 로고    scopus 로고
    • ATP channels regulate mitogenically induced proliferation in primary rat hepatocytes and human liver cell lines. Implications for liver growth control and potential therapeutic targeting
    • ATP channels regulate mitogenically induced proliferation in primary rat hepatocytes and human liver cell lines. Implications for liver growth control and potential therapeutic targeting. J. Biol. Chem. 2000 275 : 26 050 7.
    • (2000) J. Biol. Chem. , vol.275 , pp. 26050-7
    • Malhi, H.1    Irani, A.N.2    Rajvanshi, P.3
  • 101
    • 15744397784 scopus 로고    scopus 로고
    • ATP channel opener, in cultured rabbit pulmonary arterial smooth muscle cells
    • ATP channel opener, in cultured rabbit pulmonary arterial smooth muscle cells. Eur. J. Pharmacol. 2005 511 : 81 7.
    • (2005) Eur. J. Pharmacol. , vol.511 , pp. 81-7
    • Xie, W.1    Wang, H.2    Ding, J.3    Wang, H.4    Hu, G.5
  • 102
    • 0028274806 scopus 로고
    • Altered control of vascular tone by adenosine triphosphate-sensitive potassium channels in rats with cirrhosis
    • Moreau R, Komeichi H, Kirstetter P, Ohsuga M, Cailmail S, Lebrec D. Altered control of vascular tone by adenosine triphosphate-sensitive potassium channels in rats with cirrhosis. Gastroenterology 1994 106 : 1016 1023.
    • (1994) Gastroenterology , vol.106 , pp. 1016-1023
    • Moreau, R.1    Komeichi, H.2    Kirstetter, P.3    Ohsuga, M.4    Cailmail, S.5    Lebrec, D.6
  • 103
    • 0036775363 scopus 로고    scopus 로고
    • The molecular site of action of K(ATP) channel inhibitors determines their ability to inhibit iNOS-mediated relaxation in rat aorta
    • Wilson AJ, Clapp LH. The molecular site of action of K(ATP) channel inhibitors determines their ability to inhibit iNOS-mediated relaxation in rat aorta. Cardiovasc. Res. 2002 56 : 154 163.
    • (2002) Cardiovasc. Res. , vol.56 , pp. 154-163
    • Wilson, A.J.1    Clapp, L.H.2
  • 104
    • 0028222484 scopus 로고
    • Maturation enhances the sensitivity of ovine cerebral arteries to the ATP-sensitive potassium channel activator lemakalim
    • Pearce WJ, Elliott SR. Maturation enhances the sensitivity of ovine cerebral arteries to the ATP-sensitive potassium channel activator lemakalim. Pediatr. Res. 1994 35 : 729 732.
    • (1994) Pediatr. Res. , vol.35 , pp. 729-732
    • Pearce, W.J.1    Elliott, S.R.2
  • 105
    • 0033041929 scopus 로고    scopus 로고
    • Attenuation of basilar artery spasm after experimental subarachnoid hemorrhage in rabbit by potassium channel activator cromakalim: A preliminary result
    • (in Chinese)
    • Kwan AL, Lin CL, Howng SL. Attenuation of basilar artery spasm after experimental subarachnoid hemorrhage in rabbit by potassium channel activator cromakalim: A preliminary result. Kaohsiung J. Med. Sci. 1999 15 : 268 273 (in Chinese).
    • (1999) Kaohsiung J. Med. Sci. , vol.15 , pp. 268-273
    • Kwan, A.L.1    Lin, C.L.2    Howng, S.L.3
  • 106
    • 0030053872 scopus 로고    scopus 로고
    • + channels in the vertebrobasilar system of the rabbit
    • + channels in the vertebrobasilar system of the rabbit. Circ. Res. 1996 78 : 238 243.
    • (1996) Circ. Res. , vol.78 , pp. 238-243
    • Nagao, T.1    Ibayashi, S.2    Sadoshima, S.3
  • 107
    • 0030663434 scopus 로고    scopus 로고
    • + channel function in piglet cerebral arteries
    • + channel function in piglet cerebral arteries. Stroke 1997 28 : 2273 2279.
    • (1997) Stroke , vol.28 , pp. 2273-2279
    • Armstead, W.M.1
  • 108
  • 109
    • 0038076108 scopus 로고    scopus 로고
    • ATP-sensitive potassium channels mediate dilatation of basilar artery in response to intracellular acidification in vivo
    • Santa N, Kitazono T, Ago T et al. ATP-sensitive potassium channels mediate dilatation of basilar artery in response to intracellular acidification in vivo. Stroke 2003 34 : 1276 1280.
    • (2003) Stroke , vol.34 , pp. 1276-1280
    • Santa, N.1    Kitazono, T.2    Ago, T.3
  • 110
    • 0026447220 scopus 로고
    • + ATP-channel activation causes marked vasodilation in the hypertensive neonatal pig lung
    • + ATP-channel activation causes marked vasodilation in the hypertensive neonatal pig lung. Am. J. Physiol. 1992 263 : H1532 6.
    • (1992) Am. J. Physiol. , vol.263 , pp. 1532-6
    • Pinheiro, J.M.1    Malik, A.B.2
  • 111
    • 33751304218 scopus 로고    scopus 로고
    • Role of ATP-sensitive potassium channels in brain stem circulation during hypotension
    • Toyoda K, Fujii K, Ibayashi S, Kitazono T, Nagao T, Fujishima M. Role of ATP-sensitive potassium channels in brain stem circulation during hypotension. Am. J. Physiol. 1997 273 : H1342 6.
    • (1997) Am. J. Physiol. , vol.273 , pp. 1342-6
    • Toyoda, K.1    Fujii, K.2    Ibayashi, S.3    Kitazono, T.4    Nagao, T.5    Fujishima, M.6
  • 114
    • 33947305301 scopus 로고    scopus 로고
    • Bradykinin-induced blood-brain tumor barrier permeability increase is mediated by adenosine 5′-triphosphate-sensitive potassium channel
    • DOI 10.1016/j.brainres.2007.01.133, PII S000689930700193X
    • Zhang H, Gu YT, Xue YX. Bradykinin-induced blood-brain tumor barrier permeability increase is mediated by adenosine 5′-triphosphate-sensitive potassium channel. Brain Res. 2007 1144 : 33 41. (Pubitemid 46440831)
    • (2007) Brain Research , vol.1144 , Issue.1 , pp. 33-41
    • Zhang, H.1    Ting Gu, Y.2    Xue, Y.X.3
  • 115
    • 22144432288 scopus 로고    scopus 로고
    • Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability
    • Lenzser G, Kis B, Bari F, Busija DW. Diazoxide preconditioning attenuates global cerebral ischemia-induced blood-brain barrier permeability. Brain Res. 2005 1051 : 72 80.
    • (2005) Brain Res. , vol.1051 , pp. 72-80
    • Lenzser, G.1    Kis, B.2    Bari, F.3    Busija, D.W.4
  • 116
    • 58149192688 scopus 로고    scopus 로고
    • Delivery of peptides to the brain: Emphasis on therapeutic development
    • Banks WA. Delivery of peptides to the brain: Emphasis on therapeutic development. Biopolymers 2008 90 : 589 594.
    • (2008) Biopolymers , vol.90 , pp. 589-594
    • Banks, W.A.1
  • 117
    • 33747368249 scopus 로고    scopus 로고
    • Blood-brain barrier: Structural components and function under physiologic and pathologic conditions
    • Persidsky Y, Ramirez SH, Haorah J, Kanmogne GD. Blood-brain barrier: Structural components and function under physiologic and pathologic conditions. J. Neuroimmune Pharmacol. 2006 1 : 223 236.
    • (2006) J. Neuroimmune Pharmacol. , vol.1 , pp. 223-236
    • Persidsky, Y.1    Ramirez, S.H.2    Haorah, J.3    Kanmogne, G.D.4
  • 119
    • 0035201474 scopus 로고    scopus 로고
    • Attenuation of ischemic brain edema and cerebrovascular injury after ischemic preconditioning in the rat
    • Masada T, Hua Y, Xi G, Ennis SR, Keep RF. Attenuation of ischemic brain edema and cerebrovascular injury after ischemic preconditioning in the rat. J. Cereb. Blood Flow Metab. 2001 21 : 22 33.
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , pp. 22-33
    • Masada, T.1    Hua, Y.2    Xi, G.3    Ennis, S.R.4    Keep, R.F.5


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