Systematic administration of iptakalim, an ATP-sensitive potassium channel opener, prevents rotenone-induced motor and neurochemical alterations in rats

Journal of Neuroscience Research

Volumn 80, Issue 3, 2005, Pages 442-449

  Yang, Yong ^a   Liu, Xing ^a   Long, Yan ^a   Wang, Fang ^a   Ding, Jian Hua ^a   Liu, Su Yi ^a   Sun, Ye Hong ^a   Yao, Hong Hong ^a   Wang, Hai ^b   Wu, Jie ^a,c   Hu, Gang ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY   (China)

^c BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

Diazoxide; Inducible nitric oxide synthase; Iptakalim; Mitochondrial ATP sensitive potassium channels; Parkinson's disease

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE; DIAZOXIDE; DOPAMINE; INDUCIBLE NITRIC OXIDE SYNTHASE; IPTAKALIM; MESSENGER RNA; POTASSIUM CHANNEL; POTASSIUM CHANNEL AFFECTING AGENT; POTASSIUM CHANNEL BLOCKING AGENT; ROTENONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BRAIN ISCHEMIA; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; CORPUS STRIATUM; DEGENERATIVE DISEASE; DRUG EFFECT; ENZYME ACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOCHONDRION; MOTOR PERFORMANCE; NEUROCHEMISTRY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PARKINSON DISEASE; PARKINSONISM; PRIORITY JOURNAL; RAT; STRIATONIGRAL DEGENERATION; SUBSTANTIA NIGRA; SYMPTOMATOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BASAL GANGLIA; BRAIN; BRAIN CHEMISTRY; CATALEPSY; DIAZOXIDE; DISEASE MODELS, ANIMAL; DOPAMINE; DOWN-REGULATION; DRUG ADMINISTRATION SCHEDULE; MALE; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; PARKINSONIAN DISORDERS; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROPYLAMINES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; ROTENONE; UNCOUPLING AGENTS;

EID: 20344363680     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20467     Document Type: Article

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