Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death

Journal of Neurochemistry

Volumn 84, Issue 5, 2003, Pages 1193-1200

  Tai, Kwok Keung ^a,b   McCrossan, Zoe A ^c   Abbott, Geoffrey W ^c  

^a LONG BEACH MEMORIAL MEDICAL CENTER   (United States)

^b Parkinson's and Movement Disorder Institute   (United States)

^c NONE

Author keywords

Channels; KATP; Neuroprotection; Parkinson's disease; Preconditioning; Rotenone

Indexed keywords

2 CYANO 1 (1,1 DIMETHYLPROPYL) 3 (3 PYRIDYL)GUANIDINE; 5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE; CLAMIKALANT; DIAZOXIDE; GLIBENCLAMIDE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM ION; ROTENONE; TRYPAN BLUE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL MEMBRANE; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; IMMUNOREACTIVITY; NEUROTOXICITY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BLOTTING, WESTERN; CELL DEATH; CELL MEMBRANE; CELL SURVIVAL; DIAZOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; MITOCHONDRIA; PATCH-CLAMP TECHNIQUES; PC12 CELLS; PHEOCHROMOCYTOMA; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RECEPTORS, DRUG; ROTENONE; SUBCELLULAR FRACTIONS; UNCOUPLING AGENTS;

ANIMALIA;

EID: 0037341012     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01625.x     Document Type: Article

References (28)

1. Ashcroft S. J. and Ashcroft F. M. (1990) Properties and functions of ATP-sensitive K-channels. Cell Signal. 2, 197-214.
2. Bajgar R., Seetharaman S., Kowallowski A. J., Garlid K. D. and Paucek P. (2001) Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain. J. Biol. Chem. 276, 33369-33374.
3. Betarbet R., Sherer T. B., MacKenzie G., Garcia-Osuna M., Panov A. V. and Greenamyre J. T. (2000) Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 3, 1301-1306.
4. Clement J. P., IV, Kunjilwar K., Gonzalez G., Schwanstecher M., Panten U., Aguilar-Bryan L. and Bryan J. (1997) Association and stoichiometry of K (ATP) channel subunits. Neuron 18, 827-838.
5. De Weille J. R., Fosset M., Schmid-Antomarchi H. and Lazdunski M. (1989) Galanin inhibits dopamine secretion and activates a potassium channel in pheochromocytoma cells. Brain Res. 485, 199-203.
6. Garlid K. D., Paucek P, Yarov-Yarovoy V., Murray H. N., Darbenzio R. B., D'Alonzo A. J., Lodge N. J., Smith M. A. and Grover G. J. (1997) Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels. Possible mechanism of cardioprotection. Circ. Res. 81, 1072-1082.
7. Grover G. J. (1997) Pharmacology of ATP-sensitive potassium channel (KATP) openers in models of myocardial ischemic and reperfusion. Can. J. Physiol. Phamacol. 75, 309-315.
8. Grover G. J., Sleph P. G. and Dzwonczyk S. (1992) Role of myocardial ATP-sensitive potassium channels in mediating preconditioning in the dog heart and their possible interaction with adenosine Al-receptors. Circulation 86, 1310-1316.
9. Grover G. J., D'Alonzo A. J., Parham C. S. and Darbenzio R. B. (1995) Cardioprotection with the KATP opener cromakalim is not correlated with ischemic myocardial action potential duration. J. Cardiovasc. Pharmacol. 26, 145-152.
10. + channels in cerebral ischemic preconditioning. Proc. Natl Acad. Sci. USA 92, 4666-4670.
11. Holmuhamedov E. L., Jovanovic S., Dzeja P. P., Jovanovic A. and Terzic A. (1998) Mitochondrial ATP-sensitive K+ channels modulate cardiac mitochondrial function. Am. J. Physiol. 275, H1567-H1576.
12. Hu H., Sato T., Seharaseyon J., Liu Y., Johns D. C., O'Rourke B. and Marban E. (1999) Pharmacological and histochemical distinctions between molecularly defined sarcolemmal KATP channels and native cardiac mitochondrial KATP channels. Mol Pharmacol. 55, 1000-1005.
13. Jilkina O., Kuzio B., Grover G. J. and Kupriyanov V. V. (2002) Effects of K (ATP) channel openers, P-1075, pinacidil, and diazoxide, on energetics and contractile function in isolated rat hearts. J. Mol. Cell. Cardiol. 34, 427-440.
14. Kitagawa K., Matsumoto M., Tagaya M., Hata R., Ueda H., Niinobe M., Handa N., Fukunaga R., Kimura K., Mikoshiba K. and Kamada T. (1990) 'Ischemic tolerance' phenomenon found in the brain. Brain Res. 528, 21-24.
15. Lamensdorf I., He L., Nechushtan A., Harvey-White J., Eisenhofer G., Milan R., Rojas E. and Kopin I. J. (2000) Effect of glipizide on dopamine synthesis, release and metabolism in PC12 cells. Eur J. Pharmacol. 388, 147-154.
16. Liu Y., Ren G., O'Rourke B., Marban E. and Seharaseyon J. (2001) Pharmacological comparison of native mitochondrial K (ATP) channels with molecularly defined surface K (ATP) channels. Mol. Pharmacol. 59, 225-230.
17. Liu D., Lu C., Wan R., Auyeung W. W. and Mattson M. P. (2002) Activation of mitohondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release. J. Cereb. Blood Flow Metab. 22, 431-443.
18. Mattson M. P., Duan W., Pedersen W. A. and Culmsee C. (2001) Neurodegenerative disorders and ischemic brain diseases. Apoptosis 6, 69-81.
19. Melamed-Frank M., Terzic A., Carrasco A. J., Nevo E., Avivi A. and Levy A. P. (2001) Reciprocal regulation of expression of pore-forming KATP channel genes by hypoxia. Mol. Cell. Biochem. 225, 145-150.
20. Murry C. E., Jennings R. B. and Reimer K. A. (1986) Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74, 1124-1136.
21. Nantel A., Huber M. and Thomas D. Y. (1999) Localization, of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 pool. J. Biol. Chem. 274, 35719-35724.
22. ATP channels in rat dopaminergic substantia nigra neurones. Pflugers Arch. 430, 44-54.
23. Sato T, Sasaki N., Seharaseyon J., O'Rourke B. and Marban E. (2000) Selective pharmacological agents implicate mitochondrial but not sarcolemmal K (ATP) channels in ischemic cardioprotection. Cirulation 101, 2418-2423.
24. Suzuki M., Kotake K., Fujikura K., Inagaki N., Suzuki T., Gonoi T., Seino S. and Takata K. (1997) Kir6.1: a possible subunit of ATP-sensitive K+ channels in mitochondria. Biochem. Biophys. Res. Commun. 241, 693-697.
25. Szewczyk A., Wojcik G., Lobanov N. A. and Nalecz M. J. (1997) The mitochondrial sulfonylurea receptor: identification and characterization. Biochem. Biophys. Res. Commun. 230, 611-615.
26. Tai K. K. and Truong D. D. (2002) Activation of ATP-sensitive potassium channel confers protection against rotenone-induced cell death: therapeutic implications for Parkinson's disease. J. Neurosci. Res. 69, 559-566.
27. 3H]U69593 binding sites in the rat heart by receptor binding assays. J. Mol. Cell. Cardiol. 23, 1297-1302.
28. Tai K. K., Blondelle S. E., Ostresh J. M., Houghten R. A. and Montal M. (2001) An N-methyl-D-aspartate receptor channel blocker with neuroprotective activity. Proc. Natl Acad. Sci. USA 98, 3519-3524.