메뉴 건너뛰기




Volumn 511, Issue 2-3, 2005, Pages 81-87

Anti-proliferating effect of iptakalim, a novel KATP channel opener, in cultured rabbit pulmonary arterial smooth muscle cells

Author keywords

ATP sensitive potassium channel; Fluo 3; Iptakalim; Proliferation; Pulmonary arterial smooth muscle cell

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; ENDOTHELIN 1; GLIBENCLAMIDE; IPTAKALIM; POTASSIUM CHANNEL STIMULATING AGENT; THYMIDINE; TRITIUM; UNCLASSIFIED DRUG;

EID: 15744397784     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.01.039     Document Type: Article
Times cited : (26)

References (24)
  • 2
    • 0027397544 scopus 로고
    • Inositol triphosphate and calcium signaling
    • M.J. Berridge Inositol triphosphate and calcium signaling Nature 361 1993 315 325
    • (1993) Nature , vol.361 , pp. 315-325
    • Berridge, M.J.1
  • 3
    • 0034116766 scopus 로고    scopus 로고
    • Electrophysiological effects of endothelin-1 and their relationship to contraction in rat renal arterial smooth muscle
    • L.C. Betts, and R.Z. Kozlowski Electrophysiological effects of endothelin-1 and their relationship to contraction in rat renal arterial smooth muscle Br. J. Pharmacol. 130 4 2000 787 796
    • (2000) Br. J. Pharmacol. , vol.130 , Issue.4 , pp. 787-796
    • Betts, L.C.1    Kozlowski, R.Z.2
  • 5
    • 0037284180 scopus 로고    scopus 로고
    • ATP-sensitive K+ channels of vascular smooth muscle cells
    • W.C. Cole, and O. Clement-Chomienne ATP-sensitive K+ channels of vascular smooth muscle cells J. Cardiovasc. Electrophysiol. 14 1 2003 94 103
    • (2003) J. Cardiovasc. Electrophysiol. , vol.14 , Issue.1 , pp. 94-103
    • Cole, W.C.1    Clement-Chomienne, O.2
  • 6
    • 0029827405 scopus 로고    scopus 로고
    • + current that is active at resting potential in rabbit pulmonary artery smooth muscle cells
    • + current that is active at resting potential in rabbit pulmonary artery smooth muscle cells J. Physiol. (Lond.) 496 1996 407 420
    • (1996) J. Physiol. (Lond.) , vol.496 , pp. 407-420
    • Evans, A.M.1    Osipenko, O.N.2    Gurney, A.M.3
  • 7
    • 0028032853 scopus 로고
    • Voltage window for sustained elevation of cytosolic calcium in smooth muscle cells
    • B.K. Fleischmann, R.K. Murray, and M.I. Kotlikoff Voltage window for sustained elevation of cytosolic calcium in smooth muscle cells Proc. Natl. Acad. Sci. U. S. A. 91 1994 11914 11918
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 11914-11918
    • Fleischmann, B.K.1    Murray, R.K.2    Kotlikoff, M.I.3
  • 9
    • 0031019855 scopus 로고    scopus 로고
    • Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression
    • G.E. Hardingham, S. Chawala, C.M. Johnson, and H. Bading Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression Nature 385 1997 260 265
    • (1997) Nature , vol.385 , pp. 260-265
    • Hardingham, G.E.1    Chawala, S.2    Johnson, C.M.3    Bading, H.4
  • 10
    • 0032819101 scopus 로고    scopus 로고
    • Enhanced et (A)-receptor-mediated inhibition of K (v) channels in hypoxic hypertensive rat pulmonary artery myocytes
    • K.X. Li, B. Fouty, I.F. McMurtry, and D.M. Rodman Enhanced ET (A)-receptor-mediated inhibition of K (v) channels in hypoxic hypertensive rat pulmonary artery myocytes Am. J. Physiol. 277 1999 H363 H370
    • (1999) Am. J. Physiol. , vol.277
    • Li, K.X.1    Fouty, B.2    McMurtry, I.F.3    Rodman, D.M.4
  • 12
    • 0028232968 scopus 로고
    • Calcium calmodulin and cell cycle regulation
    • A.R. Means Calcium calmodulin and cell cycle regulation FEBS Lett. 347 1994 1 4
    • (1994) FEBS Lett. , vol.347 , pp. 1-4
    • Means, A.R.1
  • 13
    • 0034815008 scopus 로고    scopus 로고
    • The pathobiology of pulmonary hypertension: Smooth muscle cells and ion channels
    • S. Rich V.V. Mclaughlin Saunders Philadelphia
    • E.D. Michelakis, and E.K. Weir The pathobiology of pulmonary hypertension: smooth muscle cells and ion channels S. Rich V.V. Mclaughlin Clinics in chest medicine: pulmonary hypertension 22 (3) 2001 Saunders Philadelphia 419 432
    • (2001) Clinics in Chest Medicine: Pulmonary Hypertension , vol.223 , pp. 419-432
    • Michelakis, E.D.1    Weir, E.K.2
  • 14
    • 0029108913 scopus 로고
    • Physiological roles and properties of potassium channels in arterial smooth muscle
    • M.T. Nelson, and J.M. Quayle Physiological roles and properties of potassium channels in arterial smooth muscle Am. J. Physiol. 268 1995 C799 C822
    • (1995) Am. J. Physiol. , vol.268
    • Nelson, M.T.1    Quayle, J.M.2
  • 15
    • 0025298548 scopus 로고
    • Calcium channels, potassium channels and voltage dependence of arterial smooth muscle tone
    • M.T. Nelson, J.B. Patlak, J.F. Worley, and N.B. Standen Calcium channels, potassium channels and voltage dependence of arterial smooth muscle tone Am. J. Physiol. 259 1990 C3 C18
    • (1990) Am. J. Physiol. , vol.259
    • Nelson, M.T.1    Patlak, J.B.2    Worley, J.F.3    Standen, N.B.4
  • 18
    • 0030772859 scopus 로고    scopus 로고
    • ATP-sensitive and inwardly rectifying potassium channel in smooth muscle
    • J.M. Quayle, M.T. Nelson, and N.B. Standen ATP-sensitive and inwardly rectifying potassium channel in smooth muscle Physiol. Rev. 77 1997 1165 1232
    • (1997) Physiol. Rev. , vol.77 , pp. 1165-1232
    • Quayle, J.M.1    Nelson, M.T.2    Standen, N.B.3
  • 19
    • 0037326313 scopus 로고    scopus 로고
    • Differential effects of sulphonylureas on the vasodilatory response evoked by K(ATP) channel openers
    • D. Ravel, N. Levens, M. Feletou, G. Neliat, J. Auclair, and E. Bouskela Differential effects of sulphonylureas on the vasodilatory response evoked by K(ATP) channel openers Fundam. Clin. Pharmacol. 17 2003 61 69
    • (2003) Fundam. Clin. Pharmacol. , vol.17 , pp. 61-69
    • Ravel, D.1    Levens, N.2    Feletou, M.3    Neliat, G.4    Auclair, J.5    Bouskela, E.6
  • 20
    • 0015097243 scopus 로고
    • The smooth muscle cell II. Growth of smooth muscle in culture and formation of elastic fibers
    • R. Ross The smooth muscle cell II. Growth of smooth muscle in culture and formation of elastic fibers J. Cell Biol. 50 1971 172 186
    • (1971) J. Cell Biol. , vol.50 , pp. 172-186
    • Ross, R.1
  • 21
    • 0034065943 scopus 로고    scopus 로고
    • Mechanism of hypoxic pulmonary vasoconstriction involves et (A) receptor-mediated inhibition of K (ATP) channel
    • K. Sato, Y. Morio, K.G. Morris, D.M. Rodman, and I.F. McMurtry Mechanism of hypoxic pulmonary vasoconstriction involves ET (A) receptor-mediated inhibition of K (ATP) channel Am. J. Physiol. 278 2000 L434 L442
    • (2000) Am. J. Physiol. , vol.278
    • Sato, K.1    Morio, Y.2    Morris, K.G.3    Rodman, D.M.4    McMurtry, I.F.5
  • 22
    • 0037282533 scopus 로고    scopus 로고
    • Pharmacological characteristics of the novel antihypertensive drug iptakalim hydrochloride and its molecular mechanisms
    • H. Wang Pharmacological characteristics of the novel antihypertensive drug iptakalim hydrochloride and its molecular mechanisms Drug Dev. Res. 58 2003 65 68
    • (2003) Drug Dev. Res. , vol.58 , pp. 65-68
    • Wang, H.1
  • 23
    • 4243059647 scopus 로고    scopus 로고
    • Effects of iptakalim hydrochloride, a novel KATP channel opener, on pulmonary vascular remodeling in hypoxic rats
    • W. Xie, H. Wang, H. Wang, and G. Hu Effects of iptakalim hydrochloride, a novel KATP channel opener, on pulmonary vascular remodeling in hypoxic rats Life Sci. 75 2004 2065 2076
    • (2004) Life Sci. , vol.75 , pp. 2065-2076
    • Xie, W.1    Wang, H.2    Wang, H.3    Hu, G.4
  • 24
    • 0029145956 scopus 로고
    • 2+]i in pulmonary artery myocytes
    • 2+]i in pulmonary artery myocytes Circ. Res. 77 1995 370 378
    • (1995) Circ. Res. , vol.77 , pp. 370-378
    • Yuan, X.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.