Do mitochondrial K(ATP) channels serve as triggers rather than end-effectors of ischemic preconditioning's protection?

Basic Research in Cardiology

Volumn 95, Issue 4, 2000, Pages 272-274

  Downey, J M ^a   Cohen, M V ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYDECANOIC ACID; ACETYLCHOLINE; ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; CALCIUM; CHELERYTHRINE; DIAZOXIDE; FREE RADICAL; G PROTEIN COUPLED RECEPTOR; GENISTEIN; GLIBENCLAMIDE; MITOGEN ACTIVATED PROTEIN KINASE; MYXOTHIAZOL; OPIATE AGONIST; POTASSIUM; POTASSIUM CHANNEL; PROTEIN KINASE; PROTEIN KINASE C; TIOPRONIN;

CALCIUM TRANSPORT; CHANNEL GATING; HEART; HEART INFARCTION PREVENTION; HEART MITOCHONDRION; HEART MUSCLE ISCHEMIA; NONHUMAN; REVIEW;

ADENOSINE TRIPHOSPHATE; ANIMALS; DECANOIC ACIDS; HUMANS; HYDROXY ACIDS; ISCHEMIC PRECONDITIONING; MITOCHONDRIA, HEART; POTASSIUM CHANNELS;

EID: 0033841427     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003950070045     Document Type: Review

References (19)

1. Potassium channels and preconditioning of isolated rabbit cardiomyocytes: effects of glyburide and pinacidil
2. Signal transduction in ischemic preconditioning: The role of kinases and mitochondrial K(ATP) channels
3. Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardium
4. Ischemic preconditioning depends on interaction between mitochondrial K(ATP) channels and actin cytoskeleton
5. The protective effect of diozoxide is blocked by antioxidants
6. Opioid-induced second window of cardioprotection: Potential role of mitochondrial K(ATP) channels
7. Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels: Possible mechanism of cardioprotection
8. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs
9. Preconditioning is not abolished by the delayed rectifier K+ blocker dofetilide
10. Cardioprotection with the K(ATP) opener cromakalim is not correlated with ischemic myocardial action potential duration
11. Mitochondrial ATP-dependent potassium channels: Novel effectors of cardioprotection?
12. Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
13. Opening of mithocondrial K(ATP) channel induces early and delayed cardioprotective effect: Role of nitric oxide
14. The mitochondrial K(ATP) channel may be a trigger rather than the end-effector of preconditioning's anti-infarct effect
15. Oxygen radicals can induce preconditioning in rabbit hearts
16. Activation of mitochondrial ATP-sensitive K+ channel for cardiac protection against ischemic injury is dependent on protein kinase C activity
17. Diazoxide protects the heart be release of free radicals
18. Effects of the K(ATP) channel opener bimakalim on coronary blood flow, monophasic action potential duration and infarct size in dogs
19. Role of reactive oxygen species in acetylcholine-induced preconditioning in cardiomyocytes