Potency values from the local lymph node assay: Application to classification, labelling and risk assessment

Regulatory Toxicology and Pharmacology

Volumn 56, Issue 1, 2010, Pages 54-66

  Loveless, S E ^a   Api, A M ^b   Crevel, R W R ^c   Debruyne, E ^d   Gamer, A ^e   Jowsey, I R ^c   Kern, P ^f   Kimber, I ^g   Lea, L ^h   Lloyd, P ⁱ   Mehmood, Z ^j   Steiling, W ^k   Veenstra, G ^l   Woolhiser, M ^m   Hennes, C ⁿ  

^a DUPONT COMPANY   (United States)

^b RESEARCH INSTITUTE FOR FRAGRANCE MATERIALS   (United States)

^c UNILEVER RESEARCH   (United Kingdom)

^d BAYER AG   (Germany)

^e BASF SE   (Germany)

^f NV Procter Gamble Eurocor SA   (Belgium)

^g UNIVERSITY OF MANCHESTER   (United Kingdom)

^h Givaudan SA   (Switzerland)

ⁱ S C Johnson & Son Inc   (United States)

^j Huntsman Europe   (Belgium)

^k HENKEL KGAA   (Germany)

^l SHELL GLOBAL SOLUTIONS INTERNATIONAL B V   (United States)

^m DOW CHEMICAL COMPANY   (United States)

ⁿ European Centre for Ecotoxicology and Toxicology of Chemicals   (Belgium)

more..

Author keywords

Classification; Labelling; Local lymph node assay (LLNA); Potency; Risk assessment; Skin sensitisation

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ANILINE; CONTACT ALLERGEN; DIMETHYL SULFOXIDE; LIMONENE; METHACRYLIC ACID METHYL ESTER; PYRIDINE;

ACCURACY; ARTICLE; CLASSIFICATION; CONCENTRATION RESPONSE; HEALTH HAZARD; HUMAN; LOCAL LYMPH NODE ASSAY; LYMPHOCYTE PROLIFERATION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REFERENCE VALUE; RISK ASSESSMENT; RISK MANAGEMENT; SKIN ALLERGY; SKIN SENSITIZATION;

ALLERGENS; ANIMALS; BIOLOGICAL ASSAY; DERMATITIS, ALLERGIC CONTACT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG LABELING; HUMANS; LOCAL LYMPH NODE ASSAY; PRODUCT LABELING; RISK ASSESSMENT; SKIN TESTS;

EID: 75549092177     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2009.08.016     Document Type: Article

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