Measurement of allergenic potency using the local lymph node assay

Trends in Pharmacological Sciences

Volumn 22, Issue 6, 2001, Pages 264-265

  Basketter, David A ^a   Gerberick, G Frank ^b   Kimber, Ian ^c  

^a UNILEVER RESEARCH   (United Kingdom)

^b Human and Environmental Safety Division   (United States)

^c JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CONTACT ALLERGEN;

ACCURACY; ALLERGENICITY; ARTICLE; ASSAY; CHEMICAL ANALYSIS; CONTACT ALLERGY; GUINEA PIG; HAZARD; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT; SKIN SENSITIZATION; TECHNIQUE;

EID: 0035369507     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(00)01704-1     Document Type: Review

References (18)

1. Skin sensitization: A critical review of predictive test methods in animal and man
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3. An alternative strategy to the use of guinea pigs for the identification of skin sensitization hazard
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5. Local lymph node assay: Validation assessment for regulatory purposes
6. Statement on the validity of the local lymph node assay for skin sensitization testing
7. Investigation of lymph node cell proliferation as a possible immunological correlate of contact sensitizing potential
8. Contact sensitization: A new approach to risk assessment
9. A comparison of statistical approaches to derivation of EC3 values from local lymph node assay dose responses
10. Temporal stability of local lymph node assay responses to hexyl cinnamic aldehyde
11. Local lymph node assay responses to para-phenylenediamine: Intra- and inter-laboratory evaluations
12. Estimation of relative skin sensitizing potency using the local lymph node assay: A comparison of formaldehyde and glutaraldehyde
13. Skin sensitization risk assessment: A comparative evaluation of three isothiazolinone biocides
14. Use of the local lymph node assay for the estimation of relative contact allergenic potency
15. Contact allergenic potency: Correlation of human and local lymph node assay data
16. Human potency predictions for aldehydes using the local lymph node assay
17. The importance of exposure estimation in the assessment of skin sensitization risk