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Volumn 365, Issue 1537, 2010, Pages 185-205

Genome-wide scans for footprints of natural selection

Author keywords

Candidate genes; Genomes; genome wide selection scans; Human populations; Vertebrate species; Whole genome sequences

Indexed keywords

GENE; GENETIC STRUCTURE; GENETIC VARIATION; GENOME; HOMINID; MUTATION; NATURAL SELECTION; PHYLOGENETICS; SPECIES DIVERSITY;

EID: 75449100968     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2009.0219     Document Type: Review
Times cited : (261)

References (156)
  • 1
    • 0036911353 scopus 로고    scopus 로고
    • Interrogating a high-density SNP map for signitures of natural selection
    • DOI 10.1101/gr.631202
    • Akey, J. M., Zhang, G., Zhang, K., Jin, L. & Shriver, M. D. 2002 Interrogating a high-density SNP map for signatures of natural selection. Genome Res. 12, 1805-1814. (doi:10.1101/gr.631202) (Pubitemid 35469929)
    • (2002) Genome Research , vol.12 , Issue.12 , pp. 1805-1814
    • Akey, J.M.1    Zhang, G.2    Zhang, K.3    Jin, L.4    Shriver, M.D.5
  • 2
    • 33745279634 scopus 로고    scopus 로고
    • TRPV6 exhibits unusual patterns of polymorphism and divergence in worldwide populations
    • DOI 10.1093/hmg/ddl134
    • Akey, J. M., Swanson, W. J., Madeoy, J., Eberle, M. & Shriver, M. D. 2006 TRPV6 exhibits unusual patterns of polymorphism and divergence in worldwide populations. Hum. Mol. Genet 15, 2106-2113. (doi:10. 1093/hmg/dd1134) (Pubitemid 43923400)
    • (2006) Human Molecular Genetics , vol.15 , Issue.13 , pp. 2106-2113
    • Akey, J.M.1    Swanson, W.J.2    Madeoy, J.3    Eberle, M.4    Shriver, M.D.5
  • 4
    • 5044248542 scopus 로고    scopus 로고
    • Positive selection in MAOA gene is human exclusive: Determination of the putative amino acid change selected in the human lineage
    • DOI 10.1007/s00439-004-1179-6
    • Andres, A. M., Soldevila, M., Navarro, A., Kidd, K. K., Oliva, B. & Bertranpetit, J. 2004 Positive selection in MAOA gene is human exclusive: determination of the putative amino acid change selected in the human lineage. Hum. Genet 115, 377-386. (Pubitemid 39341711)
    • (2004) Human Genetics , vol.115 , Issue.5 , pp. 377-386
    • Andres, A.M.1    Soldevila, M.2    Navarro, A.3    Kidd, K.K.4    Oliva, B.5    Bertranpetit, J.6
  • 5
    • 34547782771 scopus 로고    scopus 로고
    • Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants
    • DOI 10.1086/519221
    • Ayodo, G., Price, A. L., Keinan, A., Ajwang, A., Otieno, M. F., Orago, A. S., Patterson, N. & Reich, D. 2007 Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants. Am. J. Hum. Genet. 81, 234-242. (doi:10.1086/519221) (Pubitemid 47236072)
    • (2007) American Journal of Human Genetics , vol.81 , Issue.2 , pp. 234-242
    • Ayodo, G.1    Price, A.L.2    Keinan, A.3    Ajwang, A.4    Otieno, M.F.5    Orago, A.S.S.6    Patterson, N.7    Reich, D.8
  • 6
    • 0036679358 scopus 로고    scopus 로고
    • A strong signature of balancing selection in the 5' cis-regulatory region of CCR5
    • doi:10.1073/ pnas.162046399
    • Bamshad, M. J. et al. 2002 A strong signature of balancing selection in the 5' cis-regulatory region of CCR5. Proc. Natl Acad. Sci. USA 99, 10539-10544. (doi:10.1073/ pnas.162046399)
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 10539-10544
    • Bamshad, M.J.1
  • 7
    • 0030218918 scopus 로고    scopus 로고
    • The genetics of pigmentation: From fancy genes to complex traits
    • doi:10.1016/0168-9525(96)10031-7
    • Barsh, G. S. 1996 The genetics of pigmentation: from fancy genes to complex traits. Trends Genet. 12, 299-305. (doi:10.1016/0168-9525(96)10031-7)
    • (1996) Trends Genet , vol.12 , pp. 299-305
    • Barsh, G.S.1
  • 8
    • 1642269679 scopus 로고    scopus 로고
    • Identifying adaptive genetic divergence among populations from genome scans
    • doi:10.1111/j.1365294X.2004.02125.x
    • Beaumont, M. A. & Balding, D. J. 2004 Identifying adaptive genetic divergence among populations from genome scans. Mol. Ecol. 13, 969-980. (doi:10.1111/j.1365294X.2004.02125.x)
    • (2004) Mol. Ecol , vol.13 , pp. 969-980
    • Beaumont, M.A.1    Balding, D.J.2
  • 9
    • 0030467524 scopus 로고    scopus 로고
    • Evaluating loci for use in the genetic analysis of population structure
    • doi:10.1098/rspb. 1996.0237
    • Beaumont, M. A. & Nichols, R. A. 1996 Evaluating loci for use in the genetic analysis of population structure. Proc. R. Soc. Lond B 163, 1619-1626. (doi:10.1098/rspb. 1996.0237)
    • (1996) Proc. R. Soc. Lond B , vol.163 , pp. 1619-1626
    • Beaumont, M.A.1    Nichols, R.A.2
  • 12
    • 0027940492 scopus 로고
    • G6PD deficiency
    • Beutler, E. 1994 G6PD deficiency. Blood 84, 3613-3636.
    • (1994) Blood , vol.84 , pp. 3613-3636
    • Beutler, E.1
  • 13
    • 33746237567 scopus 로고    scopus 로고
    • Genomic insights into positive selection
    • doi:10.1016/j.tig. 2006.06.005
    • Biswas, S. & Akey, J. M. 2006 Genomic insights into positive selection. Trends Genet. 11, 437-446. (doi:10.1016/j.tig. 2006.06.005)
    • (2006) Trends Genet , vol.11 , pp. 437-446
    • Biswas, S.1    Akey, J.M.2
  • 14
    • 0036106051 scopus 로고    scopus 로고
    • Algorithms for phylogenetic footprinting
    • doi:10.1089/10665270252935421
    • Blanchette, M., Schwikowski, B. & Tompa, M. 2002 Algorithms for phylogenetic footprinting. J. Comput Biol. 9, 211-223. (doi:10.1089/ 10665270252935421)
    • (2002) J. Comput Biol. , vol.9 , pp. 211-223
    • Blanchette, M.1    Schwikowski, B.2    Tompa, M.3
  • 15
    • 0025882118 scopus 로고
    • Structure of the chromosomal gene and cDNAs coding for lactase-phlorizin hydrolase in humans with adult-type hypolactasia or persistence of lactase
    • Boll,W.,Wagner,P.&Mantei,N. 1991StructureofthechromosomalgeneandcDNAscodingforlactasephlorizinhydrolaseinhu manswithadult-typehypolactasiaorpersistenceoflactase.Am.J.Hum.Genet.48,889-902. (Pubitemid21891633)
    • (1991) American Journal of Human Genetics , vol.48 , Issue.5 , pp. 889-902
    • Boll, W.1    Wagner, P.2    Mantei, N.3
  • 17
    • 0028053012 scopus 로고
    • Linkage disequilibrium in admixed populations: Applications in gene mapping
    • Briscoe,D.,Stephens,J.C.&O'Brien,S.J. 1994Linkagedisequilibriuminadmixedpopulations:applicationsingenemapping.J.Hered. 85,59-63.(Pubitemid24057427)
    • (1994) Journal of Heredity , vol.85 , Issue.1 , pp. 59-63
    • Briscoe, D.1    Stephens, J.C.2    O'Brien, S.J.3
  • 18
    • 27144539145 scopus 로고    scopus 로고
    • Natural selection on proteincoding genes in the human genome
    • doi:10.1038/nature04240
    • Bustamante, C. D. et al. 2005 Natural selection on proteincoding genes in the human genome. Nature 437, 1153-1157. (doi:10.1038/nature04240)
    • (2005) Nature , vol.437 , pp. 1153-1157
    • Bustamante, C.D.1
  • 21
    • 0032837669 scopus 로고    scopus 로고
    • Genetics of HIV-1 infection: Chemokine receptor CCR5 polymorphism and its consequences
    • DOI 10.1093/hmg/8.10.1939
    • Carrington, M., Dean, M., Martin, M. P. & O'Brien, S. J. 1999 Genetics of HIV-I infection: chemokine receptor CCR5 polymorphism and its consequences. Hum. Mol. Genet. 8, 1939-1945. (doi:10.1093/hmg/8.10.1939) (Pubitemid 29458672)
    • (1999) Human Molecular Genetics , vol.8 , Issue.10 , pp. 1939-1945
    • Carrington, M.1    Dean, M.2    Martin, M.P.3    O'Brien, S.J.4
  • 22
    • 0024209791 scopus 로고
    • Admixture as a tool for finding linked genes and detecting that difference from allelic association between loci
    • DOI 10.1073/pnas.85.23.9119
    • Chakraborty, R. & Weiss, K. M. 1988 Admixture as a tool for finding linked genes and detecting that difference from allelic association between loci. Proc. Natl Acad. Sci. USA 85, 9119-9123. (doi:10.1073/pnas.85.23. 9119) (Pubitemid 19001851)
    • (1988) Proceedings of the National Academy of Sciences of the United States of America , vol.85 , Issue.23 , pp. 9119-9123
    • Chakraborty, R.1    Weiss, K.M.2
  • 23
    • 0028985434 scopus 로고
    • The coding sequence of Duffy blood group gene in humans and simians: Restriction fragment length polymorphism, antibody and malarial parasite specificities, and expression in nonerythroid tissues in Duffy-negative individuals
    • Chaudhuri, A., Polyakova, J., Zbrzezna, V. & Pogo, A. O. 1995 The coding sequence of Duffy blood group gene in humans and simians: restriction fragment length polymorphism, antibody and malarial parasite specificities, and expression in nonerythroid tissues in Duffy-negative individuals. Blood 85, 615-621.
    • (1995) Blood , vol.85 , pp. 615-621
    • Chaudhuri, A.1    Polyakova, J.2    Zbrzezna, V.3    Pogo, A.O.4
  • 24
    • 33644860353 scopus 로고    scopus 로고
    • The testis-specific apoptosis related gene TTL.6 underwent adaptive evolution in the lineage leading to humans
    • DOI 10.1016/j.gene.2005.11.014, PII S0378111905007043
    • Chen, X. H., Shi, H., Liu, X. L. & Su, B. 2006 The testisspecific apoptosis related gene TTL. 6 underwent adaptive evolution in the lineage leading to humans. Gene 370, 58-63. (doi:10.1016/j.gene.2005.11.014) (Pubitemid 43375900)
    • (2006) Gene , vol.370 , Issue.1-2 , pp. 58-63
    • Chen, X.-H.1    Shi, H.2    Liu, X.-L.3    Su, B.4
  • 26
    • 33244494690 scopus 로고    scopus 로고
    • Rapid evolution and gene-specific patterns of selection for three genes of spermatogenesis in Drosophila
    • DOI 10.1093/molbev/msj074
    • Civetta, A., Rajakumar, S. A., Brouwers, B. & Bacik, J. P. 2006 Rapid evolution and gene-specific patterns of selection for three genes of spermatogenesis in Drosophila. Mol. Biol. Evol. 23, 655-662. (doi:10.1093/molbev/msj074) (Pubitemid 43278277)
    • (2006) Molecular Biology and Evolution , vol.23 , Issue.3 , pp. 655-662
    • Civetta, A.1    Rajakumar, S.A.2    Brouwers, B.3    Bacik, J.P.4
  • 27
    • 48249109932 scopus 로고    scopus 로고
    • Structurally different alleles of the ath-MIR824 microRNA precursor are maintained at high frequency in Arabidopsis thaliana
    • doi: 10.1073/pnas.0803218105
    • de Meaux, J., Hu, J.-Y., Tartler, U. & Goebel, U. 2008 Structurally different alleles of the ath-MIR824 microRNA precursor are maintained at high frequency in Arabidopsis thaliana. Proc. Natl Acad. Sci. USA 105, 8994-8999. (doi: 10.1073/pnas.0803218105)
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 8994-8999
    • De Meaux, J.1    Hu, J.-Y.2    Tartler, U.3    Goebel, U.4
  • 28
    • 0001633495 scopus 로고    scopus 로고
    • Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia growth and development study, multicenter AIDS cohort study, multicenter hemophilia cohort study, San Francisco City Cohort, AUVE study
    • doi:10.1126/science.273.5283.1856
    • Dean, M. et al. 1996 Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, AUVE Study. Science 273, 1856-1862. (doi:10.1126/science.273.5283.1856)
    • (1996) Science , vol.273 , pp. 1856-1862
    • Dean, M.1
  • 29
    • 18244373484 scopus 로고    scopus 로고
    • Evidence of positive selection acting at the human dopamine receptor D4 gene locus
    • doi:10.1073/pnas. 012464099
    • Ding, Y. C. et al. 2002 Evidence of positive selection acting at the human dopamine receptor D4 gene locus. Proc. Natl Acad. Sci. USA 99, 309-314. (doi:10.1073/pnas. 012464099)
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 309-314
    • Ding, Y.C.1
  • 30
    • 0037418588 scopus 로고    scopus 로고
    • Molecular genetics and evolution of melanism in the cat family
    • DOI 10.1016/S0960-9822(03)00128-3, PII S0960982203001283
    • Eizirik, E., Yuhki, N., Johnson, W. E., Menotti-Raymond, M., Hannah, S. S. & O'Brien, S. J. 2003 Molecular genetics and evolution of melanism in the cat family. Curr. Biol. 13, 448-453. (doi:10.1016/S0960-9822(03) 00128-3) (Pubitemid 36280466)
    • (2003) Current Biology , vol.13 , Issue.5 , pp. 448-453
    • Eizirik, E.1    Yuhki, N.2    Johnson, W.E.3    Menotti-Raymond, M.4    Hannah, S.S.5    O'Brien, S.J.6
  • 31
    • 0037158715 scopus 로고    scopus 로고
    • Molecular evolution of FOXP2, a gene involved in speech and language
    • DOI 10.1038/nature01025
    • Enard, W., Przeworski, M., Fisher, S. E., Lai, C. S., Wiebe, V., Kitano, T., Monaco, A. P. & Paabo, S. 2002 Molecular evolution of FOXP2, a gene involved in speech and language. Nature 418, 869-872. (doi:10. 1038/nature01025) (Pubitemid 34966304)
    • (2002) Nature , vol.418 , Issue.6900 , pp. 869-872
    • Enard, W.1    Przeworski, M.2    Fisher, S.E.3    Lai, C.S.L.4    Wiebe, V.5    Kitano, T.6    Monaco, A.P.7    Paabo, S.8
  • 32
    • 0036479030 scopus 로고    scopus 로고
    • Identification of a variant associated with adult-type hypolactasia
    • DOI 10.1038/ng826
    • Enattah, N. S., Sahi, T., Savilahti, E., Terwilliger, J. D., Peltonen, L. & Jarvela, I. 2002 Identification of a variant associated with adult-type hypolactasia. Nat. Genet 30, 233-237. (doi:10.1038/ng826) (Pubitemid 34887722)
    • (2002) Nature Genetics , vol.30 , Issue.2 , pp. 233-237
    • Enattah, N.S.1    Sahi, T.2    Savilahti, E.3    Terwilliger, J.D.4    Peltonen, L.5    Jarvela, I.6
  • 33
    • 14544308463 scopus 로고    scopus 로고
    • 13910 is associated with bone fractures in very old age
    • DOI 10.1111/j.1532-5415.2005.53014.x
    • Enattah, N. S., Sulkava, R., Halonen, P., Kontula, K. & Jarvela, I. 2005 Genetic variant of lactase-persistent C/T-13910 is associated with bone fractures in very old age. J. Am. Geriatr. Soc. 53, 79-82. (doi:10.1111/j.1532- 5415.2005.53014.x) (Pubitemid 41647635)
    • (2005) Journal of the American Geriatrics Society , vol.53 , Issue.1 , pp. 79-82
    • Enattah, N.S.1    Sulkava, R.2    Halonen, P.3    Kontula, K.4    Jarvela, I.5
  • 35
    • 33744513368 scopus 로고    scopus 로고
    • Molecular evolution of the brain size regulator genes CDK5RAP2 and CENPJ
    • doi:10.1016/j.gene.2006.02.019
    • Evans, P. D., Vallender, E. J. & Lahn, B. T. 2006b Molecular evolution of the brain size regulator genes CDK5RAP2 and CENPJ. Gene 375, 75-79. (doi:10.1016/j.gene.2006.02.019)
    • (2006) Gene , vol.375 , pp. 75-79
    • Evans, P.D.1    Vallender, E.J.2    Lahn, B.T.3
  • 36
    • 0033911640 scopus 로고    scopus 로고
    • Hitchhiking under positive Darwinian selection
    • Fay, J. C. & Wu, I. 2000 Hitchhiking under positive Darwinian selection. Genetics 155, 1405-1413.
    • (2000) Genetics , vol.155 , pp. 1405-1413
    • Fay, J.C.1    Wu, I.2
  • 37
    • 34548135234 scopus 로고    scopus 로고
    • MC1R: Three novel variants identified in a malignant melanoma association study in the Spanish population
    • doi:10.1093/carcin/ bgm084
    • Fernandez, L., Milne, R., Bravo, J., Lopez, J., Aviles, J., Longo, M., Benitez, J., Lazaro, P. & Ribas, G. 2007 MC1R: Three novel variants identified in a malignant melanoma association study in the Spanish population. Carcinogenesis 28, 1659-1664. (doi:10.1093/carcin/ bgm084)
    • (2007) Carcinogenesis , vol.28 , pp. 1659-1664
    • Fernandez, L.1    Milne, R.2    Bravo, J.3    Lopez, J.4    Aviles, J.5    Longo, M.6    Benitez, J.7    Lazaro, P.8    Ribas, G.9
  • 38
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • doi:10.1038/nature06258
    • Frazer, K. A. et al. 2007 A second generation human haplotype map of over 3.1 million SNPs. Nature 449, 851-861. (doi:10.1038/nature06258)
    • (2007) Nature , vol.449 , pp. 851-861
    • Frazer, K.A.1
  • 39
    • 0027453041 scopus 로고
    • Statistical tests of neutrality of mutations
    • Fu, Y. X. & Li, W. H. 1993 Statistical tests of neutrality of mutations. Genetics 133, 693-709.
    • (1993) Genetics , vol.133 , pp. 693-709
    • Fu, Y.X.1    Li, W.H.2
  • 41
    • 0345166037 scopus 로고    scopus 로고
    • Evaluating plague and smallpox as historical selective pressures for the CCR5Delta 32 HIV-resistance allele
    • doi:10.1073/pnas.2435085100
    • Galvani, A. P. & Slatkin, M. 2003 Evaluating plague and smallpox as historical selective pressures for the CCR5Delta 32 HIV-resistance allele. Proc. Natl Acad. Sci. USA 100, 15 276-15 279. (doi:10.1073/pnas.2435085100)
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 15276-15279
    • Galvani, A.P.1    Slatkin, M.2
  • 42
    • 0028885341 scopus 로고
    • Multiple glucose 6-phosphate dehydrogenasedeficient variants correlate with malaria endemicity in the Vanuatu archipelago (southwestern Pacific)
    • Ganczakowskd, M., Town, M., Bowden, D. K., Vulliamy, T. J., Kaneko, A., Clegg, J. B., Weatherall, D. J. & Luzzatto, L. 1995 Multiple glucose 6-phosphate dehydrogenasedeficient variants correlate with malaria endemicity in the Vanuatu archipelago (southwestern Pacific). Am. J. Hum. Genet 56, 294-301.
    • (1995) Am. J. Hum. Genet , vol.56 , pp. 294-301
    • Ganczakowskd, M.1    Town, M.2    Bowden, D.K.3    Vulliamy, T.J.4    Kaneko, A.5    Clegg, J.B.6    Weatherall, D.J.7    Luzzatto, L.8
  • 44
    • 85020804279 scopus 로고    scopus 로고
    • A proposition to obtain whole genome sequence for 10,000 vertebrate species
    • Genome 10K Community of Scientists: Genome 10K, (G1KCOS). In press.
    • Genome 10K Community of Scientists: Genome 10K, (G1KCOS). In press. A proposition to obtain whole genome sequence for 10,000 vertebrate species. J. Hered.
    • J. Hered.
  • 45
    • 34247647905 scopus 로고    scopus 로고
    • Comprehensive evaluation of allele frequency differences of MC1R variants across populations
    • doi:10.1002/humu.20476
    • Gerstenblith, M. R., Goldstein, A. M., Fargnoli, M. C., Peris, K. & Landi, M. T. 2007 Comprehensive evaluation of allele frequency differences of MC1R variants across populations. Hum. Mutat 28, 495-505. (doi:10.1002/humu. 20476)
    • (2007) Hum. Mutat , vol.28 , pp. 495-505
    • Gerstenblith, M.R.1    Goldstein, A.M.2    Fargnoli, M.C.3    Peris, K.4    Landi, M.T.5
  • 46
    • 0037154208 scopus 로고    scopus 로고
    • Evidence for positive selection and population structure at the human MAO-A gene
    • doi:10.1073/pnas. 022614799
    • Gilad, Y., Rosenberg, S., Przeworski, M., Lancet, D. & Skorecki, K. 2002 Evidence for positive selection and population structure at the human MAO-A gene. Proc. Natl Acad. Sci. USA 99, 862-867. (doi:10.1073/pnas. 022614799)
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 862-867
    • Gilad, Y.1    Rosenberg, S.2    Przeworski, M.3    Lancet, D.4    Skorecki, K.5
  • 48
    • 19244384846 scopus 로고    scopus 로고
    • Global survey of genetic variation in CCR5, RANTES, and MIP-1alpha: Impact on the epidemiology of the HIV-1 pandemic
    • doi:10.1073/pnas.091056898
    • Gonzalez, E. et al. 2001 Global survey of genetic variation in CCR5, RANTES, and MIP-1alpha: impact on the epidemiology of the HIV-1 pandemic. Proc. Natl Acad. Sci. USA 98, 5199-5204. (doi:10.1073/pnas.091056898)
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 5199-5204
    • Gonzalez, E.1
  • 49
    • 0042490798 scopus 로고    scopus 로고
    • Evidence for selective advantage of pathogenic FGFR2 mutations in the male germ line
    • doi:10.1126/science.1085710
    • Goriely, A., McVean, G. A., Rojmyr, M., Ingemarsson, B. & Wilkie, A. O. 2003 Evidence for selective advantage of pathogenic FGFR2 mutations in the male germ line. Science 301, 643-646. (doi:10.1126/science.1085710)
    • (2003) Science , vol.301 , pp. 643-646
    • Goriely, A.1    McVean, G.A.2    Rojmyr, M.3    Ingemarsson, B.4    Wilkie, A.O.5
  • 50
    • 17844393110 scopus 로고    scopus 로고
    • Gain-offunction amino acid substitutions drive positive selection of FGFR2 mutations in human spermatogonia
    • doi:10.1073/pnas.0500267102
    • Goriely, A., McVean, G. A., van Pelt, A. M., O'Rourke, A. W., Wall, S. A., de Rooij, D. G. & Wilkie, A. O. 2005 Gain-offunction amino acid substitutions drive positive selection of FGFR2 mutations in human spermatogonia. Proc. Natl Acad Sci. USA 102, 6051-6056. (doi:10.1073/pnas. 0500267102)
    • (2005) Proc. Natl Acad Sci. USA , vol.102 , pp. 6051-6056
    • Goriely, A.1    McVean, G.A.2    Van Pelt, A.M.3    O'Rourke, A.W.4    Wall, S.A.5    De Rooij, D.G.6    Wilkie, A.O.7
  • 51
    • 0030917736 scopus 로고    scopus 로고
    • From malaria to chemokine receptor: The emerging physiologic role of the Duffy blood group antigen
    • Hadley, T. J. & Peiper, S. C. 1997 From malaria to chemokine receptor: the emerging physiologic role of the Duffy blood group antigen. Blood 89, 3077-3091.
    • (1997) Blood , vol.89 , pp. 3077-3091
    • Hadley, T.J.1    Peiper, S.C.2
  • 52
    • 0033911892 scopus 로고    scopus 로고
    • Detection of the signature of natural selection in humans: Evidence from the Duffy blood group locus
    • doi: 10.1086/302879
    • Hamblin, M. T & Di Rienzo, A. 2000 Detection of the signature of natural selection in humans: evidence from the Duffy blood group locus. Am. J. Hum. Genet 66, 1669-1679. (doi: 10.1086/302879)
    • (2000) Am. J. Hum. Genet , vol.66 , pp. 1669-1679
    • Hamblin, M.T.1    Di Rienzo, A.2
  • 53
    • 0036157464 scopus 로고    scopus 로고
    • Complex signatures of natural selection at the Duffy blood group locus
    • doi: 10.1086/338628
    • Hamblin, M. T., Thompson, E. E. & Di Rienzo, A. 2002 Complex signatures of natural selection at the Duffy blood group locus. Am. J. Hum. Genet 70, 369-383. (doi: 10.1086/338628)
    • (2002) Am. J. Hum. Genet , vol.70 , pp. 369-383
    • Hamblin, M.T.1    Thompson, E.E.2    Di Rienzo, A.3
  • 54
    • 0033927855 scopus 로고    scopus 로고
    • Evidence for variable selective pressures at MC1R
    • doi: 10.1086/302863
    • Harding, R. M. et al. 2000 Evidence for variable selective pressures at MC1R. Am. J. Hum. Genet. 66, 1351-1361. (doi: 10.1086/302863)
    • (2000) Am. J. Hum. Genet. , vol.66 , pp. 1351-1361
    • Harding, R.M.1
  • 55
    • 0035873844 scopus 로고    scopus 로고
    • Human populations show reduced DNA sequence variation at the factor IX locus
    • doi:10.1016/S09609822(01)00223-8
    • Harris, E. E. & Hey, J. 2001 Human populations show reduced DNA sequence variation at the factor IX locus. Curr. Biol. 11, 774-778. (doi:10.1016/S09609822(01)00223-8)
    • (2001) Curr. Biol. , vol.11 , pp. 774-778
    • Harris, E.E.1    Hey, J.2
  • 56
    • 0027421312 scopus 로고
    • Regional localization of the lactase-phlorizin hydrolase gene, LCT, to chromosome 2q21
    • doi: 10.1111/j.1469-1809.1993.tb01593.x
    • Harvey, C. B., Fox, M. F., Jeggo, P. A., Mantei, N., Povey, S. & Swallow, D. M. 1993 Regional localization of the lactase-phlorizin hydrolase gene, LCT, to chromosome 2q21. Ann. Hum. Genet. 57, 179-185. (doi: 10.1111/j.1469-1809.1993.tb01593.x)
    • (1993) Ann. Hum. Genet. , vol.57 , pp. 179-185
    • Harvey, C.B.1    Fox, M.F.2    Jeggo, P.A.3    Mantei, N.4    Povey, S.5    Swallow, D.M.6
  • 57
    • 0035504443 scopus 로고    scopus 로고
    • Functional variation of MClR alleles from red-haired individuals
    • doi:10.1093/hmg/10.21.2397
    • Healy, E., Jordan, S. A., Budd, P. S., Suffolk, R., Rees, J. L. & Jackson, I. J. 2001 Functional variation of MClR alleles from red-haired individuals. Hum. Mol. Genet. 10, 2397-2402. (doi:10.1093/hmg/10.21.2397)
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2397-2402
    • Healy, E.1    Jordan, S.A.2    Budd, P.S.3    Suffolk, R.4    Rees, J.L.5    Jackson, I.J.6
  • 59
    • 0023339852 scopus 로고
    • A test of neutral molecular evolution based on nucleotide data
    • Hudson, R. R., Kreitman, M. & Aguade, M. 1987 A test of neutral molecular evolution based on nucleotide data. Genetics 116, 153-159.
    • (1987) Genetics , vol.116 , pp. 153-159
    • Hudson, R.R.1    Kreitman, M.2    Aguade, M.3
  • 60
    • 0001359013 scopus 로고    scopus 로고
    • Natural selection and the evolutionary history of major histocompatibility complex loci
    • Hughes, A. L. & Yeager, M. 1998 Natural selection and the evolutionary history of major histocompatibility complex loci. Front. Biosci. 3, d509-d516.
    • (1998) Front. Biosci. , vol.3
    • Hughes, A.L.1    Yeager, M.2
  • 61
    • 21344467949 scopus 로고    scopus 로고
    • Detection of the CCR5-Delta32 HIV resistance gene in Bronze Age skeletons
    • doi:10.1038/sj.gene.6364172
    • Hummel, S., Schmidt, D., Kremeyer, B., Herrmann, B. & Oppermann, M. 2005 Detection of the CCR5-Delta32 HIV resistance gene in Bronze Age skeletons. Genes Immun. 6, 371-374. (doi:10.1038/sj.gene.6364172)
    • (2005) Genes Immun. , vol.6 , pp. 371-374
    • Hummel, S.1    Schmidt, D.2    Kremeyer, B.3    Herrmann, B.4    Oppermann, M.5
  • 62
    • 0344500841 scopus 로고    scopus 로고
    • A scan for linkage disequilibrium across the human genome
    • Huttley, G. A., Smith, M. W., Carrington, M. & O'Brien, S. J. 1999 A scan for linkage disequilibrium across the human genome. Genetics 152, 1711-1722.
    • (1999) Genetics , vol.152 , pp. 1711-1722
    • Huttley, G.A.1    Smith, M.W.2    Carrington, M.3    O'Brien, S.J.4
  • 63
    • 0038050991 scopus 로고    scopus 로고
    • DNA polymorphism and selection at the melanocortin-1 receptor gene in normally pigmented southern African individuals
    • doi:10.1111/j.1749-6632.2003.tb03193.x
    • John, P. R., Makova, K., Li, W. H., Jenkins, T. & Ramsay, M. 2003 DNA polymorphism and selection at the melanocortin-1 receptor gene in normally pigmented southern African individuals. Ann. N Y. Acad. Sci. 994, 299-306. (doi:10.1111/j.1749-6632.2003.tb03193.x)
    • (2003) Ann. N Y. Acad. Sci. , vol.994 , pp. 299-306
    • John, P.R.1    Makova, K.2    Li, W.H.3    Jenkins, T.4    Ramsay, M.5
  • 64
    • 33749481705 scopus 로고    scopus 로고
    • Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma
    • doi: 10.1158/00085472.CAN-06-1634
    • Kanetsky, P. A. et al. 2006 Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma. Cancer Res. 66, 9330-9337. (doi: 10.1158/00085472.CAN-06-1634)
    • (2006) Cancer Res. , vol.66 , pp. 9330-9337
    • Kanetsky, P.A.1
  • 65
    • 52949145597 scopus 로고    scopus 로고
    • Positive selection in the human genome: From genome scans to biological significance
    • doi:10.1146/annurev.genom.9.081307.164411
    • Kelley, J. L. & Swanson, W. J. 2008 Positive selection in the human genome: from genome scans to biological significance. Annu. Rev. Genomics Hum. Genet. 9, 143-160. (doi:10.1146/annurev.genom.9.081307.164411)
    • (2008) Annu. Rev. Genomics Hum. Genet. , vol.9 , pp. 143-160
    • Kelley, J.L.1    Swanson, W.J.2
  • 67
    • 22544441601 scopus 로고    scopus 로고
    • How malaria has affected the human genome and what human genetics can teach us about malaria
    • doi: 10.1086/432519
    • Kwiatkowski, D. P. 2005 How malaria has affected the human genome and what human genetics can teach us about malaria. Am. J. Hum. Genet. 11, 171-192. (doi: 10.1086/432519)
    • (2005) Am. J. Hum. Genet. , vol.11 , pp. 171-192
    • Kwiatkowski, D.P.1
  • 68
    • 29144485743 scopus 로고    scopus 로고
    • SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans
    • doi:10.1126/science.1116238
    • Lamason, R. L. et al. 2005 SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans. Science 310, 1782-1786. (doi:10.1126/science.1116238)
    • (2005) Science , vol.310 , pp. 1782-1786
    • Lamason, R.L.1
  • 69
    • 2042437650 scopus 로고    scopus 로고
    • International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome
    • doi: 10.1038/35057062
    • Lander et al 2001 International Human Genome Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 409, 860-921. (doi: 10.1038/35057062)
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander1
  • 70
    • 0033912677 scopus 로고    scopus 로고
    • Significant admixture linkage disequilibrium across 30 cM around the FY locus in African Americans
    • doi:10.1086/302820
    • Lautenberger, J. A., Stephens, J. C., O'Brien, S. J. & Smith, M. W. 2000 Significant admixture linkage disequilibrium across 30 cM around the FY locus in African Americans. Am. J. Hum. Genet. 66, 969-978. (doi:10.1086/302820)
    • (2000) Am. J. Hum. Genet. , vol.66 , pp. 969-978
    • Lautenberger, J.A.1    Stephens, J.C.2    O'Brien, S.J.3    Smith, M.W.4
  • 72
    • 29644439954 scopus 로고    scopus 로고
    • T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro
    • doi:10.1093/hmg/ddi418
    • Lewinsky, R. H., Jensen, T. G., Moller, J., Stensballe, A., Olsen, J. & Troelsen, J. T 2005 T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro. Hum. Mol. Genet 14, 3945-3953. (doi:10.1093/hmg/ddi418)
    • (2005) Hum. Mol. Genet , vol.14 , pp. 3945-3953
    • Lewinsky, R.H.1    Jensen, T.G.2    Moller, J.3    Stensballe, A.4    Olsen, J.5    Troelsen, J.T.6
  • 73
    • 0015879546 scopus 로고
    • Distribution of gene frequency as a test of the theory of the selective neutrality of polymorphisms
    • Lewontin, R. C. & Krakauer, J. 1973 Distribution of gene frequency as a test of the theory of the selective neutrality of polymorphisms. Genetics 74, 175-195.
    • (1973) Genetics , vol.74 , pp. 175-195
    • Lewontin, R.C.1    Krakauer, J.2
  • 74
    • 0016515491 scopus 로고
    • Letters to the editors: Testing the heterogeneity of F values
    • Lewontin, R. C. & Krakauer, J. 1975 Letters to the editors: testing the heterogeneity of F values. Genetics 80, 397-398.
    • (1975) Genetics , vol.80 , pp. 397-398
    • Lewontin, R.C.1    Krakauer, J.2
  • 75
    • 6844240236 scopus 로고    scopus 로고
    • The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe
    • doi:10.1093/hmg/7.3.399
    • Libert, F. et al. 1998 The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe. Hum. Mol. Genet 7,399-406. (doi:10.1093/hmg/7.3.399)
    • (1998) Hum. Mol. Genet , vol.7 , pp. 399-406
    • Libert, F.1
  • 76
    • 28644447707 scopus 로고    scopus 로고
    • Genome sequence, comparative analysis and haplotype structure of the domestic dog
    • doi:10.1038/nature04338
    • Lindblad-Toh, K. et al. 2005 Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature 438, 803-819. (doi:10.1038/nature04338)
    • (2005) Nature , vol.438 , pp. 803-819
    • Lindblad-Toh, K.1
  • 77
    • 0021232493 scopus 로고
    • The Duffy blood groups, vivax malaria, and malaria selection in human populations: A review
    • Livingstone, F. B. 1984 The Duffy blood groups, vivax malaria, and malaria selection in human populations: a review. Hum. Biol. 56, 413-425.
    • (1984) Hum. Biol. , vol.56 , pp. 413-425
    • Livingstone, F.B.1
  • 78
    • 25144477342 scopus 로고    scopus 로고
    • Worldwide polymorphism at the MC1R locus and normal pigmentation variation in humans
    • doi:10.1016/j. peptides.2004.12.032
    • Makova, K. & Norton, H. 2005 Worldwide polymorphism at the MC1R locus and normal pigmentation variation in humans. Peptides 26, 1901-1908. (doi:10.1016/j. peptides.2004.12.032)
    • (2005) Peptides , vol.26 , pp. 1901-1908
    • Makova, K.1    Norton, H.2
  • 79
    • 0034924340 scopus 로고    scopus 로고
    • Human DNA sequence variation in a 6.6-kb region containing the melanocortin 1 receptor promoter
    • Makova, K. D., Ramsay, M., Jenkins, T & Li, W. H. 2001 Human DNA sequence variation in a 6.6-kb region containing the melanocortin 1 receptor promoter. Genetics 158, 1253-1268.
    • (2001) Genetics , vol.158 , pp. 1253-1268
    • Makova, K.D.1    Ramsay, M.2    Jenkins, T.3    Li, W.H.4
  • 80
    • 0030337794 scopus 로고    scopus 로고
    • A missense mutation in the gene for melanocytestimulating hormone receptor (MC1R) is associated with the chestnut coat color in horses
    • doi:10.1007/s003359900264
    • Marklund, L., Moller, M. J., Sandberg, K. & Andersson, L. 1996 A missense mutation in the gene for melanocytestimulating hormone receptor (MC1R) is associated with the chestnut coat color in horses. Mamm. Genome 7, 895-899. (doi:10.1007/s003359900264)
    • (1996) Mamm. Genome , vol.7 , pp. 895-899
    • Marklund, L.1    Moller, M.J.2    Sandberg, K.3    Andersson, L.4
  • 81
    • 0032484088 scopus 로고    scopus 로고
    • Genetic acceleration of AIDS progression by a promoter variant of CCR5
    • doi:10.1126/science.282.5395.1907
    • Martin, M. P. et al. 1998 Genetic acceleration of AIDS progression by a promoter variant of CCR5. Science 282, 1907-1911. (doi:10.1126/science.282.5395. 1907)
    • (1998) Science , vol.282 , pp. 1907-1911
    • Martin, M.P.1
  • 82
    • 0016220238 scopus 로고
    • The hitchhiking effect of a favorable gene
    • Maynard Smith, J. & Haigh, J. 1974 The hitchhiking effect of a favorable gene. Genet Res 23, 23-35.
    • (1974) Genet Res , vol.23 , pp. 23-35
    • Maynard Smith, J.1    Haigh, J.2
  • 84
    • 0026428610 scopus 로고
    • Adaptive protein evolution at the Adh locus in Drosophila
    • doi: 10.1038/351652a0
    • McDonald, J. H. & Kreitman, M. 1991 Adaptive protein evolution at the Adh locus in Drosophila. Nature 351, 652-654. (doi: 10.1038/351652a0)
    • (1991) Nature , vol.351 , pp. 652-654
    • McDonald, J.H.1    Kreitman, M.2
  • 86
    • 24344500211 scopus 로고    scopus 로고
    • Initial sequence of the chimpanzee genome and comparison with the human genome
    • Mikkelsen, T. S. et al. 2005 Initial sequence of the chimpanzee genome and comparison with the human genome. Nature 437, 69-87.
    • (2005) Nature , vol.437 , pp. 69-87
    • Mikkelsen, T.S.1
  • 87
    • 25444533019 scopus 로고    scopus 로고
    • Host switch leads to emergence of Plasmodium vivax malaria in humans
    • doi:10.1093/molbev/msi160
    • Mu, J. et al. 2005 Host switch leads to emergence of Plasmodium vivax malaria in humans. Mol. Biol. Evol. 11, 1686-1693. (doi:10.1093/molbev/msi160)
    • (2005) Mol. Biol. Evol. , vol.11 , pp. 1686-1693
    • Mu, J.1
  • 88
    • 2442673931 scopus 로고    scopus 로고
    • The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in Africans
    • doi:10.1086/421050
    • Mulcare, C. A., Weale, M. E., Jones, A. L., Connell, B., Zeitlyn, D., Tarekegn, A., Swallow, D. M., Bradman, N. & Thomas, M. G. 2004 The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in Africans. Am. J. Hum. Genet 74, 1102-1110. (doi:10.1086/421050)
    • (2004) Am. J. Hum. Genet , vol.74 , pp. 1102-1110
    • Mulcare, C.A.1    Weale, M.E.2    Jones, A.L.3    Connell, B.4    Zeitlyn, D.5    Tarekegn, A.6    Swallow, D.M.7    Bradman, N.8    Thomas, M.G.9
  • 89
    • 0030679633 scopus 로고    scopus 로고
    • The human CC chemokine receptor 5 (CCR5) gene. Multiple transcripts with 5'-end heterogeneity, dual promoter usage, and evidence for polymorphisms within the regulatory regions and noncoding exons
    • doi:10.1074/jbc. 272.49.30662
    • Mummidi, S., Ahuja, S. S., McDaniel, B. L. & Ahuja, S. K. 1997 The human CC chemokine receptor 5 (CCR5) gene. Multiple transcripts with 5'-end heterogeneity, dual promoter usage, and evidence for polymorphisms within the regulatory regions and noncoding exons. J. Biol. Chem. 272, 30662-30671. (doi:10.1074/jbc. 272.49.30662)
    • (1997) J. Biol. Chem. , vol.272 , pp. 30662-30671
    • Mummidi, S.1    Ahuja, S.S.2    McDaniel, B.L.3    Ahuja, S.K.4
  • 90
    • 0033899763 scopus 로고    scopus 로고
    • Contrasting evolutionary histories of two introns of the duchenne muscular dystrophy gene, Dmd, in humans
    • Nachman, M. W. & Crowell, S. L. 2000 Contrasting evolutionary histories of two introns of the duchenne muscular dystrophy gene, Dmd, in humans. Genetics 155, 1855-1864.
    • (2000) Genetics , vol.155 , pp. 1855-1864
    • Nachman, M.W.1    Crowell, S.L.2
  • 91
    • 2342459066 scopus 로고    scopus 로고
    • Natural selection and population history in the human angiotensinogen gene (AGT): 736 complete AGT sequences in chromosomes from around the world
    • doi:10. 1086/420793
    • Nakajima, T. et al. 2004 Natural selection and population history in the human angiotensinogen gene (AGT): 736 complete AGT sequences in chromosomes from around the world. Am. J. Hum. Genet. 74, 898-916. (doi:10. 1086/420793)
    • (2004) Am. J. Hum. Genet. , vol.74 , pp. 898-916
    • Nakajima, T.1
  • 92
    • 0016516814 scopus 로고
    • Lewontin-Krakauer test for neutral genes
    • Nei, M. & Maruyama, T 1975 Lewontin-Krakauer test for neutral genes. Genetics 80, 395.
    • (1975) Genetics , vol.80 , pp. 395
    • Nei, M.1    Maruyama, T.2
  • 94
    • 0042991419 scopus 로고    scopus 로고
    • Correcting for ascertainment biases when analyzing SNP data: Applications to the estimation of linkage disequilibrium
    • doi:10.1016/S0040-5809(03) 00005-4
    • Nielsen, R. & Signorovitch, J. 2003 Correcting for ascertainment biases when analyzing SNP data: applications to the estimation of linkage disequilibrium. Theor. Popul. Biol. 63, 245-255. (doi:10.1016/S0040-5809(03) 00005-4)
    • (2003) Theor. Popul. Biol. , vol.63 , pp. 245-255
    • Nielsen, R.1    Signorovitch, J.2
  • 95
    • 0031972161 scopus 로고    scopus 로고
    • Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene
    • Nielsen, R. & Yang, Z. 1998 Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene. Genetics 148, 929-936.
    • (1998) Genetics , vol.148 , pp. 929-936
    • Nielsen, R.1    Yang, Z.2
  • 98
    • 27844602105 scopus 로고    scopus 로고
    • The geographic spread of the CCR5 Delta32 HIV-resistance allele
    • doi:10.1371/joumal.pbio. 0030339
    • Novembre, J., Galvani, A. P. & Slatkin, M. 2005 The geographic spread of the CCR5 Delta32 HIV-resistance allele. PLoS Biol. 3, e339. (doi:10.1371/joumal.pbio. 0030339)
    • (2005) PLoS Biol. , vol.3
    • Novembre, J.1    Galvani, A.P.2    Slatkin, M.3
  • 99
    • 0033647217 scopus 로고    scopus 로고
    • The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS
    • doi:10.1034/j.1600-065X.2000.17710.x
    • O'Brien, S. J. & Moore, J. P. 2000 The effect of genetic variation in chemokines and their receptors on HIV transmission and progression to AIDS. Immunol. Rev. 177, 99-111. (doi:10.1034/j.1600-065X.2000.17710.x)
    • (2000) Immunol. Rev. , vol.177 , pp. 99-111
    • O'Brien, S.J.1    Moore, J.P.2
  • 100
    • 2642563503 scopus 로고    scopus 로고
    • Human genes that limit AIDS
    • doi:10.1038/ng1369
    • O'Brien, S. J. & Nelson, G. W 2004 Human genes that limit AIDS. Nat. Genet. 36, 565-574. (doi:10.1038/ng1369)
    • (2004) Nat. Genet. , vol.36 , pp. 565-574
    • O'Brien, S.J.1    Nelson, G.W.2
  • 101
    • 45149116551 scopus 로고    scopus 로고
    • Selection in the making: A worldwide survey of haplotypic diversity around a causative mutation in porcine IGF2
    • doi: 10.1534/genetics. 107.084269
    • Ojeda, A. et al. 2008 Selection in the making: a worldwide survey of haplotypic diversity around a causative mutation in porcine IGF2. Genetics 178, 1639-1652. (doi: 10.1534/genetics. 107.084269)
    • (2008) Genetics , vol.178 , pp. 1639-1652
    • Ojeda, A.1
  • 102
    • 0141702274 scopus 로고    scopus 로고
    • Lactase persistence DNA variant enhances lactase promoter activity in vitro: Functional role as a cis regulatory element
    • doi:10.1093/hmg/ddg244
    • Olds, L. C. & Sibley, E. 2003 Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element. Hum. Mol. Genet. 12, 2333-2340. (doi:10.1093/hmg/ddg244)
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 2333-2340
    • Olds, L.C.1    Sibley, E.2
  • 103
    • 45849145445 scopus 로고    scopus 로고
    • Identifying selected regions from heterozygosity and divergence using a light-coverage genomic dataset from two human populations
    • doi:10.1371/journal.pone. 0001712
    • Oleksyk, T. K., Zhao, K., De La Vega, F. M., Gilbert, D. A., O'Brien, S. J. & Smith, M. W. 2008 Identifying selected regions from heterozygosity and divergence using a light-coverage genomic dataset from two human populations. PLoS One 3, e1712. (doi:10.1371/journal.pone. 0001712)
    • (2008) PLoS One , vol.3
    • Oleksyk, T.K.1    Zhao, K.2    De La Vega, F.M.3    Gilbert, D.A.4    O'Brien, S.J.5    Smith, M.W.6
  • 104
    • 18444412585 scopus 로고    scopus 로고
    • A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity
    • doi: 10.1086/341290
    • Osier, M. V. et al. 2002 A global perspective on genetic variation at the ADH genes reveals unusual patterns of linkage disequilibrium and diversity. Am. J. Hum. Genet. 71, 84-99. (doi: 10.1086/341290)
    • (2002) Am. J. Hum. Genet. , vol.71 , pp. 84-99
    • Osier, M.V.1
  • 106
    • 3242878193 scopus 로고    scopus 로고
    • ECR Browser: A tool for visualizing and accessing data from comparisons of multiple vertebrate genomes
    • doi:10.1093/nar/gkh355
    • Ovcharenko, I., Nóbrega, M. A., Loots, G. G. & Stubbs, L. 2004 ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes. Nucleic Acids Res. 32, W280-W286. (doi:10.1093/nar/gkh355)
    • (2004) Nucleic Acids Res. , vol.32
    • Ovcharenko, I.1    Nóbrega, M.A.2    Loots, G.G.3    Stubbs, L.4
  • 107
    • 38449113569 scopus 로고    scopus 로고
    • Human pigmentation variation: Evolution, genetic basis, and implications for public health
    • doi:10.1002/ajpa.20727
    • Parra, E. J. 2007 Human pigmentation variation: evolution, genetic basis, and implications for public health. Am. J. Phys. Anthropol. 134, 85-105. (doi:10.1002/ajpa.20727)
    • (2007) Am. J. Phys. Anthropol. , vol.134 , pp. 85-105
    • Parra, E.J.1
  • 109
    • 36048982458 scopus 로고    scopus 로고
    • Initial sequence and comparative analysis of the cat genome
    • doi:10.1101/gr.6380007
    • Pontius, J. U. et al. 2007 Initial sequence and comparative analysis of the cat genome. Genome Res. 17, 1675-1689. (doi:10.1101/gr.6380007)
    • (2007) Genome Res. , vol.17 , pp. 1675-1689
    • Pontius, J.U.1
  • 110
    • 0344375110 scopus 로고    scopus 로고
    • The causal element for the lactase persistence/non-persistence polymorphism is located in a 1 Mb region of linkage disequilibrium in Europeans
    • doi:10.1046/j.14691809.2003.00048.x
    • Poulter, M., Hollox, E., Harvey, C. B., Mulcare, C., Peuhkuri, K., Kajander, K., Sarner, M., Korpela, R. & Swallow, D. M. 2003 The causal element for the lactase persistence/non-persistence polymorphism is located in a 1 Mb region of linkage disequilibrium in Europeans. Ann. Hum. Genet 67, 298-311. (doi:10.1046/j.14691809.2003.00048.x)
    • (2003) Ann. Hum. Genet , vol.67 , pp. 298-311
    • Poulter, M.1    Hollox, E.2    Harvey, C.B.3    Mulcare, C.4    Peuhkuri, K.5    Kajander, K.6    Sarner, M.7    Korpela, R.8    Swallow, D.M.9
  • 111
    • 34250894969 scopus 로고    scopus 로고
    • A genomewide admixture map for Latino populations
    • doi:10.1086/518313
    • Price, A. L. et al. 2007 A genomewide admixture map for Latino populations. Am. J. Hum. Genet. 80, 1024-1036. (doi:10.1086/518313)
    • (2007) Am. J. Hum. Genet. , vol.80 , pp. 1024-1036
    • Price, A.L.1
  • 112
    • 46149098096 scopus 로고    scopus 로고
    • Long-range LD can confound genome scans in admixed populations
    • doi:10.1016/j.ajhg.2008.06.005
    • Price, A. L. et al. 2008 Long-range LD can confound genome scans in admixed populations. Am. J. Hum. Genet. 83, 132-135. (doi:10.1016/j.ajhg.2008. 06.005)
    • (2008) Am. J. Hum. Genet. , vol.83 , pp. 132-135
    • Price, A.L.1
  • 113
    • 0036196885 scopus 로고    scopus 로고
    • The signature of positive selection at randomly chosen loci
    • Przeworski, M. 2002 The signature of positive selection at randomly chosen loci. Genetics 160, 1179-1189.
    • (2002) Genetics , vol.160 , pp. 1179-1189
    • Przeworski, M.1
  • 114
    • 0032918729 scopus 로고    scopus 로고
    • High polymorphism at the human melanocortin 1 receptor locus
    • Rana, B. K. et al. 1999 High polymorphism at the human melanocortin 1 receptor locus. Genetics 151, 1547-1557.
    • (1999) Genetics , vol.151 , pp. 1547-1557
    • Rana, B.K.1
  • 115
    • 0027413475 scopus 로고
    • Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function
    • doi:10.1016/00928674(93)90572-8
    • Robbins, L. S., Nadeau, J. H., Johnson, K. R., Kelly, M. A., Roselli-Rehfuss, L., Baack, E., Mountjoy, K. G. & Cone, R. D. 1993 Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function. Cell 11, 827-834. (doi:10.1016/00928674(93)90572-8)
    • (1993) Cell , vol.11 , pp. 827-834
    • Robbins, L.S.1    Nadeau, J.H.2    Johnson, K.R.3    Kelly, M.A.4    Roselli-Rehfuss, L.5    Baack, E.6    Mountjoy, K.G.7    Cone, R.D.8
  • 116
    • 0345526412 scopus 로고    scopus 로고
    • Positive selection on a human-specific transcription factor binding site regulating IL4 expression
    • doi:10. 1016/j.cub.2003.11.025
    • Rockman, M. V., Hahn, M. W., Soranzo, N., Goldstein, D. B. & Wray, G. A. 2003 Positive selection on a human-specific transcription factor binding site regulating IL4 expression. Curr. Biol. 13, 2118-2123. (doi:10. 1016/j.cub.2003.11.025)
    • (2003) Curr. Biol. , vol.13 , pp. 2118-2123
    • Rockman, M.V.1    Hahn, M.W.2    Soranzo, N.3    Goldstein, D.B.4    Wray, G.A.5
  • 117
    • 4644367204 scopus 로고    scopus 로고
    • Positive selection on MMP3 regulation has shaped heart disease risk
    • doi:10.1016/j.cub.2004.08.051
    • Rockman, M. V., Hahn, M. W., Soranzo, N., Loisel, D. A., Goldstein, D. B. & Wray, G. A. 2004 Positive selection on MMP3 regulation has shaped heart disease risk. Curr. Biol. 14, 1531-1539. (doi:10.1016/j.cub.2004.08.051)
    • (2004) Curr. Biol. , vol.14 , pp. 1531-1539
    • Rockman, M.V.1    Hahn, M.W.2    Soranzo, N.3    Loisel, D.A.4    Goldstein, D.B.5    Wray, G.A.6
  • 118
    • 4544360647 scopus 로고    scopus 로고
    • Genetic variation at the MC IR locus and the time since loss of human body hair
    • doi: 10.1086/ 381006
    • Rogers, A. R., Iltis, D. & Wooding, S. 2004 Genetic variation at the MC IR locus and the time since loss of human body hair. Curr. Anthropol. 45, 105-108. (doi: 10.1086/ 381006)
    • (2004) Curr. Anthropol. , vol.45 , pp. 105-108
    • Rogers, A.R.1    Iltis, D.2    Wooding, S.3
  • 119
    • 0037167852 scopus 로고    scopus 로고
    • Detecting recent positive selection in the human genome from haplotype structure
    • doi:10.1038/nature01140
    • Sabeti, P. C. et al. 2002 Detecting recent positive selection in the human genome from haplotype structure. Nature 419, 832-837. (doi:10.1038/ nature01140)
    • (2002) Nature , vol.419 , pp. 832-837
    • Sabeti, P.C.1
  • 120
    • 27844526221 scopus 로고    scopus 로고
    • The case for selection at CCR5Delta32
    • doi:10.1371/journal.pbio. 0030378
    • Sabeti, P. C. et al. 2005 The case for selection at CCR5Delta32. PLoS Biol. 3, e378. (doi:10.1371/journal.pbio. 0030378)
    • (2005) PLoS Biol. , vol.3
    • Sabeti, P.C.1
  • 121
    • 33745121154 scopus 로고    scopus 로고
    • Positive natural selection in the human lineage
    • doi:10.1126/ science. 1124309
    • Sabeti, P. C. et al. 2006 Positive natural selection in the human lineage. Science 312, 1614-1620. (doi:10.1126/ science. 1124309)
    • (2006) Science , vol.312 , pp. 1614-1620
    • Sabeti, P.C.1
  • 122
    • 35349012592 scopus 로고    scopus 로고
    • Genome-wide detection and characterization of positive selection in human populations
    • doi:10.1038/nature06250
    • Sabeti, P. C. et al. 2007 Genome-wide detection and characterization of positive selection in human populations. Nature 449, 913-918. (doi:10.1038/nature06250)
    • (2007) Nature , vol.449 , pp. 913-918
    • Sabeti, P.C.1
  • 123
    • 4344661241 scopus 로고    scopus 로고
    • Local adaptation and population differentiation at the interleukin 13 and interleukin 4 loci
    • doi:10.1038/sj.gene. 6364109
    • Sakagami, T. et al. 2004 Local adaptation and population differentiation at the interleukin 13 and interleukin 4 loci. Genes Immun. 5, 389-397. (doi:10.1038/sj.gene. 6364109)
    • (2004) Genes Immun. , vol.5 , pp. 389-397
    • Sakagami, T.1
  • 124
    • 0036963687 scopus 로고    scopus 로고
    • Nucleotide variability at G6pd and the signature of malarial selection in humans
    • Saunders, M. A., Hammer, M. F. & Nachman, M. W. 2002 Nucleotide variability at G6pd and the signature of malarial selection in humans. Genetics 162, 1849-1861.
    • (2002) Genetics , vol.162 , pp. 1849-1861
    • Saunders, M.A.1    Hammer, M.F.2    Nachman, M.W.3
  • 125
    • 42549162952 scopus 로고    scopus 로고
    • Nucleotide diversity and population differentiation of the Melanocortin 1 Receptor gene
    • doi: 10. 1186/1471-2156-9-31
    • Savage, S., Gerstenblith, M., Goldstein, A., Mirabello, L., Fargnoli, M., Peris, K. & Landi, M. 2008 Nucleotide diversity and population differentiation of the Melanocortin 1 Receptor gene, MC1R. BMC Genet. 9, 31. (doi: 10. 1186/1471-2156-9-31)
    • (2008) MC1R. BMC Genet. , vol.9 , pp. 31
    • Savage, S.1    Gerstenblith, M.2    Goldstein, A.3    Mirabello, L.4    Fargnoli, M.5    Peris, K.6    Landi, M.7
  • 126
    • 14544281087 scopus 로고    scopus 로고
    • Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain
    • doi: 10. 1073/pnas.0409853102
    • Sawyer, S. L., Wu, L. I., Emerman, M. & Malik, H. S. 2005 Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain. Proc. Natl Acad. Sci. USA 102, 2832-2837. (doi: 10. 1073/pnas.0409853102)
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 2832-2837
    • Sawyer, S.L.1    Wu, L.I.2    Emerman, M.3    Malik, H.S.4
  • 127
    • 0036792107 scopus 로고    scopus 로고
    • Microsatellite variation and evolution of the human Duffy blood group polymorphism
    • Seixas, S., Ferrand, N. & Rocha, J. 2002 Microsatellite variation and evolution of the human Duffy blood group polymorphism. Mol. Biol. Evol. 19, 1802-1806.
    • (2002) Mol. Biol. Evol. , vol.19 , pp. 1802-1806
    • Seixas, S.1    Ferrand, N.2    Rocha, J.3
  • 128
    • 0141923845 scopus 로고    scopus 로고
    • The nature of diversity and diversification at the ABO locus
    • doi:10.1182/blood-2003-03-0955
    • Seltsam, A., Hallensleben, M., Kollmann, A. & Blasczyk, R. 2003 The nature of diversity and diversification at the ABO locus. Blood 102, 3035-3042. (doi:10.1182/blood-2003-03-0955)
    • (2003) Blood , vol.102 , pp. 3035-3042
    • Seltsam, A.1    Hallensleben, M.2    Kollmann, A.3    Blasczyk, R.4
  • 129
    • 0034884532 scopus 로고    scopus 로고
    • Simulating genealogies of selected alleles in a population of variable size
    • Slatkin, M. 2001 Simulating genealogies of selected alleles in a population of variable size. Genet. Res. 78, 49-57.
    • (2001) Genet. Res. , vol.78 , pp. 49-57
    • Slatkin, M.1
  • 130
    • 22944467804 scopus 로고    scopus 로고
    • Mapping by admixture linkage disequilibrium: Advances, limitations and guidelines
    • doi:10.1038/nrg1657
    • Smith, M. W. & O'Brien, S. J. 2005 Mapping by admixture linkage disequilibrium: advances, limitations and guidelines. Nat. Rev. Genet. 6, 623-632. (doi:10.1038/nrg1657)
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 623-632
    • Smith, M.W.1    O'Brien, S.J.2
  • 131
    • 7144254441 scopus 로고    scopus 로고
    • Melanocortin 1 receptor variants in an Irish population
    • doi:10.1046/j.1523-1747.1998.00252.x
    • Smith, R. et al. 1998 Melanocortin 1 receptor variants in an Irish population. J. Invest. Dermatol. 111, 119-122. (doi:10.1046/j.1523-1747.1998. 00252.x)
    • (1998) J. Invest. Dermatol. , vol.111 , pp. 119-122
    • Smith, R.1
  • 132
    • 2342597140 scopus 로고    scopus 로고
    • A high-density admixture map for disease gene discovery in African Americans
    • doi: 10.1086/420856
    • Smith, M. W et al. 2004 A high-density admixture map for disease gene discovery in African Americans. Am. J. Hum. Genet. 74, 1001-1013. (doi: 10.1086/420856)
    • (2004) Am. J. Hum. Genet. , vol.74 , pp. 1001-1013
    • Smith, M.W.1
  • 133
    • 10344221021 scopus 로고    scopus 로고
    • Disentangling the effects of demography and selection in human history
    • doi:10.1093/molbev/msh252
    • Stajich, J. E. & Hahn, M. W. 2005 Disentangling the effects of demography and selection in human history. Mol. Biol. Evol. 11, 63-73. (doi:10.1093/molbev/msh252)
    • (2005) Mol. Biol. Evol. , vol.11 , pp. 63-73
    • Stajich, J.E.1    Hahn, M.W.2
  • 134
    • 17344372255 scopus 로고    scopus 로고
    • Dating the origin of the CCR5Delta32 AIDS-resistance allele by the coalescence of haplotypes
    • doi: 10.1086/301867
    • Stephens, J. C. et al. 1998 Dating the origin of the CCR5Delta32 AIDS-resistance allele by the coalescence of haplotypes. Am. J. Hum. Genet. 62, 1507-1515. (doi: 10.1086/301867)
    • (1998) Am. J. Hum. Genet. , vol.62 , pp. 1507-1515
    • Stephens, J.C.1
  • 135
    • 36549071998 scopus 로고    scopus 로고
    • Genetic determinants of hair, eye and skin pigmentation in Europeans
    • doi:10.1038/ng.2007.13
    • Sulem, P. et al. 2007 Genetic determinants of hair, eye and skin pigmentation in Europeans. Nat. Genet. 39, 1443-1452. (doi:10.1038/ng.2007.13)
    • (2007) Nat. Genet. , vol.39 , pp. 1443-1452
    • Sulem, P.1
  • 136
    • 0024313579 scopus 로고
    • Statistical method for testing the neutral mutation hypothesis by DNA polymorphism
    • Tajima, F. 1989 Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123, 585-595.
    • (1989) Genetics , vol.123 , pp. 585-595
    • Tajima, F.1
  • 137
    • 0027453388 scopus 로고
    • Simple methods for testing molecular clock hypothesis
    • Tajima, F. 1993 Simple methods for testing molecular clock hypothesis. Genetics 135, 599-607.
    • (1993) Genetics , vol.135 , pp. 599-607
    • Tajima, F.1
  • 138
    • 0032898736 scopus 로고    scopus 로고
    • Molecular analysis of a new splice variant of the human melanocortin-1 receptor
    • doi:10.1016/S0014-5793(99)00525-6
    • Tan, C. P. et al. 1999 Molecular analysis of a new splice variant of the human melanocortin-1 receptor. FEBS Lett. 451, 137-141. (doi:10.1016/S0014- 5793(99)00525-6)
    • (1999) FEBS Lett. , vol.451 , pp. 137-141
    • Tan, C.P.1
  • 142
    • 33645058439 scopus 로고    scopus 로고
    • Sequence diversity and haplotype structure at the human CYP3A cluster
    • doi:10.1038/sj.tpj.6500347
    • Thompson, E. E., Kuttab-Boulos, H., Yang, L., Roe, B. A. & Di Rienzo, A. 2006 Sequence diversity and haplotype structure at the human CYP3A cluster. Pharmacogenomics J. 6, 105-114. (doi:10.1038/sj.tpj.6500347)
    • (2006) Pharmacogenomics J. , vol.6 , pp. 105-114
    • Thompson, E.E.1    Kuttab-Boulos, H.2    Yang, L.3    Roe, B.A.4    Di Rienzo, A.5
  • 143
    • 0035919696 scopus 로고    scopus 로고
    • Haplotype diversity and linkage disequilibrium at human G6PD: Recent origin of alleles that confer malarial resistance
    • doi:10.1126/science.1061573
    • Tishkoff, S. A. et al. 2001 Haplotype diversity and linkage disequilibrium at human G6PD: recent origin of alleles that confer malarial resistance. Science 293, 455-462. (doi:10.1126/science.1061573)
    • (2001) Science , vol.293 , pp. 455-462
    • Tishkoff, S.A.1
  • 144
    • 33845900450 scopus 로고    scopus 로고
    • Convergent adaptation of human lactase persistence in Africa and Europe
    • doi:10.1038/ng1946
    • Tishkoff, S. A. et al. 2007 Convergent adaptation of human lactase persistence in Africa and Europe. Nat. Genet. 39, 31-40. (doi:10.1038/ng1946)
    • (2007) Nat. Genet. , vol.39 , pp. 31-40
    • Tishkoff, S.A.1
  • 145
    • 0036671928 scopus 로고    scopus 로고
    • Sequence variation and haplotype structure at the human HFE locus
    • Toomajian, C. & Kreitman, M. 2002 Sequence variation and haplotype structure at the human HFE locus. Genetics 161, 1609-1623.
    • (2002) Genetics , vol.161 , pp. 1609-1623
    • Toomajian, C.1    Kreitman, M.2
  • 146
    • 0029001881 scopus 로고
    • Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffynegative individuals
    • doi: 10. 1038/ng0695-224
    • Tournamille, C., Colin, Y., Cartron, J. P. & Le Van Kim, C. 1995 Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffynegative individuals. Nat. Genet. 10, 224-228. (doi: 10. 1038/ng0695-224)
    • (1995) Nat. Genet. , vol.10 , pp. 224-228
    • Tournamille, C.1    Colin, Y.2    Cartron, J.P.3    Van Le Kim, C.4
  • 147
    • 0345059399 scopus 로고    scopus 로고
    • An upstream polymorphism associated with lactase persistence has increased enhancer activity
    • doi:10.1053/j.gastro.2003.09.031
    • Troelsen, J. T., Olsen, J., Moller, J. & Sjostrom, H. 2003 An upstream polymorphism associated with lactase persistence has increased enhancer activity. Gastroenterology 125, 1686-1694. (doi:10.1053/j.gastro.2003.09.031)
    • (2003) Gastroenterology , vol.125 , pp. 1686-1694
    • Troelsen, J.T.1    Olsen, J.2    Moller, J.3    Sjostrom, H.4
  • 148
    • 33748061950 scopus 로고    scopus 로고
    • Contrasting histories of G6PD molecular evolution and malarial resistance in humans and chimpanzees
    • doi:10.1093/ molbev/ms1024
    • Verrelli, B. C., Tishkoff, S. A., Stone, A. C. & Touchman, J. W. 2006 Contrasting histories of G6PD molecular evolution and malarial resistance in humans and chimpanzees. Mol. Biol. Evol. 23, 1592-1601. (doi:10.1093/ molbev/ms1024)
    • (2006) Mol. Biol. Evol. , vol.23 , pp. 1592-1601
    • Verrelli, B.C.1    Tishkoff, S.A.2    Stone, A.C.3    Touchman, J.W.4
  • 149
    • 33644981509 scopus 로고    scopus 로고
    • A map of recent positive selection in the human genome
    • doi:10.1371/journal.pbio. 0040072
    • Voight, B. F., Kudaravalli, S., Wen, X. & Pritchard, J. K. 2006 A map of recent positive selection in the human genome. PLoS Biol. 4, e72. (doi:10.1371/journal.pbio. 0040072)
    • (2006) PLoS Biol. , vol.4
    • Voight, B.F.1    Kudaravalli, S.2    Wen, X.3    Pritchard, J.K.4
  • 150
    • 0033580401 scopus 로고    scopus 로고
    • The limits of selection during maize domestication
    • Wang, R. L., Stec, A., Hey, J., Lukens, L. & Doebley, J. 1999 The limits of selection during maize domestication. Nature 398, 236-239.
    • (1999) Nature , vol.398 , pp. 236-239
    • Wang, R.L.1    Stec, A.2    Hey, J.3    Lukens, L.4    Doebley, J.5
  • 151
    • 2342531738 scopus 로고    scopus 로고
    • The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus
    • doi:10.1086/420854
    • Wang, E. et al. 2004 The genetic architecture of selection at the human dopamine receptor D4 (DRD4) gene locus. Am. J. Hum. Genet. 74, 931-944. (doi:10.1086/420854)
    • (2004) Am. J. Hum. Genet. , vol.74 , pp. 931-944
    • Wang, E.1
  • 152
    • 30444460720 scopus 로고    scopus 로고
    • Global landscape of recent inferred Darwinian selection for Homo sapiens
    • doi:10.1073/pnas.0509691102
    • Wang, E. T., Kodama, G., Baldi, P. & Moyzis, R. K. 2006 Global landscape of recent inferred Darwinian selection for Homo sapiens. Proc. Natl Acad. Sci. USA 103, 135-140. (doi:10.1073/pnas.0509691102)
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 135-140
    • Wang, E.T.1    Kodama, G.2    Baldi, P.3    Moyzis, R.K.4
  • 153
    • 84890417804 scopus 로고
    • The genetical structure of populations
    • Wright, S. 1951 The genetical structure of populations. Ann. Eugenics 15, 323-354.
    • (1951) Ann. Eugenics , vol.15 , pp. 323-354
    • Wright, S.1
  • 154
    • 33645462359 scopus 로고    scopus 로고
    • Spread of an inactive form of caspase-12 in humans is due to recent positive selection
    • doi:10.1086/503116
    • Xue, Y. et al. 2006 Spread of an inactive form of caspase-12 in humans is due to recent positive selection. Am. J. Hum. Genet. 78, 659-670. (doi:10.1086/503116)
    • (2006) Am. J. Hum. Genet. , vol.78 , pp. 659-670
    • Xue, Y.1
  • 155
    • 0031960185 scopus 로고    scopus 로고
    • Synonymous and nonsynonymous rate variation in nuclear genes of mammals
    • doi:10.1007/PL00006320
    • Yang, Z. & Nielsen, R. 1998 Synonymous and nonsynonymous rate variation in nuclear genes of mammals. J. Mol. Evol. 46, 409-418. (doi:10.1007/PL00006320)
    • (1998) J. Mol. Evol. , vol.46 , pp. 409-418
    • Yang, Z.1    Nielsen, R.2
  • 156
    • 0042561796 scopus 로고    scopus 로고
    • Of mice and men: Phylogenetic footprinting aids the discovery of regulatory elements
    • doi:10.1186/1475-4924-2-11
    • Zhang, Z. & Gerstein, M. 2003 Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements. J. Biol. 1, 11. (doi:10.1186/1475-4924-2-11)
    • (2003) J. Biol. , vol.1 , pp. 11
    • Zhang, Z.1    Gerstein, M.2


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