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Volumn 1 S, Issue 1, 2009, Pages 132-141

CTGF and chronic kidney fibrosis

Author keywords

CTGF; Diabetic nephropathy; Epithelial to mesenchymal transition; Renal fibrosis; Review; Tubulointerstitial fibrosis

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; CTGF PROTEIN, HUMAN;

EID: 75449084561     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: 10.2741/e13     Document Type: Review
Times cited : (55)

References (94)
  • 1
    • 0036786834 scopus 로고    scopus 로고
    • TGF-beta signaling in renal disease
    • E. P. Bottinger and M. Bitzer: TGF-beta signaling in renal disease. J Am Soc Nephrol 13, 2600-2600 (2002)
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2600-2600
    • Bottinger, E.P.1    Bitzer, M.2
  • 2
    • 15844402989 scopus 로고    scopus 로고
    • Combining TGF-beta inhibition and angiotensin II blockade results in enhanced antifibrotic effect
    • L. Yu, W. A. Border, I. Anderson, M. McCourt, Y. Huang and N. A. Noble: Combining TGF-beta inhibition and angiotensin II blockade results in enhanced antifibrotic effect. Kidney Int 66, 1774-1774 (2004)
    • (2004) Kidney Int , vol.66 , pp. 1774-1774
    • Yu, L.1    Border, W.A.2    Anderson, I.3    McCourt, M.4    Huang, Y.5    Noble, N.A.6
  • 3
    • 28544448737 scopus 로고    scopus 로고
    • Reactive oxygen species amplify glucose signalling in renal cells cultured under high glucose and in diabetic kidney
    • DOI 10.1111/j.1440-1797.2005.00448.x
    • H. Ha and H. B. Lee: Reactive oxygen species amplify glucose signalling in renal cells cultured under high glucose and in diabetic kidney. Nephrology (Carlton) 10 Suppl, S7-10 (2005) (Pubitemid 41743468)
    • (2005) Nephrology , vol.10 , Issue.SUPPL. 2
    • Ha, H.1    Lee, H.B.2
  • 4
    • 34548824337 scopus 로고    scopus 로고
    • High glucoseinduced thioredoxin-interacting protein in renal proximal tubule cells is independent of transforming growth factorbeta1
    • W. Qi, X. Chen, R. E. Gilbert, Y. Zhang, M. Waltham, M. Schache, D. J. Kelly and C. A. Pollock: High glucoseinduced thioredoxin-interacting protein in renal proximal tubule cells is independent of transforming growth factorbeta1. Am J Pathol 171, 744-744 (2007)
    • (2007) Am J Pathol , vol.171 , pp. 744-744
    • Qi, W.1    Chen, X.2    Gilbert, R.E.3    Zhang, Y.4    Waltham, M.5    Schache, M.6    Kelly, D.J.7    Pollock, C.A.8
  • 5
    • 33644638349 scopus 로고    scopus 로고
    • Renal fibrosis: New insights into the pathogenesis and therapeutics
    • Y. Liu: Renal fibrosis: new insights into the pathogenesis and therapeutics. Kidney Int 69, 213-213 (2006)
    • (2006) Kidney Int , vol.69 , pp. 213-213
    • Liu, Y.1
  • 7
    • 9444248661 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF)/CCN2 stimulates mesangial cell migration through integrated dissolution of focal adhesion complexes and activation of cell polarization
    • J. K. Crean, F. Furlong, D. Finlay, D. Mitchell, M. Murphy, B. Conway, H. R. Brady, C. Godson and F. Martin: Connective tissue growth factor (CTGF)/CCN2 stimulates mesangial cell migration through integrated dissolution of focal adhesion complexes and activation of cell polarization. Faseb J 18, 1541-1541 (2004)
    • (2004) Faseb J , vol.18 , pp. 1541-1541
    • Crean, J.K.1    Furlong, F.2    Finlay, D.3    Mitchell, D.4    Murphy, M.5    Conway, B.6    Brady, H.R.7    Godson, C.8    Martin, F.9
  • 8
    • 0030707954 scopus 로고    scopus 로고
    • Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): Characterization of connective tissue growth factor as a member of the IGFBP superfamily
    • H. S. Kim, S. R. Nagalla, Y. Oh, E. Wilson, C. T. Roberts, Jr. and R. G. Rosenfeld: Identification of a family of low-affinity insulin-like growth factor binding proteins (IGFBPs): characterization of connective tissue growth factor as a member of the IGFBP superfamily. Proc Natl Acad Sci U S A 94, 12981-12981 (1997)
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 12981-12981
    • Kim, H.S.1    Nagalla, S.R.2    Oh, Y.3    Wilson, E.4    Roberts Jr., C.T.5    Rosenfeld, R.G.6
  • 9
    • 0032580269 scopus 로고    scopus 로고
    • How many insulin-like growth factor binding proteins?
    • C. Collet and J. Candy: How many insulin-like growth factor binding proteins? Mol Cell Endocrinol 139, 1-1 (1998)
    • (1998) Mol Cell Endocrinol , vol.139 , pp. 1-1
    • Collet, C.1    Candy, J.2
  • 10
    • 0031786081 scopus 로고    scopus 로고
    • Identification of glycosylated 38-kDa connective tissue growth factor (IGFBP-related protein 2) and proteolytic fragments in human biological fluids, and up-regulation of IGFBP-rP2 expression by TGF-beta in Hs578T human breast cancer cells
    • D. H. Yang, H. S. Kim, E. M. Wilson, R. G. Rosenfeld and Y. Oh: Identification of glycosylated 38-kDa connective tissue growth factor (IGFBP-related protein 2) and proteolytic fragments in human biological fluids, and up-regulation of IGFBP-rP2 expression by TGF-beta in Hs578T human breast cancer cells. J Clin Endocrinol Metab 83, 2593-2593 (1998)
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2593-2593
    • Yang, D.H.1    Kim, H.S.2    Wilson, E.M.3    Rosenfeld, R.G.4    Oh, Y.5
  • 11
    • 0031976881 scopus 로고    scopus 로고
    • Characterization of cell-associated and soluble forms of connective tissue growth factor (CTGF) produced by fibroblast cells in vitro
    • C. L. Steffen, D. K. Ball-Mirth, P. A. Harding, N. Bhattacharyya, S. Pillai and D. R. Brigstock: Characterization of cell-associated and soluble forms of connective tissue growth factor (CTGF) produced by fibroblast cells in vitro. Growth Factors 15, 199-199 (1998)
    • (1998) Growth Factors , vol.15 , pp. 199-199
    • Steffen, C.L.1    Ball-Mirth, D.K.2    Harding, P.A.3    Bhattacharyya, N.4    Pillai, S.5    Brigstock, D.R.6
  • 12
    • 0030754093 scopus 로고    scopus 로고
    • Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids. Identification as heparin-regulated Mr 10, 000 forms of connective tissue growth factor
    • D. R. Brigstock, C. L. Steffen, G. Y. Kim, R. K. Vegunta, J. R. Diehl and P. A. Harding: Purification and characterization of novel heparin-binding growth factors in uterine secretory fluids. Identification as heparin-regulated Mr 10, 000 forms of connective tissue growth factor. J Biol Chem 272, 20275-20275 (1997)
    • (1997) J Biol Chem , vol.272 , pp. 20275-20275
    • Brigstock, D.R.1    Steffen, C.L.2    Kim, G.Y.3    Vegunta, R.K.4    Diehl, J.R.5    Harding, P.A.6
  • 13
    • 0033957976 scopus 로고    scopus 로고
    • Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis
    • B. L. Riser, M. Denichilo, P. Cortes, C. Baker, J. M. Grondin, J. Yee and R. G. Narins: Regulation of connective tissue growth factor activity in cultured rat mesangial cells and its expression in experimental diabetic glomerulosclerosis. J Am Soc Nephrol 11, 25-25 (2000)
    • (2000) J Am Soc Nephrol , vol.11 , pp. 25-25
    • Riser, B.L.1    Denichilo, M.2    Cortes, P.3    Baker, C.4    Grondin, J.M.5    Yee, J.6    Narins, R.G.7
  • 14
    • 0026055366 scopus 로고
    • Connective tissue growth factor: A cysteinerich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
    • D. M. Bradham, A. Igarashi, R. L. Potter and G. R. Grotendorst: Connective tissue growth factor: a cysteinerich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J Cell Biol 114, 1285-1285 (1991)
    • (1991) J Cell Biol , vol.114 , pp. 1285-1285
    • Bradham, D.M.1    Igarashi, A.2    Potter, R.L.3    Grotendorst, G.R.4
  • 15
    • 0034972945 scopus 로고    scopus 로고
    • Identification of human ccn2 (connective tissue growth factor) promoter polymorphisms
    • I. E. Blom, A. J. van Dijk, R. A. de Weger, M. G. Tilanus and R. Goldschmeding: Identification of human ccn2 (connective tissue growth factor) promoter polymorphisms. Mol Pathol 54, 192-192 (2001)
    • (2001) Mol Pathol , vol.54 , pp. 192-192
    • Blom, I.E.1    Van Dijk, A.J.2    De Weger, R.A.3    Tilanus, M.G.4    Goldschmeding, R.5
  • 19
    • 0031586015 scopus 로고    scopus 로고
    • Cyr61 and Fisp12 are both ECM-associated signaling molecules: Activities, metabolism, and localization during development
    • M. L. Kireeva, B. V. Latinkic, T. V. Kolesnikova, C. C. Chen, G. P. Yang, A. S. Abler and L. F. Lau: Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development. Exp Cell Res 233, 63-63 (1997)
    • (1997) Exp Cell Res , vol.233 , pp. 63-63
    • Kireeva, M.L.1    Latinkic, B.V.2    Kolesnikova, T.V.3    Chen, C.C.4    Yang, G.P.5    Abler, A.S.6    Lau, L.F.7
  • 20
    • 0030907579 scopus 로고    scopus 로고
    • Cloning of a mRNA preferentially expressed in chondrocytes by differential display-PCR from a human chondrocytic cell line that is identical with connective tissue growth factor (CTGF) mRNA
    • T. Nakanishi, Y. Kimura, T. Tamura, H. Ichikawa, Y. Yamaai, T. Sugimoto and M. Takigawa: Cloning of a mRNA preferentially expressed in chondrocytes by differential display-PCR from a human chondrocytic cell line that is identical with connective tissue growth factor (CTGF) mRNA. Biochem Biophys Res Commun 234, 206-206 (1997)
    • (1997) Biochem Biophys Res Commun , vol.234 , pp. 206-206
    • Nakanishi, T.1    Kimura, Y.2    Tamura, T.3    Ichikawa, H.4    Yamaai, Y.5    Sugimoto, T.6    Takigawa, M.7
  • 21
    • 0029816069 scopus 로고    scopus 로고
    • Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor
    • K. Frazier, S. Williams, D. Kothapalli, H. Klapper and G. R. Grotendorst: Stimulation of fibroblast cell growth, matrix production, and granulation tissue formation by connective tissue growth factor. J Invest Dermatol 107, 404-404 (1996)
    • (1996) J Invest Dermatol , vol.107 , pp. 404-404
    • Frazier, K.1    Williams, S.2    Kothapalli, D.3    Klapper, H.4    Grotendorst, G.R.5
  • 22
    • 0033541389 scopus 로고    scopus 로고
    • The CCN family of angiogenic regulators: The integrin connection
    • L. F. Lau and S. C. Lam: The CCN family of angiogenic regulators: the integrin connection. Exp Cell Res 248, 44-44 (1999)
    • (1999) Exp Cell Res , vol.248 , pp. 44-44
    • Lau, L.F.1    Lam, S.C.2
  • 24
    • 37549068908 scopus 로고    scopus 로고
    • Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: Disruption of vascular endothelial growth factor (VEGF)/heparin affin regulatory peptide (pleiotrophin) and VEGF/Connective tissue growth factor angiogenic inhibitory complexes by MMP-2 proteolysis
    • R. A. Dean, G. S. Butler, Y. Hamma-Kourbali, J. Delbe, D. R. Brigstock, J. Courty and C. M. Overall: Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth factor (VEGF)/heparin affin regulatory peptide (pleiotrophin) and VEGF/Connective tissue growth factor angiogenic inhibitory complexes by MMP-2 proteolysis. Mol Cell Biol 27, 8454-8454 (2007)
    • (2007) Mol Cell Biol , vol.27 , pp. 8454-8454
    • Dean, R.A.1    Butler, G.S.2    Hamma-Kourbali, Y.3    Delbe, J.4    Brigstock, D.R.5    Courty, J.6    Overall, C.M.7
  • 25
    • 0037840309 scopus 로고    scopus 로고
    • Regulation of angiogenesis and endothelial cell function by connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61)
    • D. R. Brigstock: Regulation of angiogenesis and endothelial cell function by connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61) Angiogenesis 5, 153-153 (2002)
    • (2002) Angiogenesis , vol.5 , pp. 153-153
    • Brigstock, D.R.1
  • 30
    • 0027229995 scopus 로고
    • Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair
    • A. Igarashi, H. Okochi, D. M. Bradham and G. R. Grotendorst: Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol Biol Cell 4, 637-637 (1993)
    • (1993) Mol Biol Cell , vol.4 , pp. 637-637
    • Igarashi, A.1    Okochi, H.2    Bradham, D.M.3    Grotendorst, G.R.4
  • 31
    • 0036051343 scopus 로고    scopus 로고
    • Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta
    • J. G. Abreu, N. I. Ketpura, B. Reversade and E. M. De Robertis: Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta. Nat Cell Biol 4, 599-599 (2002)
    • (2002) Nat Cell Biol , vol.4 , pp. 599-599
    • Abreu, J.G.1    Ketpura, N.I.2    Reversade, B.3    De Robertis, E.M.4
  • 32
    • 0029808645 scopus 로고    scopus 로고
    • A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene
    • G. R. Grotendorst, H. Okochi and N. Hayashi: A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene. Cell Growth Differ 7, 469-469 (1996)
    • (1996) Cell Growth Differ , vol.7 , pp. 469-469
    • Grotendorst, G.R.1    Okochi, H.2    Hayashi, N.3
  • 33
    • 0034971702 scopus 로고    scopus 로고
    • The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblasts
    • A. Leask, S. Sa, A. Holmes, X. Shiwen, C. M. Black and D. J. Abraham: The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblasts. Mol Pathol 54, 180-180 (2001)
    • (2001) Mol Pathol , vol.54 , pp. 180-180
    • Leask, A.1    Sa, S.2    Holmes, A.3    Shiwen, X.4    Black, C.M.5    Abraham, D.J.6
  • 34
    • 0038644847 scopus 로고    scopus 로고
    • Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts
    • A. Leask, A. Holmes, C. M. Black and D. J. Abraham: Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts. J Biol Chem 278, 13008-13008 (2003)
    • (2003) J Biol Chem , vol.278 , pp. 13008-13008
    • Leask, A.1    Holmes, A.2    Black, C.M.3    Abraham, D.J.4
  • 35
    • 0035815683 scopus 로고    scopus 로고
    • CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling
    • A. Holmes, D. J. Abraham, S. Sa, X. Shiwen, C. M. Black and A. Leask: CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling. J Biol Chem 276, 10594-10594 (2001)
    • (2001) J Biol Chem , vol.276 , pp. 10594-10594
    • Holmes, A.1    Abraham, D.J.2    Sa, S.3    Shiwen, X.4    Black, C.M.5    Leask, A.6
  • 36
    • 0036378148 scopus 로고    scopus 로고
    • CTGF expression in mesangial cells: Involvement of SMADs, MAP kinase, and PKC
    • Y. Chen, I. E. Blom, S. Sa, R. Goldschmeding, D. J. Abraham and A. Leask: CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC. Kidney Int 62, 1149-1149 (2002)
    • (2002) Kidney Int , vol.62 , pp. 1149-1149
    • Chen, Y.1    Blom, I.E.2    Sa, S.3    Goldschmeding, R.4    Abraham, D.J.5    Leask, A.6
  • 37
    • 20444399088 scopus 로고    scopus 로고
    • Modulation of the TGFbeta/Smad signaling pathway in mesangial cells by CTGF/CCN2
    • N. A. Wahab, B. S. Weston and R. M. Mason: Modulation of the TGFbeta/Smad signaling pathway in mesangial cells by CTGF/CCN2. Exp Cell Res 307, 305-305 (2005)
    • (2005) Exp Cell Res , vol.307 , pp. 305-305
    • Wahab, N.A.1    Weston, B.S.2    Mason, R.M.3
  • 38
    • 30744478450 scopus 로고    scopus 로고
    • The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFbeta1 responses in human proximal-tubule epithelial cells
    • M. K. Phanish, N. A. Wahab, P. Colville-Nash, B. M. Hendry and M. E. Dockrell: The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFbeta1 responses in human proximal-tubule epithelial cells. Biochem J 393, 601-601 (2006)
    • (2006) Biochem J , vol.393 , pp. 601-601
    • Phanish, M.K.1    Wahab, N.A.2    Colville-Nash, P.3    Hendry, B.M.4    Dockrell, M.E.5
  • 39
    • 0036775477 scopus 로고    scopus 로고
    • Gene regulation of connective tissue growth factor: New targets for antifibrotic therapy?
    • I. E. Blom, R. Goldschmeding and A. Leask: Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy? Matrix Biol 21, 473-473 (2002)
    • (2002) Matrix Biol , vol.21 , pp. 473-473
    • Blom, I.E.1    Goldschmeding, R.2    Leask, A.3
  • 40
    • 0035991406 scopus 로고    scopus 로고
    • Nitric oxide down-regulates connective tissue growth factor in rat mesangial cells
    • A. Keil, I. E. Blom, R. Goldschmeding and H. D. Rupprecht: Nitric oxide down-regulates connective tissue growth factor in rat mesangial cells. Kidney Int 62, 401-401 (2002)
    • (2002) Kidney Int , vol.62 , pp. 401-401
    • Keil, A.1    Blom, I.E.2    Goldschmeding, R.3    Rupprecht, H.D.4
  • 41
    • 20444384532 scopus 로고    scopus 로고
    • Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA
    • N. A. Wahab, B. S. Weston and R. M. Mason: Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA. J Am Soc Nephrol 16, 340-340 (2005)
    • (2005) J Am Soc Nephrol , vol.16 , pp. 340-340
    • Wahab, N.A.1    Weston, B.S.2    Mason, R.M.3
  • 42
    • 34248203088 scopus 로고    scopus 로고
    • The differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1
    • W. Qi, X. Chen, S. Twigg, Y. Zhang, R. E. Gilbert, D. J. Kelly and C. A. Pollock: The differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1. Nephrology (Carlton) 12, 267-267 (2007)
    • (2007) Nephrology (Carlton) , vol.12 , pp. 267-267
    • Qi, W.1    Chen, X.2    Twigg, S.3    Zhang, Y.4    Gilbert, R.E.5    Kelly, D.J.6    Pollock, C.A.7
  • 46
    • 0033623771 scopus 로고    scopus 로고
    • Effects of CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro
    • T. Nishida, T. Nakanishi, M. Asano, T. Shimo and M. Takigawa: Effects of CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro. J Cell Physiol 184, 197-197 (2000)
    • (2000) J Cell Physiol , vol.184 , pp. 197-197
    • Nishida, T.1    Nakanishi, T.2    Asano, M.3    Shimo, T.4    Takigawa, M.5
  • 47
    • 0242690484 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein (LRP) is a heparin-dependent adhesion receptor for connective tissue growth factor (CTGF) in rat activated hepatic stellate cells
    • R. Gao and D. R. Brigstock: Low density lipoprotein receptor-related protein (LRP) is a heparin-dependent adhesion receptor for connective tissue growth factor (CTGF) in rat activated hepatic stellate cells. Hepatol Res 27, 214-214 (2003)
    • (2003) Hepatol Res , vol.27 , pp. 214-214
    • Gao, R.1    Brigstock, D.R.2
  • 48
    • 0035890235 scopus 로고    scopus 로고
    • Connective tissue growth factor is secreted through the Golgi and is degraded in the endosome
    • Y. Chen, P. Segarini, F. Raoufi, D. Bradham and A. Leask: Connective tissue growth factor is secreted through the Golgi and is degraded in the endosome. Exp Cell Res 271, 109-109 (2001)
    • (2001) Exp Cell Res , vol.271 , pp. 109-109
    • Chen, Y.1    Segarini, P.2    Raoufi, F.3    Bradham, D.4    Leask, A.5
  • 49
    • 10044274113 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the LDL receptor-related protein (LRP) and activation of the ERK pathway are required for connective tissue growth factor to potentiate myofibroblast differentiation
    • M. Yang, H. Huang, J. Li, D. Li and H. Wang: Tyrosine phosphorylation of the LDL receptor-related protein (LRP) and activation of the ERK pathway are required for connective tissue growth factor to potentiate myofibroblast differentiation. Faseb J 18, 1920-1920 (2004)
    • (2004) Faseb J , vol.18 , pp. 1920-1920
    • Yang, M.1    Huang, H.2    Li, J.3    Li, D.4    Wang, H.5
  • 51
    • 34250733867 scopus 로고    scopus 로고
    • The role of tubular epithelial-mesenchymal transition in progressive kidney disease
    • W. C. Burns, P. Kantharidis and M. C. Thomas: The role of tubular epithelial-mesenchymal transition in progressive kidney disease. Cells Tissues Organs 185, 222-222 (2007)
    • (2007) Cells Tissues Organs , vol.185 , pp. 222-222
    • Burns, W.C.1    Kantharidis, P.2    Thomas, M.C.3
  • 52
    • 34547850679 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF) promotes activated mesangial cell survival via up-regulation of mitogen-activated protein kinase phosphatase-1 (MKP-1)
    • N. Wahab, D. Cox, A. Witherden and R. M. Mason: Connective tissue growth factor (CTGF) promotes activated mesangial cell survival via up-regulation of mitogen-activated protein kinase phosphatase-1 (MKP-1) Biochem J 406, 131-131 (2007)
    • (2007) Biochem J , vol.406 , pp. 131-131
    • Wahab, N.1    Cox, D.2    Witherden, A.3    Mason, R.M.4
  • 53
    • 33845612297 scopus 로고    scopus 로고
    • Connective tissue growth factor/CCN2 stimulates actin disassembly through Akt/protein kinase B-mediated phosphorylation and cytoplasmic translocation of p27 (Kip-1)
    • J. K. Crean, F. Furlong, D. Mitchell, E. McArdle, C. Godson and F. Martin: Connective tissue growth factor/CCN2 stimulates actin disassembly through Akt/protein kinase B-mediated phosphorylation and cytoplasmic translocation of p27 (Kip-1) Faseb J 20, 1712-1712 (2006)
    • (2006) Faseb J , vol.20 , pp. 1712-1712
    • Crean, J.K.1    Furlong, F.2    Mitchell, D.3    McArdle, E.4    Godson, C.5    Martin, F.6
  • 54
    • 0141994720 scopus 로고    scopus 로고
    • Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines
    • D. H. Hryciw, Y. Wang, O. Devuyst, C. A. Pollock, P. Poronnik and W. B. Guggino: Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines. J Biol Chem 278, 40169-40169 (2003)
    • (2003) J Biol Chem , vol.278 , pp. 40169-40169
    • Hryciw, D.H.1    Wang, Y.2    Devuyst, O.3    Pollock, C.A.4    Poronnik, P.5    Guggino, W.B.6
  • 55
    • 32844462174 scopus 로고    scopus 로고
    • Effect of inhibition of farnesylation and geranylgeranylation on renal fibrogenesis in vitro
    • DOI 10.1159/000088403
    • R. Masterson, K. Kelynack, T. Hewitson and G. Becker: Effect of inhibition of farnesylation and geranylgeranylation on renal fibrogenesis in vitro. Nephron Exp Nephrol 102, e19-29 (2006) (Pubitemid 43250935)
    • (2006) Nephron - Experimental Nephrology , vol.102 , Issue.1
    • Masterson, R.1    Kelynack, K.2    Hewitson, T.3    Becker, G.4
  • 57
    • 47249151503 scopus 로고    scopus 로고
    • Specific signals involved in the longterm maintenance of radiation-induced fibrogenic differentiation: A role for CCN2 and low concentration of TGF {beta}1
    • V. Haydont, B. L. Riser, J. Aigueperse and M. C. Vozenin-Brotons: Specific signals involved in the longterm maintenance of radiation-induced fibrogenic differentiation: a role for CCN2 and low concentration of TGF {beta}1. Am J Physiol Cell Physiol (2008)
    • (2008) Am J Physiol Cell Physiol
    • Haydont, V.1    Riser, B.L.2    Aigueperse, J.3    Vozenin-Brotons, M.C.4
  • 58
    • 41449093519 scopus 로고    scopus 로고
    • Effects of statins in patients with chronic kidney disease: Meta-analysis and meta-regression of randomised controlled trials
    • G. F. Strippoli, S. D. Navaneethan, D. W. Johnson, V. Perkovic, F. Pellegrini, A. Nicolucci and J. C. Craig: Effects of statins in patients with chronic kidney disease: meta-analysis and meta-regression of randomised controlled trials. Bmj 336, 645-645 (2008)
    • (2008) Bmj , vol.336 , pp. 645-645
    • Strippoli, G.F.1    Navaneethan, S.D.2    Johnson, D.W.3    Perkovic, V.4    Pellegrini, F.5    Nicolucci, A.6    Craig, J.C.7
  • 61
    • 0034951422 scopus 로고    scopus 로고
    • Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy
    • S. Wang, M. Denichilo, C. Brubaker and R. Hirschberg: Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy. Kidney Int 60, 96-96 (2001)
    • (2001) Kidney Int , vol.60 , pp. 96-96
    • Wang, S.1    Denichilo, M.2    Brubaker, C.3    Hirschberg, R.4
  • 62
    • 31544446026 scopus 로고    scopus 로고
    • Tubular expression of connective tissue growth factor correlates with interstitial fibrosis in type 2 diabetic nephropathy
    • T. Kobayashi, H. Okada, T. Inoue, Y. Kanno and H. Suzuki: Tubular expression of connective tissue growth factor correlates with interstitial fibrosis in type 2 diabetic nephropathy. Nephrol Dial Transplant 21, 548-548 (2006)
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 548-548
    • Kobayashi, T.1    Okada, H.2    Inoue, T.3    Kanno, Y.4    Suzuki, H.5
  • 63
    • 33748031093 scopus 로고    scopus 로고
    • Connective tissue growth factor plays an important role in advanced glycation end productinduced tubular epithelial-to-mesenchymal transition: Implications for diabetic renal disease
    • W. C. Burns, S. M. Twigg, J. M. Forbes, J. Pete, C. Tikellis, V. Thallas-Bonke, M. C. Thomas, M. E. Cooper and P. Kantharidis: Connective tissue growth factor plays an important role in advanced glycation end productinduced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease. J Am Soc Nephrol 17, 2484-2484 (2006)
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2484-2484
    • Burns, W.C.1    Twigg, S.M.2    Forbes, J.M.3    Pete, J.4    Tikellis, C.5    Thallas-Bonke, V.6    Thomas, M.C.7    Cooper, M.E.8    Kantharidis, P.9
  • 64
    • 35948932578 scopus 로고    scopus 로고
    • Transforming growth factor-beta/connective tissue growth factor axis in the kidney
    • W. Qi, X. Chen, P. Poronnik and C. A. Pollock: Transforming growth factor-beta/connective tissue growth factor axis in the kidney. Int J Biochem Cell Biol 40, 9-9 (2008)
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 9-9
    • Qi, W.1    Chen, X.2    Poronnik, P.3    Pollock, C.A.4
  • 65
    • 27644537013 scopus 로고    scopus 로고
    • The effect of connective tissue growth factor on human renal tubular epithelial cell transdifferentiation
    • C. Zhang, Z. Zhu and A. Deng: The effect of connective tissue growth factor on human renal tubular epithelial cell transdifferentiation. J Huazhong Univ Sci Technolog Med Sci 24, 350-350 (2004)
    • (2004) J Huazhong Univ Sci Technolog Med Sci , vol.24 , pp. 350-350
    • Zhang, C.1    Zhu, Z.2    Deng, A.3
  • 66
    • 9644255578 scopus 로고    scopus 로고
    • Connective tissue growth factor regulates the key events in tubular epithelial to myofibroblast transition in vitro
    • C. Zhang, X. Meng, Z. Zhu, J. Liu and A. Deng: Connective tissue growth factor regulates the key events in tubular epithelial to myofibroblast transition in vitro. Cell Biol Int 28, 863-863 (2004)
    • (2004) Cell Biol Int , vol.28 , pp. 863-863
    • Zhang, C.1    Meng, X.2    Zhu, Z.3    Liu, J.4    Deng, A.5
  • 67
    • 4344671694 scopus 로고    scopus 로고
    • Role of connective growth factor in plasminogen activator inhibitor-1 and fibronectin expression induced by transforming growth factor beta1 in renal tubular cells
    • C. Zhang, X. F. Meng, Z. H. Zhu, X. Yang and A. G. Deng: Role of connective growth factor in plasminogen activator inhibitor-1 and fibronectin expression induced by transforming growth factor beta1 in renal tubular cells. Chin Med J (Engl) 117, 990-990 (2004)
    • (2004) Chin Med J (Engl) , vol.117 , pp. 990-990
    • Zhang, C.1    Meng, X.F.2    Zhu, Z.H.3    Yang, X.4    Deng, A.G.5
  • 68
    • 2342512104 scopus 로고    scopus 로고
    • Role of connective tissue growth factor in renal tubular epithelial-myofibroblast transdifferentiation and extracellular matrix accumulation in vitro
    • C. Zhang, X. Meng, Z. Zhu, X. Yang and A. Deng: Role of connective tissue growth factor in renal tubular epithelial-myofibroblast transdifferentiation and extracellular matrix accumulation in vitro. Life Sci 75, 367-367 (2004)
    • (2004) Life Sci , vol.75 , pp. 367-367
    • Zhang, C.1    Meng, X.2    Zhu, Z.3    Yang, X.4    Deng, A.5
  • 71
    • 33644849416 scopus 로고    scopus 로고
    • Tranilast attenuates connective tissue growth factor-induced extracellular matrix accumulation in renal cells
    • W. Qi, X. Chen, S. Twigg, T. S. Polhill, R. E. Gilbert and C. A. Pollock: Tranilast attenuates connective tissue growth factor-induced extracellular matrix accumulation in renal cells. Kidney Int 69, 989-989 (2006)
    • (2006) Kidney Int , vol.69 , pp. 989-989
    • Qi, W.1    Chen, X.2    Twigg, S.3    Polhill, T.S.4    Gilbert, R.E.5    Pollock, C.A.6
  • 74
    • 0037229290 scopus 로고    scopus 로고
    • Tubular epithelial-myofibroblast transdifferentiation mechanisms in proximal tubule cells
    • H. Y. Lan: Tubular epithelial-myofibroblast transdifferentiation mechanisms in proximal tubule cells. Curr Opin Nephrol Hypertens 12, 25-25 (2003)
    • (2003) Curr Opin Nephrol Hypertens , vol.12 , pp. 25-25
    • Lan, H.Y.1
  • 75
    • 33644830593 scopus 로고    scopus 로고
    • Mechanisms of disease: Fibroblasts-a new look at an old problem
    • E. G. Neilson: Mechanisms of disease: Fibroblasts-a new look at an old problem. Nat Clin Pract Nephrol 2, 101-101 (2006)
    • (2006) Nat Clin Pract Nephrol , vol.2 , pp. 101-101
    • Neilson, E.G.1
  • 76
    • 34247533369 scopus 로고    scopus 로고
    • Phenotypic transitions and fibrosis in diabetic nephropathy
    • M. S. Simonson: Phenotypic transitions and fibrosis in diabetic nephropathy. Kidney Int 71, 846-846 (2007)
    • (2007) Kidney Int , vol.71 , pp. 846-846
    • Simonson, M.S.1
  • 77
    • 0036322007 scopus 로고    scopus 로고
    • Evidence that fibroblasts derive from epithelium during tissue fibrosis
    • M. Iwano, D. Plieth, T. M. Danoff, C. Xue, H. Okada and E. G. Neilson: Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 110, 341-341 (2002)
    • (2002) J Clin Invest , vol.110 , pp. 341-341
    • Iwano, M.1    Plieth, D.2    Danoff, T.M.3    Xue, C.4    Okada, H.5    Neilson, E.G.6
  • 78
    • 0347993932 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition in renal fibrogenesis: Pathologic significance, molecular mechanism, and therapeutic intervention
    • Y. Liu: Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention. J Am Soc Nephrol 15, 1-1 (2004)
    • (2004) J Am Soc Nephrol , vol.15 , pp. 1-1
    • Liu, Y.1
  • 79
    • 33845350114 scopus 로고    scopus 로고
    • A critical look at growth factors and epithelial-to-mesenchymal transition in the adult kidney: Interrelationships between growth factors that regulate EMT in the adult kidney
    • DOI 10.1159/000094963
    • N. A. Wahab and R. M. Mason: A critical look at growth factors and epithelial-to-mesenchymal transition in the adult kidney. Interrelationships between growth factors that regulate EMT in the adult kidney. Nephron Exp Nephrol 104, e129-34 (2006) (Pubitemid 44885059)
    • (2006) Nephron - Experimental Nephrology , vol.104 , Issue.4
    • Wahab, N.A.1    Mason, R.M.2
  • 80
    • 0043192745 scopus 로고    scopus 로고
    • GATA-and Smad1-dependent enhancers in the Smad7 gene differentially interpret bone morphogenetic protein concentrations
    • H. Benchabane and J. L. Wrana: GATA-and Smad1-dependent enhancers in the Smad7 gene differentially interpret bone morphogenetic protein concentrations. Mol Cell Biol 23, 6646-6646 (2003)
    • (2003) Mol Cell Biol , vol.23 , pp. 6646-6646
    • Benchabane, H.1    Wrana, J.L.2
  • 81
    • 16844371760 scopus 로고    scopus 로고
    • A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition
    • J. Yang, C. Dai and Y. Liu: A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition. J Am Soc Nephrol 16, 68-68 (2005)
    • (2005) J Am Soc Nephrol , vol.16 , pp. 68-68
    • Yang, J.1    Dai, C.2    Liu, Y.3
  • 82
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • M. Zeisberg, J. Hanai, H. Sugimoto, T. Mammoto, D. Charytan, F. Strutz and R. Kalluri: BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 9, 964-964 (2003)
    • (2003) Nat Med , vol.9 , pp. 964-964
    • Zeisberg, M.1    Hanai, J.2    Sugimoto, H.3    Mammoto, T.4    Charytan, D.5    Strutz, F.6    Kalluri, R.7
  • 84
    • 33644875787 scopus 로고    scopus 로고
    • Urinary connective tissue growth factor excretion correlates with clinical markers of renal disease in a large population of type 1 diabetic patients with diabetic nephropathy
    • T. Q. Nguyen, L. Tarnow, S. Andersen, P. Hovind, H. H. Parving, R. Goldschmeding and F. A. van Nieuwenhoven: Urinary connective tissue growth factor excretion correlates with clinical markers of renal disease in a large population of type 1 diabetic patients with diabetic nephropathy. Diabetes Care 29, 83-83 (2006)
    • (2006) Diabetes Care , vol.29 , pp. 83-83
    • Nguyen, T.Q.1    Tarnow, L.2    Andersen, S.3    Hovind, P.4    Parving, H.H.5    Goldschmeding, R.6    Van Nieuwenhoven, F.A.7
  • 86
    • 0344394902 scopus 로고    scopus 로고
    • Role of connective tissue growth factor in mediating hypertrophy of human proximal tubular cells induced by angiotensin II
    • B. C. Liu, J. Sun, Q. Chen, K. L. Ma, X. Z. Ruan and A. O. Phillips: Role of connective tissue growth factor in mediating hypertrophy of human proximal tubular cells induced by angiotensin II. Am J Nephrol 23, 429-429 (2003)
    • (2003) Am J Nephrol , vol.23 , pp. 429-429
    • Liu, B.C.1    Sun, J.2    Chen, Q.3    Ma, K.L.4    Ruan, X.Z.5    Phillips, A.O.6
  • 87
    • 33646005773 scopus 로고    scopus 로고
    • Connective tissue growth factor-mediated angiotensin II-induced hypertrophy of proximal tubular cells
    • B. C. Liu, L. Chen, J. Sun, H. Q. Huang, K. L. Ma, H. Liu, D. G. Liu and X. L. Zhang: Connective tissue growth factor-mediated angiotensin II-induced hypertrophy of proximal tubular cells. Nephron Exp Nephrol 103, e16-26 (2006)
    • (2006) Nephron Exp Nephrol , vol.103
    • Liu, B.C.1    Chen, L.2    Sun, J.3    Huang, H.Q.4    Ma, K.L.5    Liu, H.6    Liu, D.G.7    Zhang, X.L.8
  • 91
    • 0142089900 scopus 로고    scopus 로고
    • Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease
    • G. Jerums, S. Panagiotopoulos, J. Forbes, T. Osicka and M. Cooper: Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease. Arch Biochem Biophys 419, 55-55 (2003)
    • (2003) Arch Biochem Biophys , vol.419 , pp. 55-55
    • Jerums, G.1    Panagiotopoulos, S.2    Forbes, J.3    Osicka, T.4    Cooper, M.5
  • 93
    • 9644284528 scopus 로고    scopus 로고
    • Advanced glycation endproducts induce connective tissue growth factor-mediated renal fibrosis predominantly through transforming growth factor beta-independent pathway
    • G. Zhou, C. Li and L. Cai: Advanced glycation endproducts induce connective tissue growth factor-mediated renal fibrosis predominantly through transforming growth factor beta-independent pathway. Am J Pathol 165, 2033-2033 (2004)
    • (2004) Am J Pathol , vol.165 , pp. 2033-2033
    • Zhou, G.1    Li, C.2    Cai, L.3
  • 94
    • 26444547680 scopus 로고    scopus 로고
    • Advanced glycation end-productinduced mitogenesis and collagen production are dependent on angiotensin II and connective tissue growth factor in NRK-49F cells
    • C. I. Lee, J. Y. Guh, H. C. Chen, W. C. Hung, Y. L. Yang and L. Y. Chuang: Advanced glycation end-productinduced mitogenesis and collagen production are dependent on angiotensin II and connective tissue growth factor in NRK-49F cells. J Cell Biochem 95, 281-281 (2005)
    • (2005) J Cell Biochem , vol.95 , pp. 281-281
    • Lee, C.I.1    Guh, J.Y.2    Chen, H.C.3    Hung, W.C.4    Yang, Y.L.5    Chuang, L.Y.6


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