Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina

Diabetologia

Volumn 50, Issue 5, 2007, Pages 1089-1098

  Hughes, J M ^a   Kuiper, E J ^a   Klaassen, I ^a   Canning, P ^b   Stitt, A W ^b   Van Bezu, J ^c   Schalkwijk, C G ^c   Van Noorden, C J F ^a   Schlingemann, R O ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Advanced glycation end products; Aminoguanidine; Basement membrane; Connective tissue growth factor; Cystein rich protein 61; Diabetes mellitus; Diabetic retinopathy; Experimental; Extracellular matrix; Gene expression regulation

Indexed keywords

ADVANCED GLYCATION END PRODUCT; AMINOGUANIDINE; CONNECTIVE TISSUE GROWTH FACTOR; CYSTEINE RICH PROTEIN 61; GENE PRODUCT; GROWTH FACTOR; PROTEIN CCN3; UNCLASSIFIED DRUG; WNT 1 INDUCIBLE SIGNALING PATHWAY PROTEIN 1; WNT 1 INDUCIBLE SIGNALING PATHWAY PROTEIN 2; WNT 1 INDUCIBLE SIGNALING PATHWAY PROTEIN 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC RETINOPATHY; DOWN REGULATION; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; INFUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; RETINA; RNA ANALYSIS; STREPTOZOCIN DIABETES; WESTERN BLOTTING;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GENE EXPRESSION REGULATION; GLYCOSYLATION END PRODUCTS, ADVANCED; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C57BL; RATS; RATS, WISTAR; RETINA; RNA, MESSENGER;

EID: 34147117767     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-007-0621-4     Document Type: Article

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