A novel transforming growth factor β response element controls the expression of the connective tissue growth factor gene

Cell Growth and Differentiation

Volumn 7, Issue 4, 1996, Pages 469-480

  Grotendorst, Gary R ^a   Okochi, Hitoshi ^a   Hayashi, Nobukazu ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR; LUCIFERASE; PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; CATTLE; CELL GROWTH; CONNECTIVE TISSUE; GENE EXPRESSION; GENE SEQUENCE; HUMAN; HUMAN CELL; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; TISSUE REGENERATION;

3T3 CELLS; ANIMALS; ANISOMYCIN; BASE SEQUENCE; BINDING SITES; BLOTTING, NORTHERN; CYCLOHEXIMIDE; FIBROBLASTS; GENE DELETION; GENE EXPRESSION REGULATION; GROWTH SUBSTANCES; HUMANS; IMMEDIATE-EARLY PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; MICE; MITOGENS; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN SYNTHESIS INHIBITORS; PUROMYCIN; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0029808645     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Assoian, R. K., Komoriya, A., Meyers, C A., Miller, D. M., and Sporn, M. B. Transforming growth factor-β in human platelets: identification of a major storage site, purification, and characterization. J. Biol. Chem., 258: 7155-7160, 1983.
2. Assoian, R. K., Fleurdelys, B. E., Stevenson, H. C., Miller, P. J., Madtes, D K., Raines, E. W., Ross, R , and Sporn, M. B. Expression and secretion of type β transforming growth factor by activated human macrophages. Proc. Natl. Acad Sci. USA, 84: 6020-6024, 1987.
3. Grotendorst, G R., Smale, G., and Pencev, D Production of transforming growth factor β by human peripheral blood monocytes and neutrophils. J. Cell. Physiol., 140: 396-402, 1989.
4. Childs, C. B., Proper, J. A., Tucker, R. F., and Moses, H L. Serum contains a platelet derived transforming growth factor. Proc. Natl. Acad. Sci. USA, 79: 5312-5316, 1982.
5. Leof, E. B., Proper, J A., Gouston, A. S., Shipley, G. D., DiCorleto, P. E., and Moses, H. L. Introduction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor-β a proposed model for indirect mitogenesis involving autocrine activity Proc. Natl. Acad. Sci. USA, 83: 2453-2457, 1986.
6. Yaar, M., Peacocke, M., Cohen, M. S., and Gilchrest, B. A. Dissociation of proto-oncogene induction from growth response in normal human fibroblasts. J Cell Physiol, 145: 39-45, 1990.
7. Tucker, R. F., Shipley, G. D., Moses, H L., and Holley, R. W. Growth inhibitor from BSC-1 cells is closely related to platelet type β transforming growth factor. Science (Washington DC), 226: 705-707, 1984.
8. Heimark, R. L., Twardzik, D. R., and Schwartz, S. M. Inhibition of endothelial regeneration by type-β transforming growth factor from platelets Science (Washington DC), 233: 1078-1080, 1986.
9. Takehara, K., LeRoy, E C., and Grotendorst, G. R. TGF-β inhibition of endothelial cell proliferation: alteration of EGF binding and EGF-induced growth-regulatory (competence) gene expression. Cell, 49: 415-422, 1987.
10. Coffey, R. J., Jr., Bascom, C C, Sipes. N. J., Graves-Deal, R., Weissman, B. E., and Moses, H. L. Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor β. Mol. Cell. Biol., 8: 3088-3093, 1988.
11. Battegay, E. J., Raines, E. W., Seifert, R. A., Bowen-Pope, D. F., and Ross, R. TGF-β induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell, 63: 515-524, 1990.
12. Majack, R. A., Majesky, M. W., and Goodman, L. V. Role of PDGF-A chain expression in the control of vascular smooth muscle cell growth by TGF-β. J. Cell Biol , 111: 239-247, 1990.
13. Soma, Y., and Grotendorst, G. R. TGFβ stimulates primary human skin fibroblasts DNA synthesis via an autocrine production of PDGF-related peptides. J. Cell. Physiol., 140: 246-253, 1989.
14. Igarashi, A., Okochi, H., Bradham, D M., and Grotendorst, G. R. Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair. Mol. Biol. Cell., 4; 637-645, 1993.
15. Bradham, D. M., Igarashi, A., Potter, R. L., and Grotendorst, G. R. Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC induced immediate early gene product CEF-10 J. Cell. Biol., 114: 1285-1294, 1991.
16. O'Brien, T. P., Yang, G. P., Sanders, L., and Lau, L. F. Expression of cyr61, a growth factor-inducible immediate-early gene. Mol. Cell. Biol., 10: 3569-3577, 1990.
17. Ryseck, R. P., Macdonald-Bravo, H., Mattel, M. G., and Bravo, R. Structure, mapping and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein. Cell Growth & Differ., 2: 225-233, 1991.
18. Brunner, A., Chinn, J., Neubauer, M., and Purchio, A. F. Identification of a gene family regulated by transforming growth factor-β. DNA Cell Biol., 10: 293-300, 1991.
19. Simmons, D. L., Levy, D B., Yannoni, Y., and Enkson, R. L Identification of a phorbol ester-repressible v-src-inducible gene. Proc. Natl. Acad. Sci. USA, 86. 1178-1182, 1989.
20. Joliot, V., Martinerie, C., Dambrine, G., Plassiart, G., Brisac, M., Crochet, J., and Perbal, B Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas. Mol. Cell. Biol., 12: 10-21, 1992.
21. Mason, E. D., Konrad, K. D., Webb, C. D., and Marsh, J. L. Dorsal midline fate in Drosophila embryos requires twisted gastrulation. a gene encoding a secreted protein related to human connective tissue growth factor. Genes & Dev., 8: 1489-1501, 1994.
22. Oikarinen, J., Hatamochi, A., and de Crombrugghe, B. Separate binding sites for nuclear factor 1 and a CCAAT DNA binding factor in the mouse α2(1) collagen promoter J. Biol. Chem., 262: 11064-11070, 1987.
23. Riccio, A., Pedone, P. V., Lund, L. R., Olesen, T., Olsen, H. S., and Andreasen, P. A. Transforming growth factor β1 -responsive element: closely associated binding sites for USF and CCAAT-binding transcription factor-nuclear factor 1 in the type 1 plasminogen activator inhibitor gene. Mol. Cell. Biol., 12: 1846-1855, 1992.
24. Hou, X., Johnson, A. C., and Rosner, M. R. Induction of epidermal growth factor receptor gene transcription by TGF-β1: association with loss of protein binding to a negative regulatory element. Cell Growth & Differ., 5: 801-809, 1994.
25. Greenberg, M. E., and Ziff, E. B. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature (Lond.), 311: 433-438, 1984.
26. Cochran, B H., Reffel, A. C., and Stiles, C. D. Molecular cloning of gene sequences regulated by platelet-derived growth factor. Cell, 33: 939-947, 1983
27. Rollins, B. J., Morrison, E D., and Stiles, C. D. Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proc. Natl. Acad. Sci. USA, 85: 3738-3742, 1988.
28. Greenberg, M. E., Hermanowski, A. L., and Ziff, E. B. Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc and actin gene transcription. Mol. Cell. Biol., 6: 1050-1057, 1986.
29. Edwards, D. R., and Mahadevan, L. C Protein synthesis inhibitors differentially superinduce c-fos and c-jun by three distinct mechanisms: lack of evidence for labile repressors. EMBO J., 11: 2415-2424, 1992
30. Edwards, D. R , and Heath, J. K. Regulation of transcription by transforming growth factor-β. In: P. Cohen and J. G. Foulkes (eds.), The Hormonal Control Regulation of Gene Transcription, pp. 333-347, Amsterdam: Elsevier, 1991.
31. Mathews, L. S., and Vale, W. W. Expression cloning of an activin receptor, a predicted transmembrane serine kinase. Cell, 65: 973-982, 1991.
32. Ohtsuki, M , and Massagué, J. Evidence for the involvement of protein kinase activity in transforming growth factor-β signal transduction. Mol. Cell. Biol., 12: 261-265, 1992.
33. Williams, L. T. Signal transduction by the platelet-derived growth factor receptor Science (Washington DC), 243: 1564-1570, 1989.
34. Ullrich, A., and Schlessinger, J. Signal transduction by receptors with tyrosine kinase activity. Cell, 61: 203-212, 1990.
35. de Groot, R. P., and Kruijer, W. Transcriptional activation by TGF-β1 mediated by the DYAD symmetry element (DSE) and the TPA responsive element (TRE). Biochem. Biophys. Res. Commun., 168: 1074-1081, 1990
36. Kim, S-J., Angel, P., Lafyatis, R., Hattori, K., Kim, K. Y., Sporn, M. B., Karin, M., and Roberts, A. B. Autoinduction of transforming growth factor β1 is mediated by the AP-1 complex. Mol. Cell. Biol., 10: 1492-1497, 1990.
37. Kerr, L. D., Miller, D. B., and Matrisian, L. M. TGFβ1 inhibition of transin/stromelysin gene expression is mediated through a Fos binding sequence Cell, 61: 267-278, 1990.
38. Pietenpol, J. A., Munger, K., Howley, P. M., Stein, R. W., and Moses, H. L. Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor β1 and by the retinoblastoma gene product. Proc. Natl. Acad. Sci. USA, 88: 10227-10231, 1991.
39. Bork, P. The modular architecture of a new family of growth regulators related to connective tissue growth factor. FEBS Lett., 327: 125-130, 1993.
40. Igarashi, A., Nashiro, K., Kikuchi, K., Sato, S., Ihn, H., Grotendorst, G. R., and Takehara, K. Significant correlation between CTGF gene expression and skin sclerosis in tissue sections from patients with systemic sclerosis. J. Invest. Dermatol., 105. 280-284, 1995.
41. Delarco, J. E., and Todaro, G. J. Growth factors from murine sarcoma virus transformed cells. Proc. Natl. Acad. Sci. USA, 75: 4001-4005, 1978.
42. 1/S control of anchorage independent growth in the fibroblast cell cycle. J. Cell Biol, 115: 1572-1575, 1991.
43. Ferguson, E. L., and Anderson, K. V. Dorsal-ventral pattern formation in the Drosophila embryo: the role of zygotically active genes. Curr. Top. Dev. Biol., 25: 17-43, 1991.
44. St. Johnson, D., and Nusslein-Volhard, C. The origin of pattern and polarity in the Drosophila embryo. Cell, 68: 201-219, 1992.
45. Ferguson, E. L., and Anderson, K. V. Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. Cell, 71: 451-461, 1992.
46. Arora, K., Levine, M. S., and O'Connor, M. B. The screw gene encodes a ubiquitously expressed member of the TGF-β family required for specification of dorsal cell fates in the Drosophila embryo. Genes & Dev., 8: 2588-2601, 1994.
47. Celeste, A. J., Iannazzi, J. A , Taylor, R. C , Hewick, R. M., Rosen, V., Wang, E. A., and Wozney, J. M. Identification of transforming growth factor β family members present in bone-inductive protein purified from bovine bone. Proc. Natl. Acad. Sci USA, 87: 9843-9847, 1990.
48. Padgett, R. W., Wozney. J. M., and Gelbart, W. M. Human BMP sequences can confer normal dorsal ventral patterning in the Drosophila embryo. Proc. Natl. Acad. Sci. USA, 90: 2905-2909, 1993.
49. Chomczynski, P., and Sacchi, N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. BioChem., 162: 156-159, 1987.
50. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual, Ed. 2, pp. 14-19. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
51. Sanger, F., Nicklen, S., and Coulsen, A. R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA, 74: 5463-5467, 1977.
52. Abmayr, S. M., and Workman, J. L. Preparation of nuclear and cytoplasmic extracts from mammalian cells. In: F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith and K. Struhl (eds.), Current Protocols in Molecular Biology, Vol. 2, Suppl. 11, pp 12.1.1-12.1.9. New York: Greene Publishing and Wiley-Interscience, 1990.