Use of transgenic mice in UDP-glucuronosyltransferase (UGT) studies

Drug Metabolism Reviews

Volumn 42, Issue 1, 2010, Pages 123-131

  Ou, Zhimin ^a,b   Huang, Min ^b   Zhao, Lizi ^b   Xie, Wen ^a,c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Gene regulation; Humanized mice; Transcription factors; Transgenic mice; UGT

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; BETA NAPHTHOFLAVONE; CHRYSIN; CYTOCHROME P450 3A11; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 1A4; GLUCURONOSYLTRANSFERASE 1A6; HORMONE RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; PIRINIXIC ACID; PREGNANE X RECEPTOR; TRANSCRIPTION FACTOR NRF2;

DRUG GLUCURONIDATION; DRUG RESEARCH; GENE; GENE CONTROL; GENETIC TRANSFECTION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; REVIEW; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; UGT1A GENE; XENOBIOTIC METABOLISM;

EID: 74549116096     PISSN: 03602532     EISSN: 10979883     Source Type: Journal    
DOI: 10.3109/03602530903208983     Document Type: Review

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