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Volumn 26, Issue 9, 1998, Pages 860-867

Glucuronidation of amine substrates by purified and expressed UDP- glucuronosyltransferase proteins

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINE; GLUCURONOSYLTRANSFERASE; IMIPRAMINE; XENOBIOTIC AGENT;

EID: 0031706608     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (136)

References (64)
  • 3
    • 0018747509 scopus 로고
    • Purification of rat-liver microsomal UDP-glucuronyltransferase: Separation of two enzyme forms inducible by 3-methylcholanthrene or phenobarbital
    • Bock KW, Josting D, Lilienblum W and Pfeil H (1979) Purification of rat-liver microsomal UDP-glucuronyltransferase: Separation of two enzyme forms inducible by 3-methylcholanthrene or phenobarbital. Eur J Biochem 98:19-26.
    • (1979) Eur J Biochem , vol.98 , pp. 19-26
    • Bock, K.W.1    Josting, D.2    Lilienblum, W.3    Pfeil, H.4
  • 5
    • 0013958666 scopus 로고
    • The biochemistry of aromatic amines: The metabolism of 2-naphthylamine and 2-naphthylhydroxylamine derivatives
    • Boyland E and Manson D (1966) The biochemistry of aromatic amines: The metabolism of 2-naphthylamine and 2-naphthylhydroxylamine derivatives. Biochem J 101:84-102.
    • (1966) Biochem J , vol.101 , pp. 84-102
    • Boyland, E.1    Manson, D.2
  • 6
    • 0014339690 scopus 로고
    • Species differences in the metabolism of sulphadimethoxine
    • Bridges JW, Kibby MR, Walker SR and Williams RT (1961) Species differences in the metabolism of sulphadimethoxine. Biochem J 109:851-856.
    • (1961) Biochem J , vol.109 , pp. 851-856
    • Bridges, J.W.1    Kibby, M.R.2    Walker, S.R.3    Williams, R.T.4
  • 7
    • 0031573624 scopus 로고    scopus 로고
    • Characterization of rabbit UDP-glucuronosyltransferase UGT1A7: Tertiary amine glucuronidation is catalyzed by UGT1A7 and UGT1A4
    • Bruck M, Li Q, Lamb JG and Tukey RH (1997) Characterization of rabbit UDP-glucuronosyltransferase UGT1A7: Tertiary amine glucuronidation is catalyzed by UGT1A7 and UGT1A4. Arch Biochem Biophys 344:357-364.
    • (1997) Arch Biochem Biophys , vol.344 , pp. 357-364
    • Bruck, M.1    Li, Q.2    Lamb, J.G.3    Tukey, R.H.4
  • 8
    • 0028875109 scopus 로고
    • Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation
    • Burchell B, Brierley CH and Rance D (1995) Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation. Life Sci 57:1819-1831.
    • (1995) Life Sci , vol.57 , pp. 1819-1831
    • Burchell, B.1    Brierley, C.H.2    Rance, D.3
  • 10
    • 0002948741 scopus 로고
    • Diversity and independent regulation at the novel human UGT1 locus encoding 12 UDP-glucuronosyltransferase isozymes through duplication of both exon 1 and the upstream regulatory region
    • Cho J, Gholami N and Owens IS (1995) Diversity and independent regulation at the novel human UGT1 locus encoding 12 UDP-glucuronosyltransferase isozymes through duplication of both exon 1 and the upstream regulatory region. FASEB J 9:A1268.
    • (1995) FASEB J , vol.9
    • Cho, J.1    Gholami, N.2    Owens, I.S.3
  • 12
    • 0023110523 scopus 로고
    • The molecular basis of the inherited deficiency of androsterone UDP-glucuronyltransferase in Wistar rats
    • Corser RB, Coughtrie MW, Jackson MR and Burchell B (1987) The molecular basis of the inherited deficiency of androsterone UDP-glucuronyltransferase in Wistar rats. FEBS Lett 213:448-452.
    • (1987) FEBS Lett , vol.213 , pp. 448-452
    • Corser, R.B.1    Coughtrie, M.W.2    Jackson, M.R.3    Burchell, B.4
  • 13
    • 0025788493 scopus 로고
    • Glucuronidation of imipramine in rabbit and human liver microsomes: Assay conditions and interaction with other tertiary amine drugs
    • Coughtrie MW and Sharp S (1991) Glucuronidation of imipramine in rabbit and human liver microsomes: Assay conditions and interaction with other tertiary amine drugs. Biochem Pharmacol 42:1497-1501.
    • (1991) Biochem Pharmacol , vol.42 , pp. 1497-1501
    • Coughtrie, M.W.1    Sharp, S.2
  • 14
    • 0023242286 scopus 로고
    • Species-dependent glucuronidation of drugs by immobilized rabbit, rhesus monkey, and human UDP-glucuronyltransferases
    • Dulik DM and Fenselau C (1987) Species-dependent glucuronidation of drugs by immobilized rabbit, rhesus monkey, and human UDP-glucuronyltransferases. Drug Metab Dispos 15:473-477.
    • (1987) Drug Metab Dispos , vol.15 , pp. 473-477
    • Dulik, D.M.1    Fenselau, C.2
  • 15
    • 0027530118 scopus 로고
    • Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family
    • Ebner T and Burchell B (1993) Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family. Drug Metab Dispos 21:50-55.
    • (1993) Drug Metab Dispos , vol.21 , pp. 50-55
    • Ebner, T.1    Burchell, B.2
  • 16
    • 0027521059 scopus 로고
    • Human bilirubin UDP-glucuronosyltransferase catalyzes the glucuronidation of ethinylestradiol
    • Ebner T, Remmel RP and Burchell B (1993) Human bilirubin UDP-glucuronosyltransferase catalyzes the glucuronidation of ethinylestradiol. Mol Pharmacol 43:649-654.
    • (1993) Mol Pharmacol , vol.43 , pp. 649-654
    • Ebner, T.1    Remmel, R.P.2    Burchell, B.3
  • 17
    • 0028922238 scopus 로고
    • Drug-responsive and tissue-specific alternative expression of multiple first exons in rat UDP-glucuronosyltransferase family 1 (UGT1) gene complex
    • Emi Y, Ikushiro S and Iyanagi T (1995) Drug-responsive and tissue-specific alternative expression of multiple first exons in rat UDP-glucuronosyltransferase family 1 (UGT1) gene complex. J Biochem 117:392-399.
    • (1995) J Biochem , vol.117 , pp. 392-399
    • Emi, Y.1    Ikushiro, S.2    Iyanagi, T.3
  • 18
    • 0030044294 scopus 로고    scopus 로고
    • Xenobiotic responsive element-mediated transcriptional activation in the UDP-glucuronosyltransferase family 1 gene complex
    • Emi Y, Ikushiro S and Iyanagi T (1996) Xenobiotic responsive element-mediated transcriptional activation in the UDP-glucuronosyltransferase family 1 gene complex. J Biol Chem 271:3952-3958.
    • (1996) J Biol Chem , vol.271 , pp. 3952-3958
    • Emi, Y.1    Ikushiro, S.2    Iyanagi, T.3
  • 19
    • 0019180052 scopus 로고
    • Formation and urinary excretion of cyproheptadine in monkeys, chimpanzees and humans
    • Fischer LJ, Thies RL, Charkowski D and Darham KJ (1980) Formation and urinary excretion of cyproheptadine in monkeys, chimpanzees and humans. Drug Metab Dispos 8:422-424.
    • (1980) Drug Metab Dispos , vol.8 , pp. 422-424
    • Fischer, L.J.1    Thies, R.L.2    Charkowski, D.3    Darham, K.J.4
  • 20
    • 0022969633 scopus 로고
    • The metabolism of aromatic amines
    • Gorrod JW and Manson D (1986) The metabolism of aromatic amines. Xenobiotica 16:933-955.
    • (1986) Xenobiotica , vol.16 , pp. 933-955
    • Gorrod, J.W.1    Manson, D.2
  • 21
    • 0028948889 scopus 로고
    • Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides
    • Green MD, Bishop WP and Tephly TR (1995) Expressed human UGT1.4 protein catalyzes the formation of quaternary ammonium-linked glucuronides. Drug Metab Dispos 23:299-302.
    • (1995) Drug Metab Dispos , vol.23 , pp. 299-302
    • Green, M.D.1    Bishop, W.P.2    Tephly, T.R.3
  • 22
    • 0029084012 scopus 로고
    • Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols
    • Green MD, Clarke DJ, Oturu EM, Styczynski PB, Jackson MR, Burchell B and Tephly TR (1995) Cloning and expression of a rat liver phenobarbital-inducible UDP-glucuronosyltransferase (2B12) with specificity for monoterpenoid alcohols. Arch Biochem Biophys 322:460-468.
    • (1995) Arch Biochem Biophys , vol.322 , pp. 460-468
    • Green, M.D.1    Clarke, D.J.2    Oturu, E.M.3    Styczynski, P.B.4    Jackson, M.R.5    Burchell, B.6    Tephly, T.R.7
  • 23
    • 0031765698 scopus 로고    scopus 로고
    • Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3
    • Green MD, King CD, Mojarrabi B, Mackenzie PI and Tephly TR (1998) Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3. Drug Metab Dispos 26:507-512.
    • (1998) Drug Metab Dispos , vol.26 , pp. 507-512
    • Green, M.D.1    King, C.D.2    Mojarrabi, B.3    Mackenzie, P.I.4    Tephly, T.R.5
  • 24
    • 0028031001 scopus 로고
    • Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates
    • Green MD, Oturu EM and Tephly TR (1994) Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates. Drug Metab Dispos 22:799-805.
    • (1994) Drug Metab Dispos , vol.22 , pp. 799-805
    • Green, M.D.1    Oturu, E.M.2    Tephly, T.R.3
  • 25
    • 0023250996 scopus 로고
    • N-glucuronidation of carcinogenic aromatic amines catalyzed by rat hepatic microsomal preparations and purified rat liver undine 5′-diphosphate-glucuronosyltransferases
    • Green MD and Tephly TR (1987) N-glucuronidation of carcinogenic aromatic amines catalyzed by rat hepatic microsomal preparations and purified rat liver undine 5′-diphosphate-glucuronosyltransferases. Cancer Res 47:2028-2031.
    • (1987) Cancer Res , vol.47 , pp. 2028-2031
    • Green, M.D.1    Tephly, T.R.2
  • 26
    • 0029962074 scopus 로고    scopus 로고
    • Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein
    • Green MD and Tephly TR (1996) Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein. Drug Metab Dispos 24:356-363.
    • (1996) Drug Metab Dispos , vol.24 , pp. 356-363
    • Green, M.D.1    Tephly, T.R.2
  • 27
    • 0022006601 scopus 로고
    • Metabolic oxidation of carcinogenic arylamines by rat, dog, and human hepatic microsomes and by purified flavin-containing and cytochrome P-450 monooxygenases
    • Hammons GJ, Guengerich FP, Weis CC, Beland FA and Kadlubar FF (1985) Metabolic oxidation of carcinogenic arylamines by rat, dog, and human hepatic microsomes and by purified flavin-containing and cytochrome P-450 monooxygenases. Cancer Res 45:3578-3585.
    • (1985) Cancer Res , vol.45 , pp. 3578-3585
    • Hammons, G.J.1    Guengerich, F.P.2    Weis, C.C.3    Beland, F.A.4    Kadlubar, F.F.5
  • 28
    • 0025771648 scopus 로고
    • Isolation, sequence, and developmental expression of rat UGT2B2: The gene encoding a constitutive UDP glucuronosyltransferase that metabolizes etiocholanolone and androsterone
    • Haque SJ, Petersen DD, Neben DW and Mackenzie PI (1991) Isolation, sequence, and developmental expression of rat UGT2B2: The gene encoding a constitutive UDP glucuronosyltransferase that metabolizes etiocholanolone and androsterone. DNA Cell Biol 10:515-524.
    • (1991) DNA Cell Biol , vol.10 , pp. 515-524
    • Haque, S.J.1    Petersen, D.D.2    Neben, D.W.3    Mackenzie, P.I.4
  • 29
    • 0023812845 scopus 로고
    • Acetylator genotype and arylamine-induced carcinogenesis
    • Hein DW (1988) Acetylator genotype and arylamine-induced carcinogenesis. Biochim Biophys Acta 948:37-66.
    • (1988) Biochim Biophys Acta , vol.948 , pp. 37-66
    • Hein, D.W.1
  • 30
    • 0027980615 scopus 로고
    • N-glucuronidation reactions. III. Regioselectivity of N-glucuronidation of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole using human and rat recombinant UDP-glucuronosyltransferases stably expressed in V79 cells
    • Huskey SE, Magdalou J, Ouzzine M, Siest G and Chiu SH (1994) N-glucuronidation reactions. III. Regioselectivity of N-glucuronidation of methylbiphenyl tetrazole, methylbiphenyl triazole, and methylbiphenyl imidazole using human and rat recombinant UDP-glucuronosyltransferases stably expressed in V79 cells. Drug Metab Dispos 22:659-662.
    • (1994) Drug Metab Dispos , vol.22 , pp. 659-662
    • Huskey, S.E.1    Magdalou, J.2    Ouzzine, M.3    Siest, G.4    Chiu, S.H.5
  • 31
    • 0023137126 scopus 로고
    • Isolation and purification of two human liver UDP-glucuronosyltransferases
    • Irshaid YM and Tephly TR (1987) Isolation and purification of two human liver UDP-glucuronosyltransferases. Mol Pharmacol 31:27-34.
    • (1987) Mol Pharmacol , vol.31 , pp. 27-34
    • Irshaid, Y.M.1    Tephly, T.R.2
  • 32
    • 0017346090 scopus 로고
    • Influence of the aryl group on the reaction of glucuronides of N-arylacetylhydroxamic acids with polynucleotides
    • Irving CC (1977) Influence of the aryl group on the reaction of glucuronides of N-arylacetylhydroxamic acids with polynucleotides. Cancer Res 37:524-528.
    • (1977) Cancer Res , vol.37 , pp. 524-528
    • Irving, C.C.1
  • 33
    • 0027267719 scopus 로고
    • cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily
    • Jin CJ, Miners JO, Lillywhite KJ and Mackenzie PI (1993) cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily. Biochem Biophys Res Commun 194:496-503.
    • (1993) Biochem Biophys Res Commun , vol.194 , pp. 496-503
    • Jin, C.J.1    Miners, J.O.2    Lillywhite, K.J.3    Mackenzie, P.I.4
  • 35
    • 0017365046 scopus 로고
    • Hepatic microsomal N-glucuronidation and nucleic acid binding of N-hydroxy arylamines in relation to urinary bladder carcinogenesis
    • Kadlubar FF, Miller JA and Miller EC (1977) Hepatic microsomal N-glucuronidation and nucleic acid binding of N-hydroxy arylamines in relation to urinary bladder carcinogenesis. Cancer Res 37:805-817.
    • (1977) Cancer Res , vol.37 , pp. 805-817
    • Kadlubar, F.F.1    Miller, J.A.2    Miller, E.C.3
  • 36
    • 0019511348 scopus 로고
    • Alteration of urinary levels of the carcinogen, N-hydroxy-2-naphthylamine, and its N-glucuronide in the rat by control of urinary pH, inhibition of metabolic sulfation, and changes in biliary excretion
    • Kadlubar FF, Unruh LE, Flammang TJ, Sparks D, Mitchum RK and Mulder GJ (1981) Alteration of urinary levels of the carcinogen, N-hydroxy-2-naphthylamine, and its N-glucuronide in the rat by control of urinary pH, inhibition of metabolic sulfation, and changes in biliary excretion. Chem Biol Interact 33:129-147.
    • (1981) Chem Biol Interact , vol.33 , pp. 129-147
    • Kadlubar, F.F.1    Unruh, L.E.2    Flammang, T.J.3    Sparks, D.4    Mitchum, R.K.5    Mulder, G.J.6
  • 37
    • 0030221217 scopus 로고    scopus 로고
    • The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1
    • King CD, Green MD, Rios GR, Coffman BL, Owens IS, Bishop WP and Tephly TR (1996) The glucuronidation of exogenous and endogenous compounds by stably expressed rat and human UDP-glucuronosyltransferase 1.1. Arch Biochem Biophys 332:92-100.
    • (1996) Arch Biochem Biophys , vol.332 , pp. 92-100
    • King, C.D.1    Green, M.D.2    Rios, G.R.3    Coffman, B.L.4    Owens, I.S.5    Bishop, W.P.6    Tephly, T.R.7
  • 38
    • 0031034450 scopus 로고    scopus 로고
    • Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds
    • King CD, Rios GR, Green MD, MacKenzie PI and Tephly TR (1997) Comparison of stably expressed rat UGT1.1 and UGT2B1 in the glucuronidation of opioid compounds. Drug Metab Dispos 25:251-255.
    • (1997) Drug Metab Dispos , vol.25 , pp. 251-255
    • King, C.D.1    Rios, G.R.2    Green, M.D.3    MacKenzie, P.I.4    Tephly, T.R.5
  • 39
    • 0028037803 scopus 로고
    • Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: Differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Lamb JG, Straub P and Tukey RH (1994) Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: Differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochemistry 33:10513-10520.
    • (1994) Biochemistry , vol.33 , pp. 10513-10520
    • Lamb, J.G.1    Straub, P.2    Tukey, R.H.3
  • 41
    • 0023035858 scopus 로고
    • Rat liver UDP-glucuronosyltransferase: Sequence and expression of a cDNA encoding a phenobarbital-inducible form
    • Mackenzie PI (1986) Rat liver UDP-glucuronosyltransferase: Sequence and expression of a cDNA encoding a phenobarbital-inducible form. J Biol Chem 261:6119-6125.
    • (1986) J Biol Chem , vol.261 , pp. 6119-6125
    • Mackenzie, P.I.1
  • 42
    • 0023655381 scopus 로고
    • Rat liver UDP-glucuronosyltransferase: Identification of cDNAs encoding two enzymes which glucuronidate testosterone, dihydrotestosterone, and beta-estradiol
    • Mackenzie PI (1987) Rat liver UDP-glucuronosyltransferase: Identification of cDNAs encoding two enzymes which glucuronidate testosterone, dihydrotestosterone, and beta-estradiol. J Biol Chem 262:9744-9749.
    • (1987) J Biol Chem , vol.262 , pp. 9744-9749
    • Mackenzie, P.I.1
  • 43
    • 0025291023 scopus 로고
    • The cDNA sequence and expression of a variant 17 beta-hydroxysteroid UDP-glucuronosyltransferase
    • Mackenzie PI (1990) The cDNA sequence and expression of a variant 17 beta-hydroxysteroid UDP-glucuronosyltransferase. J Biol Chem 265:8699-8703.
    • (1990) J Biol Chem , vol.265 , pp. 8699-8703
    • Mackenzie, P.I.1
  • 45
    • 0022455779 scopus 로고
    • Genetic deficiency of androsterone UDP-glucuronosyltransferase activity in Wistar rats is due to the loss of enzyme protein
    • Matsui M and Nagai F (1986) Genetic deficiency of androsterone UDP-glucuronosyltransferase activity in Wistar rats is due to the loss of enzyme protein. Biochem J 234:139-144.
    • (1986) Biochem J , vol.234 , pp. 139-144
    • Matsui, M.1    Nagai, F.2
  • 46
    • 0013588037 scopus 로고    scopus 로고
    • cDNA cloning and characterization of the human UDP glucuronosyltransferase. UGT1A3
    • Mojarrabi B, Butler R and Mackenzie PI (1996) cDNA cloning and characterization of the human UDP glucuronosyltransferase. UGT1A3. Biochem Biophys Res Commun 225:785-790.
    • (1996) Biochem Biophys Res Commun , vol.225 , pp. 785-790
    • Mojarrabi, B.1    Butler, R.2    Mackenzie, P.I.3
  • 47
    • 0027978702 scopus 로고
    • Glucuronidation of carcinogenic arylamines and their N-hydroxy derivatives by rat and human phenol UDP-glucuronosyltransferase of the UGT1 gene complex
    • Orzechowski A, Schrenk D, Bock-Hennig BS and Bock KW (1994) Glucuronidation of carcinogenic arylamines and their N-hydroxy derivatives by rat and human phenol UDP-glucuronosyltransferase of the UGT1 gene complex. Carcinogenesis 15:1549-1553.
    • (1994) Carcinogenesis , vol.15 , pp. 1549-1553
    • Orzechowski, A.1    Schrenk, D.2    Bock-Hennig, B.S.3    Bock, K.W.4
  • 48
    • 0018637988 scopus 로고
    • N-glucuronidation of N-hydroxy aromatic amines: A mechanism for their transport and bladder-specific carcinogenicity
    • Poupko JM, Hearn WL and Radomski JL (1979) N-glucuronidation of N-hydroxy aromatic amines: A mechanism for their transport and bladder-specific carcinogenicity. Toxicol Appl Pharmacol 50:479-484.
    • (1979) Toxicol Appl Pharmacol , vol.50 , pp. 479-484
    • Poupko, J.M.1    Hearn, W.L.2    Radomski, J.L.3
  • 49
    • 0028044817 scopus 로고
    • A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids
    • Pritchard M, Foumel-Gigleux S, Siest G, Mackenzie P and Magdalou J (1994) A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids. Mol Pharmacol 45:42-50.
    • (1994) Mol Pharmacol , vol.45 , pp. 42-50
    • Pritchard, M.1    Foumel-Gigleux, S.2    Siest, G.3    Mackenzie, P.4    Magdalou, J.5
  • 50
    • 0022897428 scopus 로고
    • Isolation and purification of rat liver morphine UDP-glucuronosyltransferase
    • Puig JF and Tephly TR (1986) Isolation and purification of rat liver morphine UDP-glucuronosyltransferase. Mol Pharmacol 30:558-565.
    • (1986) Mol Pharmacol , vol.30 , pp. 558-565
    • Puig, J.F.1    Tephly, T.R.2
  • 51
    • 0025893724 scopus 로고
    • A quaternary ammonium glucuronide is the major metabolite of lamotrigine in guinea pigs
    • Remmel RP and Sinz MW (1991) A quaternary ammonium glucuronide is the major metabolite of lamotrigine in guinea pigs. Drug Metab Dispos 19:630-636.
    • (1991) Drug Metab Dispos , vol.19 , pp. 630-636
    • Remmel, R.P.1    Sinz, M.W.2
  • 52
    • 0026701911 scopus 로고
    • A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini
    • Ritter JK, Chen F, Sheen YY, Tran HM, Kimura S, Yeatman MT and Owens IS (1992) A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini. J Biol Chem 267:3257-3261.
    • (1992) J Biol Chem , vol.267 , pp. 3257-3261
    • Ritter, J.K.1    Chen, F.2    Sheen, Y.Y.3    Tran, H.M.4    Kimura, S.5    Yeatman, M.T.6    Owens, I.S.7
  • 53
    • 0026008487 scopus 로고
    • Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells
    • Ritter JK, Crawford JM and Owens IS (1991) Cloning of two human liver bilirubin UDP-glucuronosyltransferase cDNAs with expression in COS-1 cells. J Biol Chem 266:1043-1047.
    • (1991) J Biol Chem , vol.266 , pp. 1043-1047
    • Ritter, J.K.1    Crawford, J.M.2    Owens, I.S.3
  • 54
    • 0025321169 scopus 로고
    • Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells: 3,4-catechol estrogens and estriol as primary substrates
    • Ritter JK, Sheen YY and Owens IS (1990) Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells: 3,4-catechol estrogens and estriol as primary substrates. J Biol Chem 265:7900-7906.
    • (1990) J Biol Chem , vol.265 , pp. 7900-7906
    • Ritter, J.K.1    Sheen, Y.Y.2    Owens, I.S.3
  • 55
    • 0022627563 scopus 로고
    • Isolation and characterization of multiple forms of rat liver UDP-glucuronate glucuronosyltransferase
    • Roy Chowdhury J, Roy Chowdhury N, Falany CN, Tephly TR and Arias IM (1986) Isolation and characterization of multiple forms of rat liver UDP-glucuronate glucuronosyltransferase Biochem J 233:827-837.
    • (1986) Biochem J , vol.233 , pp. 827-837
    • Roy Chowdhury, J.1    Roy Chowdhury, N.2    Falany, C.N.3    Tephly, T.R.4    Arias, I.M.5
  • 56
    • 0344072129 scopus 로고
    • Bilirubin UDP-glucuronosyltransferase: Genetic defect of the hyperbilirubinemic Gunn rat, a model of Crigler-Najjar Syndrome type I
    • Fujita H ed AlphaMed Press, Dayton, Ohio
    • Sato H, Aono S, Danos O, Heard JM and Koiwai O (1994) Bilirubin UDP-glucuronosyltransferase: Genetic defect of the hyperbilirubinemic Gunn rat, a model of Crigler-Najjar Syndrome type I, in Regulation of Heme Protein Synthesis (Fujita H ed) pp 117-123, AlphaMed Press, Dayton, Ohio.
    • (1994) Regulation of Heme Protein Synthesis , pp. 117-123
    • Sato, H.1    Aono, S.2    Danos, O.3    Heard, J.M.4    Koiwai, O.5
  • 57
    • 0025370878 scopus 로고
    • Isolation and sequencing of rat liver bilirubin UDP-glucuronosyltransferase cDNA: Possible alternate splicing of a common primary transcript
    • Sato H, Koiwai O, Tanabe K and Kashiwamata S (1990) Isolation and sequencing of rat liver bilirubin UDP-glucuronosyltransferase cDNA: Possible alternate splicing of a common primary transcript. Biochem Biophys Res Commun 169:260-264.
    • (1990) Biochem Biophys Res Commun , vol.169 , pp. 260-264
    • Sato, H.1    Koiwai, O.2    Tanabe, K.3    Kashiwamata, S.4
  • 58
    • 0343161490 scopus 로고
    • The fate of aniline in the rabbit
    • Smith JN and Williams RT (1949) The fate of aniline in the rabbit. Biochem J 44:242-250.
    • (1949) Biochem J , vol.44 , pp. 242-250
    • Smith, J.N.1    Williams, R.T.2
  • 59
    • 0030800075 scopus 로고    scopus 로고
    • Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: Identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue
    • Strassburg CP, Oldhafer K, Manns MP and Tukey RH (1997) Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: Identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue. Mol Phamacol 52:212-220.
    • (1997) Mol Phamacol , vol.52 , pp. 212-220
    • Strassburg, C.P.1    Oldhafer, K.2    Manns, M.P.3    Tukey, R.H.4
  • 60
    • 0025824236 scopus 로고
    • Purification and properties of a rat liver phenobarbital-inducible 4-hydroxybiphenyl UDP-glucuronosyltransferase
    • Styczynski P, Green M, Puig J, Coffman B and Tephly T (1991) Purification and properties of a rat liver phenobarbital-inducible 4-hydroxybiphenyl UDP-glucuronosyltransferase. Mol Pharmacol 40:80-84.
    • (1991) Mol Pharmacol , vol.40 , pp. 80-84
    • Styczynski, P.1    Green, M.2    Puig, J.3    Coffman, B.4    Tephly, T.5
  • 61
    • 0024272026 scopus 로고
    • Endogenous substrates for UDP-glucuronosyltransferases
    • Tephly T, Green M, Puig J and Irshaid Y (1988) Endogenous substrates for UDP-glucuronosyltransferases. Xenobiotica 18:1201-1210.
    • (1988) Xenobiotica , vol.18 , pp. 1201-1210
    • Tephly, T.1    Green, M.2    Puig, J.3    Irshaid, Y.4
  • 64
    • 0022336971 scopus 로고
    • Separation, purification, and characterization of digitoxigenin-monodigitoxoside UDP-glucuronosyltransferase activity
    • von Meyerinck L, Coffman BL, Green MD, Kirkpatrick RB, Schmoldt A and Tephly TR (1985) Separation, purification, and characterization of digitoxigenin-monodigitoxoside UDP-glucuronosyltransferase activity. Drug Metab Dispos 13:700-704.
    • (1985) Drug Metab Dispos , vol.13 , pp. 700-704
    • Von Meyerinck, L.1    Coffman, B.L.2    Green, M.D.3    Kirkpatrick, R.B.4    Schmoldt, A.5    Tephly, T.R.6


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