Pharmacophore modeling and virtual screening for designing potential 5-Lipoxygenase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 3, 2010, Pages 1013-1018

  Aparoy, P ^a   Kumar Reddy, K ^a   Kalangi, Suresh K ^a   Chandramohan Reddy, T ^a   Reddanna, P ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

5 LOX; Asthma; Docking; Lipoxygenase inhibitor; Pharmacophore modeling; Virtual screening

Indexed keywords

LIPOXYGENASE INHIBITOR; ARACHIDONATE 5 LIPOXYGENASE;

ARTICLE; CATALYST; DATA BASE; DRUG ACTIVITY; DRUG SCREENING; HYDROGEN BOND; HYDROPHOBICITY; IC 50; MOLECULAR MODEL; PHARMACOPHORE; PREDICTION; VALIDATION PROCESS; CHEMICAL MODEL; CHEMICAL STRUCTURE; COMPARATIVE STUDY; COMPUTER SIMULATION; DRUG DESIGN; METABOLISM; PROCEDURES; SYNTHESIS;

ARACHIDONATE 5-LIPOXYGENASE; COMPUTER SIMULATION; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; LIPOXYGENASE INHIBITORS; MODELS, CHEMICAL; MODELS, MOLECULAR;

EID: 74049164272     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.047     Document Type: Article

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