Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation

Journal of Pharmacology and Experimental Therapeutics

Volumn 282, Issue 2, 1997, Pages 1094-1101

  Kirchner, T ^a   Argentieri, D C ^a   Barbone, A G ^a   Singer, M ^a   Steber, M ^a   Ansell, J ^a   Beers, S A ^a   Wachter, M P ^a   Wu, W ^a   Malloy, E ^a   Stewart, A ^a   Ritchie, D M ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CYCLOOXYGENASE 2 INHIBITOR; DEXAMETHASONE; INDOMETACIN; LEUKOTRIENE B4; LIPOXYGENASE INHIBITOR; N [5 (4 FLUOROPHENOXY) 2 THIENYL]METHANESULFONAMIDE; PROSTAGLANDIN E2; TENIDAP; THROMBOXANE B2; ZILEUTON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DOG; DRUG EFFECT; DRUG EFFICACY; ENZYME INDUCTION; ENZYME INHIBITION; EXUDATE; ICOSANOID METABOLISM; LEUKOCYTE COUNT; MEDIATOR RELEASE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARACHIDONATE 5-LIPOXYGENASE; CARRAGEENAN; CYCLOOXYGENASE INHIBITORS; DISEASE MODELS, ANIMAL; DOGS; EVALUATION STUDIES; FEMALE; INFLAMMATION; LEUKOTRIENE B4; LIPOXYGENASE INHIBITORS; MALE; SULFONAMIDES; THIOPHENES;

EID: 8544266039     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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