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Volumn 12, Issue 5, 2002, Pages 779-782
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Synthesis and activity of a new methoxytetrahydropyran derivative as dual cyclooxygenase-2/5-lipoxygenase inhibitor
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Author keywords
[No Author keywords available]
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Indexed keywords
ANTIINFLAMMATORY AGENT;
ARACHIDONATE 5 LIPOXYGENASE;
CYCLOOXYGENASE 2 INHIBITOR;
ENZYME INHIBITOR;
TETRAHYDROPYRAN DERIVATIVE;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANIMAL TISSUE;
ARTICLE;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG POTENCY;
DRUG SYNTHESIS;
ENZYME INHIBITION;
IN VITRO STUDY;
IN VIVO STUDY;
INFLAMMATION;
MALE;
NONHUMAN;
PHARMACOPHORE;
RAT;
STRUCTURE ACTIVITY RELATION;
ANIMALS;
ARACHIDONATE 5-LIPOXYGENASE;
CELLS, CULTURED;
CYCLOOXYGENASE 2;
CYCLOOXYGENASE 2 INHIBITORS;
CYCLOOXYGENASE INHIBITORS;
DINOPROSTONE;
GRANULOCYTES;
INHIBITORY CONCENTRATION 50;
ISOENZYMES;
LIPOXYGENASE INHIBITORS;
MALE;
MONOCYTES;
OSTEOSARCOMA;
PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES;
PYRAZOLES;
RATS;
RATS, WISTAR;
STRUCTURE-ACTIVITY RELATIONSHIP;
SULFONES;
SIGANUS;
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EID: 0037060906
PISSN: 0960894X
EISSN: None
Source Type: Journal
DOI: 10.1016/S0960-894X(02)00013-6 Document Type: Article |
Times cited : (81)
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References (31)
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