Discovery of new MurF inhibitors via pharmacophore modeling and QSAR analysis followed by in-silico screening

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 3, 2008, Pages 1218-1235

  Taha, Mutasem O ^a   Atallah, Naji ^a   Al Bakri, Amal G ^a   Paradis Bleau, Catherine ^b   Zalloum, Hiba ^a   Younis, Khaled S ^a   Levesque, Roger C ^b  

^a UNIVERSITY OF JORDAN   (Jordan)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

Experimental validation; In silico screening; MurF; Pharmacophore modeling; QSAR

Indexed keywords

ANTIINFECTIVE AGENT; MUSCLE RING FINGER PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER MODEL; CORRELATION ANALYSIS; DATA BASE; DRUG BINDING; DRUG INHIBITION; GENETIC ALGORITHM; LINEAR REGRESSION ANALYSIS; PHARMACOPHORE; PHYSICAL CHEMISTRY; PROTEIN BINDING; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

EID: 38849197951     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.10.076     Document Type: Article

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