Mitochondrial pharmacogenomics: barcode for antibiotic therapy

Drug Discovery Today

Volumn 15, Issue 1-2, 2010, Pages 33-39

  Pacheu Grau, David ^a   Gómez Durán, Aurora ^a   López Pérez, Manuel J ^a   Montoya, Julio ^a   Ruiz Pesini, Eduardo ^a,b  

^a INSTITUTO ARAGONÉS DE CIENCIAS DE LA SALUD   (Spain)

^b UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; AZITHROMYCIN; CHLORAMPHENICOL; ERYTHROMYCIN; MITOCHONDRIAL DNA; MITOCHONDRIAL RNA; OXAZOLIDINONE DERIVATIVE; RIBOSOME RNA; STREPTOMYCIN; TETRACYCLINE DERIVATIVE;

ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; BONE MARROW SUPPRESSION; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; DRUG SELECTIVITY; DRUG TARGETING; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HEARING LOSS; HUMAN; INFECTION; LACTIC ACIDOSIS; MITOCHONDRIAL GENETICS; MITOCHONDRIAL RESPIRATION; MUTATIONAL ANALYSIS; NEPHROTOXICITY; NONHUMAN; OPTIC NERVE DISEASE; OTOTOXICITY; OXIDATIVE PHOSPHORYLATION; PERIPHERAL NEUROPATHY; PHARMACOGENOMICS; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; REVIEW; RIBOSOME; RNA STRUCTURE; SIGNAL TRANSDUCTION;

ANTI-BACTERIAL AGENTS; CELL LINE, TRANSFORMED; DNA, MITOCHONDRIAL; DNA, RIBOSOMAL; GENETIC VARIATION; HUMANS; MITOCHONDRIA; MODELS, GENETIC; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PROTEIN BIOSYNTHESIS; RNA; RNA, RIBOSOMAL;

EID: 73749087417     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drudis.2009.10.008     Document Type: Review

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