Lateral-flow immunoassay for detecting drug-induced inhibition of mitochondrial DNA replication and mtDNA-encoded protein synthesis

Journal of Immunological Methods

Volumn 343, Issue 1, 2009, Pages 1-12

  Nadanaciva, Sashi ^a   Willis, John H ^a   Barker, Melissa L ^a   Gharaibeh, Dima ^a   Capaldi, Roderick A ^a   Marusich, Michael F ^a   Will, Yvonne ^b  

^a MitoSciences Inc   (United States)

^b PFIZER INC   (United States)

Author keywords

Antibacterials; Antiretrovirals; Lateral flow immunoassay; Mitochondria; Nucleoside reverse transcriptase inhibitors; Toxicity

Indexed keywords

ANTIINFECTIVE AGENT; ANTIRETROVIRUS AGENT; AZITHROMYCIN; CELL NUCLEUS DNA; CHLORAMPHENICOL; CYTOCHROME C OXIDASE; DIDANOSINE; DOXYCYCLINE; ERYTHROMYCIN; FRATAXIN; LINEZOLID; MINOCYCLINE; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; STAVUDINE; TETRACYCLINE; ZALCITABINE;

ARTICLE; CYTOSOL; DNA REPLICATION; DRUG MECHANISM; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; RIBOSOME; WESTERN BLOTTING;

ANTI-BACTERIAL AGENTS; ANTI-RETROVIRAL AGENTS; CELL LINE; DNA REPLICATION; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX IV; HUMANS; IMMUNOASSAY; IRON-BINDING PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PROTEIN BIOSYNTHESIS; REPRODUCIBILITY OF RESULTS;

EID: 60649087506     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2008.12.002     Document Type: Article

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