Functional characterization of the mitochondrial 12S rRNA C1494T mutation associated with aminoglycoside-induced and non-syndromic hearing loss

Nucleic Acids Research

Volumn 33, Issue 3, 2005, Pages 1132-1139

  Zhao, Hui ^a,b   Young, Wie Yen ^b   Yan, Qingfeng ^a   Li, Ronghua ^a   Cao, Juyang ^b   Wang, Qiuju ^b   Li, Xiaoming ^a   Peters, Jennifer L ^a   Han, Dongyi ^b   Guan, Min Xin ^a,b,c  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; ASCORBIC ACID; GLUTAMIC ACID; MALIC ACID; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; PAROMOMYCIN; RIBOSOME RNA; RNA 12S; SUCCINIC ACID; UNCLASSIFIED DRUG; RNA; RNA, MITOCHONDRIAL; RNA, RIBOSOMAL, 12S;

ARTICLE; CHINESE; CONTROLLED STUDY; DNA DETERMINATION; FAMILY; GENE MUTATION; HEARING LOSS; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MUTANT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; TOXICITY TESTING; BIOSYNTHESIS; CELL GROWTH; CELL LINE; CELL RESPIRATION; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GENETICS; PERCEPTION DEAFNESS; POINT MUTATION;

CELL GROWTH PROCESSES; CELL LINE; CELL RESPIRATION; HEARING LOSS, SENSORINEURAL; HUMANS; MITOCHONDRIAL PROTEINS; PAROMOMYCIN; POINT MUTATION; RNA; RNA, RIBOSOMAL;

EID: 20044362198     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gki262     Document Type: Article

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