메뉴 건너뛰기




Volumn 73, Issue 1, 1999, Pages 112-119

Glial cells mediate toxicity in glutathione-depleted mesencephalic cultures

Author keywords

Astrocytes; Buthionine sulfoximine; Glutathione; Lipoxygenase; Mesencephalic cultures; Microglia

Indexed keywords

BUTHIONINE SULFOXIMINE; GLUTATHIONE; REACTIVE OXYGEN METABOLITE;

EID: 0344758360     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0730112.x     Document Type: Article
Times cited : (51)

References (52)
  • 2
    • 0029818211 scopus 로고    scopus 로고
    • Glia: The not so innocent bystanders
    • Chao C. C., Hu S., and Peterson P. K. (1996) Glia: the not so innocent bystanders. J. Neurovirol 2, 234-239.
    • (1996) J. Neurovirol , vol.2 , pp. 234-239
    • Chao, C.C.1    Hu, S.2    Peterson, P.K.3
  • 3
    • 0029990439 scopus 로고    scopus 로고
    • Astrocytes protect neurons from hydrogen peroxide toxicity
    • Desagher S., Glowinski J., and Premont J. (1996) Astrocytes protect neurons from hydrogen peroxide toxicity. J. Neurosci. 16, 2553-2562.
    • (1996) J. Neurosci. , vol.16 , pp. 2553-2562
    • Desagher, S.1    Glowinski, J.2    Premont, J.3
  • 5
    • 0026704075 scopus 로고
    • Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group
    • Dexter D. T., Jenner P., Schapira A. H., and Marsden C. D. (1992) Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group. Ann. Neurol. 32 (Suppl.), S94-S100.
    • (1992) Ann. Neurol. , vol.32 , Issue.SUPPL.
    • Dexter, D.T.1    Jenner, P.2    Schapira, A.H.3    Marsden, C.D.4
  • 7
    • 0019121308 scopus 로고
    • Effect of striatal cells on in vitro maturation of mesencephalic dopaminergic neurones grown in serum-free conditions
    • di Porzio U., Daguet M. C., Glowinski J., and Prochiantz A. (1980) Effect of striatal cells on in vitro maturation of mesencephalic dopaminergic neurones grown in serum-free conditions. Nature 288, 370-373.
    • (1980) Nature , vol.288 , pp. 370-373
    • Di Porzio, U.1    Daguet, M.C.2    Glowinski, J.3    Prochiantz, A.4
  • 8
    • 0030772178 scopus 로고    scopus 로고
    • Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency
    • Druckarch B., Schepens C. A. M., Jongenelen J. C., Stoof C. H., and Langeveld C. H. (1997) Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency. Brain Res. 770, 123-130.
    • (1997) Brain Res. , vol.770 , pp. 123-130
    • Druckarch, B.1    Schepens, C.A.M.2    Jongenelen, J.C.3    Stoof, C.H.4    Langeveld, C.H.5
  • 9
    • 0026042368 scopus 로고
    • The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia
    • published erratum appears in J. Neurosci. (1992) 12, 685
    • Engele J. and Bohn M. C. (1991) The neurotrophic effects of fibroblast growth factors on dopaminergic neurons in vitro are mediated by mesencephalic glia [published erratum appears in J. Neurosci. (1992) 12, 685]. J. Neurosci. 11, 3070-3078.
    • (1991) J. Neurosci. , vol.11 , pp. 3070-3078
    • Engele, J.1    Bohn, M.C.2
  • 10
    • 0026484388 scopus 로고
    • The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
    • Fahn S. and Cohen G. (1992) The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann. Neurol. 32, 804-812.
    • (1992) Ann. Neurol. , vol.32 , pp. 804-812
    • Fahn, S.1    Cohen, G.2
  • 12
    • 0027463358 scopus 로고
    • Brain glia release factors with opposing actions upon neuronal survival
    • Giulian D., Vaca K., and Corpuz M. (1993) Brain glia release factors with opposing actions upon neuronal survival. J. Neurosci. 13, 29-37.
    • (1993) J. Neurosci. , vol.13 , pp. 29-37
    • Giulian, D.1    Vaca, K.2    Corpuz, M.3
  • 13
    • 0030059868 scopus 로고    scopus 로고
    • L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress
    • Han S.-K., Mytilineou C., and Cohen G. (1996) L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress. J. Neurochem. 66, 501-510.
    • (1996) J. Neurochem. , vol.66 , pp. 501-510
    • Han, S.-K.1    Mytilineou, C.2    Cohen, G.3
  • 14
    • 0029970588 scopus 로고    scopus 로고
    • Glutathione depletion is accompanied by increased neuronal nitric oxide synthase activity
    • Heales S. J., Bolanos J. P., and Clark J. B. (1996) Glutathione depletion is accompanied by increased neuronal nitric oxide synthase activity. Neurochem. Res. 21, 35-39.
    • (1996) Neurochem. Res. , vol.21 , pp. 35-39
    • Heales, S.J.1    Bolanos, J.P.2    Clark, J.B.3
  • 15
    • 0030918062 scopus 로고    scopus 로고
    • Basic fibroblast growth factor stimulation of glial cells protects dopamine neurons from 6-hydroxydopamine toxicity: Involvement of the glutathione system
    • Hou J.-G. G., Cohen G., and Mytilineou C. (1997) Basic fibroblast growth factor stimulation of glial cells protects dopamine neurons from 6-hydroxydopamine toxicity: involvement of the glutathione system. J. Neurochem. 69, 76-83.
    • (1997) J. Neurochem. , vol.69 , pp. 76-83
    • Hou, J.-G.G.1    Cohen, G.2    Mytilineou, C.3
  • 17
    • 0029751104 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of Parkinson's disease
    • Jenner P. and Olanow C. W. (1996) Oxidative stress and the pathogenesis of Parkinson's disease. Neurology 47 (Suppl.), S161-S170.
    • (1996) Neurology , vol.47 , Issue.SUPPL.
    • Jenner, P.1    Olanow, C.W.2
  • 18
    • 0032077890 scopus 로고    scopus 로고
    • Synergistic neurotoxic effects of combined treatments with cytokines in murine primary mixed neuron/glia cultures
    • Jeohn G. H., Kong L. Y., Wilson B., Hudson P., and Hong J. S. (1998) Synergistic neurotoxic effects of combined treatments with cytokines in murine primary mixed neuron/glia cultures. J. Neuroimmunol. 85, 1-10.
    • (1998) J. Neuroimmunol. , vol.85 , pp. 1-10
    • Jeohn, G.H.1    Kong, L.Y.2    Wilson, B.3    Hudson, P.4    Hong, J.S.5
  • 19
    • 0025770366 scopus 로고
    • Ascorbic acid in mesencephalic cultures: Effects on dopaminergic neuron development
    • Kalir H. H. and Mytilineou C. (1991) Ascorbic acid in mesencephalic cultures: effects on dopaminergic neuron development. J. Neurochem. 57, 458-464.
    • (1991) J. Neurochem. , vol.57 , pp. 458-464
    • Kalir, H.H.1    Mytilineou, C.2
  • 20
    • 0029084424 scopus 로고
    • Arachidonic acid as a neurotoxic and neurotrophic substance
    • Katsuki H. and Okuda S. (1995) Arachidonic acid as a neurotoxic and neurotrophic substance. Prog. Neurobiol. 46, 607-636.
    • (1995) Prog. Neurobiol. , vol.46 , pp. 607-636
    • Katsuki, H.1    Okuda, S.2
  • 22
    • 0030591434 scopus 로고    scopus 로고
    • Role of arachidonic acid metabolism in thymocyte apoptosis after irradiation
    • Korystov Y. N., Dobrovinskaya O. R., Shaposhnikova V. V., and Eidus L. (1996) Role of arachidonic acid metabolism in thymocyte apoptosis after irradiation. FEBS Lett. 388, 238-241.
    • (1996) FEBS Lett. , vol.388 , pp. 238-241
    • Korystov, Y.N.1    Dobrovinskaya, O.R.2    Shaposhnikova, V.V.3    Eidus, L.4
  • 23
    • 0030867994 scopus 로고    scopus 로고
    • A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion
    • Li Y., Maher P., and Schubert D. (1997) A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron 19, 453-463.
    • (1997) Neuron , vol.19 , pp. 453-463
    • Li, Y.1    Maher, P.2    Schubert, D.3
  • 25
    • 0023789193 scopus 로고
    • Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
    • McGeer P. L., Itagaki S., Boyes B. E., and McGeer E. G. (1988) Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 38, 1285-1291.
    • (1988) Neurology , vol.38 , pp. 1285-1291
    • McGeer, P.L.1    Itagaki, S.2    Boyes, B.E.3    McGeer, E.G.4
  • 26
    • 0026343403 scopus 로고
    • Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy
    • Meister A. (1991) Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy. Pharmacol. Ther. 51, 155-194.
    • (1991) Pharmacol. Ther. , vol.51 , pp. 155-194
    • Meister, A.1
  • 27
    • 0032169935 scopus 로고    scopus 로고
    • Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: Relevance to Parkinson's disease
    • Merad-Boudia M., Nicole A., Santiard-Baron D., Saille C., and Ceballos-Picot I. (1998) Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson's disease. Biochem. Pharmacol. 56, 645-655.
    • (1998) Biochem. Pharmacol. , vol.56 , pp. 645-655
    • Merad-Boudia, M.1    Nicole, A.2    Santiard-Baron, D.3    Saille, C.4    Ceballos-Picot, I.5
  • 28
    • 0030885416 scopus 로고    scopus 로고
    • Rescue of mesencephalic dopamine neurons by anticancer drug cytosine arabinoside
    • Michel P. P., Ruberg M., and Agid Y. (1997) Rescue of mesencephalic dopamine neurons by anticancer drug cytosine arabinoside. J. Neurochem. 69, 1499-1507.
    • (1997) J. Neurochem. , vol.69 , pp. 1499-1507
    • Michel, P.P.1    Ruberg, M.2    Agid, Y.3
  • 29
    • 0031985513 scopus 로고    scopus 로고
    • Microglia as effector cells in brain damage and repair: Focus on prostanoids and nitric oxide
    • Minghetti L. and Levi G. (1998) Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide. Prog. Neurobiol. 54, 99-125.
    • (1998) Prog. Neurobiol. , vol.54 , pp. 99-125
    • Minghetti, L.1    Levi, G.2
  • 30
    • 0028980156 scopus 로고
    • Transforming growth factor-beta 1 levels are elevated in the striatum and in ventricular cerebrospinal fluid in Parkinson's disease
    • Mogi M., Harada M., Kondo T., Narabayashi H., Riederer P., and Nagatsu T. (1995) Transforming growth factor-beta 1 levels are elevated in the striatum and in ventricular cerebrospinal fluid in Parkinson's disease. Neurosci. Lett. 193, 129-132.
    • (1995) Neurosci. Lett. , vol.193 , pp. 129-132
    • Mogi, M.1    Harada, M.2    Kondo, T.3    Narabayashi, H.4    Riederer, P.5    Nagatsu, T.6
  • 31
    • 0026021804 scopus 로고
    • Astrocytes, not neurons, produce docosahexaenoic acid (22:6ω-3) and arachidonic acid (20:4ω-6)
    • Moore S. A., Yoder E., Murphy S., Dutton G. R., and Spector A. A. (1991) Astrocytes, not neurons, produce docosahexaenoic acid (22:6ω-3) and arachidonic acid (20:4ω-6). J. Neurochem. 56, 518-524.
    • (1991) J. Neurochem. , vol.56 , pp. 518-524
    • Moore, S.A.1    Yoder, E.2    Murphy, S.3    Dutton, G.R.4    Spector, A.A.5
  • 32
    • 0024678458 scopus 로고
    • Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress
    • Murphy T. H., Miyamoto M., Sastre A., Schnaar R. L., and Coyle J. T. (1989) Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2, 1547-1558.
    • (1989) Neuron , vol.2 , pp. 1547-1558
    • Murphy, T.H.1    Miyamoto, M.2    Sastre, A.3    Schnaar, R.L.4    Coyle, J.T.5
  • 33
    • 0027362832 scopus 로고
    • Toxic and protective effects of L-DOPA on mesencephalic cell cultures
    • Mytilineou C., Han S.-K., and Cohen G. (1993) Toxic and protective effects of L-DOPA on mesencephalic cell cultures. J. Neurochem. 61, 1470-1478.
    • (1993) J. Neurochem. , vol.61 , pp. 1470-1478
    • Mytilineou, C.1    Han, S.-K.2    Cohen, G.3
  • 35
    • 0027081071 scopus 로고
    • +-damaged dopaminergic fibers by treatment of mesencephalic cultures with EGF and basic FGF
    • +-damaged dopaminergic fibers by treatment of mesencephalic cultures with EGF and basic FGF. Brain Res. 599, 83-97.
    • (1992) Brain Res. , vol.599 , pp. 83-97
    • Park, T.H.1    Mytilineou, C.2
  • 36
    • 0020308323 scopus 로고
    • Parkinson's disease: A disorder due to nigral glutathione deficiency?
    • Perry T. L., Godin D. V., and Hansen S. (1982) Parkinson's disease: a disorder due to nigral glutathione deficiency? Neurosci. Lett. 33, 305-310.
    • (1982) Neurosci. Lett. , vol.33 , pp. 305-310
    • Perry, T.L.1    Godin, D.V.2    Hansen, S.3
  • 37
  • 38
    • 0026030924 scopus 로고
    • Cellular and regional distribution of reduced glutathione in the nervous system of the rat: Histochemical localization by mercury orange and o-phthaldialdehyde-induced histofluorescence
    • Philbert M. A., Beiswanger C. M., Waters D. K., Reuhl K. R., and Lowndes H. E. (1991) Cellular and regional distribution of reduced glutathione in the nervous system of the rat: histochemical localization by mercury orange and o-phthaldialdehyde-induced histofluorescence. Toxicol. Appl. Pharmacol. 107, 215-227.
    • (1991) Toxicol. Appl. Pharmacol. , vol.107 , pp. 215-227
    • Philbert, M.A.1    Beiswanger, C.M.2    Waters, D.K.3    Reuhl, K.R.4    Lowndes, H.E.5
  • 39
    • 0025941476 scopus 로고
    • The presence of glutathione in primary neuronal and astroglial cultures from rat cerebral cortex and brain stem
    • Pileblad E., Eriksson P. S., and Hansson E. (1991) The presence of glutathione in primary neuronal and astroglial cultures from rat cerebral cortex and brain stem. J. Neural Transm. Gen. Sect. 86, 43-49.
    • (1991) J. Neural Transm. Gen. Sect. , vol.86 , pp. 43-49
    • Pileblad, E.1    Eriksson, P.S.2    Hansson, E.3
  • 40
    • 0027304229 scopus 로고
    • Arachidonic acid in cell signaling
    • Piomelli D. (1993) Arachidonic acid in cell signaling. Curr. Opin. Cell Biol. 5, 274-280.
    • (1993) Curr. Opin. Cell Biol. , vol.5 , pp. 274-280
    • Piomelli, D.1
  • 42
    • 0027421350 scopus 로고
    • Maintenance of neuronal glutathione by glial cells
    • Sagara J. I., Miura K., and Bannai S. (1993) Maintenance of neuronal glutathione by glial cells. J. Neurochem. 61, 1672-1676.
    • (1993) J. Neurochem. , vol.61 , pp. 1672-1676
    • Sagara, J.I.1    Miura, K.2    Bannai, S.3
  • 44
    • 0028075410 scopus 로고
    • Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
    • Sian J., Dexter D. T., Lees A. J., Daniel S., Agid Y., Javoy-Agid F., Jenner P., and Marsden C. D. (1994) Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann Neurol. 36, 348-355.
    • (1994) Ann Neurol. , vol.36 , pp. 348-355
    • Sian, J.1    Dexter, D.T.2    Lees, A.J.3    Daniel, S.4    Agid, Y.5    Javoy-Agid, F.6    Jenner, P.7    Marsden, C.D.8
  • 45
    • 0026774797 scopus 로고
    • Induction of nitric oxide synthase in glial cells
    • Simmons M. L. and Murphy S. (1992) Induction of nitric oxide synthase in glial cells. J. Neurochem. 59, 897-905.
    • (1992) J. Neurochem. , vol.59 , pp. 897-905
    • Simmons, M.L.1    Murphy, S.2
  • 46
    • 0023236818 scopus 로고
    • Histochemical evaluation of glutathione in brain
    • Slivka A., Mytilineou C., and Cohen G. (1987) Histochemical evaluation of glutathione in brain. Brain Res. 409, 275-284.
    • (1987) Brain Res. , vol.409 , pp. 275-284
    • Slivka, A.1    Mytilineou, C.2    Cohen, G.3
  • 47
    • 0025962972 scopus 로고
    • Nitric oxide as a neuronal messenger
    • Snyder S. H. and Bredt D. S. (1991) Nitric oxide as a neuronal messenger. Trends Pharmacol. Sci. 12, 125-128.
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 125-128
    • Snyder, S.H.1    Bredt, D.S.2
  • 48
    • 0026644192 scopus 로고
    • Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease
    • Sofic E., Lange K. W., Jellinger K., and Riederer P. (1992) Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease. Neurosci. Lett. 142, 128-130.
    • (1992) Neurosci. Lett. , vol.142 , pp. 128-130
    • Sofic, E.1    Lange, K.W.2    Jellinger, K.3    Riederer, P.4
  • 49
    • 0028332778 scopus 로고
    • Astrocyte-dependent and -independent phases of the development and survival of rat embryonic day 14 mesencephalic, dopaminergic neurons in culture
    • Takeshima T., Snimoda K., Sauve Y., and Commissiong J. W. (1994) Astrocyte-dependent and -independent phases of the development and survival of rat embryonic day 14 mesencephalic, dopaminergic neurons in culture. Neuroscience 60, 809-823.
    • (1994) Neuroscience , vol.60 , pp. 809-823
    • Takeshima, T.1    Snimoda, K.2    Sauve, Y.3    Commissiong, J.W.4
  • 50
    • 0029895338 scopus 로고    scopus 로고
    • Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis
    • Tang D. G., Chen Y. Q., and Honn K. V. (1996) Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis. Proc. Natl. Acad. Sci. USA 93, 5241-5246.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5241-5246
    • Tang, D.G.1    Chen, Y.Q.2    Honn, K.V.3
  • 51
    • 0014481378 scopus 로고
    • Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
    • Tietze F. (1969) Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27, 502-522.
    • (1969) Anal. Biochem. , vol.27 , pp. 502-522
    • Tietze, F.1
  • 52
    • 0024221329 scopus 로고
    • Neuron-glia interrelations
    • Vernadakis A. (1988) Neuron-glia interrelations. Int. Rev. Neurobiol. 30, 149-224.
    • (1988) Int. Rev. Neurobiol. , vol.30 , pp. 149-224
    • Vernadakis, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.