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Volumn 364, Issue 9435, 2004, Pages 722-724

Pathogenetic mechanisms of parkin in Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

PARKIN; TAU PROTEIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

EID: 4344681293     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(04)16901-8     Document Type: Short Survey
Times cited : (128)

References (33)
  • 1
    • 0032499264 scopus 로고    scopus 로고
    • Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
    • Kitada T, Asakawa S, Hattori N, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature. 392:1998;605-608
    • (1998) Nature , vol.392 , pp. 605-608
    • Kitada, T.1    Asakawa, S.2    Hattori, N.3
  • 2
    • 0031721141 scopus 로고    scopus 로고
    • Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q
    • Mori H, Kondo T, Yokochi M, et al. Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q. Neurology. 51:1998;890-892
    • (1998) Neurology , vol.51 , pp. 890-892
    • Mori, H.1    Kondo, T.2    Yokochi, M.3
  • 3
    • 0033933048 scopus 로고    scopus 로고
    • Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
    • Shimura H, Hattori N, Kubo S, et al. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet. 25:2000;302-305
    • (2000) Nat Genet , vol.25 , pp. 302-305
    • Shimura, H.1    Hattori, N.2    Kubo, S.3
  • 4
    • 18244412384 scopus 로고    scopus 로고
    • Molecular analysis of a novel ubiquitin-like protein (PARKIN) gene in Japanese families with AR-JP
    • Hattori N, Matsumine H, Kitada T, et al. Molecular analysis of a novel ubiquitin-like protein (PARKIN) gene in Japanese families with AR-JP. Ann Neurol. 44:1998;935-941
    • (1998) Ann Neurol , vol.44 , pp. 935-941
    • Hattori, N.1    Matsumine, H.2    Kitada, T.3
  • 5
    • 0342368772 scopus 로고    scopus 로고
    • Association between early-onset Parkinson's disease and mutations in the parkin gene
    • Lücking CB, Durr A, Bonifati V, et al. Association between early-onset Parkinson's disease and mutations in the parkin gene. N Engl J Med. 342:2000;1560-1567
    • (2000) N Engl J Med , vol.342 , pp. 1560-1567
    • Lücking, C.B.1    Durr, A.2    Bonifati, V.3
  • 6
    • 0037648357 scopus 로고    scopus 로고
    • Parkin mutations are frequent in patients with isolated early-onset parkinsonism
    • Periquet M, Latouche M, Lohmann E, et al. Parkin mutations are frequent in patients with isolated early-onset parkinsonism. Brain. 126:2003;1271-1278
    • (2003) Brain , vol.126 , pp. 1271-1278
    • Periquet, M.1    Latouche, M.2    Lohmann, E.3
  • 7
    • 0038662544 scopus 로고    scopus 로고
    • Parkin disease: A phenotypic study of a large case series
    • Khan NL, Graham E, Critchley P, et al. Parkin disease: a phenotypic study of a large case series. Brain. 126:2002;1279-1292
    • (2002) Brain , vol.126 , pp. 1279-1292
    • Khan, N.L.1    Graham, E.2    Critchley, P.3
  • 8
    • 10744226640 scopus 로고    scopus 로고
    • DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease
    • Hedrich K, Djarmati A, Schafer N, et al. DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease. Neurology. 62:2004;389-394
    • (2004) Neurology , vol.62 , pp. 389-394
    • Hedrich, K.1    Djarmati, A.2    Schafer, N.3
  • 9
    • 0035096967 scopus 로고    scopus 로고
    • Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene
    • Hilker R, Klein C, Ghaemi M, et al. Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene. Ann Neurol. 49:2001;367-376
    • (2001) Ann Neurol , vol.49 , pp. 367-376
    • Hilker, R.1    Klein, C.2    Ghaemi, M.3
  • 10
    • 0033933192 scopus 로고    scopus 로고
    • Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: Expanding the phenotype
    • Klein C, Pramstaller PP, Kis B, et al. Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: expanding the phenotype. Ann Neurol. 48:2000;65-71
    • (2000) Ann Neurol , vol.48 , pp. 65-71
    • Klein, C.1    Pramstaller, P.P.2    Kis, B.3
  • 11
    • 0038754178 scopus 로고    scopus 로고
    • Parkin mutations and susceptibility alleles in late-onset Parkinson's disease
    • Oliveira SA, Scott WK, Martin ER, et al. Parkin mutations and susceptibility alleles in late-onset Parkinson's disease. Ann Neurol. 53:2003;624-629
    • (2003) Ann Neurol , vol.53 , pp. 624-629
    • Oliveira, S.A.1    Scott, W.K.2    Martin, E.R.3
  • 12
    • 0037108727 scopus 로고    scopus 로고
    • Functional association of the parkin gene promoter with idiopathic Parkinson's disease
    • West AD, Maraganore D, Crook J, et al. Functional association of the parkin gene promoter with idiopathic Parkinson's disease. Hum Mol Genet. 11:2002;2787-2792
    • (2002) Hum Mol Genet , vol.11 , pp. 2787-2792
    • West, A.D.1    Maraganore, D.2    Crook, J.3
  • 13
    • 0042415580 scopus 로고    scopus 로고
    • How much phenotypic variation can be attributed to parkin genotype?
    • Lohmann E, Periquet M, Bonifati V, et al. How much phenotypic variation can be attributed to parkin genotype? Ann Neurol. 54:2003;176-185
    • (2003) Ann Neurol , vol.54 , pp. 176-185
    • Lohmann, E.1    Periquet, M.2    Bonifati, V.3
  • 14
    • 0034700158 scopus 로고    scopus 로고
    • Parkin functions as an E2 dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle associated protein, CDCrel-1
    • Zhang Y, Gao J, Chung KK, et al. Parkin functions as an E2 dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle associated protein, CDCrel-1. Proc Natl Acad Sci USA. 97:2000;13354-13359
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13354-13359
    • Zhang, Y.1    Gao, J.2    Chung, K.K.3
  • 15
    • 0035967883 scopus 로고    scopus 로고
    • An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
    • Imai Y, Soda M, Inoue H, et al. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell. 105:2001;891-902
    • (2001) Cell , vol.105 , pp. 891-902
    • Imai, Y.1    Soda, M.2    Inoue, H.3
  • 16
    • 0034776095 scopus 로고    scopus 로고
    • Parkin ubiquitinates the α-synuclein-interacting protein synphilin-1
    • Chung KK, Zhnag Y, Lim KL, et al. Parkin ubiquitinates the α-synuclein-interacting protein synphilin-1. Nat Med. 7:2001;1144-1150
    • (2001) Nat Med , vol.7 , pp. 1144-1150
    • Chung, K.K.1    Zhnag, Y.2    Lim, K.L.3
  • 17
    • 0035854437 scopus 로고    scopus 로고
    • Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implication for Parkinson's disease
    • Shimura H, Schlossmacher MG, Hattori N, et al. Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implication for Parkinson's disease. Science. 293:2001;263-269
    • (2001) Science , vol.293 , pp. 263-269
    • Shimura, H.1    Schlossmacher, M.G.2    Hattori, N.3
  • 18
    • 0037422010 scopus 로고    scopus 로고
    • Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons form kainite excitotoxicity
    • Staropoli JF, McDermott C, Martinat C, et al. Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons form kainite excitotoxicity. Neuron. 37:2003;735-749
    • (2003) Neuron , vol.37 , pp. 735-749
    • Staropoli, J.F.1    McDermott, C.2    Martinat, C.3
  • 19
    • 0037738525 scopus 로고    scopus 로고
    • Parkin binds to α-tubulin and increases their ubiquitination and degradation
    • Ren Y, Zhao J, Feng J. Parkin binds to α-tubulin and increases their ubiquitination and degradation. J Neurosci. 23:2003;3316-3324
    • (2003) J Neurosci , vol.23 , pp. 3316-3324
    • Ren, Y.1    Zhao, J.2    Feng, J.3
  • 20
    • 10744220754 scopus 로고    scopus 로고
    • The p38 subunit of the aminoacyl-tRNA synthase complex is a parkin substrate
    • Corti O, Hampe C, Koutnikova H, et al. The p38 subunit of the aminoacyl-tRNA synthase complex is a parkin substrate. Hum Mol Genet. 12:2003;1427-1437
    • (2003) Hum Mol Genet , vol.12 , pp. 1427-1437
    • Corti, O.1    Hampe, C.2    Koutnikova, H.3
  • 21
    • 0141995596 scopus 로고    scopus 로고
    • The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI
    • Huynh DP, Scoles DR, Neuyen D, et al. The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI. Hum Mol Genet. 12:2003;2587-2597
    • (2003) Hum Mol Genet , vol.12 , pp. 2587-2597
    • Huynh, D.P.1    Scoles, D.R.2    Neuyen, D.3
  • 23
    • 0037016687 scopus 로고    scopus 로고
    • Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain
    • Fallon L, Moreau F, Croft BG, et al. Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain. J Biol Chem. 277:2002;486-491
    • (2002) J Biol Chem , vol.277 , pp. 486-491
    • Fallon, L.1    Moreau, F.2    Croft, B.G.3
  • 24
    • 0033767459 scopus 로고    scopus 로고
    • Parkin is associated with actin filaments in neuronal and nonneuronal cells
    • Huynh DP, Scoles DR, Ho TH, et al. Parkin is associated with actin filaments in neuronal and nonneuronal cells. Ann Neurol 2000; 48: 737-44.
    • (2000) Ann Neurol , vol.48 , pp. 737-744
    • Huynh, D.P.1    Scoles, D.R.2    Ho, T.H.3
  • 25
    • 0142074728 scopus 로고    scopus 로고
    • Parkin is recruited to the centrosome in response to inhibition of proteasomes
    • Zhao J, Ren Y, Jiang Q, Feng J. Parkin is recruited to the centrosome in response to inhibition of proteasomes. J Cell Sci. 116:2003;4011-4019
    • (2003) J Cell Sci , vol.116 , pp. 4011-4019
    • Zhao, J.1    Ren, Y.2    Jiang, Q.3    Feng, J.4
  • 26
    • 0037368598 scopus 로고    scopus 로고
    • Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain
    • Sakata E, Yamaguchi Y, Kurimoto E, et al. Parkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domain. EMBO Rep. 4:2003;301-306
    • (2003) EMBO Rep , vol.4 , pp. 301-306
    • Sakata, E.1    Yamaguchi, Y.2    Kurimoto, E.3
  • 27
    • 10744221310 scopus 로고    scopus 로고
    • Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse
    • Itier J-M, Ibanez P, Mena MA, et al. Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse. Hum Mol Genet. 12:2003;2277-2291
    • (2003) Hum Mol Genet , vol.12 , pp. 2277-2291
    • Itier, J.-M.1    Ibanez, P.2    Mena, M.A.3
  • 28
    • 0141891953 scopus 로고    scopus 로고
    • Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
    • Goldberg MS, Fleming SM, Palacino JJ, et al. Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J Biol Chem. 278:2003;43628-43635
    • (2003) J Biol Chem , vol.278 , pp. 43628-43635
    • Goldberg, M.S.1    Fleming, S.M.2    Palacino, J.J.3
  • 29
    • 0037386532 scopus 로고    scopus 로고
    • Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
    • Greene JC, Whitworth AJ, Kuo I, et al. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc Natl Acad Sci USA. 100:2003;4078-4083
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4078-4083
    • Greene, J.C.1    Whitworth, A.J.2    Kuo, I.3
  • 30
    • 0037338634 scopus 로고    scopus 로고
    • Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
    • Darios F, Corti O, Lucking CB, et al. Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. Hum Mol Genet. 12:2003;517-526
    • (2003) Hum Mol Genet , vol.12 , pp. 517-526
    • Darios, F.1    Corti, O.2    Lucking, C.B.3
  • 31
    • 0034848395 scopus 로고    scopus 로고
    • Lewy bodies and parkinsonism in families with parkin mutations
    • Farrer M, Chan P, Chen R, et al. Lewy bodies and parkinsonism in families with parkin mutations. Ann Neurol. 50:2001;293-300
    • (2001) Ann Neurol , vol.50 , pp. 293-300
    • Farrer, M.1    Chan, P.2    Chen, R.3
  • 32
    • 0035957112 scopus 로고    scopus 로고
    • Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations
    • van de Warrenburg BP, Lammens M, Lucking CB, et al. Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations. Neurology. 56:2001;555-557
    • (2001) Neurology , vol.56 , pp. 555-557
    • Van De Warrenburg, B.P.1    Lammens, M.2    Lucking, C.B.3
  • 33
    • 0037468831 scopus 로고    scopus 로고
    • Parkin suppressed dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
    • Yang T, Nishimura I, Imai Y, et al. parkin suppressed dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Neuron. 37:2003;911-924
    • (2003) Neuron , vol.37 , pp. 911-924
    • Yang, T.1    Nishimura, I.2    Imai, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.