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Volumn 153, Issue 1, 1998, Pages 143-151

Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury

Author keywords

IL 1; IL 10; Inflammation; Injury; TNF

Indexed keywords

INTERLEUKIN 10;

EID: 0031713714     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1998.6877     Document Type: Article
Times cited : (247)

References (55)
  • 2
    • 9244260503 scopus 로고    scopus 로고
    • Attenuation of astroglial reactivity by interleukin-10
    • Balasingam, V., and V. W. Yong. 1996. Attenuation of astroglial reactivity by interleukin-10. J. Neurosci. 16(9): 2945-2955.
    • (1996) J. Neurosci. , vol.16 , Issue.9 , pp. 2945-2955
    • Balasingam, V.1    Yong, V.W.2
  • 3
    • 0027433633 scopus 로고
    • Interleukin 10 protects mice against staphylococcal enterotoxin B-induced lethal shock
    • Bean, A. G. D., R. A. Freiberg, S. Andrade, S. Menon, and A. Zlotnik. 1993. Interleukin 10 protects mice against staphylococcal enterotoxin B-induced lethal shock. Infect. Immun. 61(11): 4937-4939.
    • (1993) Infect. Immun. , vol.61 , Issue.11 , pp. 4937-4939
    • Bean, A.G.D.1    Freiberg, R.A.2    Andrade, S.3    Menon, S.4    Zlotnik, A.5
  • 4
    • 0029010133 scopus 로고
    • Differential regulation of astrocyte TNF-alpha expression by the cytokines TGF-beta, IL-6 and IL-10
    • Benveniste, E. N., L. P. Tang, and R. M. Law. 1995. Differential regulation of astrocyte TNF-alpha expression by the cytokines TGF-beta, IL-6 and IL-10. Int. J. Dev. Neurosci. 13: 341-349.
    • (1995) Int. J. Dev. Neurosci. , vol.13 , pp. 341-349
    • Benveniste, E.N.1    Tang, L.P.2    Law, R.M.3
  • 5
    • 0021199320 scopus 로고
    • Interleukin-1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells
    • Bevilacqua, M. P., J. S. Pober, G. R. Majeau, R. S. Cotran, and M. A. Jr. Gimbrone. 1984. Interleukin-1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells. J. Exp. Med. 160: 618-623.
    • (1984) J. Exp. Med. , vol.160 , pp. 618-623
    • Bevilacqua, M.P.1    Pober, J.S.2    Majeau, G.R.3    Cotran, R.S.4    Gimbrone M.A., Jr.5
  • 6
    • 0022409579 scopus 로고
    • Interleukin-1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes and related leukocyte cell lines
    • Bevilacqua, M. P., J. S. Pober, M. E. Wheeler, R. S. Cotran, and M. A. Jr. Gimbrone. 1985. Interleukin-1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes and related leukocyte cell lines. J. Clin. Invest. 76: 2003-2011.
    • (1985) J. Clin. Invest. , vol.76 , pp. 2003-2011
    • Bevilacqua, M.P.1    Pober, J.S.2    Wheeler, M.E.3    Cotran, R.S.4    Gimbrone M.A., Jr.5
  • 7
    • 0027248910 scopus 로고
    • Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10
    • Bogdan, C., and C. Nathan. 1993. Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10. Ann. N.Y. Acad. Sci. 685: 713-739.
    • (1993) Ann. N.Y. Acad. Sci. , vol.685 , pp. 713-739
    • Bogdan, C.1    Nathan, C.2
  • 8
    • 0026457998 scopus 로고
    • Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-β and interleukin-10
    • Bogdan, C., J. Paik, Y. Vodovotz, and C. Nathan. 1992. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-β and interleukin-10. J. Biol. Chem. 267(32): 23301-23308.
    • (1992) J. Biol. Chem. , vol.267 , Issue.32 , pp. 23301-23308
    • Bogdan, C.1    Paik, J.2    Vodovotz, Y.3    Nathan, C.4
  • 9
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 10
    • 0030607219 scopus 로고    scopus 로고
    • Differential effects of Th1 and Th2 derived cytokines on NGF synthesis by mouse astrocytes
    • Brodie, C. 1996. Differential effects of Th1 and Th2 derived cytokines on NGF synthesis by mouse astrocytes. FEBS Lett. 394: 117-120.
    • (1996) FEBS Lett. , vol.394 , pp. 117-120
    • Brodie, C.1
  • 11
    • 0028287092 scopus 로고
    • Interleukin 10 (IL-10) upregulates IL-1 receptor antagonist production from lipopolysaccharide-stimulated human polymorphonuclear leukocytes by delaying mRNAdegradation
    • Cassatella, M. A., L. Meda, S. Gasperini, F. Calzetti, and S. Bonora. 1994. Interleukin 10 (IL-10) upregulates IL-1 receptor antagonist production from lipopolysaccharide-stimulated human polymorphonuclear leukocytes by delaying mRNAdegradation. J. Exp. Med. 179:1695-1699.
    • (1994) J. Exp. Med. , vol.179 , pp. 1695-1699
    • Cassatella, M.A.1    Meda, L.2    Gasperini, S.3    Calzetti, F.4    Bonora, S.5
  • 12
    • 0029078126 scopus 로고
    • Tumor necrosis factor-alpha production by human fetal microglial cells: Regulation by other cytokines
    • Chao, C. C., S. Hu, W. S. Sheng, and P. K Peterson. 1995. Tumor necrosis factor-alpha production by human fetal microglial cells: Regulation by other cytokines. Dev. Neurosci. 17: 97-105.
    • (1995) Dev. Neurosci. , vol.17 , pp. 97-105
    • Chao, C.C.1    Hu, S.2    Sheng, W.S.3    Peterson, P.K.4
  • 13
    • 0027945338 scopus 로고
    • Neutrophil accumulation after traumatic brain injury in rats: Comparison of weight drop and controlled cortical impact models
    • Clark, R. S., J. K. Schiding, S. L. Kaczorowski, D. W. Marion, and P. M. Kochanek. 1994. Neutrophil accumulation after traumatic brain injury in rats: Comparison of weight drop and controlled cortical impact models. J. Neurotrauma. 11:499-506.
    • (1994) J. Neurotrauma. , vol.11 , pp. 499-506
    • Clark, R.S.1    Schiding, J.K.2    Kaczorowski, S.L.3    Marion, D.W.4    Kochanek, P.M.5
  • 14
    • 0024508256 scopus 로고
    • Experimental fluid percussion brain injury: Vascular disruption and neuronal and glial alterations
    • Cortez, S. C., T. K. McIntosh, and L. J. Noble. 1989. Experimental fluid percussion brain injury: vascular disruption and neuronal and glial alterations. Brain Res. 482: 271-282.
    • (1989) Brain Res. , vol.482 , pp. 271-282
    • Cortez, S.C.1    McIntosh, T.K.2    Noble, L.J.3
  • 15
    • 0028783962 scopus 로고
    • Staphylococcal enterotoxin B and tumor necrosis factor-alpha-induced relapses of experimental allergic encephalomyelitis: Protection by transforming growth factor-beta and interleukin-10
    • Crisi, G. M., L. Santambrogio, G. M. Hochwald, S. R. Smith, J. A. Carlino, and G. J. Thorbecke. 1995. Staphylococcal enterotoxin B and tumor necrosis factor-alpha-induced relapses of experimental allergic encephalomyelitis: Protection by transforming growth factor-beta and interleukin-10. Eur. J. Immunol. 25(11): 3035-3040.
    • (1995) Eur. J. Immunol. , vol.25 , Issue.11 , pp. 3035-3040
    • Crisi, G.M.1    Santambrogio, L.2    Hochwald, G.M.3    Smith, S.R.4    Carlino, J.A.5    Thorbecke, G.J.6
  • 16
    • 0026094306 scopus 로고
    • Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
    • de Waal Malefyt, R., J. Abrams, B. Bennett, C. G. Figdor, and J. E. de Vries. 1991. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174: 1209-1220.
    • (1991) J. Exp. Med. , vol.174 , pp. 1209-1220
    • De Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    De Vries, J.E.5
  • 17
    • 0026786959 scopus 로고
    • Platelet-activating factor antagonists limit glycine changes and behavioral deficits after brain trauma
    • Faden, A. I., and P. A. Tzendzalian. 1992. Platelet-activating factor antagonists limit glycine changes and behavioral deficits after brain trauma. Am. J. Physiol. 263: R909-R914.
    • (1992) Am. J. Physiol. , vol.263
    • Faden, A.I.1    Tzendzalian, P.A.2
  • 20
    • 0009614816 scopus 로고
    • The consequences of inflammation after injury to the central nervous system
    • (S. K. Salzman and A. I. Faden, Eds.), Oxford Univ. Press, New York
    • Giulian, D. 1994. The consequences of inflammation after injury to the central nervous system. In The Neurobiology of Central Nervous System Trauma (S. K. Salzman and A. I. Faden, Eds.), pp. 155-164. Oxford Univ. Press, New York.
    • (1994) The Neurobiology of Central Nervous System Trauma , pp. 155-164
    • Giulian, D.1
  • 21
    • 0027138139 scopus 로고
    • Reactive mononuclear phagocytes release neurotoxins after ischemic and traumatic injury to the central nervous system
    • Giulian, D., M. Corpuz, S. Chapman, M. Mansouri, and C. Robertson. 1993. Reactive mononuclear phagocytes release neurotoxins after ischemic and traumatic injury to the central nervous system. J. Neurosci. Res. 36: 681-693.
    • (1993) J. Neurosci. Res. , vol.36 , pp. 681-693
    • Giulian, D.1    Corpuz, M.2    Chapman, S.3    Mansouri, M.4    Robertson, C.5
  • 22
    • 0030199288 scopus 로고    scopus 로고
    • Activated microglia are the principal glial source of thromboxane in the central nervous system
    • Giulian, D., M. Corpuz, B. Richmond, E. Wendt, and E. R. Hall. 1996. Activated microglia are the principal glial source of thromboxane in the central nervous system. Neurochem. Int. 29: 65-76.
    • (1996) Neurochem. Int. , vol.29 , pp. 65-76
    • Giulian, D.1    Corpuz, M.2    Richmond, B.3    Wendt, E.4    Hall, E.R.5
  • 24
    • 0027959650 scopus 로고
    • Two inhibitors of pro-inflammatory cytokine release, interleukin-10 and interleukin-4, have contrasting effects on release of soluble p75 tumor necrosis factor receptor by cultured monocytes
    • Joyce, D. A., D. P. Gibbons, P. Green, J. H. Steer, M. Feldman, and F. M. Brennan. 1994. Two inhibitors of pro-inflammatory cytokine release, interleukin-10 and interleukin-4, have contrasting effects on release of soluble p75 tumor necrosis factor receptor by cultured monocytes. Eur. J. Immunol. 24: 2699-2705.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2699-2705
    • Joyce, D.A.1    Gibbons, D.P.2    Green, P.3    Steer, J.H.4    Feldman, M.5    Brennan, F.M.6
  • 25
    • 0028033560 scopus 로고
    • Transforming growth factor-beta and interleukin-10, but not interleukin-4, down-regulate procoagulant activity and tissue factor expression in human monocyte-derived macrophages
    • Jungi, T. W., M. Brcic, S. Eperon, and S. Albrecht. 1994. Transforming growth factor-beta and interleukin-10, but not interleukin-4, down-regulate procoagulant activity and tissue factor expression in human monocyte-derived macrophages. Thromb. Res. 76: 463-474.
    • (1994) Thromb. Res. , vol.76 , pp. 463-474
    • Jungi, T.W.1    Brcic, M.2    Eperon, S.3    Albrecht, S.4
  • 26
    • 0003144997 scopus 로고    scopus 로고
    • Astrocytic responses to central nervous system trauma
    • (S. K. Salzman and A. I. Faden, Eds.), Oxford Univ. Press, New York
    • Kimelberg, H. K., and M. D. Norenberg. Astrocytic responses to central nervous system trauma. In The Neurobiology of Central Nervous System Trauma (S. K. Salzman and A. I. Faden, Eds.), pp. 193-208. Oxford Univ. Press, New York.
    • The Neurobiology of Central Nervous System Trauma , pp. 193-208
    • Kimelberg, H.K.1    Norenberg, M.D.2
  • 27
    • 0030442779 scopus 로고    scopus 로고
    • Systemically (but not intrathecally) administered IL-10 attenuates pathophysiologic alterations in experimental pneumoccal meningitis
    • Koedel, U., A. Bernatowicz, K. Frei, A. Fontana, and H.-W. Pfister. 1996. Systemically (but not intrathecally) administered IL-10 attenuates pathophysiologic alterations in experimental pneumoccal meningitis. J. Immunol. 157: 5185-5191.
    • (1996) J. Immunol. , vol.157 , pp. 5185-5191
    • Koedel, U.1    Bernatowicz, A.2    Frei, K.3    Fontana, A.4    Pfister, H.-W.5
  • 28
    • 0028944754 scopus 로고
    • IL-10 inhibits the adhesion of leukocytic cells to IL-1-activated human endothelial cells
    • Krakauer, T. 1995. IL-10 inhibits the adhesion of leukocytic cells to IL-1-activated human endothelial cells. Immunol. Lett. 45(1-2): 61-65.
    • (1995) Immunol. Lett. , vol.45 , Issue.1-2 , pp. 61-65
    • Krakauer, T.1
  • 29
    • 0028604491 scopus 로고
    • Surfactant protein a stimulation of inflammatory cytokine and immunoglobulin production
    • Kremlev, S. G., and D. S. Phelps. 1994. Surfactant protein A stimulation of inflammatory cytokine and immunoglobulin production. Am. J. Physiol. 267: L712-L719.
    • (1994) Am. J. Physiol. , vol.267
    • Kremlev, S.G.1    Phelps, D.S.2
  • 30
    • 0028331278 scopus 로고
    • The early reactions of non-neuronal cells to brain injury
    • Landis, D. M. 1994. The early reactions of non-neuronal cells to brain injury. Annu. Rev. Neurosci. 17: 133-151.
    • (1994) Annu. Rev. Neurosci. , vol.17 , pp. 133-151
    • Landis, D.M.1
  • 31
    • 0028084441 scopus 로고
    • Interleukin-10 prevents spontaneous death of germinal center B cells by induction of the bcl-2 protein
    • Levy, Y., and J.-C. Brouet. 1994. Interleukin-10 prevents spontaneous death of germinal center B cells by induction of the bcl-2 protein. J. Clin. Invest. 93: 424-428.
    • (1994) J. Clin. Invest. , vol.93 , pp. 424-428
    • Levy, Y.1    Brouet, J.-C.2
  • 32
    • 0029956457 scopus 로고    scopus 로고
    • Regulation of microglial activation by TGF-beta, IL-10, and CSF-1
    • Lodge, P. A., and S. Sriram. 1996. Regulation of microglial activation by TGF-beta, IL-10, and CSF-1. J. Leukoc. Biol. 60(4): 502-508.
    • (1996) J. Leukoc. Biol. , vol.60 , Issue.4 , pp. 502-508
    • Lodge, P.A.1    Sriram, S.2
  • 33
    • 0023223416 scopus 로고
    • Ventricular fluid interleukin-1 activity in patients with head injury
    • McClain, C. J., D. Cohen, L. Ott, C. A. Dinarello, and B. Young. 1987. Ventricular fluid interleukin-1 activity in patients with head injury. J. Lab. Clin. Med. 110: 48-54.
    • (1987) J. Lab. Clin. Med. , vol.110 , pp. 48-54
    • McClain, C.J.1    Cohen, D.2    Ott, L.3    Dinarello, C.A.4    Young, B.5
  • 35
    • 0026746681 scopus 로고
    • Recombinant human tumor necrosis factor a constricts pial arterioles and increases blood-brain barrier permeability in newborn piglets
    • Megyeri, P., C. S. Abraham, P. Temesvari, J. Kovacs, T. Vas, and C. P. Speer. 1992. Recombinant human tumor necrosis factor a constricts pial arterioles and increases blood-brain barrier permeability in newborn piglets. Neurosci. Lett. 148: 137-140.
    • (1992) Neurosci. Lett. , vol.148 , pp. 137-140
    • Megyeri, P.1    Abraham, C.S.2    Temesvari, P.3    Kovacs, J.4    Vas, T.5    Speer, C.P.6
  • 36
    • 0018604765 scopus 로고
    • Pentoxifylline-a biomedical profile
    • Muller, R. 1979. Pentoxifylline-a biomedical profile. J. Med. 10: 307-329.
    • (1979) J. Med. , vol.10 , pp. 307-329
    • Muller, R.1
  • 39
    • 0028820014 scopus 로고
    • Effect of interleukin-4 and interleukin-10 on leucocyte migration and nitric oxide production in the mouse
    • Perretti, M., C. Szabo, and C. Thiemermann. 1995. Effect of interleukin-4 and interleukin-10 on leucocyte migration and nitric oxide production in the mouse. Br. J. Pharmacol. 116: 2251-2257.
    • (1995) Br. J. Pharmacol. , vol.116 , pp. 2251-2257
    • Perretti, M.1    Szabo, C.2    Thiemermann, C.3
  • 40
    • 0026743059 scopus 로고
    • Macrophage-induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines
    • Piani, D., M. Spranger, K. Frei, A. Schaffner, and A. Fontana. 1992. Macrophage-induced cytotoxicity of N-methyl-D-aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokines. Eur. J. Immunol. 22: 2429-2436.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2429-2436
    • Piani, D.1    Spranger, M.2    Frei, K.3    Schaffner, A.4    Fontana, A.5
  • 42
    • 0028973084 scopus 로고
    • Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: An expanded therapeutic window
    • Rosenberg, G. A., E. Y. Estrada, J. E. Dencoff, and W. G. Stetler-Stevenson. 1995. Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: An expanded therapeutic window. Brain Res. 703: 151-155.
    • (1995) Brain Res. , vol.703 , pp. 151-155
    • Rosenberg, G.A.1    Estrada, E.Y.2    Dencoff, J.E.3    Stetler-Stevenson, W.G.4
  • 43
  • 44
    • 0028942737 scopus 로고
    • Interleukin-10 differentially regulates cytokine inhibitor and chemokine release from blood mononuclear cells and fibroblasts
    • Seitz, M., P. Loetscher, B. Dewald, H. Towbin, H. Gallati, and M. Baggiolini. 1995. Interleukin-10 differentially regulates cytokine inhibitor and chemokine release from blood mononuclear cells and fibroblasts. Eur. J. Immunol. 25(4): 1129-1132.
    • (1995) Eur. J. Immunol. , vol.25 , Issue.4 , pp. 1129-1132
    • Seitz, M.1    Loetscher, P.2    Dewald, B.3    Towbin, H.4    Gallati, H.5    Baggiolini, M.6
  • 45
    • 0029926093 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor alpha (TNFalpha) activity in rat brain is associated with cerebroprotection after closed head injury
    • Shohami, E., R. Bass, D. Wallach, A. Yamin, and R. Gallily. 1996. Inhibition of tumor necrosis factor alpha (TNFalpha) activity in rat brain is associated with cerebroprotection after closed head injury. J. Cereb. Blood Flow Metab. 16: 378-384.
    • (1996) J. Cereb. Blood Flow Metab. , vol.16 , pp. 378-384
    • Shohami, E.1    Bass, R.2    Wallach, D.3    Yamin, A.4    Gallily, R.5
  • 46
    • 0031047431 scopus 로고    scopus 로고
    • Cytokine production in the brain following closed head injury: Dexanabinol (HU-211) is a novel TNF-α inhibitor and an effective neuroprotectant
    • Shohami, E., R. Gallily, R. Mechoulam, R. Bass, and T. Ben-Hur. 1997. Cytokine production in the brain following closed head injury: Dexanabinol (HU-211) is a novel TNF-α inhibitor and an effective neuroprotectant. J. Neuroimmunol. 72: 169-177.
    • (1997) J. Neuroimmunol. , vol.72 , pp. 169-177
    • Shohami, E.1    Gallily, R.2    Mechoulam, R.3    Bass, R.4    Ben-Hur, T.5
  • 48
    • 0029620361 scopus 로고
    • Inflammatory leukocytic recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury
    • Soares, H. D., R. R. Hicks, D. Smith, and T. K. McIntosh. 1995. Inflammatory leukocytic recruitment and diffuse neuronal degeneration are separate pathological processes resulting from traumatic brain injury. J. Neurosci. 15: 8223-8233.
    • (1995) J. Neurosci. , vol.15 , pp. 8223-8233
    • Soares, H.D.1    Hicks, R.R.2    Smith, D.3    McIntosh, T.K.4
  • 49
    • 0027400847 scopus 로고
    • Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre- And post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand
    • Taupin, V., S. Toulmond, A. Serrano, J. Benavides, and F. Zavala. 1993. Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand. J. Neuroimmunol. 42:177-186.
    • (1993) J. Neuroimmunol. , vol.42 , pp. 177-186
    • Taupin, V.1    Toulmond, S.2    Serrano, A.3    Benavides, J.4    Zavala, F.5
  • 50
    • 0028982742 scopus 로고
    • Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat
    • Toulmond, S., and N. J. Rothwell. 1995. Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat. Brain Res. 671: 261-266.
    • (1995) Brain Res. , vol.671 , pp. 261-266
    • Toulmond, S.1    Rothwell, N.J.2
  • 51
    • 0029890689 scopus 로고    scopus 로고
    • The contrasting roles of ICE family proteases and interleukin-1 beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation
    • Troy, C. M., L. Stefanis, A. Prochiantz, L. A. Greene, and M. L. Shelanski. 1996. The contrasting roles of ICE family proteases and interleukin-1 beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation. Proc. Natl. Acad. Sci. USA 93(11): 5635-5640.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , Issue.11 , pp. 5635-5640
    • Troy, C.M.1    Stefanis, L.2    Prochiantz, A.3    Greene, L.A.4    Shelanski, M.L.5
  • 52
    • 0028147754 scopus 로고
    • Blood-brain barrier changes following intracerebral injection of human recombinant tumor necrosis factor-alpha in the rat
    • Wright, J. L., and R. E. Merchant. 1994. Blood-brain barrier changes following intracerebral injection of human recombinant tumor necrosis factor-alpha in the rat. J. Neurooncol. 20:17-25.
    • (1994) J. Neurooncol. , vol.20 , pp. 17-25
    • Wright, J.L.1    Merchant, R.E.2
  • 53
    • 0028820478 scopus 로고
    • Molecular strategies in CNS injury
    • Yakovlev, A. G., and A. I. Faden. 1995. Molecular strategies in CNS injury. J. Neurotrauma. 12: 767-777.
    • (1995) J. Neurotrauma. , vol.12 , pp. 767-777
    • Yakovlev, A.G.1    Faden, A.I.2
  • 54
    • 0030804272 scopus 로고    scopus 로고
    • Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury
    • Yakovlev, A. G., S. M. Knoblach, L. Fan, R. Goodnight, and A. I. Faden. 1997. Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. J. Neurosci. 17(19): 7415-7424.
    • (1997) J. Neurosci. , vol.17 , Issue.19 , pp. 7415-7424
    • Yakovlev, A.G.1    Knoblach, S.M.2    Fan, L.3    Goodnight, R.4    Faden, A.I.5
  • 55
    • 0343677157 scopus 로고    scopus 로고
    • Cerebral injection of antiinflammatory cytokine IL-10 increases the size of cerebral infarcts in the rat
    • Abstract
    • Zhai, Q-H., N. Futrell, and F-J. Chen. 1996. Cerebral injection of antiinflammatory cytokine IL-10 increases the size of cerebral infarcts in the rat. Soc. Neurosci. Abs. 22: 5. [Abstract]
    • (1996) Soc. Neurosci. Abs. , vol.22 , pp. 5
    • Zhai, Q.-H.1    Futrell, N.2    Chen, F.-J.3


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