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Volumn 1217, Issue 2, 2010, Pages 199-208
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A new thermodynamic model describes the effects of ligand density and type, salt concentration and protein species in hydrophobic interaction chromatography
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Author keywords
Ligand density; Protein adsorption isotherm; Protein adsorption thermodynamics; Retention model
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Indexed keywords
GLOBULAR PROTEINS;
HYDROPHOBIC INTERACTION CHROMATOGRAPHY;
HYDROPHOBIC INTERFACE;
ISOCRATIC;
LIGAND DENSITY;
LOADING DATA;
PROTEIN ADSORPTION;
PROTEIN RETENTION;
PROTEIN SPECIES;
REPRODUCIBILITIES;
RESPONSE BEHAVIOR;
RETENTION MODELS;
SALT CONCENTRATION;
SOLVENT ACTIVITY;
THERMODYNAMIC MODEL;
WATER DISPLACEMENT;
ADSORPTION;
ADSORPTION ISOTHERMS;
CHROMATOGRAPHIC ANALYSIS;
GEL PERMEATION CHROMATOGRAPHY;
HYDROPHOBIC CHROMATOGRAPHY;
HYDROPHOBICITY;
LIGANDS;
RESINS;
THERMODYNAMIC PROPERTIES;
PROTEINS;
ALPHA LACTALBUMIN;
CARBONATE DEHYDRATASE;
GLOBULAR PROTEIN;
LYSOZYME;
OVALBUMIN;
RESIN;
SODIUM CHLORIDE;
ADSORPTION;
ARTICLE;
CHROMATOGRAPHY;
CONCENTRATION (PARAMETERS);
CONTROLLED STUDY;
DENSITY;
HYDROPHOBICITY;
ISOCRATIC ELUTION CHROMATOGRAPHY;
ISOTHERMAL TITRATION CALORIMETRY;
LIGAND BINDING;
LOADING TEST;
NONHUMAN;
PRIORITY JOURNAL;
REPRODUCIBILITY;
SOLVENT EFFECT;
THERMODYNAMICS;
ADSORPTION;
ALGORITHMS;
CHROMATOGRAPHY, LIQUID;
HYDROPHOBICITY;
LIGANDS;
MODELS, CHEMICAL;
PROTEINS;
REPRODUCIBILITY OF RESULTS;
SEPHAROSE;
THERMODYNAMICS;
WATER;
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EID: 72449208847
PISSN: 00219673
EISSN: None
Source Type: Journal
DOI: 10.1016/j.chroma.2009.07.068 Document Type: Article |
Times cited : (46)
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References (52)
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