Modeling of protein monomer/aggregate purification and separation using hydrophobic interaction chromatography

Bioprocess and Biosystems Engineering

Volumn 31, Issue 3, 2008, Pages 261-275

  McCue, Justin T ^a   Engel, Philip ^a   Ng, Austen ^a   Macniven, Rich ^a   Thömmes, Jörg ^a  

^a BIOGEN   (United States)

Author keywords

Diffusivity; Hydrophobic interaction chromatography; Irreversible binding; Preparative chromatography

Indexed keywords

HYDROPHOBIC INTERACTION CHROMATOGRAPHY; LANGMUIR BINARY ISOTHERM;

AGGLOMERATION; DESORPTION; HYDROPHOBIC CHROMATOGRAPHY; LANGMUIR BLODGETT FILMS; MONOMERS;

PROTEINS;

MONOMER; PHENYLSEPHAROSE; SEPHAROSE; UNCLASSIFIED DRUG;

ADSORPTION; ARTICLE; CHROMATOGRAPHY; DESORPTION; DIFFUSION; EXPERIMENTAL STUDY; PREDICTION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PURIFICATION; SEPARATION TECHNIQUE;

ADSORPTION; ALGORITHMS; BINDING, COMPETITIVE; BIOTECHNOLOGY; CHROMATOGRAPHY; DIFFUSION; HYDROPHOBICITY; MACROMOLECULAR SUBSTANCES; MODELS, CHEMICAL; MODELS, THEORETICAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS; SEPHAROSE; SOLVENTS;

EID: 41049112488     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-008-0200-1     Document Type: Article

References (55)

1. Shepard CC, Tiseliu A (1949) Discussion of the Faraday society. Hazell Watson and Winey, London, p 275
2. Hearn MT (2000) In: Ahuja S (ed) Handbook of bioseparation. Academic Press, New York, pp 71-235
3. Queiroz JA, Tomaz CT, Cabral JMS (2001) Hydrophobic interaction chromatography of proteins. J Biotechnol 87:143
4. Boschetti E, Jungbauer A (2000) In: Ahuja S (ed) Handbook of bioseparation. Academic Press, New York, pp 535-632
5. Halperin G, Breitenbach M, Tauber-Finkelstein M, Shaltiel S (1981) Hydrophobic chromatography on homologous series of alkylagaroses: A comparison of charged and electrically neutral column materials. J Chromatogr 215:211
6. Hjerten S, Mohammed J, Eriksson KO, Liao JL (1991) General methods to render macroporous stationary phases nonporous and deformable, exemplified with agarose and silica beads and their use in high-performance ion-exchange and hydrophobic-interaction chromatography of proteins. Chromatographia 31:85
7. Jennissen HP, Demiroglou A (1992) Base-atom recognition in protein adsorption to alkyl agaroses. J Chromatogr 597:93
8. Schwart W, Judd D, Wysocki M, Guerrier L, Birck-Wilson E, Boschetti E (2001) Comparison of hydrophobic charge induction chromatography with affinity chromatography on protein A for harvest and purification of antibodies. J Chromatogr A 908:251
9. Hearn MTW (2002) In: Gooding KM, Regnier FE (eds) HPLC of Biological macromolecules. Marcel Dekker, New York, p 99
10. Jungbauer A, Feng W (2002) In: Gooding KM, Regnier FE (eds) HPLC of biological macromolecules. Marcel Dekker, New York, pp 281-373
11. Pahlman S, Rosengren J, Hjerten S (1977) Hydrophobic interaction chromatography on uncharged sepharose derivatives: effects of neutral salts on the adsorption of proteins. J Chromatogr 131:99
12. Rosengren J, Pahlman S, Glad M, Hjerten S (1975) Hydrophobic interaction chromatography on non-charged Sepharose derivatives. Binding of a model protein, related to ionic strength, hydrophobicity of the substituent, and degree of substitution (determined by NMR). Biochem Biophys Acta 412:51
13. Melander WR, Horvát C (1977) Salt effects on hydrophobic interactions in precipitation and chromatography of proteins: an interpretation of the lyotropic series. Arch Biochem Biophys 183:200
14. Melander WR, Horvát C (1984) Salt-mediated retention of proteins in hydrophobic-interaction chromatography: application of solvophobic theory. J Chromatogr 317:67
15. Wu SL, Figueroa A, Karger BL (1986) Protein conformational effect in hydrophobic interaction chromatography: retention characterization and the role of mobile phase additives and stationary phase hydrophobicity. J Chromatogr 371:3
16. Roettger BF, Myers JA, Ladisch MR, Regnier FE (1989) Adsorption phenomena in hydrophobic interaction chromatography. Biotechnol Prog 5:79
17. Perkins TW, Mak DS, Root TW, Lightfoot EN (1997) Protein retention in hydrophobic interaction chromatography: modeling variation with buffer ionic strength and column hydrophobicity. J Chromatogr A 766:1
18. Xia F, Nagrath D, Cramer SM (2003) Modeling of adsorption in hydrophobic interaction chromatography systems using a preferential interaction quadratic isotherm. J Chromatogr A 989:47
19. Janson J, Rydén L (eds) (1998) Protein purification, 2nd edn. Wiley-VCH Inc., New York, pp 283-296
20. Saito Y, Wada A (1983) Comparative study of GuHCl denaturation of globular proteins. I. Spectroscopic and chromatographic analysis of the denaturation curves of ribonuclease A, cytochrome c, and pepsinogen. Biopolym Pept Sci Sect 22:2105
21. Goheen SC, Engelhorn SC (1984) Hydrophobic interaction high-performance liquid chromatography of proteins. J Chromatogr 317:55
22. Benedek K, Dong S, Karger BL (1984) Kinetics of unfolding of proteins on hydrophobic surfaces in reversed-phase liquid chromatography. J Chromatogr 317:227
23. Wu S-L, Benedek K, Karger BL (1986) Thermal behavior of proteins in high-performance hydrophobic-interaction chromatography On-line spectroscopic and chromatographic characterization. J Chromatogr 359:3
24. Oroszlan P, Blanco R, Lu X-M, Yarmush D, Karger BL (1990) Intrinsic fluorescence studies of the kinetic mechanism of unfolding of α-lactalbumin on weakly hydrophobic chromatographic surfaces. J Chromatogr 500:481
25. Lu XM, Benedek K, Karger BL (1986) Conformational effects in the high-performance liquid chromatography of proteins Further studies of the reversed-phase chromatographic behavior of ribonuclease A. J Chromatogr A 359:19
26. Fausnaugh JL, Kennedy LA, Regnier FE (1997) Comparison of hydrophobic-interaction and reversed-phase chromatography of proteins. J Chromatogr 317:141
27. De Frutos M, Cifuentes A, D'Iez-Masa JC (1997) Multiple peaks in high-performance liquid chromatography of proteins ß-lactoglobulins eluted in a hydrophobic interaction chromatography system. J Chromatogr A 778:43
28. Goheen SC, Gibbins BM (2000) Protein losses in ion-exchange and hydrophobic interaction high-performance liquid chromatography. J Chromatogr A 890:73
29. Karger BL, Blanco R (1989) The effect of on-column structural changes of proteins on their HPLC behavior. Talanta 36:243
30. Goheen SC, Gibbins BM, Hilsenbeck JL, Edwards JV (2001) ACS Symp Ser 792:20
31. McNay JL, Fernandez EJ (1999) How does a protein unfold on a reversed-phase liquid chromatography surface? J Chromatogr A 849:135
32. Buijs J, Costa Vera C, Ayala E, Steensma E, Hakansson P, Oscarsson S (1999) Conformational stability of adsorbed insulin studied with mass spectrometry and hydrogen exchange. Anal Chem 71:3219
33. Tibbs Jones T, Fernandez EJ (2003) Alpha-lactalbumin tertiary structure changes on hydrophobic interaction chromatography surfaces. J Colloid Interface Sci 259:27
34. Jones TT, Fernandez EJ (2004) Hydrophobic interaction chromatography selectivity changes among three stable proteins: conformation does not play a major role. Biotechnol Bioeng 87:388
35. Lundstrom I (1985) Models of protein adsorption on solid surfaces. Prog Colloid Polym Sci 70:76
36. Jungbauer A, Machold C, Hahn R (2005) Hydrophobic interaction chromatography of proteins: III. Unfolding of proteins upon adsorption. J Chromatogr A 1079:221
37. Haimer E, Tscheliessnig A, Hahn R, Jungbauer A (2007) Hydrophobic interaction chromatography of proteins IV: kinetics of protein spreading. J Chromatogr A 1139:84
38. Yang H, Etzel MR (2003) Evaluation of three kinetic equations in models of protein purification using ion-exchange membranes. Ind Eng Chem 42:890
39. Langmuir I (1918) The adsorption of gases on plain surfaces of glass, mica, and platinum. J Am Chem Soc 40:1361
40. Bellot JC, Condoret JS (1993) Modelling of liquid chromatography equilibria. Process Biochem 28:365
41. Ruthven DM (ed) (1984) Principles of adsorption and adsorption processes. Wiley Interscience, New York
42. McKay G, Duri BA (1989) Prediction of multicomponent adsorption equilibrium data using empirical correlations. Chem Eng J 41:9
43. Katti AM, Guiochon G (1988) Prediction of band profiles in displacement chromatography by numerical integration of a semi-ideal model. J Chrom 449:25
44. Katti AM, Guiochon G (1990) Quantitative comparison between the experimental band profiles of binary mixtures in overloaded elution chromatography and their profiles predicted by the semi-ideal model. J Chrom 499:21
45. Phillips MW, Subramanium G, Cramer SM (1988) Theoretical optimization of operating parameters in non-ideal displacement chromatography. J Chrom 454:1
46. Quiñones-Garcia I, Rayner I, Levison PR, Dickson N, Purdom G (2001) Performance Comparison of suspended bed and batch contactor chromatography. J Chromatogr A 908:69
47. McCue JT, Kemp G, Low D, Quiñones-Garcia I (2003) Evaluation of protein-A chromatography media. J Chromatogr A 989:139
48. Weaver LE, Carta G (1996) Protein adsorption on cation exchangers: comparison of macroporous and gel-composite media. Biotechnol Prog 12:342
49. Foo SC, Rice RG (1975) On the prediction of ultimate separation in parametric pumps. AIChEJ 21:1149
50. Deuflhard P (1974) A modified Newton method for the solution of ill-conditioned systems of nonlinear equations with application to multiple shooting. Numer Math 22:289
51. Schenk O, Gärtner K (2002) Two-level scheduling in PARDISO: improved scalability on shared memory multiprocessing systems. Parallel Comput 28:187
52. Schenk O, Gärtner K (2004) Solving unsymmetric sparse systems of linear equations with PARDISO. J Future Generation Comput Syst 20:475
53. Gärtner K, Schenk O, Fichtner W (1999) Parallel multigrid methods for the continuity equations in semiconductor device simulation. Speedup J 12:67
54. COMSOL Multiphysics Command Reference (2006) Version 3.3, p 193
55. Tyn MT, Gusek TW (1990) Prediction of diffusion coefficients of proteins. Biotechnol Bioeng 35:327