Quality by design-Thermodynamic modelling of chromatographic separation of proteins

Journal of Chromatography A

Volumn 1177, Issue 2, 2008, Pages 200-206

  Mollerup, Jørgen M ^a   Hansen, Thomas Budde ^b   Kidal, Steffen ^b   Staby, Arne ^b  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b NOVO NORDISK A S   (Denmark)

Author keywords

Adsorption isotherms; Computer simulation; HIC; Hydrophobic chromatography; IEC; Ion exchange; PAT; Protein purification; Quality by design

Indexed keywords

ADSORPTION ISOTHERMS; COMPUTER SIMULATION; HYDROPHOBIC CHROMATOGRAPHY; ION EXCHANGE; SEPARATION; THERMODYNAMICS;

MULTI-COMPONENT ADSORPTION; PROTEIN PURIFICATION;

PROTEINS;

ADSORPTION; ARTICLE; CHROMATOGRAPHY; COMPUTER SIMULATION; ION EXCHANGE CHROMATOGRAPHY; ISOTHERM; MODEL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PURIFICATION; THERMODYNAMICS;

ADSORPTION; ALGORITHMS; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, ION EXCHANGE; COMPUTER SIMULATION; HYDROPHOBICITY; LIGANDS; MODELS, CHEMICAL; OSMOLAR CONCENTRATION; PROTEINS;

EID: 37349120092     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2007.08.059     Document Type: Article

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