Purification human PON1Q192 and PON1R192 isoenzymes by hydrophobic interaction chromatography and investigation of the inhibition by metals

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 3, 2009, Pages 134-140

  Gençer, Nahit ^a   Arslan, Oktay ^a  

^a BALIKESIR UNIVERSITY   (Turkey)

Author keywords

Hydrophobic interaction chromatography; Inhibition; Metals; Phenotype; PON1; Purification

Indexed keywords

AMINO ACIDS; AMMONIUM COMPOUNDS; BODY FLUIDS; CADMIUM; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; COLLOIDS; COPPER; DIFFUSERS (OPTICAL); ELECTROPHORESIS; ENZYME INHIBITION; ENZYMES; FLOW INTERACTIONS; GEL PERMEATION CHROMATOGRAPHY; GELATION; HEAVY METALS; HYDROPHOBICITY; MANGANESE; MANGANESE COMPOUNDS; MERCURY (METAL); METAL REFINING; METALS; POLYMERS; PURIFICATION;

AMMONIUM SULFATE PRECIPITATIONS; HUMAN SERUMS; HYDROPHOBIC INTERACTION CHROMATOGRAPHY; IN VITRO; INHIBITION; KINETIC CONSTANTS; PARAOXON; PHENOTYPE; POLYACRYLAMIDE GEL ELECTROPHORESES; PON1; PURIFIED ENZYMES; SEPHAROSE; SINGLE BANDS;

HYDROPHOBIC CHROMATOGRAPHY;

ARYLDIALKYLPHOSPHATASE 1; CADMIUM; COPPER; ISOENZYME; MANGANESE; MERCURY; NICKEL; ARYLDIALKYLPHOSPHATASE; ENZYME INHIBITOR; HEAVY METAL; PARAOXON; PON1 PROTEIN, HUMAN;

ARTICLE; CHROMATOGRAPHY; ENZYME PURIFICATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; BLOOD; DRUG ANTAGONISM; GEL CHROMATOGRAPHY; HUMAN; HYDROPHOBICITY; IC 50; KINETICS; METABOLISM;

ARYLDIALKYLPHOSPHATASE; CHROMATOGRAPHY, AGAROSE; ENZYME INHIBITORS; HUMANS; HYDROPHOBICITY; INHIBITORY CONCENTRATION 50; ISOENZYMES; KINETICS; METALS, HEAVY; PARAOXON;

EID: 58149191229     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.11.037     Document Type: Article

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