-
1
-
-
84863645883
-
A human hepatocytes-bearing mouse: A novel animal model to study the mechanism of liver size control in mammals
-
Yoshizato K., Tateno C., Utoh R., A human hepatocytes-bearing mouse: a novel animal model to study the mechanism of liver size control in mammals International Journal of Design Nature 2009 4 2 1 20
-
(2009)
International Journal of Design Nature
, vol.4
, Issue.2
, pp. 1-20
-
-
Yoshizato, K.1
Tateno, C.2
Utoh, R.3
-
2
-
-
85047691361
-
Cytoglobin/STAP, its unique localization in splanchnic fibroblast-like cells and function in organ fibrogenesis
-
Nakatani K., Okuyama H., Shimahara Y., Cytoglobin/STAP, its unique localization in splanchnic fibroblast-like cells and function in organ fibrogenesis Laboratory Investigation 2004 84 1 91 101
-
(2004)
Laboratory Investigation
, vol.84
, Issue.1
, pp. 91-101
-
-
Nakatani, K.1
Okuyama, H.2
Shimahara, Y.3
-
3
-
-
5444247776
-
Liver development update: New embryo models, cell lineage control, and morphogenesis
-
Lemaigre F., Zaret K. S., Liver development update: new embryo models, cell lineage control, and morphogenesis Current Opinion in Genetics Development 2004 14 5 582 590
-
(2004)
Current Opinion in Genetics Development
, vol.14
, Issue.5
, pp. 582-590
-
-
Lemaigre, F.1
Zaret, K.S.2
-
5
-
-
0029071830
-
Complete reconstitution of mouse liver with xenogeneic hepatocytes
-
Rhim J. A., Sandgren E. P., Palmiter R. D., Brinster R. L., Complete reconstitution of mouse liver with xenogeneic hepatocytes Proceedings of the National Academy of Sciences of the United States of America 1995 92 11 4942 4946
-
(1995)
Proceedings of the National Academy of Sciences of the United States of America
, vol.92
, Issue.11
, pp. 4942-4946
-
-
Rhim, J.A.1
Sandgren, E.P.2
Palmiter, R.D.3
Brinster, R.L.4
-
6
-
-
17744378552
-
Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus
-
DOI 10.1053/jhep.2001.23314
-
Dandri M., Burda M. R., Trk E., Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus Hepatology 2001 33 4 981 988 (Pubitemid 32246649)
-
(2001)
Hepatology
, vol.33
, Issue.4
, pp. 981-988
-
-
Dandri, M.1
Burda, M.R.2
Torok, E.3
Polok, J.M.4
Iwanska, A.5
Sommer, G.6
Rogiers, X.7
Rogler, C.E.8
Gupta, S.9
Will, H.10
Greten, H.11
Petersen, J.12
-
7
-
-
17944379233
-
Hepatitis C virus replication in mice with chimeric human livers
-
Mercer D. F., Schiller D. E., Elliott J. F., Hepatitis C virus replication in mice with chimeric human livers Nature Medicine 2001 7 8 927 933
-
(2001)
Nature Medicine
, vol.7
, Issue.8
, pp. 927-933
-
-
Mercer, D.F.1
Schiller, D.E.2
Elliott, J.F.3
-
8
-
-
4344574035
-
Near completely humanized liver in mice shows human-type metabolic responses to drugs
-
Tateno C., Yoshizane Y., Saito N., Near completely humanized liver in mice shows human-type metabolic responses to drugs American Journal of Pathology 2004 165 3 901 912
-
(2004)
American Journal of Pathology
, vol.165
, Issue.3
, pp. 901-912
-
-
Tateno, C.1
Yoshizane, Y.2
Saito, N.3
-
9
-
-
16244415868
-
Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera
-
Meuleman P., Libbrecht L., De Vos R., Morphological and biochemical characterization of a human liver in a uPA-SCID mouse chimera Hepatology 2005 41 4 847 856
-
(2005)
Hepatology
, vol.41
, Issue.4
, pp. 847-856
-
-
Meuleman, P.1
Libbrecht, L.2
De Vos, R.3
-
10
-
-
16244404610
-
Mice with chimeric human livers: Who says supermodels have to be tall?
-
Kneteman N. M., Mercer D. F., Mice with chimeric human livers: who says supermodels have to be tall? Hepatology 2005 41 4 703 706
-
(2005)
Hepatology
, vol.41
, Issue.4
, pp. 703-706
-
-
Kneteman, N.M.1
Mercer, D.F.2
-
11
-
-
21444433072
-
Induction of human CYP1A2 and CYP3A4 in primary culture of hepatocytes from chimeric mice with humanized liver
-
Nishimura M., Yokoi T., Tateno C., Induction of human CYP1A2 and CYP3A4 in primary culture of hepatocytes from chimeric mice with humanized liver Drug Metabolism and Pharmacokinetics 2005 20 2 121 126
-
(2005)
Drug Metabolism and Pharmacokinetics
, vol.20
, Issue.2
, pp. 121-126
-
-
Nishimura, M.1
Yokoi, T.2
Tateno, C.3
-
12
-
-
0025144417
-
Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator
-
Heckel J. L., Sandgren E. P., Degen J. L., Palmiter R. D., Brinster R. L., Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activator Cell 1990 62 3 447 456
-
(1990)
Cell
, vol.62
, Issue.3
, pp. 447-456
-
-
Heckel, J.L.1
Sandgren, E.P.2
Degen, J.L.3
Palmiter, R.D.4
Brinster, R.L.5
-
13
-
-
0025781894
-
Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene
-
Sandgren E. P., Palmiter R. D., Heckel J. L., Daughterly C. C., Brinster R. L., Degen J. L., Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene Cell 1991 66 2 245 256
-
(1991)
Cell
, vol.66
, Issue.2
, pp. 245-256
-
-
Sandgren, E.P.1
Palmiter, R.D.2
Heckel, J.L.3
Daughterly, C.C.4
Brinster, R.L.5
Degen, J.L.6
-
14
-
-
0028353410
-
Replacement of diseased mouse liver by hepatic cell transplantation
-
Rhim J. A., Sandgren E. P., Degen J. L., Palmiter R. D., Brinster R. L., Replacement of diseased mouse liver by hepatic cell transplantation Science 1994 263 5150 1149 1152
-
(1994)
Science
, vol.263
, Issue.5150
, pp. 1149-1152
-
-
Rhim, J.A.1
Sandgren, E.P.2
Degen, J.L.3
Palmiter, R.D.4
Brinster, R.L.5
-
15
-
-
0035816696
-
Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells
-
Kawada N., Kristensen D. B., Asahina K., Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells The Journal of Biological Chemistry 2001 276 27 25318 25323
-
(2001)
The Journal of Biological Chemistry
, vol.276
, Issue.27
, pp. 25318-25323
-
-
Kawada, N.1
Kristensen, D.B.2
Asahina, K.3
-
16
-
-
28744442170
-
Evaluation of mRNA expression of human drug-metabolizing enzymes and transporters in chimeric mouse with humanized liver
-
Nishimura M., Yoshitsugu H., Yokoi T., Evaluation of mRNA expression of human drug-metabolizing enzymes and transporters in chimeric mouse with humanized liver Xenobiotica 2005 35 9 877 890
-
(2005)
Xenobiotica
, vol.35
, Issue.9
, pp. 877-890
-
-
Nishimura, M.1
Yoshitsugu, H.2
Yokoi, T.3
-
18
-
-
35648976075
-
Induction of hepatic cytochrome P450 enzymes: Methods, mechanisms, recommendations, and in vitro-in vivo correlations
-
Hewitt N. J., Lecluyse E. L., Ferguson S. S., Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations Xenobiotica 2007 37 10-11 1196 1224
-
(2007)
Xenobiotica
, vol.37
, Issue.1011
, pp. 1196-1224
-
-
Hewitt, N.J.1
Lecluyse, E.L.2
Ferguson, S.S.3
-
19
-
-
56749175044
-
Induction of drug metabolism: Species differences and toxicological relevance
-
Graham M. J., Lake B. G., Induction of drug metabolism: species differences and toxicological relevance Toxicology 2008 254 3 184 191
-
(2008)
Toxicology
, vol.254
, Issue.3
, pp. 184-191
-
-
Graham, M.J.1
Lake, B.G.2
-
20
-
-
0034454016
-
Determining the best animal model for human cytochrome P450 activities: A comparison of mouse, rat, rabbit, dog, micropig, monkey and man
-
Bogaards J. J. P., Bertrand M., Jackson P., Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man Xenobiotica 2000 30 12 1131 1152
-
(2000)
Xenobiotica
, vol.30
, Issue.12
, pp. 1131-1152
-
-
Bogaards, J.J.P.1
Bertrand, M.2
Jackson, P.3
-
21
-
-
0019719023
-
The current status of attempts to predict species differences in drug metabolism
-
Caldwell J., The current status of attempts to predict species differences in drug metabolism Drug Metabolism Reviews 1981 12 2 221 237
-
(1981)
Drug Metabolism Reviews
, vol.12
, Issue.2
, pp. 221-237
-
-
Caldwell, J.1
-
22
-
-
0742286803
-
Cytochrome P450 2D6: Overview and update on pharmacology, genetics, biochemistry
-
Zanger U. M., Raimundo S., Eichelbaum M., Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry Naunyn-Schmiedebergs Archives of Pharmacology 2004 369 1 23 37
-
(2004)
Naunyn-Schmiedebergs Archives of Pharmacology
, vol.369
, Issue.1
, pp. 23-37
-
-
Zanger, U.M.1
Raimundo, S.2
Eichelbaum, M.3
-
23
-
-
3042515935
-
Polymorphic cytochrome P450, 2D6: Humanized mouse model and endogenous substrates
-
Yu A.-M., Idle J. R., Gonzalez F. J., Polymorphic cytochrome P450, 2D6: humanized mouse model and endogenous substrates Drug Metabolism Reviews 2004 36 2 243 277
-
(2004)
Drug Metabolism Reviews
, vol.36
, Issue.2
, pp. 243-277
-
-
Yu, A.-M.1
Idle, J.R.2
Gonzalez, F.J.3
-
25
-
-
33847034231
-
In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver
-
Katoh M., Sawada T., Soeno Y., In vivo drug metabolism model for human cytochrome P450 enzyme using chimeric mice with humanized liver Journal of Pharmaceutical Sciences 2007 96 2 428 437
-
(2007)
Journal of Pharmaceutical Sciences
, vol.96
, Issue.2
, pp. 428-437
-
-
Katoh, M.1
Sawada, T.2
Soeno, Y.3
-
26
-
-
0033927671
-
Measurement of cytochrome P450 gene induction in human hepatocytes, using quantitative real-time reverse transcriptase-polymerase chain reaction
-
Bowen W. P., Carey J. E., Miah A., Measurement of cytochrome P450 gene induction in human hepatocytes, using quantitative real-time reverse transcriptase-polymerase chain reaction Drug Metabolism and Disposition 2000 28 7 781 788
-
(2000)
Drug Metabolism and Disposition
, vol.28
, Issue.7
, pp. 781-788
-
-
Bowen, W.P.1
Carey, J.E.2
Miah, A.3
-
27
-
-
18844441734
-
In vivo induction of human cytochrome P450 enzymes expressed in chimeric mice with humanized liver
-
DOI 10.1124/dmd.104.002600
-
Katoh M., Matsui T., Nakajima M., In vivo induction of human cytochrome P450 enzymes expressed in chimeric mice with humanized liver Drug Metabolism and Disposition 2005 33 6 754 763 (Pubitemid 40686628)
-
(2005)
Drug Metabolism and Disposition
, vol.33
, Issue.6
, pp. 754-763
-
-
Katoh, M.1
Matsui, T.2
Nakajima, M.3
Tateno, C.4
Soeno, Y.5
Horie, T.6
Iwasaki, K.7
Yoshizato, K.8
Yokoi, T.9
-
28
-
-
62149088599
-
Unveiling a new essential cis element for the transactivation of the CYP3A4 gene by xenobiotics
-
Toriyabe T., Nagata K., Takada T., Unveiling a new essential cis element for the transactivation of the CYP3A4 gene by xenobiotics Molecular Pharmacology 2009 75 3 677 684
-
(2009)
Molecular Pharmacology
, vol.75
, Issue.3
, pp. 677-684
-
-
Toriyabe, T.1
Nagata, K.2
Takada, T.3
-
29
-
-
17744375160
-
The pregnane X receptor: A promiscuous xenobiotic receptor that has diverged during evolution
-
Jones S. A., Moore L. B., Shenk J. L., The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution Molecular Endocrinology 2000 14 1 27 39
-
(2000)
Molecular Endocrinology
, vol.14
, Issue.1
, pp. 27-39
-
-
Jones, S.A.1
Moore, L.B.2
Shenk, J.L.3
-
30
-
-
0242414770
-
Oltipraz inhibits 3-methylcholanthrene induction of CYP1A1 by CCAAT/enhancer-binding protein activation
-
Cho I. J., Kim S. G., Oltipraz inhibits 3-methylcholanthrene induction of CYP1A1 by CCAAT/enhancer-binding protein activation The Journal of Biological Chemistry 2003 278 45 44103 44112
-
(2003)
The Journal of Biological Chemistry
, vol.278
, Issue.45
, pp. 44103-44112
-
-
Cho, I.J.1
Kim, S.G.2
-
31
-
-
10744232330
-
The conduct of in vitro and in vivo drug-drug interaction studies: A Pharmaceutical Research and Manufacturers of America (PhRMA) perspective
-
Bjornsson T. D., Callaghan J. T., Einolf H. J., The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective Drug Metabolism and Disposition 2003 31 7 815 832
-
(2003)
Drug Metabolism and Disposition
, vol.31
, Issue.7
, pp. 815-832
-
-
Bjornsson, T.D.1
Callaghan, J.T.2
Einolf, H.J.3
-
32
-
-
23944453878
-
Expression of human phase II enzymes in chimeric mice with humanized liver
-
Katoh M., Matsui T., Okumura H., Expression of human phase II enzymes in chimeric mice with humanized liver Drug Metabolism and Disposition 2005 33 9 1333 1340
-
(2005)
Drug Metabolism and Disposition
, vol.33
, Issue.9
, pp. 1333-1340
-
-
Katoh, M.1
Matsui, T.2
Okumura, H.3
-
33
-
-
0037386735
-
Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor
-
Xie W., Yeuh M.-F., Radominska-Pandya A., Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor Proceedings of the National Academy of Sciences of the United States of America 2003 100 7 4150 4155
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 4150-4155
-
-
Xie, W.1
Yeuh, M.-F.2
Radominska-Pandya, A.3
-
34
-
-
4444246000
-
Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes
-
Kodama S., Koike C., Negishi M., Yamamoto Y., Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes Molecular and Cellular Biology 2004 24 18 7931 7940
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.18
, pp. 7931-7940
-
-
Kodama, S.1
Koike, C.2
Negishi, M.3
Yamamoto, Y.4
-
35
-
-
0037064177
-
Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR
-
Zhang J., Huang W., Chua S. S., Wei P., Moore D. D., Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR Science 2002 298 5592 422 424
-
(2002)
Science
, vol.298
, Issue.5592
, pp. 422-424
-
-
Zhang, J.1
Huang, W.2
Chua, S.S.3
Wei, P.4
Moore, D.D.5
-
36
-
-
34447568362
-
Humanization of excretory pathway in chimeric mice with humanized liver
-
DOI 10.1093/toxsci/kfm041
-
Okumura H., Katoh M., Sawada T., Humanization of excretory pathway in chimeric mice with humanized liver Toxicological Sciences 2007 97 2 533 538 (Pubitemid 47073867)
-
(2007)
Toxicological Sciences
, vol.97
, Issue.2
, pp. 533-538
-
-
Okumura, H.1
Katoh, M.2
Sawada, T.3
Nakajima, M.4
Soeno, Y.5
Yabuuchi, H.6
Ikeda, T.7
Tateno, C.8
Yoshizato, K.9
Yokoi, T.10
-
37
-
-
0024553343
-
Pharmacokinetics of single-dose cefmetazole following intramuscular administration of cefmetazole sodium to healthy male volunteers
-
Ko H., Novak E., Peters G. R., Pharmacokinetics of single-dose cefmetazole following intramuscular administration of cefmetazole sodium to healthy male volunteers Antimicrobial Agents and Chemotherapy 1989 33 4 508 512
-
(1989)
Antimicrobial Agents and Chemotherapy
, vol.33
, Issue.4
, pp. 508-512
-
-
Ko, H.1
Novak, E.2
Peters, G.R.3
-
38
-
-
0018842885
-
Pharmacokinetics of ceftizoxime in animals after parenteral dosing
-
Murakawa T., Sakamoto H., Fukada S., Pharmacokinetics of ceftizoxime in animals after parenteral dosing Antimicrobial Agents and Chemotherapy 1980 17 2 157 164 (Pubitemid 10128995)
-
(1980)
Antimicrobial Agents and Chemotherapy
, vol.17
, Issue.2
, pp. 157-164
-
-
Murakawa, T.1
Sakamoto, H.2
Fukada, S.3
-
39
-
-
34249908931
-
Bezafibrate induces multidrug-resistance P-glycoprotein 3 expression in cultured human hepatocytes and humanized livers of chimeric mice
-
Shoda J., Okada K., Inada Y., Bezafibrate induces multidrug-resistance P-glycoprotein 3 expression in cultured human hepatocytes and humanized livers of chimeric mice Hepatology Research 2007 37 7 548 556
-
(2007)
Hepatology Research
, vol.37
, Issue.7
, pp. 548-556
-
-
Shoda, J.1
Okada, K.2
Inada, Y.3
-
41
-
-
56349163205
-
The human liver-uPA-SCID mouse: A model for the evaluation of antiviral compounds against HBV and HCV
-
Meuleman P., Leroux-Roels G., The human liver-uPA-SCID mouse: a model for the evaluation of antiviral compounds against HBV and HCV Antiviral Research 2008 80 3 231 238
-
(2008)
Antiviral Research
, vol.80
, Issue.3
, pp. 231-238
-
-
Meuleman, P.1
Leroux-Roels, G.2
-
42
-
-
30944468404
-
Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus
-
Tsuge M., Hiraga N., Takaishi H., Infection of human hepatocyte chimeric mouse with genetically engineered hepatitis B virus Hepatology 2005 42 5 1046 1054
-
(2005)
Hepatology
, vol.42
, Issue.5
, pp. 1046-1054
-
-
Tsuge, M.1
Hiraga, N.2
Takaishi, H.3
-
43
-
-
0033574663
-
A unified nomenclature system for the nuclear receptor superfamily
-
Nuclear Receptors Nomenclature Committee
-
Nuclear Receptors Nomenclature Committee, A unified nomenclature system for the nuclear receptor superfamily Cell 1999 97 2 161 163
-
(1999)
Cell
, vol.97
, Issue.2
, pp. 161-163
-
-
-
44
-
-
34547604561
-
Transcription coactivators for peroxisome proliferator-activated receptors
-
Yu S., Reddy J. K., Transcription coactivators for peroxisome proliferator-activated receptors Biochimica et Biophysica Acta 2007 1771 8 936 951
-
(2007)
Biochimica et Biophysica Acta
, vol.1771
, Issue.8
, pp. 936-951
-
-
Yu, S.1
Reddy, J.K.2
-
45
-
-
33751533892
-
International union of pharmacology. LXI. Peroxisome proliferator- activated receptors
-
Michalik L., Auwerx J., Berger J. P., International union of pharmacology. LXI. Peroxisome proliferator-activated receptors Pharmacological Reviews 2006 58 4 726 741
-
(2006)
Pharmacological Reviews
, vol.58
, Issue.4
, pp. 726-741
-
-
Michalik, L.1
Auwerx, J.2
Berger, J.P.3
-
47
-
-
0024599877
-
Differential induction and regulation of peroxisomal enzyme: Predictive value of peroxisome proliferation in identifying certain nonmutagenic carcinogens
-
Nemali M. R., Reddy M. K., Usuda N., Differential induction and regulation of peroxisomal enzyme: predictive value of peroxisome proliferation in identifying certain nonmutagenic carcinogens Toxicology and Applied Pharmacology 1989 97 1 72 87
-
(1989)
Toxicology and Applied Pharmacology
, vol.97
, Issue.1
, pp. 72-87
-
-
Nemali, M.R.1
Reddy, M.K.2
Usuda, N.3
-
48
-
-
46149139817
-
Peroxisome proliterators and cancer: Mechanisms and implications
-
Reddy J. K., Rao M. S., Peroxisome proliterators and cancer: mechanisms and implications Trends in Pharmacological Sciences 1986 7 438 443
-
(1986)
Trends in Pharmacological Sciences
, vol.7
, pp. 438-443
-
-
Reddy, J.K.1
Rao, M.S.2
-
49
-
-
0021060535
-
Detection of a nafenopin binding protein in rat liver cytosol associated with the induction of peroxisome proliferation by hypolipidemic compounds
-
Lalwani N. D., Fahl W. E., Reddy J. K., Detection of a nafenopin binding protein in rat liver cytosol associated with the induction of peroxisome proliferation by hypolipidemic compounds Biochemical and Biophysical Research Communications 1983 116 2 388 393
-
(1983)
Biochemical and Biophysical Research Communications
, vol.116
, Issue.2
, pp. 388-393
-
-
Lalwani, N.D.1
Fahl, W.E.2
Reddy, J.K.3
-
51
-
-
0025132245
-
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
-
Issemann I., Green S., Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators Nature 1990 347 6294 645 650
-
(1990)
Nature
, vol.347
, Issue.6294
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
52
-
-
0026517010
-
Control of the peroxisomal -oxidation pathway by a novel family of nuclear hormone receptors
-
Dreyer C., Krey G., Keller H., Givel F., Helftenbein G., Wahli W., Control of the peroxisomal -oxidation pathway by a novel family of nuclear hormone receptors Cell 1992 68 5 879 887
-
(1992)
Cell
, vol.68
, Issue.5
, pp. 879-887
-
-
Dreyer, C.1
Krey, G.2
Keller, H.3
Givel, F.4
Helftenbein, G.5
Wahli, W.6
-
53
-
-
47349085139
-
The role of PPARs in cancer
-
Tachibana K., Yamasaki D., Ishimoto K., Doi T., The role of PPARs in cancer PPAR Research 2008 2008 15
-
(2008)
PPAR Research
, vol.2008
, pp. 15
-
-
Tachibana, K.1
Yamasaki, D.2
Ishimoto, K.3
Doi, T.4
-
54
-
-
33646180263
-
Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor to Wy-14,643-induced liver tumorigenesis
-
Morimura K., Cheung C., Ward J. M., Reddy J. K., Gonzalez F. J., Differential susceptibility of mice humanized for peroxisome proliferator-activated receptor to Wy-14,643-induced liver tumorigenesis Carcinogenesis 2006 27 5 1074 1080
-
(2006)
Carcinogenesis
, vol.27
, Issue.5
, pp. 1074-1080
-
-
Morimura, K.1
Cheung, C.2
Ward, J.M.3
Reddy, J.K.4
Gonzalez, F.J.5
-
55
-
-
0027763648
-
Hepatic peroxisome proliferation in rodents and its significance for humans
-
Bentley P., Calder I., Elcombe C., Grasso P., Stringer D., Wiegand H.-J., Hepatic peroxisome proliferation in rodents and its significance for humans Food and Chemical Toxicology 1993 31 11 857 907
-
(1993)
Food and Chemical Toxicology
, vol.31
, Issue.11
, pp. 857-907
-
-
Bentley, P.1
Calder, I.2
Elcombe, C.3
Grasso, P.4
Stringer, D.5
Wiegand, H.-J.6
-
56
-
-
0032941350
-
Peroxisome proliferator-activated receptor alpha: Role in rodent liver cancer and species differences
-
Holden P. R., Tugwood J. D., Peroxisome proliferator-activated receptor alpha: role in rodent liver cancer and species differences Journal of Molecular Endocrinology 1999 22 1 1 8
-
(1999)
Journal of Molecular Endocrinology
, vol.22
, Issue.1
, pp. 1-8
-
-
Holden, P.R.1
Tugwood, J.D.2
-
57
-
-
0031952238
-
Peroxisome proliferator activated receptor- expression in human liver
-
Palmer C. N. A., Hsu M.-H., Griffin K. J., Raucy J. L., Johnson E. F., Peroxisome proliferator activated receptor- expression in human liver Molecular Pharmacology 1998 53 1 14 22
-
(1998)
Molecular Pharmacology
, vol.53
, Issue.1
, pp. 14-22
-
-
Palmer, C.N.A.1
Hsu, M.-H.2
Griffin, K.J.3
Raucy, J.L.4
Johnson, E.F.5
-
58
-
-
0026541591
-
The mouse peroxisome proliferator activated receptor recognizes a response element in the 5 ′ flanking sequence of the rat acyl CoA oxidase gene
-
Tugwood J. D., Issemann I., Anderson R. G., Bundell K. R., McPheat W. L., Green S., The mouse peroxisome proliferator activated receptor recognizes a response element in the 5 ′ flanking sequence of the rat acyl CoA oxidase gene The EMBO Journal 1992 11 2 433 439
-
(1992)
The EMBO Journal
, vol.11
, Issue.2
, pp. 433-439
-
-
Tugwood, J.D.1
Issemann, I.2
Anderson, R.G.3
Bundell, K.R.4
McPheat, W.L.5
Green, S.6
-
59
-
-
0026756096
-
Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase
-
Zhang B., Marcus S. L., Saijadi F. G., Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase Proceedings of the National Academy of Sciences of the United States of America 1992 89 16 7541 7545
-
(1992)
Proceedings of the National Academy of Sciences of the United States of America
, vol.89
, Issue.16
, pp. 7541-7545
-
-
Zhang, B.1
Marcus, S.L.2
Saijadi, F.G.3
-
60
-
-
0027161015
-
PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene
-
Bardot O., Aldridge T. C., Latruffe N., Green S., PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene Biochemical and Biophysical Research Communications 1993 192 1 37 45
-
(1993)
Biochemical and Biophysical Research Communications
, vol.192
, Issue.1
, pp. 37-45
-
-
Bardot, O.1
Aldridge, T.C.2
Latruffe, N.3
Green, S.4
-
61
-
-
0028953133
-
Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription
-
Aldridge T. C., Tugwood J. D., Green S., Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription Biochemical Journal 1995 306, part 2 473 479
-
(1995)
Biochemical Journal
, vol.3062
, pp. 473-479
-
-
Aldridge, T.C.1
Tugwood, J.D.2
Green, S.3
-
62
-
-
0029791412
-
PPAR and PPAR activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
-
Schoonjans K., Peinado-Onsurbe J., Lefebvre A.-M., PPAR and PPAR activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene The EMBO Journal 1996 15 19 5336 5348
-
(1996)
The EMBO Journal
, vol.15
, Issue.19
, pp. 5336-5348
-
-
Schoonjans, K.1
Peinado-Onsurbe, J.2
Lefebvre, A.-M.3
-
63
-
-
0030766476
-
Alterations in lipoprotein metabolism in peroxisome proliferator- activated receptor -deficient mice
-
Peters J. M., Hennuyer N., Staels B., Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor -deficient mice The Journal of Biological Chemistry 1997 272 43 27307 27312
-
(1997)
The Journal of Biological Chemistry
, vol.272
, Issue.43
, pp. 27307-27312
-
-
Peters, J.M.1
Hennuyer, N.2
Staels, B.3
-
64
-
-
2542635631
-
Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor
-
Cheung C., Akiyama T. E., Ward J. M., Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor Cancer Research 2004 64 11 3849 3854
-
(2004)
Cancer Research
, vol.64
, Issue.11
, pp. 3849-3854
-
-
Cheung, C.1
Akiyama, T.E.2
Ward, J.M.3
-
65
-
-
0028997684
-
Targeted disruption of the isoform of the peroxisome proliferator- activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
-
Lee S. S., Pineau T., Drago J., Targeted disruption of the isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators Molecular and Cellular Biology 1995 15 6 3012 3022
-
(1995)
Molecular and Cellular Biology
, vol.15
, Issue.6
, pp. 3012-3022
-
-
Lee, S.S.1
Pineau, T.2
Drago, J.3
-
66
-
-
0037900979
-
Lipid metabolism, metabolic diseases, and peroxisome proliferator- activated receptors
-
Lee C.-H., Olson P., Evans R. M., Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors Endocrinology 2003 144 6 2201 2207
-
(2003)
Endocrinology
, vol.144
, Issue.6
, pp. 2201-2207
-
-
Lee, C.-H.1
Olson, P.2
Evans, R.M.3
-
67
-
-
0027363563
-
Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
-
Smit J. J. M., Schinkel A. H., Oude Elferink R. P. J., Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease Cell 1993 75 3 451 462
-
(1993)
Cell
, vol.75
, Issue.3
, pp. 451-462
-
-
Smit, J.J.M.1
Schinkel, A.H.2
Oude Elferink, R.P.J.3
-
68
-
-
0031879556
-
Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice
-
Smith A. J., de Vree J. M. L., Ottenhoff R., Oude Elferink R. P. J., Schinkel A. H., Borst P., Hepatocyte-specific expression of the human MDR3 P-glycoprotein gene restores the biliary phosphatidylcholine excretion absent in Mdr2 (-/-) mice Hepatology 1998 28 2 530 536
-
(1998)
Hepatology
, vol.28
, Issue.2
, pp. 530-536
-
-
Smith, A.J.1
De Vree, J.M.L.2
Ottenhoff, R.3
Oude Elferink, R.P.J.4
Schinkel, A.H.5
Borst, P.6
-
69
-
-
0041665024
-
ABCB4 gene mutation-associated cholelithiasis in adults
-
Rosmorduc O., Hermelin B., Boelle P.-Y., Parc R., Taboury J., Poupon R., ABCB4 gene mutation-associated cholelithiasis in adults Gastroenterology 2003 125 2 452 459
-
(2003)
Gastroenterology
, vol.125
, Issue.2
, pp. 452-459
-
-
Rosmorduc, O.1
Hermelin, B.2
Boelle, P.-Y.3
Parc, R.4
Taboury, J.5
Poupon, R.6
-
70
-
-
0037325403
-
Peroxisome proliferator-activated receptor (PPAR )-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice
-
Kok T., Bloks V. W., Wolters H., Peroxisome proliferator-activated receptor (PPAR )-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice Biochemical Journal 2003 369, part 3 539 547
-
(2003)
Biochemical Journal
, vol.3693
, pp. 539-547
-
-
Kok, T.1
Bloks, V.W.2
Wolters, H.3
-
71
-
-
0029922002
-
Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse
-
Chianale J., Vollrath V., Wielandt A. M., Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse Biochemical Journal 1996 314, part 3 781 786
-
(1996)
Biochemical Journal
, vol.3143
, pp. 781-786
-
-
Chianale, J.1
Vollrath, V.2
Wielandt, A.M.3
-
72
-
-
0033792659
-
Bezafibrate in the treatment of primary biliary cirrhosis: Comparison with ursodeoxycholic acid
-
Kurihara T., Niimi A., Maeda A., Shigemoto M., Yamashita K., Bezafibrate in the treatment of primary biliary cirrhosis: comparison with ursodeoxycholic acid American Journal of Gastroenterology 2000 95 10 2990 2992
-
(2000)
American Journal of Gastroenterology
, vol.95
, Issue.10
, pp. 2990-2992
-
-
Kurihara, T.1
Niimi, A.2
Maeda, A.3
Shigemoto, M.4
Yamashita, K.5
-
73
-
-
0030985318
-
Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
-
Krey G., Braissant O., LHorset F., Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay Molecular Endocrinology 1997 11 6 779 791
-
(1997)
Molecular Endocrinology
, vol.11
, Issue.6
, pp. 779-791
-
-
Krey, G.1
Braissant, O.2
Lhorset, F.3
-
74
-
-
17344390044
-
Fibrate and statin synergistically increase the transcriptional activities of PPAR /RXR and decrease the transactivation of NF B
-
Inoue I., Itoh F., Aoyagi S., Fibrate and statin synergistically increase the transcriptional activities of PPAR /RXR and decrease the transactivation of NF B Biochemical and Biophysical Research Communications 2002 290 1 131 139
-
(2002)
Biochemical and Biophysical Research Communications
, vol.290
, Issue.1
, pp. 131-139
-
-
Inoue, I.1
Itoh, F.2
Aoyagi, S.3
-
75
-
-
16644368576
-
Bezafibrate stimulates canalicular localization of NBD-labeled PC in HepG2 cells by PPAR -mediated redistribution of ABCB4
-
Shoda J., Inada Y., Tsuji A., Bezafibrate stimulates canalicular localization of NBD-labeled PC in HepG2 cells by PPAR -mediated redistribution of ABCB4 Journal of Lipid Research 2004 45 10 1813 1825
-
(2004)
Journal of Lipid Research
, vol.45
, Issue.10
, pp. 1813-1825
-
-
Shoda, J.1
Inada, Y.2
Tsuji, A.3
-
76
-
-
34748870772
-
GH enhances proliferation of human hepatocytes grafted into immunodeficient mice with damaged liver
-
Masumoto N., Tateno C., Tachibana A., GH enhances proliferation of human hepatocytes grafted into immunodeficient mice with damaged liver Journal of Endocrinology 2007 194 3 529 537
-
(2007)
Journal of Endocrinology
, vol.194
, Issue.3
, pp. 529-537
-
-
Masumoto, N.1
Tateno, C.2
Tachibana, A.3
|