Humanization of excretory pathway in chimeric mice with humanized liver

Toxicological Sciences

Volumn 97, Issue 2, 2007, Pages 533-538

  Okumura, Hirotoshi ^a   Katoh, Miki ^a   Sawada, Toshiro ^a   Nakajima, Miki ^a   Soeno, Yoshinori ^b   Yabuuchi, Hikaru ^c   Ikeda, Toshihiko ^d   Tateno, Chise ^e   Yoshizato, Katsutoshi ^e,f   Yokoi, Tsuyoshi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b PhoenixBio USA Corporation   (Japan)

^c GenoMembrane Inc   (Japan)

^d DAIICHI SANKYO CO   (Japan)

^e Hiroshima Prefectural Institute of Industrial Science and Technology   (Japan)

^f HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Biliary excretion; CMZ; Renal excretion; Transporter

Indexed keywords

CEFMETAZOLE; MESSENGER RNA; UROKINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIARY EXCRETION; CHIMERA; CONTROLLED STUDY; DRUG EXCRETION; DRUG METABOLISM; DRUG TRANSPORT; FECES ANALYSIS; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; SCID MOUSE; URINALYSIS; URINARY EXCRETION;

ANIMALS; ANTI-BACTERIAL AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; CEFMETAZOLE; FECES; HEPATITIS, TOXIC; HEPATOCYTES; HUMANS; LIVER; MICE; MICE, INBRED ICR; MICE, SCID; MICE, TRANSGENIC; PHARMACEUTICAL PREPARATIONS; RNA, MESSENGER; URINARY PLASMINOGEN ACTIVATOR;

ANIMALIA; MUS;

EID: 34447568362     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm041     Document Type: Article

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