-
1
-
-
0344541105
-
Molecular mechanisms of cholestasis: Causes and consequences of impaired bile formation
-
Koopen, N. R., Müller, M., Vonk, R. J., Zimniak, P. and Kuipers, F. (1998) Molecular mechanisms of cholestasis: causes and consequences of impaired bile formation. Biochim. Biophys. Acta 1408, 1-17
-
(1998)
Biochim. Biophys. Acta
, vol.1408
, pp. 1-17
-
-
Koopen, N.R.1
Müller, M.2
Vonk, R.J.3
Zimniak, P.4
Kuipers, F.5
-
2
-
-
0032540277
-
The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver
-
Gerloff, T., Stieger, B., Hagenbuch, B., Madon, J., Landmann, L., Roth, J., Hofmann, A. F. and Meier, P. J. (1998) The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver. J. Biol. Chem. 273, 10046-10050
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10046-10050
-
-
Gerloff, T.1
Stieger, B.2
Hagenbuch, B.3
Madon, J.4
Landmann, L.5
Roth, J.6
Hofmann, A.F.7
Meier, P.J.8
-
3
-
-
0029981430
-
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
-
Paulusma, C. C., Bosma, P. J., Zaman, G. J., Bakker, C. T., Otter, M., Scheffer, G. L., Scheper, R. J., Borst, P. and Oude Elferink, R. P. (1996) Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Science 271, 1126-1128
-
(1996)
Science
, vol.271
, pp. 1126-1128
-
-
Paulusma, C.C.1
Bosma, P.J.2
Zaman, G.J.3
Bakker, C.T.4
Otter, M.5
Scheffer, G.L.6
Scheper, R.J.7
Borst, P.8
Oude Elferink, R.P.9
-
4
-
-
0028907388
-
New insights into the mechanism of bile acid-induced biliary lipid secretion
-
Verkade, H. J., Vonk, R. J. and Kuipers, F. (1995) New insights into the mechanism of bile acid-induced biliary lipid secretion. Hepatology 21, 1174-1189
-
(1995)
Hepatology
, vol.21
, pp. 1174-1189
-
-
Verkade, H.J.1
Vonk, R.J.2
Kuipers, F.3
-
5
-
-
0027363563
-
Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
-
Smit, J. J., Schinkel, A. H., Oude Elferink, R. P., Groen, A. K., Wagenaar, E., van Deemter, L., Mol, C. A., Ottenhoff, R., van der Lugt, N. M. and van Roon, M. A. (1993) Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease. Cell 75, 451-462
-
(1993)
Cell
, vol.75
, pp. 451-462
-
-
Smit, J.J.1
Schinkel, A.H.2
Oude Elferink, R.P.3
Groen, A.K.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.7
Ottenhoff, R.8
Van Der Lugt, N.M.9
Van Roon, M.A.10
-
6
-
-
0034958770
-
ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice
-
Vaisman, B. L., Lambert, G., Amar, M., Joyce, C., Ito, T., Shamburek, R. D., Cain, W. J., Fruchart-Najib, J., Neufeld, E. D., Remaley, A. T. et al. (2001) ABCA1 overexpression leads to hyperalphalipoproteinemia and increased biliary cholesterol excretion in transgenic mice. J. Clin. Invest. 108, 303-309
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 303-309
-
-
Vaisman, B.L.1
Lambert, G.2
Amar, M.3
Joyce, C.4
Ito, T.5
Shamburek, R.D.6
Cain, W.J.7
Fruchart-Najib, J.8
Neufeld, E.D.9
Remaley, A.T.10
-
7
-
-
0036733630
-
Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol
-
Yu, L., Li-Hawkins, J., Hammer, R. E., Berge, K. E., Horton, J. D., Cohen, J. C. and Hobbs, H. H. (2002) Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol. J. Clin. Invest. 110, 671-680
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 671-680
-
-
Yu, L.1
Li-Hawkins, J.2
Hammer, R.E.3
Berge, K.E.4
Horton, J.D.5
Cohen, J.C.6
Hobbs, H.H.7
-
8
-
-
0028844806
-
Regulation and function of the multidrug resistance genes in liver
-
Silverman, J. A. and Thorgeirsson, S. S. (1995) Regulation and function of the multidrug resistance genes in liver. Progr. Liver Dis. 13, 101-123
-
(1995)
Progr. Liver Dis.
, vol.13
, pp. 101-123
-
-
Silverman, J.A.1
Thorgeirsson, S.S.2
-
9
-
-
0033736448
-
Hepatic transport of bile salts
-
Kullak-Ublick, G. A., Stieger, B., Hagenbuch, B. and Meier, P. J. (2000) Hepatic transport of bile salts. Semin. Liver Dis. 20, 273-292
-
(2000)
Semin. Liver Dis.
, vol.20
, pp. 273-292
-
-
Kullak-Ublick, G.A.1
Stieger, B.2
Hagenbuch, B.3
Meier, P.J.4
-
10
-
-
0035800772
-
Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor
-
Ananthanarayanan, M., Balasubramanian, N., Makishima, M., Mangelsdorf, D. J. and Suchy, F. J. (2001) Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor. J. Biol. Chem. 276, 28857-28865
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28857-28865
-
-
Ananthanarayanan, M.1
Balasubramanian, N.2
Makishima, M.3
Mangelsdorf, D.J.4
Suchy, F.J.5
-
11
-
-
0034950514
-
The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp
-
Denson, L. A., Sturm, E., Echevarria, W., Zimmerman, T. L., Makishima, M., Mangelsdorf, D. J. and Karpen, S. J. (2001) The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp. Gastroenterology 121, 140-147
-
(2001)
Gastroenterology
, vol.121
, pp. 140-147
-
-
Denson, L.A.1
Sturm, E.2
Echevarria, W.3
Zimmerman, T.L.4
Makishima, M.5
Mangelsdorf, D.J.6
Karpen, S.J.7
-
12
-
-
0037169551
-
Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor
-
Kast, H. R., Goodwin, B., Tarr, P. T., Jones, S. A., Anisfeld, A. M., Stoltz, C. M., Tontonoz, P., Kliewer, S., Willson, T. M. and Edwards, P. A. (2002) Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor. J. Biol. Chem. 277, 2908-2915
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2908-2915
-
-
Kast, H.R.1
Goodwin, B.2
Tarr, P.T.3
Jones, S.A.4
Anisfeld, A.M.5
Stoltz, C.M.6
Tontonoz, P.7
Kliewer, S.8
Willson, T.M.9
Edwards, P.A.10
-
13
-
-
0035976638
-
Nuclear receptors and lipid physiology: Opening the X-files
-
Chawla, A., Repa, J. J., Evans, R. M. and Mangelsdorf, D. J. (2001) Nuclear receptors and lipid physiology: opening the X-files. Science 294, 1866-1870
-
(2001)
Science
, vol.294
, pp. 1866-1870
-
-
Chawla, A.1
Repa, J.J.2
Evans, R.M.3
Mangelsdorf, D.J.4
-
14
-
-
0037166261
-
Regulation of ATP-binding cassette sterol transporters, ABCG5 and ABCG8, by the oxysterol receptors, LXRα and β
-
Repa, J. J., Berge, K. E., Pomajzl, C., Richardson, J. A., Hobbs, H. H. and Mangelsdorf, D. J. (2002) Regulation of ATP-binding cassette sterol transporters, ABCG5 and ABCG8, by the oxysterol receptors, LXRα and β. J. Biol. Chem. 277, 18793-18800
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18793-18800
-
-
Repa, J.J.1
Berge, K.E.2
Pomajzl, C.3
Richardson, J.A.4
Hobbs, H.H.5
Mangelsdorf, D.J.6
-
15
-
-
0033036103
-
Regulation of hepatic transport systems involved in bile secretion during liver regeneration in rats
-
Vos, T. A., Ros, J. E., Havinga, R., Moshage, H., Kuipers, F., Jansen, P. L. and Müller, M. (1999) Regulation of hepatic transport systems involved in bile secretion during liver regeneration in rats. Hepatology 29, 1833-1839
-
(1999)
Hepatology
, vol.29
, pp. 1833-1839
-
-
Vos, T.A.1
Ros, J.E.2
Havinga, R.3
Moshage, H.4
Kuipers, F.5
Jansen, P.L.6
Müller, M.7
-
16
-
-
0031738416
-
Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver
-
Vos, T. A., Hooiveld, G. J., Koning, H., Childs, S., Meijer, D. K., Moshage, H., Jansen, P. L. and Müller, M. (1998) Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver. Hepatology 28, 1637-1644
-
(1998)
Hepatology
, vol.28
, pp. 1637-1644
-
-
Vos, T.A.1
Hooiveld, G.J.2
Koning, H.3
Childs, S.4
Meijer, D.K.5
Moshage, H.6
Jansen, P.L.7
Müller, M.8
-
17
-
-
0034994147
-
Induction of Mdr1b expression by tumor necrosis factor-α in rat liver cells is independent of p53 but requires NF-κB signaling
-
Ros, J. E., Schuetz, J. D., Geuken, M., Streetz, K., Moshage, H., Kuipers, F., Manns, M. P., Jansen, P. L., Trautwein, C. and Müller, M. (2001) Induction of Mdr1b expression by tumor necrosis factor-α in rat liver cells is independent of p53 but requires NF-κB signaling. Hepatology 33, 1425-1431
-
(2001)
Hepatology
, vol.33
, pp. 1425-1431
-
-
Ros, J.E.1
Schuetz, J.D.2
Geuken, M.3
Streetz, K.4
Moshage, H.5
Kuipers, F.6
Manns, M.P.7
Jansen, P.L.8
Trautwein, C.9
Müller, M.10
-
18
-
-
0031018976
-
Regulation of mdr2 P-glycoprotein expression by bile salts
-
Frijters, C. M., Ottenhoff, R., van Wijland, M. J., van Nieuwkerk, C. M., Groen, A. K. and Oude Elferink, R. P. (1997) Regulation of mdr2 P-glycoprotein expression by bile salts. Biochem. J. 321, 389-395
-
(1997)
Biochem. J.
, vol.321
, pp. 389-395
-
-
Frijters, C.M.1
Ottenhoff, R.2
Van Wijland, M.J.3
Van Nieuwkerk, C.M.4
Groen, A.K.5
Oude Elferink, R.P.6
-
19
-
-
0032819120
-
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats
-
Hooiveld, G. J., Vos. T. A., Scheffer, G. L., Van Goor, H., Koning, H., Bloks, V., Loot, A. E., Meijer, D. K., Jansen, P. L., Kuipers, F. and Müller, M. (1999) 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats. Gastroenterology 117, 678-687
-
(1999)
Gastroenterology
, vol.117
, pp. 678-687
-
-
Hooiveld, G.J.1
Vos, T.A.2
Scheffer, G.L.3
Van Goor, H.4
Koning, H.5
Bloks, V.6
Loot, A.E.7
Meijer, D.K.8
Jansen, P.L.9
Kuipers, F.10
Müller, M.11
-
20
-
-
0033061551
-
Enhancement of mdr2 gene transcription mediates the biliary transfer of phosphatidylcholine supplied by an increased biosynthesis in the pravastatin-treated rat
-
Carrella, M., Feldman, D., Cogoi, S., Csillaghy, A. and Weinhold, P. A. (1999) Enhancement of mdr2 gene transcription mediates the biliary transfer of phosphatidylcholine supplied by an increased biosynthesis in the pravastatin-treated rat. Hepatology 29, 1825-1832
-
(1999)
Hepatology
, vol.29
, pp. 1825-1832
-
-
Carrella, M.1
Feldman, D.2
Cogoi, S.3
Csillaghy, A.4
Weinhold, P.A.5
-
21
-
-
0036086885
-
Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats
-
Van Waarde, W. M., Verkade, H. J., Wolters, H., Havinga, R., Baller, J., Bloks, V., Müller, M., Sauer, P. J. and Kuipers, F. (2002) Differential effects of streptozotocin-induced diabetes on expression of hepatic ABC-transporters in rats. Gastroenterology 122, 1842-1852
-
(2002)
Gastroenterology
, vol.122
, pp. 1842-1852
-
-
Van Waarde, W.M.1
Verkade, H.J.2
Wolters, H.3
Havinga, R.4
Baller, J.5
Bloks, V.6
Müller, M.7
Sauer, P.J.8
Kuipers, F.9
-
22
-
-
0029922002
-
Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse
-
Chianale, J., Vollrath, V., Wielandt, A. M., Amigo, L., Rigotti, A., Nervi, F., Gonzalez, S., Andrade, L., Pizarro, M. and Accatino, L. (1996) Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse. Biochem. J. 314, 781-786
-
(1996)
Biochem. J.
, vol.314
, pp. 781-786
-
-
Chianale, J.1
Vollrath, V.2
Wielandt, A.M.3
Amigo, L.4
Rigotti, A.5
Nervi, F.6
Gonzalez, S.7
Andrade, L.8
Pizarro, M.9
Accatino, L.10
-
23
-
-
0032506273
-
Mechanism of action of fibrates on lipid and lipoprotein metabolism
-
Staels, B., Dallongeville, J., Auwerx, J., Schoonjans, K., Leitersdorf, E. and Fruchart, J. C. (1998) Mechanism of action of fibrates on lipid and lipoprotein metabolism. Circulation 98, 2088-2093
-
(1998)
Circulation
, vol.98
, pp. 2088-2093
-
-
Staels, B.1
Dallongeville, J.2
Auwerx, J.3
Schoonjans, K.4
Leitersdorf, E.5
Fruchart, J.C.6
-
24
-
-
0029994543
-
Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
-
Schoonjans, K., Staels, B. and Auwerx, J. (1996) Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression. J. Lipid Res. 37, 907-925
-
(1996)
J. Lipid Res.
, vol.37
, pp. 907-925
-
-
Schoonjans, K.1
Staels, B.2
Auwerx, J.3
-
25
-
-
0028071959
-
The effects of fibrates on lipoprotein and hemostatic coronary risk factors
-
Schonfeld, G. (1994) The effects of fibrates on lipoprotein and hemostatic coronary risk factors. Atherosclerosis 111, 161-174
-
(1994)
Atherosclerosis
, vol.111
, pp. 161-174
-
-
Schonfeld, G.1
-
26
-
-
0033999108
-
Peroxisome proliferator-activated receptor α (PPARα) and agonist inhibit cholesterol 7α-hydroxylase gene (CYP7A1) transcription
-
Marrapodi, M. and Chiang, J. Y. (2000) Peroxisome proliferator-activated receptor α (PPARα) and agonist inhibit cholesterol 7α-hydroxylase gene (CYP7A1) transcription. J. Lipid Res. 41, 514-520
-
(2000)
J. Lipid Res.
, vol.41
, pp. 514-520
-
-
Marrapodi, M.1
Chiang, J.Y.2
-
27
-
-
0034331437
-
The effect of peroxisome-proliferator-activated receptor-α on the activity of the cholesterol 7α-hydroxylase gene
-
Patel, D. D., Knight, B. L., Soutar, A. K., Gibbons, G. F. and Wade, D. P. (2000) The effect of peroxisome-proliferator-activated receptor-α on the activity of the cholesterol 7α-hydroxylase gene. Biochem. J. 351, 747-753
-
(2000)
Biochem. J.
, vol.351
, pp. 747-753
-
-
Patel, D.D.1
Knight, B.L.2
Soutar, A.K.3
Gibbons, G.F.4
Wade, D.P.5
-
28
-
-
0035570381
-
Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-α-mediated downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase expression
-
Post, S. M., Duez, H., Gervois, P. P., Staels, B., Kuipers, F. and Princen, H. M. (2001) Fibrates suppress bile acid synthesis via peroxisome proliferator-activated receptor-α-mediated downregulation of cholesterol 7α-hydroxylase and sterol 27-hydroxylase expression. Arterioscler. Thromb. Vasc. Biol. 21, 1840-1845
-
(2001)
Arterioscler. Thromb. Vasc. Biol.
, vol.21
, pp. 1840-1845
-
-
Post, S.M.1
Duez, H.2
Gervois, P.P.3
Staels, B.4
Kuipers, F.5
Princen, H.M.6
-
29
-
-
0015472014
-
Mechanisms of action of clofibrate on cholesterol metabolism in patients with hyperlipidemia
-
Grundy, S. M., Ahrens, Jr, E. H., Salen, G., Schreibman, P. H. and Nestel, P. J. (1972) Mechanisms of action of clofibrate on cholesterol metabolism in patients with hyperlipidemia. J. Lipid Res. 13, 531-551
-
(1972)
J. Lipid Res.
, vol.13
, pp. 531-551
-
-
Grundy, S.M.1
Ahrens E.H., Jr.2
Salen, G.3
Schreibman, P.H.4
Nestel, P.J.5
-
30
-
-
0021276830
-
Influence of gemfibrozil and clofibrate on metabolism of cholesterol and plasma triglycerides in man
-
Kesaniemi, Y. A. and Grundy, S. M. (1984) Influence of gemfibrozil and clofibrate on metabolism of cholesterol and plasma triglycerides in man. J. Am. Med. Assoc. 251, 2241-2246
-
(1984)
J. Am. Med. Assoc.
, vol.251
, pp. 2241-2246
-
-
Kesaniemi, Y.A.1
Grundy, S.M.2
-
31
-
-
0024509605
-
Biochemical mechanisms of induction of hepatic peroxisome proliferation
-
Lock, E. A., Mitchell, A. M. and Elcombe, C. R. (1989) Biochemical mechanisms of induction of hepatic peroxisome proliferation. Annu. Rev. Pharmacol. Toxicol. 29, 145-163
-
(1989)
Annu. Rev. Pharmacol. Toxicol.
, vol.29
, pp. 145-163
-
-
Lock, E.A.1
Mitchell, A.M.2
Elcombe, C.R.3
-
32
-
-
0030834153
-
Overexpression of mdr2 gene by peroxisome proliferators in the mouse liver
-
Miranda, S., Vollrath, V., Wielandt, A. M., Loyola, G., Bronfman, M. and Chianale, J. (1997) Overexpression of mdr2 gene by peroxisome proliferators in the mouse liver. J. Hepatol. 26, 1331-1339
-
(1997)
J. Hepatol.
, vol.26
, pp. 1331-1339
-
-
Miranda, S.1
Vollrath, V.2
Wielandt, A.M.3
Loyola, G.4
Bronfman, M.5
Chianale, J.6
-
33
-
-
0028997684
-
Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
-
Lee, S. S., Pineau, T., Drago, J., Lee, E. J., Owens, J. W., Kroetz, D. L., Fernandez-Salguero, P. M., Westphal, H. and Gonzalez, F. J. (1995) Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell Biol. 15, 3012-3022
-
(1995)
Mol. Cell Biol.
, vol.15
, pp. 3012-3022
-
-
Lee, S.S.1
Pineau, T.2
Drago, J.3
Lee, E.J.4
Owens, J.W.5
Kroetz, D.L.6
Fernandez-Salguero, P.M.7
Westphal, H.8
Gonzalez, F.J.9
-
34
-
-
0029893226
-
Altered lipid metabolism in apolipoprotein E-deficient mice does not affect cholesterol balance across the liver
-
Kuipers, F., van Ree, J. M., Hofker, M. H. Wolters, H., In't, V. G., Havinga, R., Vonk, R. J., Princen, H. M. and Havekes, L. M. (1996) Altered lipid metabolism in apolipoprotein E-deficient mice does not affect cholesterol balance across the liver. Hepatology 24, 241-247
-
(1996)
Hepatology
, vol.24
, pp. 241-247
-
-
Kuipers, F.1
Van Ree, J.M.2
Hofker, M.H.3
Wolters, H.4
In't, V.G.5
Havinga, R.6
Vonk, R.J.7
Princen, H.M.8
Havekes, L.M.9
-
35
-
-
0031467633
-
Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E-deficient mouse hepatocytes
-
Kuipers, F., Jong, M. C., Lin, Y., Eck, M, Havinga, R., Bloks, V., Verkade, H. J., Hofker, M. H., Moshage, H., Berkel, T. J. et al. (1997) Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E-deficient mouse hepatocytes. J. Clin. Invest. 100, 2915-2922
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2915-2922
-
-
Kuipers, F.1
Jong, M.C.2
Lin, Y.3
Eck, M.4
Havinga, R.5
Bloks, V.6
Verkade, H.J.7
Hofker, M.H.8
Moshage, H.9
Berkel, T.J.10
-
36
-
-
0029957181
-
Real time quantitative PCR
-
Heid, C. A., Stevens, J., Livak, K. J. and Williams, P. M. (1996) Real time quantitative PCR. Genome Res. 6, 986-994
-
(1996)
Genome Res.
, vol.6
, pp. 986-994
-
-
Heid, C.A.1
Stevens, J.2
Livak, K.J.3
Williams, P.M.4
-
37
-
-
0037072809
-
Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1
-
Plösch, T., Kok, T., Bloks, V. W., Smit, M. J., Havinga, R., Chimini, G., Groen, A. K. and Kuipers, F. (2002) Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1. J. Biol. Chem. 277, 33870-33877
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 33870-33877
-
-
Plösch, T.1
Kok, T.2
Bloks, V.W.3
Smit, M.J.4
Havinga, R.5
Chimini, G.6
Groen, A.K.7
Kuipers, F.8
-
38
-
-
0037219280
-
Induction of hepatic ABC transporter expression is part of the PPARα-mediated fasting response in the mouse
-
in the press
-
Kok, T., Wolters, H., Bloks, V. W., Havinga, R., Jansen, P. L. M., Staels, B. and Kuipers, F. (2003) Induction of hepatic ABC transporter expression is part of the PPARα-mediated fasting response in the mouse. Gastroenterology, in the press
-
(2003)
Gastroenterology
-
-
Kok, T.1
Wolters, H.2
Bloks, V.W.3
Havinga, R.4
Jansen, P.L.M.5
Staels, B.6
Kuipers, F.7
-
39
-
-
0032897183
-
+-taurocholate cotransporting protein (Ntcp) in livers of mdr2 P-glycoprotein-deficient mice
-
+-taurocholate cotransporting protein (Ntcp) in livers of mdr2 P-glycoprotein-deficient mice. J. Hepatol. 30, 14-21
-
(1999)
J. Hepatol.
, vol.30
, pp. 14-21
-
-
Koopen, N.R.1
Wolters, H.2
Voshol, P.3
Stieger, B.4
Vonk, R.J.5
Meier, P.J.6
Kuipers, F.7
Hagenbuch, B.8
-
40
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, D. H., Rosebrough, A. L., Farr, A. L. and Randal, R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, D.H.1
Rosebrough, A.L.2
Farr, A.L.3
Randal, R.J.4
-
41
-
-
0018568509
-
Validation of a recording spectrophotometric method for measurement of membrane-associated Mg- and NaK-ATPase activity
-
Scharschmidt, B. F., Keefee, E. B., Blankenship, N. M. and Ockner, R. K. (1979) Validation of a recording spectrophotometric method for measurement of membrane-associated Mg- and NaK-ATPase activity. J. Lab. Clin. Med. 93, 790-799
-
(1979)
J. Lab. Clin. Med.
, vol.93
, pp. 790-799
-
-
Scharschmidt, B.F.1
Keefee, E.B.2
Blankenship, N.M.3
Ockner, R.K.4
-
42
-
-
0018654116
-
Studies of relationship among bile flow, liver plasma membrane NaK-ATPase, and membrane microviscosity in the rat
-
Keefee, E. B., Scharschmidt, B. F., Blankenship, N. M. and Ockner, R. K. (1979) Studies of relationship among bile flow, liver plasma membrane NaK-ATPase, and membrane microviscosity in the rat. J. Clin. Invest. 64, 1590-1598
-
(1979)
J. Clin. Invest.
, vol.64
, pp. 1590-1598
-
-
Keefee, E.B.1
Scharschmidt, B.F.2
Blankenship, N.M.3
Ockner, R.K.4
-
43
-
-
0017196437
-
A simple and sensitive assay of total serum bile acids
-
Mashige, F., Imai, K. and Osuga, T. (1976) A simple and sensitive assay of total serum bile acids. Clin. Chim. Acta 70, 79-86
-
(1976)
Clin. Chim. Acta
, vol.70
, pp. 79-86
-
-
Mashige, F.1
Imai, K.2
Osuga, T.3
-
44
-
-
0021934109
-
Enterohepatic circulation in the rat
-
Kuipers, F., Havinga, R., Bosschieter, H., Toorop, G. P., Hindriks, F. R. and Vonk, R. J. (1985) Enterohepatic circulation in the rat. Gastroenterology 88, 403-411
-
(1985)
Gastroenterology
, vol.88
, pp. 403-411
-
-
Kuipers, F.1
Havinga, R.2
Bosschieter, H.3
Toorop, G.P.4
Hindriks, F.R.5
Vonk, R.J.6
-
45
-
-
0028276397
-
Peroxisome proliferator-activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids
-
Rodriguez, J. C., Gil-Gomez, G., Hegardt, F. G. and Haro, D. (1994) Peroxisome proliferator-activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids. J. Biol. Chem. 269, 18767-18772
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18767-18772
-
-
Rodriguez, J.C.1
Gil-Gomez, G.2
Hegardt, F.G.3
Haro, D.4
-
46
-
-
0032179725
-
Transcriptional regulation of mitochondrial HMG-CoA synthase in the control of ketogenesis
-
Hegardt, F. G. (1998) Transcriptional regulation of mitochondrial HMG-CoA synthase in the control of ketogenesis. Biochimie 80, 803-806
-
(1998)
Biochimie
, vol.80
, pp. 803-806
-
-
Hegardt, F.G.1
-
47
-
-
0030766476
-
Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice
-
Peters, J. M., Hennuyer, N., Staels, B., Fruchart, J. C., Fievet, C., Gonzalez, F. J. and Auwerx, J. (1997) Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice. J. Biol. Chem. 272, 27307-27312
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27307-27312
-
-
Peters, J.M.1
Hennuyer, N.2
Staels, B.3
Fruchart, J.C.4
Fievet, C.5
Gonzalez, F.J.6
Auwerx, J.7
-
48
-
-
0032169919
-
Fenofibrate modifies transaminase gene expression via a peroxisome proliferator activated receptor α-dependent pathway
-
Edgar, A. D., Tomkiewicz, C., Costet, P., Legendre, C., Aggerbeck, M., Bouguet, J., Staels, B., Guyomard, C., Pineau, T. and Barouki, R. (1998) Fenofibrate modifies transaminase gene expression via a peroxisome proliferator activated receptor α-dependent pathway. Toxicol. Lett. 98, 13-23
-
(1998)
Toxicol. Lett.
, vol.98
, pp. 13-23
-
-
Edgar, A.D.1
Tomkiewicz, C.2
Costet, P.3
Legendre, C.4
Aggerbeck, M.5
Bouguet, J.6
Staels, B.7
Guyomard, C.8
Pineau, T.9
Barouki, R.10
-
49
-
-
0035987894
-
Tissue distribution and chemical induction of multiple drug resistance genes in rats
-
Brady, J. M., Cherrington, N. J., Hartley, D. P., Buist, S. C., Li, N. and Klaassen, C. D. (2002) Tissue distribution and chemical induction of multiple drug resistance genes in rats. Drug Metab. Dispos. 30, 838-844
-
(2002)
Drug Metab. Dispos.
, vol.30
, pp. 838-844
-
-
Brady, J.M.1
Cherrington, N.J.2
Hartley, D.P.3
Buist, S.C.4
Li, N.5
Klaassen, C.D.6
-
50
-
-
0032874718
-
Biliary fibrosis associated with altered bile composition in a mouse model of erythropoietic protoporphyria
-
Meerman, L., Koopen, N. R., Bloks, V., Van Goor, H., Havinga, R., Wolthers, B. G., Kramer, W., Stengelin, S., Muller, M., Kuipers, F. and Jansen, P. L. M. (1999) Biliary fibrosis associated with altered bile composition in a mouse model of erythropoietic protoporphyria. Gastroenterology 117, 696-705
-
(1999)
Gastroenterology
, vol.117
, pp. 696-705
-
-
Meerman, L.1
Koopen, N.R.2
Bloks, V.3
Van Goor, H.4
Havinga, R.5
Wolthers, B.G.6
Kramer, W.7
Stengelin, S.8
Muller, M.9
Kuipers, F.10
Jansen, P.L.M.11
-
51
-
-
0035852720
-
Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis
-
Wang, R., Salem, M., Yousef, I. M., Tuchweber, B., Lam, P., Childs, S. J., Helgason, C. D., Ackerley, C., Phillips, M. J. and Ling, V. (2001) Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis. Proc. Natl. Acad. Sci. U.S.A. 98, 2011-2016
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 2011-2016
-
-
Wang, R.1
Salem, M.2
Yousef, I.M.3
Tuchweber, B.4
Lam, P.5
Childs, S.J.6
Helgason, C.D.7
Ackerley, C.8
Phillips, M.J.9
Ling, V.10
-
52
-
-
0027263324
-
Mechanism of biliary lipid secretion in the rat: A role for bile acid-independent bile flow?
-
Verkade, H. J., Wolters, H., Gerding, A., Havinga, R., Fidler, V., Vonk, R. J. and Kuipers, F. (1993) Mechanism of biliary lipid secretion in the rat: a role for bile acid-independent bile flow? Hepatology 17, 1074-1080
-
(1993)
Hepatology
, vol.17
, pp. 1074-1080
-
-
Verkade, H.J.1
Wolters, H.2
Gerding, A.3
Havinga, R.4
Fidler, V.5
Vonk, R.J.6
Kuipers, F.7
-
53
-
-
0025147358
-
The uncoupling of biliary lipid from bile acid secretion by organic anions in the rat
-
Verkade, H. J., Wolbers, M. J., Havinga, R., Uges, D. R., Vonk, R. J. and Kuipers, F. (1990) The uncoupling of biliary lipid from bile acid secretion by organic anions in the rat. Gastroenterology 99, 1485-1492
-
(1990)
Gastroenterology
, vol.99
, pp. 1485-1492
-
-
Verkade, H.J.1
Wolbers, M.J.2
Havinga, R.3
Uges, D.R.4
Vonk, R.J.5
Kuipers, F.6
-
54
-
-
4243676514
-
Induction of hepatic Mdr2 expression by cholesterol synthesis inhibitors (statins) is mediated via SREBPs
-
Hooiveld, G. J., Heegsma, J. H., Silverman, J. A., Groothuis, G. M., Jansen, P. L. M., Meijer, D. K., Kuipers, F. and Müller, M. (1999) Induction of hepatic Mdr2 expression by cholesterol synthesis inhibitors (statins) is mediated via SREBPs. Hepatology 30(4), 428A
-
(1999)
Hepatology
, vol.30
, Issue.4
-
-
Hooiveld, G.J.1
Heegsma, J.H.2
Silverman, J.A.3
Groothuis, G.M.4
Jansen, P.L.M.5
Meijer, D.K.6
Kuipers, F.7
Müller, M.8
-
55
-
-
0033868565
-
Regulation of multidrug resistance 2 P-glycoprotein expression by bile salts in rats and in primary cultures of rat hepatocytes
-
Gupta, S., Todd, S. R., Pandak, W. M., Müller, M., Reno, V. Z. and Hylemon, P. B. (2000) Regulation of multidrug resistance 2 P-glycoprotein expression by bile salts in rats and in primary cultures of rat hepatocytes. Hepatology 32, 341-347
-
(2000)
Hepatology
, vol.32
, pp. 341-347
-
-
Gupta, S.1
Todd, S.R.2
Pandak, W.M.3
Müller, M.4
Reno, V.Z.5
Hylemon, P.B.6
-
56
-
-
0001168852
-
Induction of Mdr2 P-glycoprotein (Pgp) by fibrates is mediated by peroxisome proliferator-activated receptor alpha (PPARα) in the mouse
-
Kok, T., Bloks, V., Wolters, H., Jansen, P. L. M., Staels, B. and Kuipers, F. (2001) Induction of Mdr2 P-glycoprotein (Pgp) by fibrates is mediated by peroxisome proliferator-activated receptor alpha (PPARα) in the mouse. Hepatology 34(4), 374A
-
(2001)
Hepatology
, vol.34
, Issue.4
-
-
Kok, T.1
Bloks, V.2
Wolters, H.3
Jansen, P.L.M.4
Staels, B.5
Kuipers, F.6
|