Molecular mechanisms underlying membrane-potential-mediated regulation of neuronal K2P2.1 channels

Molecular and Cellular Neuroscience

Volumn 43, Issue 1, 2010, Pages 117-126

  Segal Hayoun, Yifat ^a   Cohen, Asi ^a   Zilberberg, Noam ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C; POTASSIUM CHANNEL KCNK2; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ARTICLE; CONTROLLED STUDY; ELECTRIC FIELD; HETEROLOGOUS EXPRESSION; HYPERPOLARIZATION; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CURRENT; PRIORITY JOURNAL; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; ENZYME INHIBITORS; GENE SILENCING; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; MOLECULAR SEQUENCE DATA; NEURONS; OOCYTES; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; RECEPTORS, G-PROTEIN-COUPLED; SEQUENCE ALIGNMENT; TYPE C PHOSPHOLIPASES; XENOPUS LAEVIS;

EID: 72149108702     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2009.10.002     Document Type: Article

References (61)

1. + current ITREK in cardiomyocytes. J. Biol. Chem. 275 (2000) 39110-39116
2. + channel involved in polymodal pain perception. EMBO J. 25 (2006) 2368-2376
3. Backx P.H., and Marban E. Background potassium current active during the plateau of the action potential in guinea pig ventricular myocytes. Circ. Res. 72 (1993) 890-900
4. Barel O., Shalev S.A., Ofir R., Cohen A., Zlotogora J., Shorer Z., Mazor G., Finer G., Khateeb S., Zilberberg N., and Birk O.S. Maternally inherited Birk Barel mental retardation dysmorphism syndrome caused by a mutation in the genomically imprinted potassium channel KCNK9. Am. J. Hum. Genet. 83 (2008) 193-199
5. Ben-Chaim Y., Chanda B., Dascal N., Bezanilla F., Parnas I., and Parnas H. Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor. Nature 444 (2006) 106-109
6. Bockenhauer D., Zilberberg N., and Goldstein S.A. KCNK2: reversible conversion of a hippocampal potassium leak into a voltage-dependent channel. Nat. Neurosci. 4 (2001) 486-491
7. Bolton S., Greenwood K., Hamilton N., and Butt A.M. Regulation of the astrocyte resting membrane potential by cyclic AMP and protein kinase A. Glia 54 (2006) 316-328
8. Brenner T., and O'Shaughnessy K.M. Both TASK-3 and TREK-1 two-pore loop K channels are expressed in H295R cells and modulate their membrane potential and aldosterone secretion. Am. J. Physiol. Endocrinol. Metab. 295 (2008) E1480-1486
9. Brickley S.G., Aller M.I., Sandu C., Veale E.L., Alder F.G., Sambi H., Mathie A., and Wisden W. TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons. J. Neurosci. 27 (2007) 9329-9340
10. + channels. EMBO J. 22 (2003) 5403-5411
11. + channel TREK-1. EMBO J. 24 (2005) 44-53
12. Chen X., Talley E.M., Patel N., Gomis A., McIntire W.E., Dong B., Viana F., Garrison J.C., and Bayliss D.A. Inhibition of a background potassium channel by Gq protein alpha-subunits. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 3422-3427
13. Choe S. Potassium channel structures. Nat. Rev. Neurosci. 3 (2002) 115-121
14. Cohen A., and Zilberberg N. Fluctuations in Xenopus oocytes protein phosphorylation levels during two-electrode voltage clamp measurements. J. Neurosci. Methods 153 (2006) 62-70
15. 2P2.1 channel gating. Facilitation of C-type gating by protonation of extracellular histidine residues. J. Biol. Chem. 283 (2008) 19448-19455
16. Cohen A., Ben-Abu Y., and Zilberberg N. Gating the pore of potassium leak channels. Eur. Biophys. J. (2009) DOI 10.1007/s00249-009-0457-6
17. 2P2.1 channel. Mol. Cell. Neurosci. 40 (2009) 382-389
18. + channel. EMBO J. 15 (1996) 6854-6862
19. 2+ transients in guinea-pig coronary myocytes. J. Physiol. 470 (1993) 35-44
20. Goldstein S.A., Bockenhauer D., O'Kelly I., and Zilberberg N. Potassium leak channels and the KCNK family of two-P-domain subunits. Nat. Rev. Neurosci. 2 (2001) 175-184
21. Halaszovich C.R., Schreiber D.N., and Oliver D. Ci-VSP is a depolarization-activated phosphatidylinositol-4,5-bisphosphate and phosphatidylinositol-3,4,5-trisphosphate 5′-phosphatase. J. Biol. Chem. 284 (2009) 2106-2113
22. + channel involved in neuroprotection and general anesthesia. EMBO J. 23 (2004) 2684-2695
23. Heurteaux C., Lucas G., Guy N., El Yacoubi M., Thummler S., Peng X.D., Noble F., Blondeau N., Widmann C., Borsotto M., Gobbi G., Vaugeois J.M., Debonnel G., and Lazdunski M. Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype. Nat. Neurosci. 9 (2006) 1134-1141
24. Hille B. Ion Channels of Excitable Membranes. 3rd ed (2001), Sinauer Associates Press, Sanderland, MA, USA
25. 2P channels: focus on TREK1. Nat. Rev. Neurosci. 8 (2007) 251-261
26. Hossain M.I., Iwasaki H., Okochi Y., Chahine M., Higashijima S., Nagayama K., and Okamura Y. Enzyme domain affects the movement of the voltage sensor in ascidian and zebrafish voltage-sensing phosphatases. J. Biol. Chem. 283 (2008) 18248-18259
27. Itoh T., Seki N., Suzuki S., Ito S., Kajikuri J., and Kuriyama H. Membrane hyperpolarization inhibits agonist-induced synthesis of inositol 1,4,5-trisphosphate in rabbit mesenteric artery. J. Physiol. 451 (1992) 307-328
28. Iwasaki H., Murata Y., Kim Y., Hossain M.I., Worby C.A., Dixon J.E., McCormack T., Sasaki T., and Okamura Y. A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate. Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 7970-7975
29. Jan L.Y., and Jan Y.N. Potassium channels and their evolving gates. Nature 371 (1994) 119-122
30. Koh S.D., Monaghan K., Sergeant G.P., Ro S., Walker R.L., Sanders K.M., and Horowitz B. TREK-1 regulation by nitric oxide and cGMP-dependent protein kinase. An essential role in smooth muscle inhibitory neurotransmission. J. Biol. Chem. 276 (2001) 44338-44346
31. Lalevee N., Monier B., Senatore S., Perrin L., and Semeriva M. Control of cardiac rhythm by ORK1, a Drosophila two-pore domain potassium channel. Curr. Biol. 16 (2006) 1502-1508
32. Lopatin A.N., Makhina E.N., and Nichols C.G. Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification. Nature 372 (1994) 366-369
33. + channels. J. Physiol. 564 (2005) 117-129
34. + channels. Channels (Austin) 1 (2007) 124-134
35. MacKinnon R. Potassium channels. FEBS Lett. 555 (2003) 62-65
36. Mahaut-Smith M.P., Martinez-Pinna J., and Gurung I.S. A role for membrane potential in regulating GPCRs?. Trends Pharmacol. Sci. 29 (2008) 421-429
37. Maingret F., Patel A.J., Lesage F., Lazdunski M., and Honore E. Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel. J. Biol. Chem. 274 (1999) 26691-26696
38. + channel. Biochem. Biophys. Res. Commun. 292 (2002) 339-346
39. Mathie A. Neuronal two-pore-domain potassium channels and their regulation by G protein-coupled receptors. J. Physiol. 578 (2007) 377-385
40. Matsuyama H., Nguyen T.V., Hunne B., Thacker M., Needham K., McHugh D., and Furness J.B. Evidence that TASK1 channels contribute to the background current in AH/type II neurons of the guinea-pig intestine. Neuroscience 155 (2008) 738-750
41. McBride T. Increased depolarization, prolonged recovery and reduced adaptation of the resting membrane potential in aged rat skeletal muscles following eccentric contractions. Mech. Ageing. Dev. 115 (2000) 127-138
42. Mu D., Chen L., Zhang X., See L.H., Koch C.M., Yen C., Tong J.J., Spiegel L., Nguyen K.C., Servoss A., Peng Y., Pei L., Marks J.R., Lowe S., Hoey T., Jan L.Y., McCombie W.R., Wigler M.H., and Powers S. Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell 3 (2003) 297-302
43. 2. J. Physiol. 583 (2007) 875-889
44. Murata Y., Iwasaki H., Sasaki M., Inaba K., and Okamura Y. Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor. Nature 435 (2005) 1239-1243
45. Murbartian J., Lei Q., Sando J.J., and Bayliss D.A. Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels. J. Biol. Chem. 280 (2005) 30175-30184
46. 2+ signalling in development and maturation of mammalian cerebellar granule cells. J. Physiol. 575 (2006) 389-395
47. Nakanishi S., Catt K.J., and Balla T. A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 5317-5321
48. + channels TRAAK and TREK-1 control both warm and cold perception. EMBO J. 28 (2009) 1308-1318
49. + channel function. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 7803-7807
50. Poulet J.F., and Petersen C.C. Internal brain state regulates membrane potential synchrony in barrel cortex of behaving mice. Nature 454 (2008) 881-885
51. Ramsey I.S., Moran M.M., Chong J.A., and Clapham D.E. A voltage-gated proton-selective channel lacking the pore domain. Nature 440 (2006) 1213-1216
52. Sheeba V., Gu H., Sharma V.K., O'Dowd D.K., and Holmes T.C. Circadian- and light-dependent regulation of resting membrane potential and spontaneous action potential firing of Drosophila circadian pacemaker neurons. J. Neurophysiol. 99 (2008) 976-988
53. Suh B.C., and Hille B. Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis. Neuron 35 (2002) 507-520
54. 2P2.1 potassium channels permeable to sodium. Neuron 58 (2008) 859-870
55. Vandenberg C.A. Inward rectification of a potassium channel in cardiac ventricular cells depends on internal magnesium ions. Proc. Natl. Acad. Sci. U. S. A. 84 (1987) 2560-2564
56. Voloshyna I., Besana A., Castillo M., Matos T., Weinstein I.B., Mansukhani M., Robinson R.B., Cordon-Cardo C., and Feinmark S.J. TREK-1 is a novel molecular target in prostate cancer. Cancer Res. 68 (2008) 1197-1203
57. + channel TASK-3 coupled to 5-HT2C receptors. Eur. J. Neurosci. 28 (2008) 931-940
58. Yellen G. The voltage-gated potassium channels and their relatives. Nature 419 (2002) 35-42
59. 2 activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents. Neuron 37 (2003) 963-975
60. Zhang H., Shepherd N., and Creazzo T.L. Temperature-sensitive TREK currents contribute to setting the resting membrane potential in embryonic atrial myocytes. J. Physiol. 586 (2008) 3645-3656
61. Zilberberg N., Ilan N., Gonzalez-Colaso R., and Goldstein S.A. Opening and closing of KCNKO potassium leak channels is tightly regulated. J. Gen. Physiol. 116 (2000) 721-734