Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis

Neuron

Volumn 35, Issue 3, 2002, Pages 507-520

  Suh, Byung Chang ^a   Hille, Bertil ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; GUANINE NUCLEOTIDE BINDING PROTEIN; LINOPIRDINE; LIPID; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOTRANSFERASE INHIBITOR;

ARTICLE; DIFFUSION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; NERVE CELL EXCITABILITY; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 0036683972     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(02)00790-0     Document Type: Article

References (57)

1. Myosin light chain kinase occurs in bullfrog sympathetic neurons and may modulate voltage-dependent potassium currents
2. Evidence for myosin light chain kinase mediating noradrenaline-evoked cation current in rabbit portal vein myocytes
3. Phosphatidylinositol 4-kinases
4. 2+ current and M current in rat sympathetic neurons
5. Protein kinase C is not necessary for peptide-induced suppression of M current or for desensitization of the peptide receptors
6. + current in a vertebrate neuron
7. o in rat sympathetic neurones
8. M-currents in frog sympathetic ganglion cells: Manipulation of membrane phosphorylation
9. 2+ channels involves multiple receptor subtypes in cortical neurons
10. 2+ stores in rat sympathetic neurons
11. 3 pathways in neurons
12. 2+ mobilisation in rat sympathetic neurones, but this signalling pathway does not mediate M-current inhibition
13. PI 3-kinase: Structural and functional analysis of intersubunit interactions
14. Synthesis and properties of diastereoisomers of adenosine 5′-(O-1-thiotriphosphate) and adenosine 5′-(O-2-thiotriphosphate)
15. Anionic phospholipids activate ATP-sensitive potassium channels
16. q contributes to muscarinic inhibition of the M-type potassium current in sympathetic neurons
17. Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-β4
18. 2 with ion channels and transporters
19. Modulation of ion-channel function by G-protein-coupled receptors
20. 2 and its stabilization by Gβγ
21. Disruption by lithium of phosphatidylinositol-4,5-bisphosphate supply and inositol-1,4,5-trisphosphate generation in Chinese hamster ovary cells expressing human recombinant M1 muscarinic receptors
22. q/11
23. M) and some other voltage- and ligand-gated membrane currents in rat sympathetic neurons
24. Attenuation of focal adhesion kinase signaling following depletion of agonist-sensitive pools of phosphatidylinositol 4,5-bisphosphate
25. Selective reduction of one mode of M-channel gating by muscarine in sympathetic neurons
26. Control of M current
27. Cloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinase
28. K-252a, a novel microbial product, inhibits smooth muscle myosin light chain kinase
29. Wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids
30. Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase
31. 2+ transients, but these events do not explain M-current suppression
32. Regulation of myosin phosphorylation in smooth muscle
33. SRF-dependent gene expression is required for mitogen-induced proliferation through a PI3 kinase signal transduction cascade
34. Inhibitory effect of phosphorylated myosin light chain kinase on the ATP-dependent actin-myosin interaction
35. Effects of arsenicals on the secretory process in chromaffin cells
36. Closure of potassium M-channels by muscarinic acetylcholine-receptor stimulants requires a diffusible messenger
37. Angiotensin II inhibits calcium and M current channels in rat sympathetic neurons via G-proteins
38. 2+ channels by PTX-sensitive G-proteins is blocked by N-ethylmaleimide in rat sympathetic neurons
39. + channels that underlie the neuronal M current
40. Membrane phospholipid control of nucleotide sensitivity of KATP channels
41. Regulation of M-type potassium current by intracellular nucleotide phosphates
42. Desensitization of the inhibition of the M current in sympathetic neurons: Effects of ATP analogues, polyanions, and multiple agonist applications
43. Regulation of the responses to gonadotropin-releasing hormone, muscarine and substance P in sympathetic neurons by changes in cellular constituents and intracellular application of peptide fragments of the substance P receptor
44. A role for a wortmannin-sensitive phosphatidylinositol-4-kinase in the endocytosis of muscarinic cholinergic receptors
45. 2+ elevation by muscarinic stimulation without attenuation of inositol 1,4,5-trisphosphate production in human neuroblastoma SK-N-BE(2)C cells
46. + ions depends on the presence of phosphatidylinositol phosphates
47. ATP regulates muscarine-sensitive potassium current in dissociated bull-frog primary afferent neurons
48. Inhibition by wortmannin of M-current in bullfrog sympathetic neurones
49. 3H]inositol-labeled phosphoinositide pools
50. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
51. Potassium currents in rat prevertebral and paravertebral sympathetic neurones: Control of firing properties
52. 2+ influx in endothelial cells
53. Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion
54. Differential regulation of muscarinic acetylcholine receptor-sensitive polyphosphoinositide pools and consequences for signaling in human neuroblastoma cells
55. Phospholipase C-linked receptors regulate the ATP-sensitive potassium channel by means of phosphatidylinositol 4,5-bisphosphate metabolism
56. Endogenous voltage-gated potassium channels in human embryonic kidney (HEK293) cells
57. Inhibition of phosphatidylinositol 4-kinase results in a significant reduced respiratory burst in formyl-methionyl-leucyl-phenylalanine-stimulated human neutrophils