PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels

Journal of Physiology

Volumn 564, Issue 1, 2005, Pages 117-129

  Lopes, Coeli M B ^a   Rohács, Tibor ^a   Czirják, Gábor ^b   Balla, Tamás ^c   Enyedi, Péter ^b,c   Logothetis, Diomedes E ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b SEMMELWEIS UNIVERSITY   (Hungary)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALPHOSTIN C; DIACYLGLYCEROL; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POLYLYSINE; POTASSIUM CHANNEL KCNQ1; PROTEIN KINASE C; TANDEM PORE DOMAIN POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL; WORTMANNIN; ANDROSTANE DERIVATIVE; G PROTEIN COUPLED RECEPTOR; INWARDLY RECTIFYING POTASSIUM CHANNEL; POTASSIUM CHANNEL; POTASSIUM CHANNEL TASK1; POTASSIUM CHANNEL TASK3; POTASSIUM CHANNEL TRAAK; POTASSIUM CHANNEL TREK1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME INHIBITION; FEMALE; HORMONE RELEASE; HUMAN; HYDROLYSIS; KINETICS; MEMBRANE ELECTROPHYSIOLOGY; MEMBRANE STEADY POTENTIAL; NONHUMAN; PRIORITY JOURNAL; XENOPUS; ANIMAL; CHANNEL GATING; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; RAT; ACTION POTENTIAL DURATION; ENZYME ACTIVATION; MECHANICAL STIMULATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN PROTEIN INTERACTION; RECURRENT INHIBITION;

ANDROSTADIENES; ANIMALS; FEMALE; HUMANS; HYDROLYSIS; ION CHANNEL GATING; MICE; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POLYLYSINE; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN STRUCTURE, TERTIARY; RATS; XENOPUS;

EID: 17444412716     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2004.081935     Document Type: Article

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