Ion channel structure: Potassium channel structures

Nature Reviews Neuroscience

Volumn 3, Issue 2, 2002, Pages 115-121

  Choe, Senyon ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; HUMAN; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

ANIMALS; CELL MEMBRANE; HUMANS; MEMBRANE POTENTIALS; POTASSIUM; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

EID: 0036482015     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn727     Document Type: Article

References (40)

1. Hodgkin, A. L. & Huxley, A. F. A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. (Lond.) 117, 500-544 (1952).
2. Hille, B. Ionic Channels of Excitable Membranes 3rd edn (Sinauer Associates, Sunderland, Massachusetts, 2001).
3. + conduction and selectivity. Science 280, 69-77 (1998).
4. Armstrong, C. M. & Hille, B. Voltage-gated ion channels and electrical excitability. Neuron 20, 371-380 (1998).
5. Lu, Z., Klem, A. M. & Ramu, Y Ion conduction pore is conserved among potassium channels. Nature 413, 809-813 (2001).
6. Biggin, P C., Roosild, T. & Choe, S. Potassium channel structure: domain by domain. Curr. Opin. Struct. Biol. 10, 456-461 (2000).
7. + channel and demonstration of its presence in the human BK channel. Neuron 29, 593-601 (2001).
8. Bezanilla, F. & Armstrong, C. M. Negative conductance caused by entry of sodium and cesium ions into the potassium channels of squid axons. J. Gen. Physiol. 60, 588-608 (1972).
9. + channel-Fab complex at 2.0 Å resolution. Nature 414, 43-48 (2001).
10. Morais-Cabral, J. H., Zhou, Y & MacKinnon, R. Energetic optimization of ion conduction rate by the K+ selectivity filter. Nature 414, 37-42 (2001).
11. + channel. Nature 414, 73-77 (2001).
12. +-channel activation gating. Science 285, 73-78 (1999).
13. Cha, A., Snyder, G. E., Selvin, P R. & Bezanilla, F. Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy. Nature 402, 809-813 (1999).
14. Glauner, K. S., Mannuzzu, L. M., Gandhi, C. S. & Isacoff, E. Y. Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel. Nature 402, 813-817 (1999).
15. + channels and the prokaryotic KcsA channel. J. Biol. Chem. 276, 21070-21076 (2001).
16. Choe, S., Kreusch, A. & Pfaffinger, P. J. Towards the three- dimensional structure of voltage-gated potassium channels. Trends Biochem. Sci. 24, 345-349 (1999).
17. + channel. Nature 353, 86-90 (1991).
18. + channel. Neuron 19, 175-184 (1997).
19. Gulbis, J. M., Mann, S. & MacKinnon, R. Structure of a voltage-dependent K+ channel p subunit. Cell 97, 943-952 (1999).
20. Li, M., Jan, Y N. & Jan, L. Y Specification of subunit assembly by the hydrophilic amino-terminal domain of the Shaker potassium channel. Science 257, 1225-1230
21. Shen, N. V, Chen, X., Boyer, M. M. & Pfaffinger, P J. Deletion analysis of K+ channel assembly. Neuron 11, 67-76. (1993).
22. Zerangue, N., Jan, Y N. & Jan, L. Y An artificial tetramerization domain restores efficient assembly of functional Shaker channels lacking T1. Proc. Natl Acad. Sci. USA 97, 3591-3595 (2000).
23. Kreusch, A., Pfaffinger, P., Stevens, C. F. & Choe, S. Crystal structure of the tetramerization domain of the Shaker potassium channel. Nature 392, 945-948 (1998).
24. 2+-mediated and molecular determinants of tetramerization in voltage-gated K+ channels. Nature Struct. Biol. 6, 38-43 (1999).
25. Cushman, S. J. et al. Voltage-dependent activation of potassium channels is coupled to T1 domain structure. Nature Struct. Biol. 7, 403-407 (2000).
26. Minor, D. L. et al. The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell 102, 657-670 (2000).
27. Zhou, M., Morais-Cabral, J., Mann, S. & MacKinnon, R. Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors. Nature 411, 657-661 (2001).
28. Roeper, J. et al. NIP domain prevents N-type inactivation in voltage-gated potassium channels. Nature 391, 390-393 (1998).
29. Kubo, Y, Reuveny, E., Slesinger, P. A., Jan, Y N. & Jan, L. Y Primary structure and functional expression of a rat G- protein-coupled muscarinic potassium channel. Nature 364, 802-806 (1993).
30. Holmes, T. C., Fadool, D. A., Ren, R. & Levitan, I. B. Association of Src tyrosine kinase with a human potassium channel mediated by SH3 domain. Science 274, 2089-2091 (1996).
31. Adams, J. P et al. The A-type potassium channel Kv4.2 is a substrate for the mitogen-activated protein kinase ERK. J. Neurochem. 75, 2277-2287 (2000).
32. Impey, S., Obrietan, K. & Storm, D. R. Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity. Neuron 23, 11-14 (1999).
33. An, W. F. et al. Modulation of A-type potassium channels by a family of calcium sensors. Nature 403, 553-556 (2000).
34. 2+/calmodulin. Nature 410, 1120-1124 (2001).
35. Flynn, G. E., Johnson, J. P. Jr & Zagotta, W. N. Cyclic nucleotide-gated channels: shedding light on the opening of a channel pore. Nature Rev. Neurosci. 2, 643-651 (2001).
36. Bateman, A. et al. The Pfam protein families database. Nucleic Acids Res. 28, 263-266 (2000).
37. Buxbaum, J. D. et al. Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment. Nature Med. 4, 1177-1181 (1998).
38. 2+-regulated transcriptional repressor. Nature 398, 80-84 (1999).
39. Goldstein, S. A., Bockenhauer, D., O'Kelly, I. & Zilberberg, N. Potassium leak channels and the KCNK family of two-P- domain subunits. Nature Re. Neurosci. 2, 175-184 (2001).
40. Antz, C. et al. NMR structure of inactivation gates from mammalian voltage-dependent potassium channels. Nature 385, 272-274 (1997).