Synthesis and evaluation of a thio analogue of duocarmycin SA

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 24, 2009, Pages 6962-6965

  MacMillan, Karen S ^a   Lajiness, James P ^a   Cara, Carlota Lopez ^b   Romagnoli, Romeo ^b   Robertson, William M ^a   Hwang, Inkyu ^a   Baraldi, Pier Giovanni ^b   Boger, Dale L ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF FERRARA   (Italy)

Author keywords

Antitumor agent; Duocarmycin SA

Indexed keywords

ANTINEOPLASTIC AGENT; DUOCARMYCIN SA; METHYL 1,2,8,8A TETRAHYDROCYCLOPROPA[C]THIENO[3,2 E]INDOL 4 ONE 6 CARBOXYLATE DERIVATIVE; RACHELMYCIN; UNCLASSIFIED DRUG; YATAKEMYCIN;

ALKYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; ATOM; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA L 1210; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS, ALKYLATING; INDOLES; PYRROLES; SULFHYDRYL COMPOUNDS; THIOPHENES;

EID: 71849097198     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.10.063     Document Type: Article

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