SCOPUS 정보 검색 플랫폼

Volumn 66, Issue 7, 2001, Pages 2207-2216

Synthesis, chemical properties, and biological evaluation of CC-1065 and duocarmycin analogues incorporating the 5-methoxycarbonyl-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one alkylation subunit

(3) Boger, D L a Hughes, T V a Hedrick, M P a

a SCRIPPS RESEARCH INSTITUTE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL EVALUATION;

ALKYLATION; DNA; SUPRAMOLECULAR CHEMISTRY; X RAY ANALYSIS;

AROMATIC COMPOUNDS;

3 (5,6,7 TRIMETHOXYINDOL 2 CARBONYL) 1 (CHLOROMETHYL) 5 HYDROXY 6 METHOXYCARBONYL 1,2 DIHYDRO 3H BENZ[E]INDOLE; DUOCARMYCIN DERIVATIVE; N (5,6,7 TRIMETHOXYINDOL 2 CARBONYL) 5 METHOXYCARBONYL 1,2,9,9A TETRAHYDROCYCLOPROPA[C]BENZ[E]INDOL 4 ONE; N (TERT BUTYLOXYCARBONYL) 5 METHOXYCARBONYL 1,2,9,9A TETRAHYDROCYCLOPROPA[C]BENZ[E]INDOL 4 ONE; RACHELMYCIN; RACHELMYCIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL BINDING; CORRELATION FUNCTION; DNA ALKYLATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; STEREOCHEMISTRY; STEREOSPECIFICITY; X RAY ANALYSIS;

ALKYLATION; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, ALKYLATING; CRYSTALLOGRAPHY, X-RAY; DNA; INDOLES; INHIBITORY CONCENTRATION 50; KINETICS; LEUCOMYCINS; LEUKEMIA L1210; MICE; PYRROLES; PYRROLIDINONES;

EID: 0035815152 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo001772g Document Type: Article

Times cited : (51)

References (52)

1
- 0029782488
- (1996) Angew. Chem. Int. Ed. Engl. , vol.35 , pp. 1439
- Boger, D.L.¹ Johnson, D.S.²

2
- 0029053550
- (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 3642
- Boger, D.L.¹ Johnson, D.S.²

3
- 0000923199
- (1991) Chemtracts: Org. Chem. , vol.4 , pp. 329
- Boger, D.L.¹

4
- 0024240366
- (1988) Chem. Res. Toxicol. , vol.1 , pp. 315
- Warpehoski, M.A.¹ Hurley, L.H.²

5
- 33845376321
- (1986) Acc. Chem. Res. , vol.19 , pp. 230
- Hurley, L.H.¹ Needham-VanDevanter, D.R.²

6
- 0024393748
- (1989) J. Am. Chem. Soc. , vol.111 , pp. 6461
- Boger, D.L.¹ Ishizaki, T.² Wysocki R.J., Jr.³ Munk, S.A.⁴ Kitos, P.A.⁵ Suntornwat, O.⁶

7
- 0025119357
- (1990) J. Org. Chem. , vol.55 , pp. 5823
- Boger, D.L.¹ Ishizaki, T.² Kitos, P.A.³ Suntornwat, O.⁴

8
- 0025907919
- (1991) Bioorg. Med. Chem. Lett. , vol.1 , pp. 55
- Boger, D.L.¹ Ishizaki, T.² Zarrinmayeh, H.³ Kitos, P.A.⁴ Suntornwat, O.⁵

9
- 0025891696
- (1991) Bioorg. Med. Chem. Lett. , vol.1 , pp. 115
- Boger, D.L.¹ Ishizaki, T.² Sakya, S.M.³ Munk, S.A.⁴ Kitos, P.A.⁵ Jin, Q.⁶ Besterman, J.M.⁷

10
- 84994476837
- (1992) J. Am. Chem. Soc. , vol.114 , pp. 5487
- Boger, D.L.¹ Munk, S.A.²

11
- 0026638104
- (1992) J. Org. Chem. , vol.57 , pp. 2873
- Boger, D.L.¹ Yun, W.² Teegarden, B.R.³

12
- 0028036453
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 7996
- Boger, D.L.¹ Yun, W.²

13
- 0028920020
- (1995) J. Org. Chem. , vol.60 , pp. 1271
- Boger, D.L.¹ McKie, J.A.²

14
- 0029065554
- (1995) Bioorg. Med. Chem. , vol.3 , pp. 761
- Boger, D.L.¹ Yun, W.² Cai, H.³ Han, N.⁴

15
- 0028790373
- (1995) Bioorg. Med. Chem. , vol.3 , pp. 1429
- Boger, D.L.¹ Yun, W.² Han, N.³

16
- 0002617056
- (1997) Synlett , pp. 515
- Boger, D.L.¹ McKie, J.A.² Boyce, C.W.³

17
- 0032813670
- (1999) Synthesis , pp. 1505
- Boger, D.L.¹ Boyce, C.W.² Garbaccio, R.M.³ Searcey, M.⁴ Jin, Q.⁵

18
- 0029980340
- (1996) J. Org. Chem. , vol.61 , pp. 1710
- Boger, D.L.¹ McKie, J.A.² Cai, H.³ Cacciari, B.⁴ Baraldi, P.G.⁵

19
- 0030036747
- (1996) J. Org. Chem. , vol.61 , pp. 4894
- Boger, D.L.¹ Han, N.² Tarby, C.M.³ Boyce, C.W.⁴ Cai, H.⁵ Jin, Q.⁶ Kitos, P.A.⁷

20
- 0034733133
- (2000) J. Org. Chem. , vol.65 , pp. 4101
- Boger, D.L.¹ Santillán A., Jr.² Searcey, M.³ Brunette, S.R.⁴ Wolkenberg, S.E.⁵ Hedrick, M.P.⁶ Jin, Q.⁷

21
- 0033377095
- (1999) Acc. Chem. Res. , vol.32 , pp. 1043
- Boger, D.L.¹ Garbaccio, R.M.²

22
- 0031081549
- (1997) Bioorg. Med. Chem. , vol.5 , pp. 263
- Boger, D.L.¹ Garbaccio, R.M.²

23
- 0030904168
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 4987
- Boger, D.L.¹ Bollinger, B.² Hertzog, D.L.³ Johnson, D.S.⁴ Cai, H.⁵ Mésini, P.⁶ Garbaccio, R.M.⁷ Jin, Q.⁸ Kitos, P.A.⁹

24
- 0030760674
- (1997) J. Mol. Biol. , vol.272 , pp. 237
- Eis, P.G.¹ Smith, J.A.² Rydzewski, J.M.³ Case, D.A.⁴ Boger, D.L.⁵ Chazin, W.J.⁶

25
- 0033597629
- (1999) J. Am. Chem. Soc. , vol.121 , pp. 5645
- Schnell, J.R.¹ Ketchem, R.R.² Boger, D.L.³ Chazin, W.J.⁴

26
- 0034725557
- (2000) J. Mol. Biol. , vol.300 , pp. 1195
- Smith, J.A.¹ Bifulco, G.² Case, D.A.³ Boger, D.L.⁴ Gomes-Paloma, L.⁵ Chazin, W.J.⁶

27
- 0030970599
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 4977
- Boger, D.L.¹ Hertzog, D.L.² Bollinger, B.³ Johnson, D.S.⁴ Cai, H.⁵ Goldberg, J.⁶ Turnbull, P.⁷

28
- 0003592321
- (1997) J. Am. Chem. Soc. , vol.62 , pp. 88875
- Boger, D.L.¹ Garbaccio, R.M.² Jin, Q.³

29
- 0032545027
- (1998) J. Am. Chem. Soc. , vol.120 , pp. 11554
- Boger, D.L.¹ Santillán A., Jr.² Searcey, M.³ Jin, Q.⁴

30
- 0033000565
- (1999) J. Org. Chem. , vol.64 , pp. 5241
- Boger, D.L.¹ Santillán A., Jr.² Searcey, M.³ Jin, Q.⁴

31
- 0030882524
- (1997) J. Org. Chem. , vol.62 , pp. 5849
- Boger, D.L.¹ Turnbull, P.²

32
- 0032582736
- (1998) J. Org. Chem. , vol.63 , pp. 8004
- Boger, D.L.¹ Turnbull, P.²

33
- 0033597812
- (1999) J. Org. Chem. , vol.64 , pp. 5666
- Boger, D.L.¹ Garbaccio, R.M.²

34
- 0001699963
- (1997) Chem. Rev. , vol.97 , pp. 787
- Boger, D.L.¹ Boyce, C.W.² Garbaccio, R.M.³ Goldberg, J.⁴

35
- 0001977204
- (1977) Zh. Org. Khim. , vol.13 , pp. 2194
- Plakidin, V.L.¹ Vostrova, V.N.² Gnatyuk, P.P.³ Zadorozhnyi, N.M.⁴

36
- 0003713253
- (1970) Zh. Org. Khim. , vol.6 , pp. 1480
- Plakidin, V.L.¹ Zadorozhnyi, N.M.² Krasota, Z.I.³

37
- 37049130234
- (1966) J. Chem. Soc. C , pp. 523
- Birch, A.J.¹ Salahud-Din, M.² Smith, D.C.C.³

38
- 0031467660
- (1997) J. Org. Chem. , vol.62 , pp. 8868
- Patel, V.F.¹ Andis, S.L.² Enkema, J.K.³ Johnson, D.A.⁴ Kennedy, J.H.⁵ Mohamadi, F.⁶ Schultz, R.M.⁷ Soose, D.J.⁸ Spees, M.M.⁹

39
- 0032537208
- (1998) Tetrahedron Lett. , vol.39 , pp. 2227
- Boger, D.L.¹ Boyce, C.W.² Garbaccio, R.M.³ Searcey, M.⁴

40
- 0028036453
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 7996
- Boger, D.L.¹ Yun, W.²

41
- 0003592323
- note

42
- 0028085388
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 7573
- Warpehoski, M.A.¹ Harper, D.E.²

43
- 0028958933
- (1995) J. Am. Chem. Soc. , vol.117 , pp. 2951
- Warpehoski, M.A.¹ Harper, D.E.²

44
- 0030594978
- (1996) Bioorg. Med. Chem. Lett. , vol.6 , pp. 1955
- Boger, D.L.¹ Goldberg, J.² McKie, J.A.³

45
- 0031055494
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 311
- Boger, D.L.¹ McKie, J.A.² Nishi, T.³ Ogiku, T.⁴

46
- 0028024034
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 6461
- Boger, D.L.¹ Mésini, P.² Tarby, C.M.³

47
- 0028592579
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 11335
- Boger, D.L.¹ Mésini, P.²

48
- 0028920020
- (1995) J. Am. Chem. Soc. , vol.60 , pp. 1271
- Boger, D.L.¹ Mésini, P.²

49
- 0029813588
- (1996) J. Am. Chem. Soc. , vol.118 , pp. 8860
- Boger, D.L.¹ Jenkins, T.J.²

50
- 0025980193
- (1991) Tetrahedron , vol.47 , pp. 2661
- Boger, D.L.¹ Munk, S.A.² Zarrinmayeh, H.³ Ishizaki, T.⁴ Haught, J.⁵ Bina, M.⁶

51
- 0028095610
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 1635
- Boger, D.L.¹ Johnson, D.S.² Yun, W.³

52
- 0003490537
- note

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