Lycopene prevents 7-ketocholesterol-induced oxidative stress, cell cycle arrest and apoptosis in human macrophages

Journal of Nutritional Biochemistry

Volumn 21, Issue 1, 2010, Pages 34-46

  Palozza, Paola ^a   Simone, Rossella ^a   Catalano, Assunta ^a   Boninsegna, Alma ^a   Böhm, Volker ^b   Fröhlich, Kati ^b   Mele, Maria Cristina ^a   Monego, Giovanni ^a   Ranelletti, Franco O ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

7 Ketocholesterol; Apoptosis; Cell cycle; Lycopene; Oxidative stress

Indexed keywords

7 OXOCHOLESTEROL; BETA CAROTENE; CAROTENOID; CASPASE 3; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; LYCOPENE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OXYSTEROL; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MACROPHAGE; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

APOPTOSIS; CAROTENOIDS; CELL CYCLE; CELLS, CULTURED; DEOXYGUANOSINE; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; KETOCHOLESTEROLS; MACROPHAGES; NADPH OXIDASE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 71749099655     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2008.10.002     Document Type: Article

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