-
1
-
-
0028181737
-
Cytotoxicity of a Shiga toxin A subunit-CD4 fusion protein to human immunodeficiency virus-infected cells
-
Al-Jaufy A.Y., Haddad J.E., King S.R., McPhee R.A., and Jackson M.P. Cytotoxicity of a Shiga toxin A subunit-CD4 fusion protein to human immunodeficiency virus-infected cells. Infect. Immun. 62 (1994) 956-960
-
(1994)
Infect. Immun.
, vol.62
, pp. 956-960
-
-
Al-Jaufy, A.Y.1
Haddad, J.E.2
King, S.R.3
McPhee, R.A.4
Jackson, M.P.5
-
2
-
-
0028983125
-
Purification and characterization of a Shiga toxin A subunit-CD4 fusion protein cytotoxic to human immunodeficiency virus-infected cells
-
Al-Jaufy A.Y., King S.R., and Jackson M.P. Purification and characterization of a Shiga toxin A subunit-CD4 fusion protein cytotoxic to human immunodeficiency virus-infected cells. Infect. Immun. 63 (1995) 3073-3078
-
(1995)
Infect. Immun.
, vol.63
, pp. 3073-3078
-
-
Al-Jaufy, A.Y.1
King, S.R.2
Jackson, M.P.3
-
3
-
-
0032943892
-
Vascular endothelial growth factor chimeric toxin is highly active against endothelial cells
-
Arora N., Maood R., Zheng T., Cai J., Smith L., and Gill P.S. Vascular endothelial growth factor chimeric toxin is highly active against endothelial cells. Cancer Res. 59 (1999) 183-188
-
(1999)
Cancer Res.
, vol.59
, pp. 183-188
-
-
Arora, N.1
Maood, R.2
Zheng, T.3
Cai, J.4
Smith, L.5
Gill, P.S.6
-
4
-
-
0034804396
-
Functionally active VEGF fusion proteins
-
Backer M.V., and Backer J.M. Functionally active VEGF fusion proteins. Protein Expr. Purif. 23 (2001) 1-7
-
(2001)
Protein Expr. Purif.
, vol.23
, pp. 1-7
-
-
Backer, M.V.1
Backer, J.M.2
-
5
-
-
0035213434
-
Targeting endothelial cells overexpressing VEGFR-2: Selective toxicity of Shiga-like toxin-VEGF fusion proteins
-
Backer M.V., and Backer J.M. Targeting endothelial cells overexpressing VEGFR-2: Selective toxicity of Shiga-like toxin-VEGF fusion proteins. Bioconj. Chem. 12 (2001) 1066-1073
-
(2001)
Bioconj. Chem.
, vol.12
, pp. 1066-1073
-
-
Backer, M.V.1
Backer, J.M.2
-
6
-
-
0035816148
-
Shiga-like toxin-VEGF fusion proteins are selectively cytotoxic to endothelial cells overexpressing VEGFR-2
-
Backer M.V., Budker V.G., and Backer J.M. Shiga-like toxin-VEGF fusion proteins are selectively cytotoxic to endothelial cells overexpressing VEGFR-2. J. Control. Release 74 (2001) 349-355
-
(2001)
J. Control. Release
, vol.74
, pp. 349-355
-
-
Backer, M.V.1
Budker, V.G.2
Backer, J.M.3
-
7
-
-
0038402541
-
Humanized docking system for assembly of targeting drug delivery complexes
-
Backer M.V., Gaynutdinov T.I., Gorshkova I.I., Crouch R.J., Hu T., Aloise R., Arab M., Przekop K., and Backer J.M. Humanized docking system for assembly of targeting drug delivery complexes. J. Control. Release 89 (2003) 499-511
-
(2003)
J. Control. Release
, vol.89
, pp. 499-511
-
-
Backer, M.V.1
Gaynutdinov, T.I.2
Gorshkova, I.I.3
Crouch, R.J.4
Hu, T.5
Aloise, R.6
Arab, M.7
Przekop, K.8
Backer, J.M.9
-
8
-
-
33644701668
-
Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculature
-
Backer M.V., Gaynutdinov T.I., Patel V., Bandyopadhyaya A.K., Thirumamagal B.T.S., Tjarks W., Barth R., Claffey K.P., and Backer J.M. Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculature. Mol. Cancer Ther. 4 9 (2005) 1423-1429
-
(2005)
Mol. Cancer Ther.
, vol.4
, Issue.9
, pp. 1423-1429
-
-
Backer, M.V.1
Gaynutdinov, T.I.2
Patel, V.3
Bandyopadhyaya, A.K.4
Thirumamagal, B.T.S.5
Tjarks, W.6
Barth, R.7
Claffey, K.P.8
Backer, J.M.9
-
9
-
-
34147191481
-
Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF based probes
-
Backer M.V., Levashova Z., Patel V., Jehning B.T., Claffey K., Blankenberg F.G., and Backer J.M. Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF based probes. Nat. Med. 13 (2007) 504-509
-
(2007)
Nat. Med.
, vol.13
, pp. 504-509
-
-
Backer, M.V.1
Levashova, Z.2
Patel, V.3
Jehning, B.T.4
Claffey, K.5
Blankenberg, F.G.6
Backer, J.M.7
-
10
-
-
47949099628
-
Modes of resistance to antiangiogenic therapy
-
Bergers G., and Hanahan D. Modes of resistance to antiangiogenic therapy. Nat. Rev. Cancer 8 (2008) 592-603
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
11
-
-
0025944147
-
Interaction of vasculotropin/vascular endothelial cell growth factor with human umbilical vein endothelial cells: Binding, internalization, degradation, and biological effects
-
Bikfalvi A., Sauzeau C., Moukadiri H., Maclouf J., Busso N., Bryckaert M., Plouet J., and Tobelem G. Interaction of vasculotropin/vascular endothelial cell growth factor with human umbilical vein endothelial cells: Binding, internalization, degradation, and biological effects. J. Cell Physiol. 149 (1991) 50-59
-
(1991)
J. Cell Physiol.
, vol.149
, pp. 50-59
-
-
Bikfalvi, A.1
Sauzeau, C.2
Moukadiri, H.3
Maclouf, J.4
Busso, N.5
Bryckaert, M.6
Plouet, J.7
Tobelem, G.8
-
12
-
-
4544353770
-
Tumor imaging using a standardized radiolabeled adapter protein docked to vascular endothelial growth factor (VEGF)
-
Blankenberg F.G., Mandl S., Cao Y.-A., et al. Tumor imaging using a standardized radiolabeled adapter protein docked to vascular endothelial growth factor (VEGF). J. Nucl. Med. 45 (2004) 1373-1380
-
(2004)
J. Nucl. Med.
, vol.45
, pp. 1373-1380
-
-
Blankenberg, F.G.1
Mandl, S.2
Cao, Y.-A.3
-
13
-
-
71549138874
-
Noninvasive assessment of tumor VEGF receptors in response to treatment with pazopanib: A molecular imaging study
-
in press
-
Blankenberg F.G., Levashova L., Sarkar S.K., Pizzonia J., Backer M.V., and Backer J.M. Noninvasive assessment of tumor VEGF receptors in response to treatment with pazopanib: A molecular imaging study. Transl. Oncol. 3 1 (2010) in press
-
(2010)
Transl. Oncol.
, vol.3
, Issue.1
-
-
Blankenberg, F.G.1
Levashova, L.2
Sarkar, S.K.3
Pizzonia, J.4
Backer, M.V.5
Backer, J.M.6
-
14
-
-
49549123352
-
Vertical VEGF targeting: A combination of ligand blockade with receptor tyrosine kinase inhibition
-
Bozec A., Gros F.X., Penault-Llorca F., Formento P., Cayre A., Dental C., Etienne-Grimaldi M.C., Fischel J.L., and Milano G. Vertical VEGF targeting: A combination of ligand blockade with receptor tyrosine kinase inhibition. Eur. J. Cancer 44 (2008) 1922-1930
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 1922-1930
-
-
Bozec, A.1
Gros, F.X.2
Penault-Llorca, F.3
Formento, P.4
Cayre, A.5
Dental, C.6
Etienne-Grimaldi, M.C.7
Fischel, J.L.8
Milano, G.9
-
15
-
-
0030721959
-
The RNA-N-glycosidase activity of Shiga-like toxin I: Kinetic parameters of the native and activated toxin
-
Brigotti M., Carnicelli D., Alvergna P., Mazzaracchio R., Sperti S., and Montanaro L. The RNA-N-glycosidase activity of Shiga-like toxin I: Kinetic parameters of the native and activated toxin. Toxiconolgy 35 (1997) 1431-1437
-
(1997)
Toxiconolgy
, vol.35
, pp. 1431-1437
-
-
Brigotti, M.1
Carnicelli, D.2
Alvergna, P.3
Mazzaracchio, R.4
Sperti, S.5
Montanaro, L.6
-
16
-
-
0028861231
-
Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer
-
Brown L.F., Berse B., Jackman R.W., et al. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in breast cancer. Hum. Pathol. 26 (1995) 86-91
-
(1995)
Hum. Pathol.
, vol.26
, pp. 86-91
-
-
Brown, L.F.1
Berse, B.2
Jackman, R.W.3
-
17
-
-
33846885522
-
PET of vascular endothelial growth factor receptor expression
-
Cai W., Chen K., Mohamedali K.A., Cao Q., Gambhir S.S., Rosenblum M.G., and Chen X. PET of vascular endothelial growth factor receptor expression. J. Nucl. Med. 47 (2006) 2048-2056
-
(2006)
J. Nucl. Med.
, vol.47
, pp. 2048-2056
-
-
Cai, W.1
Chen, K.2
Mohamedali, K.A.3
Cao, Q.4
Gambhir, S.S.5
Rosenblum, M.G.6
Chen, X.7
-
18
-
-
33847118123
-
Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models
-
Chang Y.S., Adnane J., Trail P.A., Levy J., Henderson A., Xue D., Bortolon E., Ichetovkin M., Chen C., McNabola A., Wilkie D., Carter C.A., et al. Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models. Cancer Chemother. Pharm. 59 (2007) 561-574
-
(2007)
Cancer Chemother. Pharm.
, vol.59
, pp. 561-574
-
-
Chang, Y.S.1
Adnane, J.2
Trail, P.A.3
Levy, J.4
Henderson, A.5
Xue, D.6
Bortolon, E.7
Ichetovkin, M.8
Chen, C.9
McNabola, A.10
Wilkie, D.11
Carter, C.A.12
-
19
-
-
65349186800
-
Aflibercept (AVE0005): An alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors
-
Chu Q.S. Aflibercept (AVE0005): An alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors. Expert Opin. Biol. Ther. 9 2 (2009) 263-271
-
(2009)
Expert Opin. Biol. Ther.
, vol.9
, Issue.2
, pp. 263-271
-
-
Chu, Q.S.1
-
20
-
-
0030054914
-
Regulation of VEGF/VPF expression in tumor cells: Consequences for tumor growth and metastasis
-
Claffey K.P., and Robinson G.S. Regulation of VEGF/VPF expression in tumor cells: Consequences for tumor growth and metastasis. Cancer Metastasis Rev. 15 2 (1996) 165-176
-
(1996)
Cancer Metastasis Rev.
, vol.15
, Issue.2
, pp. 165-176
-
-
Claffey, K.P.1
Robinson, G.S.2
-
21
-
-
0037295311
-
DAB389EGF fusion protein therapy of refractory glioblastoma multiforme
-
Cohen K.A., Liu T., Bissonette R., Puri R.K., and Frankel A.E. DAB389EGF fusion protein therapy of refractory glioblastoma multiforme. Curr. Pharm. Biotechnol. 4 (2003) 39-49
-
(2003)
Curr. Pharm. Biotechnol.
, vol.4
, pp. 39-49
-
-
Cohen, K.A.1
Liu, T.2
Bissonette, R.3
Puri, R.K.4
Frankel, A.E.5
-
22
-
-
0030938919
-
Vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in normal and artherosclerotic human arteries
-
Couffinhal T., Kearney M., Witzenbichler B., Chen D., Murohara T., Losordo D.W., Symes J., and Isner J.M. Vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in normal and artherosclerotic human arteries. Am. J. Pathol. 150 (1997) 1673-1685
-
(1997)
Am. J. Pathol.
, vol.150
, pp. 1673-1685
-
-
Couffinhal, T.1
Kearney, M.2
Witzenbichler, B.3
Chen, D.4
Murohara, T.5
Losordo, D.W.6
Symes, J.7
Isner, J.M.8
-
23
-
-
64049108890
-
Resistance to EGF-R (erbB-1) and VEGF-R modulating agents
-
Dempke W.C., and Heinemann V. Resistance to EGF-R (erbB-1) and VEGF-R modulating agents. Eur. J. Cancer 45 7 (2009) 1117-1128
-
(2009)
Eur. J. Cancer
, vol.45
, Issue.7
, pp. 1117-1128
-
-
Dempke, W.C.1
Heinemann, V.2
-
24
-
-
53849133471
-
Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins
-
Deng Q., and Barbieri J.T. Molecular mechanisms of the cytotoxicity of ADP-ribosylating toxins. Annu. Rev. Microbiol. 62 (2008) 271-288
-
(2008)
Annu. Rev. Microbiol.
, vol.62
, pp. 271-288
-
-
Deng, Q.1
Barbieri, J.T.2
-
25
-
-
0031845912
-
Apoptosis rate can be accelerated or decelerated by overexpression or reduction of elongation factor-1α
-
Duttaroy A., Bourbeau D., Wang X.L., and Wang E. Apoptosis rate can be accelerated or decelerated by overexpression or reduction of elongation factor-1α. Exp. Cell Res. 238 1 (1998) 168-176
-
(1998)
Exp. Cell Res.
, vol.238
, Issue.1
, pp. 168-176
-
-
Duttaroy, A.1
Bourbeau, D.2
Wang, X.L.3
Wang, E.4
-
26
-
-
60649087564
-
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
-
Ebos J.M., Lee C.R., Cruz-Munoz W., Bjarnason G.A., Christensen J.G., and Kerbel R.S. Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell. 15 (2009) 232-239
-
(2009)
Cancer Cell.
, vol.15
, pp. 232-239
-
-
Ebos, J.M.1
Lee, C.R.2
Cruz-Munoz, W.3
Bjarnason, G.A.4
Christensen, J.G.5
Kerbel, R.S.6
-
27
-
-
47949089077
-
VEGF-targeted therapy: Mechanisms of anti-tumour activity
-
Ellis L.M., and Hicklin D.J. VEGF-targeted therapy: Mechanisms of anti-tumour activity. Nat. Rev. Cancer 8 (2008) 579-591
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 579-591
-
-
Ellis, L.M.1
Hicklin, D.J.2
-
28
-
-
66349093990
-
Vascular endothelial growth factor
-
Ferrara N. Vascular endothelial growth factor. Arterioscler. Thromb. Vasc. Biol. 29 6 (2009) 789-791
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, Issue.6
, pp. 789-791
-
-
Ferrara, N.1
-
29
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1 (1995) 27-31
-
(1995)
Nat. Med.
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
30
-
-
0031839132
-
Diphtheria toxin fusion proteins
-
Frankel A.E. (Ed), Springer, Berlin, Germany
-
Foss F.M., Saleh M.N., Krueger J.G., Nichols J.C., and Murphy J.R. Diphtheria toxin fusion proteins. In: Frankel A.E. (Ed). Clinical Applications of Immunotoxins (1998), Springer, Berlin, Germany 63-81
-
(1998)
Clinical Applications of Immunotoxins
, pp. 63-81
-
-
Foss, F.M.1
Saleh, M.N.2
Krueger, J.G.3
Nichols, J.C.4
Murphy, J.R.5
-
31
-
-
0041736005
-
Immunotoxin therapy of hematologic malignancies
-
Frankel A.E., Neville D.M., Bugge T.A., Kreitman R.J., and Leppla S.H. Immunotoxin therapy of hematologic malignancies. Semin. Oncol. 30 (2003) 545-557
-
(2003)
Semin. Oncol.
, vol.30
, pp. 545-557
-
-
Frankel, A.E.1
Neville, D.M.2
Bugge, T.A.3
Kreitman, R.J.4
Leppla, S.H.5
-
32
-
-
0034098351
-
Angiogenesis: New targets for the development of anticancer chemotherapies
-
Gourley M., and Williamson J.S. Angiogenesis: New targets for the development of anticancer chemotherapies. Curr. Pharm. Des. 6 (2000) 417-439
-
(2000)
Curr. Pharm. Des.
, vol.6
, pp. 417-439
-
-
Gourley, M.1
Williamson, J.S.2
-
33
-
-
63849189675
-
Molecular targeted therapies for solid tumors: Management of side effects
-
Grunwald V., Soltau J., Ivanyi P., Rentschler J., Reuter C., and Drevs J. Molecular targeted therapies for solid tumors: Management of side effects. Onkologie 32 3 (2009) 129-138
-
(2009)
Onkologie
, vol.32
, Issue.3
, pp. 129-138
-
-
Grunwald, V.1
Soltau, J.2
Ivanyi, P.3
Rentschler, J.4
Reuter, C.5
Drevs, J.6
-
34
-
-
63049088767
-
Renal effects of anti-angiogenesis therapy: Update for the internist
-
Gurevich F., and Perazella M.A. Renal effects of anti-angiogenesis therapy: Update for the internist. Am. J. Med. 122 4 (2009) 322-328
-
(2009)
Am. J. Med.
, vol.122
, Issue.4
, pp. 322-328
-
-
Gurevich, F.1
Perazella, M.A.2
-
35
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D., and Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86 3 (1996) 353-364
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
36
-
-
64749104426
-
Cutting off cancer's supply lines
-
Hayden E.C. Cutting off cancer's supply lines. Nature 458 (2009) 686
-
(2009)
Nature
, vol.458
, pp. 686
-
-
Hayden, E.C.1
-
37
-
-
49649083397
-
The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis
-
Heckman C.A., Holopainen T., Wirzenius M., Keskitalo S., Jeltsch M., Yla-Herttuala S., Wedge S.R., Jurgensmeier J.M., and Alitalo K. The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis. Cancer Res. 68 12 (2008) 4754-4762
-
(2008)
Cancer Res.
, vol.68
, Issue.12
, pp. 4754-4762
-
-
Heckman, C.A.1
Holopainen, T.2
Wirzenius, M.3
Keskitalo, S.4
Jeltsch, M.5
Yla-Herttuala, S.6
Wedge, S.R.7
Jurgensmeier, J.M.8
Alitalo, K.9
-
38
-
-
65549107675
-
Whatever happened to immunotoxins? Research, and hope are still alive
-
Holzman C. Whatever happened to immunotoxins? Research, and hope are still alive. J. Natl. Cancer Inst. 101 9 (2009) 624-625
-
(2009)
J. Natl. Cancer Inst.
, vol.101
, Issue.9
, pp. 624-625
-
-
Holzman, C.1
-
39
-
-
71549141008
-
Specific targeting of tumor endothelial cells by a Shiga-like Toxin-VEGF fusion protein as a novel treatment strategy for pancreatic cancer
-
Springer, Berlin, Heidelberg
-
Hotz H.G., Hotz B., Bhargava H., and Buhr J. Specific targeting of tumor endothelial cells by a Shiga-like Toxin-VEGF fusion protein as a novel treatment strategy for pancreatic cancer. Deutsche Gesellschaft für Chirurgie Vol. 35 (2006), Springer, Berlin, Heidelberg 5-6
-
(2006)
Deutsche Gesellschaft für Chirurgie
, vol.35
, pp. 5-6
-
-
Hotz, H.G.1
Hotz, B.2
Bhargava, H.3
Buhr, J.4
-
40
-
-
34247208168
-
Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF121/rGel
-
Hsu A.R., Cai W., Veeravagu A., Mohamedali K.A., Chen K., Kim S., Vogel H., Hou L.C., Tse V., Rosenblum M.G., and Chen X. Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF121/rGel. J. Nucl. Med. 48 3 (2007) 445-454
-
(2007)
J. Nucl. Med.
, vol.48
, Issue.3
, pp. 445-454
-
-
Hsu, A.R.1
Cai, W.2
Veeravagu, A.3
Mohamedali, K.A.4
Chen, K.5
Kim, S.6
Vogel, H.7
Hou, L.C.8
Tse, V.9
Rosenblum, M.G.10
Chen, X.11
-
41
-
-
0033520375
-
Different mechanisms of c-Jun NH(2)-terminal kinase-1 (JNK1) activation by ultraviolet-B radiation and by oxidative stressors
-
Iordanov M.S., and Magun B.E. Different mechanisms of c-Jun NH(2)-terminal kinase-1 (JNK1) activation by ultraviolet-B radiation and by oxidative stressors. J. Biol. Chem. 274 (1999) 25801-25806
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25801-25806
-
-
Iordanov, M.S.1
Magun, B.E.2
-
42
-
-
0030973162
-
Ribotoxic stress response: Activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA
-
Iordanov M.S., Pribnow D., Magun J.L., Dinh T.H., Pearson J.A., Chen S.L., and Magun B.E. Ribotoxic stress response: Activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA. Mol. Cell. Biol. 17 (1997) 3373-3381
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3373-3381
-
-
Iordanov, M.S.1
Pribnow, D.2
Magun, J.L.3
Dinh, T.H.4
Pearson, J.A.5
Chen, S.L.6
Magun, B.E.7
-
43
-
-
65549122619
-
Management of hypertension in angiogenesis inhibitor-treated patients
-
Izzedine H., Ederhy S., Goldwasser F., Soria J.C., Milano G., Cohen A., Khayat D., and Spano J.P. Management of hypertension in angiogenesis inhibitor-treated patients. Ann. Oncol. 20 5 (2009) 807-815
-
(2009)
Ann. Oncol.
, vol.20
, Issue.5
, pp. 807-815
-
-
Izzedine, H.1
Ederhy, S.2
Goldwasser, F.3
Soria, J.C.4
Milano, G.5
Cohen, A.6
Khayat, D.7
Spano, J.P.8
-
44
-
-
0036468930
-
A potential autocrine role for vascular endothelial growth factor in prostate cancer
-
Jackson M.W., Roberts J.S., Heckford S.E., et al. A potential autocrine role for vascular endothelial growth factor in prostate cancer. Cancer Res. 62 (2002) 854-859
-
(2002)
Cancer Res.
, vol.62
, pp. 854-859
-
-
Jackson, M.W.1
Roberts, J.S.2
Heckford, S.E.3
-
45
-
-
11844254414
-
Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy
-
Jain R.K. Normalization of tumor vasculature: An emerging concept in antiangiogenic therapy. Science 307 (2005) 58-62
-
(2005)
Science
, vol.307
, pp. 58-62
-
-
Jain, R.K.1
-
47
-
-
65049087191
-
Can tyrosine kinase inhibitors be discontinued in patients with metastatic renal cell carcinoma and a complete response to treatment? A multicentre, retrospective analysis
-
Johannsen M., Florcken A., Bex A., Roigas J., Cosentino M., Ficarra V., Kloeters C., Rief M., Rogalla P., Miller K., and Grunwald V. Can tyrosine kinase inhibitors be discontinued in patients with metastatic renal cell carcinoma and a complete response to treatment? A multicentre, retrospective analysis. Eur. Urol. 55 (2009) 1430-1439
-
(2009)
Eur. Urol.
, vol.55
, pp. 1430-1439
-
-
Johannsen, M.1
Florcken, A.2
Bex, A.3
Roigas, J.4
Cosentino, M.5
Ficarra, V.6
Kloeters, C.7
Rief, M.8
Rogalla, P.9
Miller, K.10
Grunwald, V.11
-
48
-
-
33746548452
-
Predicting benefit from antiangiogenic agents in malignancy
-
Jubb A.M., Oates A.J., Holden S., and Koeppen H. Predicting benefit from antiangiogenic agents in malignancy. Nat. Rev. Cancer 6 (2006) 626-635
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 626-635
-
-
Jubb, A.M.1
Oates, A.J.2
Holden, S.3
Koeppen, H.4
-
49
-
-
0025280956
-
Recent advances in understanding the pathogenesis of the hemolytic uremic syndromes
-
Kaplan B.S., Cleary T.G., and Obrig T.G. Recent advances in understanding the pathogenesis of the hemolytic uremic syndromes. Pediatr. Nephrol. 4 (1990) 276-283
-
(1990)
Pediatr. Nephrol.
, vol.4
, pp. 276-283
-
-
Kaplan, B.S.1
Cleary, T.G.2
Obrig, T.G.3
-
50
-
-
2942615257
-
The anti-angiogenesis basis of metronomic chemotherapy
-
Kerbel R.S., and Kamen B.A. The anti-angiogenesis basis of metronomic chemotherapy. Nat. Rev. Cancer 4 (2004) 425-436
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 425-436
-
-
Kerbel, R.S.1
Kamen, B.A.2
-
51
-
-
0034214159
-
Vascular endothelial growth factor/KDR activated microvessel density versus CD31 standard microvessel density in non-small cell lung cancer
-
Koukourakis M.I., Giatromanolaki A., Thorpe P.E., et al. Vascular endothelial growth factor/KDR activated microvessel density versus CD31 standard microvessel density in non-small cell lung cancer. Cancer Res. 60 (2000) 3088-3095
-
(2000)
Cancer Res.
, vol.60
, pp. 3088-3095
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Thorpe, P.E.3
-
52
-
-
33748309412
-
Immunotoxins for targeted cancer therapy
-
Kreitman R.J. Immunotoxins for targeted cancer therapy. AAPS J. 8 3 (2006) E532-E551
-
(2006)
AAPS J.
, vol.8
, Issue.3
-
-
Kreitman, R.J.1
-
53
-
-
64349108724
-
Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignancies
-
Kreitman R.J. Recombinant immunotoxins containing truncated bacterial toxins for the treatment of hematologic malignancies. BioDrugs 23 1 (2009) 1-13
-
(2009)
BioDrugs
, vol.23
, Issue.1
, pp. 1-13
-
-
Kreitman, R.J.1
-
54
-
-
34447322566
-
Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity
-
Kumar R., Knick V.B., Rudolph S.K., Johnson J.H., Crosby R.M., Crouthamel M.-C., Hopper T.M., Miller C.G., Harrington L.E., Onori J.A., Mullin R.J., Gilmer T.M., et al. Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity. Mol. Cancer Ther. 6 (2007) 2012-2021
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 2012-2021
-
-
Kumar, R.1
Knick, V.B.2
Rudolph, S.K.3
Johnson, J.H.4
Crosby, R.M.5
Crouthamel, M.-C.6
Hopper, T.M.7
Miller, C.G.8
Harrington, L.E.9
Onori, J.A.10
Mullin, R.J.11
Gilmer, T.M.12
-
56
-
-
10944242667
-
Antiangiogenic therapy: Creating a unique "window" of opportunity
-
Lin M.I., and Sessa W.C. Antiangiogenic therapy: Creating a unique "window" of opportunity. Cancer Cell 6 (2004) 529-531
-
(2004)
Cancer Cell
, vol.6
, pp. 529-531
-
-
Lin, M.I.1
Sessa, W.C.2
-
57
-
-
0037447150
-
A diphtheria toxin-epidermel growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells
-
Liu T.F., Cohen K.A., Ramag J.G., Willingham M.C., Thorburn A.M., and Frankel A.E. A diphtheria toxin-epidermel growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells. Cancer Res. 63 8 (2003) 1834-1837
-
(2003)
Cancer Res.
, vol.63
, Issue.8
, pp. 1834-1837
-
-
Liu, T.F.1
Cohen, K.A.2
Ramag, J.G.3
Willingham, M.C.4
Thorburn, A.M.5
Frankel, A.E.6
-
58
-
-
60649116477
-
Silencing or fueling metastasis with VEGF inhibitors: Antiangiogenesis revisited
-
Loges S., Mazzone M., Hohensinner P., and Carmeliet P. Silencing or fueling metastasis with VEGF inhibitors: Antiangiogenesis revisited. Cancer Cell 15 (2009) 167-170
-
(2009)
Cancer Cell
, vol.15
, pp. 167-170
-
-
Loges, S.1
Mazzone, M.2
Hohensinner, P.3
Carmeliet, P.4
-
59
-
-
63749125392
-
VEGFs and receptors involved in angiogenesis versus lymphangiogenesis
-
Lohela M., Bry M., Tammela T., and Alitalo K. VEGFs and receptors involved in angiogenesis versus lymphangiogenesis. Curr. Opin. Cell Biol. 21 2 (2009) 154-165
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, Issue.2
, pp. 154-165
-
-
Lohela, M.1
Bry, M.2
Tammela, T.3
Alitalo, K.4
-
60
-
-
33749441325
-
Rapid vascular regrowth in tumors after reversal of VEGF inhibition
-
Mancuso M.R., Davis R., Norberg S.M., O'Brien S., Sennino B., Nakahara T., Yao V.J., Inai T., Brooks P., Freimark B., Shalinsky D.R., Hu-Lowe D.D., et al. Rapid vascular regrowth in tumors after reversal of VEGF inhibition. J. Clin. Invest. 116 (2006) 2610-2621
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2610-2621
-
-
Mancuso, M.R.1
Davis, R.2
Norberg, S.M.3
O'Brien, S.4
Sennino, B.5
Nakahara, T.6
Yao, V.J.7
Inai, T.8
Brooks, P.9
Freimark, B.10
Shalinsky, D.R.11
Hu-Lowe, D.D.12
-
61
-
-
12144290647
-
Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesis
-
Manley P.W., Bold G., Bruggen J., et al. Advances in the structural biology, design and clinical development of VEGF-R kinase inhibitors for the treatment of angiogenesis. Biochim. Biophys. Acta 1697 (2004) 17-27
-
(2004)
Biochim. Biophys. Acta
, vol.1697
, pp. 17-27
-
-
Manley, P.W.1
Bold, G.2
Bruggen, J.3
-
62
-
-
12244301581
-
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
-
Mendel D.B., Laird A.D., Xin X., Louie S.G., Christensen J.G., Li G., Schreck R.E., Abrams T.J., Ngai T.J., Lee L.B., Murray L.J., Carver J., et al. In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship. Clin. Cancer Res. 9 (2003) 327-337
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 327-337
-
-
Mendel, D.B.1
Laird, A.D.2
Xin, X.3
Louie, S.G.4
Christensen, J.G.5
Li, G.6
Schreck, R.E.7
Abrams, T.J.8
Ngai, T.J.9
Lee, L.B.10
Murray, L.J.11
Carver, J.12
-
63
-
-
33845314445
-
Inhibition of prostate tumor growth and bone remodeling by the vascular targeting agent VEGF121/rGel
-
Mohamedali K.A., Poblenz A.T., Sikes C.R., Navone N.M., Thorpe P.E., Darnay B.G., and Rosenblum M.G. Inhibition of prostate tumor growth and bone remodeling by the vascular targeting agent VEGF121/rGel. Cancer Res. 66 22 (2006) 10919-10928
-
(2006)
Cancer Res.
, vol.66
, Issue.22
, pp. 10919-10928
-
-
Mohamedali, K.A.1
Poblenz, A.T.2
Sikes, C.R.3
Navone, N.M.4
Thorpe, P.E.5
Darnay, B.G.6
Rosenblum, M.G.7
-
64
-
-
0023234461
-
Pathogenesis of haemolytic uraemic syndrome (Letter)
-
Obrig T.G., Del Vecchio P.J., Karmali M.A., Petric M., Moran T.P., and Judge T.K. Pathogenesis of haemolytic uraemic syndrome (Letter). Lancet 2 (1987) 687
-
(1987)
Lancet
, vol.2
, pp. 687
-
-
Obrig, T.G.1
Del Vecchio, P.J.2
Karmali, M.A.3
Petric, M.4
Moran, T.P.5
Judge, T.K.6
-
65
-
-
0027185787
-
Endothelial heterogeneity in Shiga toxin receptors and responses
-
Obrig T., Louise C.B., Lingwood C.A., Boyd B., Barley-Maloney L., and Daniel T.O. Endothelial heterogeneity in Shiga toxin receptors and responses. J. Biol. Chem. 268 (1993) 15484-15488
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15484-15488
-
-
Obrig, T.1
Louise, C.B.2
Lingwood, C.A.3
Boyd, B.4
Barley-Maloney, L.5
Daniel, T.O.6
-
66
-
-
0019785229
-
Subunit structure of Shigella cytotoxin
-
Olsnes S., Reisbig R., and Eiklid K. Subunit structure of Shigella cytotoxin. J. Biol. Chem. 256 (1981) 8732-8738
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 8732-8738
-
-
Olsnes, S.1
Reisbig, R.2
Eiklid, K.3
-
67
-
-
0031564123
-
Targeting the tumor vasculature: Inhibition of tumor growth by a vascular endothelial growth factor-toxin conjugate
-
Olson T.A., Mohanraj D., Roy S., and Ramakrishnan S. Targeting the tumor vasculature: Inhibition of tumor growth by a vascular endothelial growth factor-toxin conjugate. Int. J. Cancer 73 (1997) 865-870
-
(1997)
Int. J. Cancer
, vol.73
, pp. 865-870
-
-
Olson, T.A.1
Mohanraj, D.2
Roy, S.3
Ramakrishnan, S.4
-
68
-
-
50149109090
-
Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and VEGFR-3 kinase inhibitors cediranib and vandetanib
-
Padera T.P., Kuo A.H., Hoshida T., Liao S., Lobo J., Kozak K.R., Fukumura D., and Jain R.K. Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and VEGFR-3 kinase inhibitors cediranib and vandetanib. Mol. Cancer Ther. 7 8 (2008) 2272-2279
-
(2008)
Mol. Cancer Ther.
, vol.7
, Issue.8
, pp. 2272-2279
-
-
Padera, T.P.1
Kuo, A.H.2
Hoshida, T.3
Liao, S.4
Lobo, J.5
Kozak, K.R.6
Fukumura, D.7
Jain, R.K.8
-
69
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes M., Allen E., Hudock J., Takeda T., Okuyama H., Vinals F., Inoue M., Bergers G., Hanahan D., and Casanovas O. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15 (2009) 220-231
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Vinals, F.6
Inoue, M.7
Bergers, G.8
Hanahan, D.9
Casanovas, O.10
-
70
-
-
52049113198
-
Vessel fractions in tumor xenografts depicted by flow- or contrast-sensitive three-dimensional high-frequency Doppler ultrasound respond differently to antiangiogenic treatment
-
Palmowski M., Huppert J., Hauff P., Reinhardt M., Schreiner K., Socher M.A., Hallscheidt P., Kauffmann G.W., Semmler W., and Kiessling F. Vessel fractions in tumor xenografts depicted by flow- or contrast-sensitive three-dimensional high-frequency Doppler ultrasound respond differently to antiangiogenic treatment. Cancer Res. 68 (2008) 7042-7049
-
(2008)
Cancer Res.
, vol.68
, pp. 7042-7049
-
-
Palmowski, M.1
Huppert, J.2
Hauff, P.3
Reinhardt, M.4
Schreiner, K.5
Socher, M.A.6
Hallscheidt, P.7
Kauffmann, G.W.8
Semmler, W.9
Kiessling, F.10
-
71
-
-
33745571528
-
Immunotoxin therapy of cancer
-
Pastan I., Hassan R., Fitzgerald D.J., and Kreitman R.J. Immunotoxin therapy of cancer. Nat. Rev. Cancer 6 7 (2006) 559-565
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.7
, pp. 559-565
-
-
Pastan, I.1
Hassan, R.2
Fitzgerald, D.J.3
Kreitman, R.J.4
-
72
-
-
61349190353
-
Design, synthesis and characterization of N9/N7-substituted 6-aminopurines as VEGF-R and EGF-R inhibitors
-
Peifer C., Buhler S., Hauser D., Kinkel K., Totzke F., Schachtele C., and Laufer S. Design, synthesis and characterization of N9/N7-substituted 6-aminopurines as VEGF-R and EGF-R inhibitors. Eur. J. Med. Chem. 44 4 (2009) 1788-1793
-
(2009)
Eur. J. Med. Chem.
, vol.44
, Issue.4
, pp. 1788-1793
-
-
Peifer, C.1
Buhler, S.2
Hauser, D.3
Kinkel, K.4
Totzke, F.5
Schachtele, C.6
Laufer, S.7
-
73
-
-
66249135629
-
Combined inhibition of the VEGFR and EGFR signaling pathways in the treatment of NSCLC
-
Pennell N.A., and Lynch Jr. T.J. Combined inhibition of the VEGFR and EGFR signaling pathways in the treatment of NSCLC. Oncologist 14 4 (2009) 399-411
-
(2009)
Oncologist
, vol.14
, Issue.4
, pp. 399-411
-
-
Pennell, N.A.1
Lynch Jr., T.J.2
-
74
-
-
51249107097
-
Targeted therapy of cancer using diphtheria toxin-derived immunotoxins
-
Potala S., Sahoo S.K., and Verma R.S. Targeted therapy of cancer using diphtheria toxin-derived immunotoxins. Drug Discov. Today 13 17-18 (2008) 807-815
-
(2008)
Drug Discov. Today
, vol.13
, Issue.17-18
, pp. 807-815
-
-
Potala, S.1
Sahoo, S.K.2
Verma, R.S.3
-
75
-
-
0036831559
-
Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy?
-
Rafii S., Lyden D., Benezra R., Hattori K., and Heissig B. Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy?. Nat. Rev. Cancer 2 (2002) 826-835
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 826-835
-
-
Rafii, S.1
Lyden, D.2
Benezra, R.3
Hattori, K.4
Heissig, B.5
-
76
-
-
0029915612
-
Vascular endothelial growth factor-toxin conjugate specifically inhibits KDR/flk-1 positive endothelial cell proliferation in vitro and angiogenesis in vivo
-
Ramakrishnan S., Olson T.A., Bauch V.L., and Mohanraj D. Vascular endothelial growth factor-toxin conjugate specifically inhibits KDR/flk-1 positive endothelial cell proliferation in vitro and angiogenesis in vivo. Cancer Res. 56 (1996) 1324-1330
-
(1996)
Cancer Res.
, vol.56
, pp. 1324-1330
-
-
Ramakrishnan, S.1
Olson, T.A.2
Bauch, V.L.3
Mohanraj, D.4
-
77
-
-
20344368810
-
The vascular-ablative agent VEGF(121)/rGel inhibits pulmonary metastases of MDA-MB-231 breast tumors
-
Ran S., Mohamedali K.A., Luster T.A., Thorpe P.E., and Rosenblum M.G. The vascular-ablative agent VEGF(121)/rGel inhibits pulmonary metastases of MDA-MB-231 breast tumors. Neoplasia (New York) 7 5 (2005) 486-496
-
(2005)
Neoplasia (New York)
, vol.7
, Issue.5
, pp. 486-496
-
-
Ran, S.1
Mohamedali, K.A.2
Luster, T.A.3
Thorpe, P.E.4
Rosenblum, M.G.5
-
79
-
-
61649123322
-
Angiogenesis and antiangiogenic therapy in non-Hodgkin's lymphoma
-
Ruan J., Hajjar K., Rafii S., and Leonard J.P. Angiogenesis and antiangiogenic therapy in non-Hodgkin's lymphoma. Ann. Oncol. 20 3 (2009) 413-424
-
(2009)
Ann. Oncol.
, vol.20
, Issue.3
, pp. 413-424
-
-
Ruan, J.1
Hajjar, K.2
Rafii, S.3
Leonard, J.P.4
-
80
-
-
0034638923
-
Mechanisms of angiogenesis and their use in the inhibition of tumor growth and metastasis
-
Saaristo A., Karpanen T., and Alitalo K. Mechanisms of angiogenesis and their use in the inhibition of tumor growth and metastasis. Oncogene 19 (2000) 6122-6129
-
(2000)
Oncogene
, vol.19
, pp. 6122-6129
-
-
Saaristo, A.1
Karpanen, T.2
Alitalo, K.3
-
81
-
-
0024564286
-
-
Sandvig K., Olsnes S., Brown J., Peterson O., and Van Beurs B. J. Cell Biol. 108 (1989) 1331-1343
-
(1989)
J. Cell Biol.
, vol.108
, pp. 1331-1343
-
-
Sandvig, K.1
Olsnes, S.2
Brown, J.3
Peterson, O.4
Van Beurs, B.5
-
82
-
-
0024558887
-
Shiga toxin, Shiga-like toxin II variant, and ricin are all single-site RNA N-glycosidases of 28 S RNA when microinjected into Xenopus oocytes
-
Saxena S.K., O'Brien A.D., and Ackerman E.J. Shiga toxin, Shiga-like toxin II variant, and ricin are all single-site RNA N-glycosidases of 28 S RNA when microinjected into Xenopus oocytes. J. Biol. Chem. 264 (1989) 596-601
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 596-601
-
-
Saxena, S.K.1
O'Brien, A.D.2
Ackerman, E.J.3
-
83
-
-
67649965962
-
Comparative VEGF receptor tyrosine kinase modeling for the development of highly specific inhibitors of tumor angiogenesis
-
Schmidt U., Ahmed J., Michalsky E., Hoepfner M., and Preissner R. Comparative VEGF receptor tyrosine kinase modeling for the development of highly specific inhibitors of tumor angiogenesis. Genome Inf. Serv. 20 (2008) 243-251
-
(2008)
Genome Inf. Serv.
, vol.20
, pp. 243-251
-
-
Schmidt, U.1
Ahmed, J.2
Michalsky, E.3
Hoepfner, M.4
Preissner, R.5
-
84
-
-
12244292196
-
Differentiation and definition of vascular-targeted therapies
-
Siemann D.W., Bibby M.C., Dark G.G., Dicker A.P., Eskens F.A., Horsman M.R., Marme D., and Lorusso P.M. Differentiation and definition of vascular-targeted therapies. Clin. Cancer Res. 11 2 Pt 1 (2005) 416-420
-
(2005)
Clin. Cancer Res.
, vol.11
, Issue.2 PART 1
, pp. 416-420
-
-
Siemann, D.W.1
Bibby, M.C.2
Dark, G.G.3
Dicker, A.P.4
Eskens, F.A.5
Horsman, M.R.6
Marme, D.7
Lorusso, P.M.8
-
86
-
-
57349179851
-
Pazopnib, a VEGF receptor tyrosine kinase inhibitor for cancer therapy
-
Sloan B., and Scheinfeld N.S. Pazopnib, a VEGF receptor tyrosine kinase inhibitor for cancer therapy. Curr. Opin. Invest. Drugs 9 (2008) 1324-1335
-
(2008)
Curr. Opin. Invest. Drugs
, vol.9
, pp. 1324-1335
-
-
Sloan, B.1
Scheinfeld, N.S.2
-
87
-
-
34548101663
-
Acute pharmacodynamic and antivascular effects of the vascular endothelial growth factor signaling inhibitor AZD2171 in Calu-6 human lung tumor xenografts
-
Smith N.R., James N.H., Oakley I., Wainwright A., Copley C., Kendrew J., Womersley L.M., Jürgensmeier J.M., Wedge S.R., and Barry S.T. Acute pharmacodynamic and antivascular effects of the vascular endothelial growth factor signaling inhibitor AZD2171 in Calu-6 human lung tumor xenografts. Mol. Cancer Ther. 6 8 (2007) 2198-2208
-
(2007)
Mol. Cancer Ther.
, vol.6
, Issue.8
, pp. 2198-2208
-
-
Smith, N.R.1
James, N.H.2
Oakley, I.3
Wainwright, A.4
Copley, C.5
Kendrew, J.6
Womersley, L.M.7
Jürgensmeier, J.M.8
Wedge, S.R.9
Barry, S.T.10
-
88
-
-
65549111254
-
Synthesis of quinazolines as tyrosine kinase inhibitors
-
Srivastava S.K., Kumar V., Agarwal S.K., Mukherjee R., and Burman A.C. Synthesis of quinazolines as tyrosine kinase inhibitors. Curr. Med. Chem. AntiCancer Agents 9 3 (2009) 246-275
-
(2009)
Curr. Med. Chem. AntiCancer Agents
, vol.9
, Issue.3
, pp. 246-275
-
-
Srivastava, S.K.1
Kumar, V.2
Agarwal, S.K.3
Mukherjee, R.4
Burman, A.C.5
-
89
-
-
33747229123
-
Ribosome-inactivating proteins: Progress and problems
-
Stirpe F., and Battelli M.G. Ribosome-inactivating proteins: Progress and problems. Cell Mol. Life Sci. 63 16 (2006) 1850-1866
-
(2006)
Cell Mol. Life Sci.
, vol.63
, Issue.16
, pp. 1850-1866
-
-
Stirpe, F.1
Battelli, M.G.2
-
90
-
-
0019212385
-
Gelonin, a new inhibitor of protein synthesis, nontoxic to intact cells. Isolation, characterization, and preparation of cytotoxic complexes with concanavalin A
-
Stirpe F., Olsnes S., and Pihl A. Gelonin, a new inhibitor of protein synthesis, nontoxic to intact cells. Isolation, characterization, and preparation of cytotoxic complexes with concanavalin A. J. Biol. Chem. 255 (1980) 6947-6953
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 6947-6953
-
-
Stirpe, F.1
Olsnes, S.2
Pihl, A.3
-
91
-
-
24944493848
-
Phase I clinical trial of the anti-CD-33 immunotoxin HuM195/rGel
-
Talpaz M., Kantarjian H., Freireich E., Lopez V., Zhang W., Cortes-Franco J., Scheinberg D., and Rosenblum M.G. Phase I clinical trial of the anti-CD-33 immunotoxin HuM195/rGel. Am. Assoc. Cancer Res. 44 (2003) 1066
-
(2003)
Am. Assoc. Cancer Res.
, vol.44
, pp. 1066
-
-
Talpaz, M.1
Kantarjian, H.2
Freireich, E.3
Lopez, V.4
Zhang, W.5
Cortes-Franco, J.6
Scheinberg, D.7
Rosenblum, M.G.8
-
93
-
-
0000899171
-
Phase I dose escalation study of the safety, tolerability, pharmacokinetics and biologic effects of DAB389-EGF in patient with solid malignances that express EGF receptors
-
Theodoulou M., Baselga J., Scher H., Dantis L., Trainor K., Mendelsohn J., Howes L., Elledge R., Ravdin P., Bacha P., Brandt-Sarif T., and Osborne K. Phase I dose escalation study of the safety, tolerability, pharmacokinetics and biologic effects of DAB389-EGF in patient with solid malignances that express EGF receptors. Proc. ASCO 14 (1995) 480
-
(1995)
Proc. ASCO
, vol.14
, pp. 480
-
-
Theodoulou, M.1
Baselga, J.2
Scher, H.3
Dantis, L.4
Trainor, K.5
Mendelsohn, J.6
Howes, L.7
Elledge, R.8
Ravdin, P.9
Bacha, P.10
Brandt-Sarif, T.11
Osborne, K.12
-
94
-
-
0037373826
-
The first international converence on vascular targeting: Meeting overview
-
Thorpe P.E., Chaplin D.J., and Blakey D.C. The first international converence on vascular targeting: Meeting overview. Cancer Res. 63 5 (2003) 1144-1147
-
(2003)
Cancer Res.
, vol.63
, Issue.5
, pp. 1144-1147
-
-
Thorpe, P.E.1
Chaplin, D.J.2
Blakey, D.C.3
-
95
-
-
0031466510
-
Renal dysfunction accounts for the dose limiting toxicity of DT390anti-CD3sFv, a potential new recombinant anti-GVHD immunotoxin
-
Vallera D.A., Panoskaltsis-Mortari A., and Blazar B.R. Renal dysfunction accounts for the dose limiting toxicity of DT390anti-CD3sFv, a potential new recombinant anti-GVHD immunotoxin. Protein Eng. 10 (1997) 1071-1076
-
(1997)
Protein Eng.
, vol.10
, pp. 1071-1076
-
-
Vallera, D.A.1
Panoskaltsis-Mortari, A.2
Blazar, B.R.3
-
96
-
-
62449192134
-
Tyrosine kinase inhibitors of VEGF receptors: Clinical issues and remaining questions
-
van Cruijsen H., van der Veldt A., and Hoekman K. Tyrosine kinase inhibitors of VEGF receptors: Clinical issues and remaining questions. Front. Biosci. 14 (2009) 2248-2268
-
(2009)
Front. Biosci.
, vol.14
, pp. 2248-2268
-
-
van Cruijsen, H.1
van der Veldt, A.2
Hoekman, K.3
-
97
-
-
0037062464
-
In vitro and in vivo studies of a VEGF121/rGelonin chimeric fusion toxin targeting the neovasculature of solid tumors
-
Veenendaal L.M., Jin H., Ran S., et al. In vitro and in vivo studies of a VEGF121/rGelonin chimeric fusion toxin targeting the neovasculature of solid tumors. Proc. Natl. Acad. Sci. USA 99 (2002) 7866-7871
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7866-7871
-
-
Veenendaal, L.M.1
Jin, H.2
Ran, S.3
-
98
-
-
0033047875
-
VEGFs, receptors and angiogenesis
-
Veikkola T., and Alitalo K. VEGFs, receptors and angiogenesis. Semin. Cancer Biol. 9 3 (1999) 211-220
-
(1999)
Semin. Cancer Biol.
, vol.9
, Issue.3
, pp. 211-220
-
-
Veikkola, T.1
Alitalo, K.2
-
99
-
-
0034650802
-
Regulation of angiogenesis via vascular endothelial growth factor receptors
-
Veikkola T., Karkkainen M., Claesson-Welsh L., and Alitalo K. Regulation of angiogenesis via vascular endothelial growth factor receptors. Cancer Res. 60 (2000) 203-212
-
(2000)
Cancer Res.
, vol.60
, pp. 203-212
-
-
Veikkola, T.1
Karkkainen, M.2
Claesson-Welsh, L.3
Alitalo, K.4
-
100
-
-
36749060685
-
A new PET tracer specific for vascular endothelial growth factor receptor 2
-
Wang H., Cai W., Chen K., Li Z.-B., Kashefi A., He L., and Chen X. A new PET tracer specific for vascular endothelial growth factor receptor 2. Eur. J. Nucl. Med. Mol. Imaging 34 (2007) 2001-2010
-
(2007)
Eur. J. Nucl. Med. Mol. Imaging
, vol.34
, pp. 2001-2010
-
-
Wang, H.1
Cai, W.2
Chen, K.3
Li, Z.-B.4
Kashefi, A.5
He, L.6
Chen, X.7
-
101
-
-
62649089820
-
Site-specifically biotinylated VEGF(121) for near-infrared fluorescence imaging of tumor angiogenesis
-
Wang H., Chen K., Niu G., and Chen X. Site-specifically biotinylated VEGF(121) for near-infrared fluorescence imaging of tumor angiogenesis. Mol. Pharm. 6 1 (2009) 285-294
-
(2009)
Mol. Pharm.
, vol.6
, Issue.1
, pp. 285-294
-
-
Wang, H.1
Chen, K.2
Niu, G.3
Chen, X.4
-
102
-
-
33746961739
-
Mechanisms of disease: Oncogene addiction-A rationale for molecular targeting in cancer therapy
-
Weinstein I.B., and Joe A.K. Mechanisms of disease: Oncogene addiction-A rationale for molecular targeting in cancer therapy. Nat. Clin. Pract. Oncol. 3 (2006) 448-457
-
(2006)
Nat. Clin. Pract. Oncol.
, vol.3
, pp. 448-457
-
-
Weinstein, I.B.1
Joe, A.K.2
-
104
-
-
0031589140
-
Comparison of ribosome-inactivating proteins in the induction of apoptosis
-
Williams J.M., Lea N., Lord J.M., Roberts L.M., Milford D.V., and Taylor C.M. Comparison of ribosome-inactivating proteins in the induction of apoptosis. Toxicol. Lett. 91 2 (1997) 121-127
-
(1997)
Toxicol. Lett.
, vol.91
, Issue.2
, pp. 121-127
-
-
Williams, J.M.1
Lea, N.2
Lord, J.M.3
Roberts, L.M.4
Milford, D.V.5
Taylor, C.M.6
-
105
-
-
0032192326
-
Quantification of infarct size on focal cerebral ischemia model of rats using a simple and economical method
-
Yang Y., Shuaib A., and Li Q. Quantification of infarct size on focal cerebral ischemia model of rats using a simple and economical method. J. Neurosci. Methods 84 (1998) 9-16
-
(1998)
J. Neurosci. Methods
, vol.84
, pp. 9-16
-
-
Yang, Y.1
Shuaib, A.2
Li, Q.3
|